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  1. 1221
    “…The study will conform to clinical practice guidelines and will follow the recommendations of the Declaration of Helsinki. The protocol was approved on November 2009 by Maggiore Hospital Ethical Review Board (ID CE09079). …”
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    The NOTA study: non-operative treatment for acute appendicitis: prospective study on the efficacy and safety of antibiotic treatment (amoxicillin and clavulanic acid) in patients with right sided lower abdominal pain
  2. 1222
    “…Planned analyses are in full compliance with the principles of the Declaration of Helsinki. Data collection will be completed by early spring 2012. …”
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    Hypertension Analysis of stress Reduction using Mindfulness meditatiON and Yoga (The HARMONY Study): study protocol of a randomised control trial
  3. 1223
    “…TRIAL REGISTRATION: Netherlands Trial Register (NTR): NTR2902 This trial will be conducted in accordance with the protocol and in compliance with the moral, ethical, and scientific principles governing clinical research as set out in the Declaration of Helsinki (1989) and Good Clinical Practice (GCP). The department of radiology of the Academic Medical Center of Amsterdam is responsible for the design and conduct of the trial.…”
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    A randomized double-blind placebo-controlled trial to evaluate the value of a single bolus intravenous alfentanil in CT colonography
  4. 1224
    “…This study is supported by the Declaration of Helsinki and subsequent ethical guidelines. RESULTS: A severe reduction in vitro in allergenicity to hazelnut after AC processing was observed in the allergic clinic-patients studied. …”
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    Effects of autoclaving and high pressure on allergenicity of hazelnut proteins
  5. 1225
    “…Methods: Noise levels of nighttime–outdoor traffic were modeled based on the traffic intensities in the cities of Helsinki and Vantaa, Finland. In these cities, 7,019 public sector employees (81% women) responded to postal surveys on sleep and health. …”
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    Associations between Nighttime Traffic Noise and Sleep: The Finnish Public Sector Study
  6. 1226
    por Eronen, Lauri, Toivonen, Hannu
    Publicado 2012
    “…Some of its functionalities are available in a public query interface at http://biomine.cs.helsinki.fi, allowing searching for and visualizing connections between given biological entities.…”
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    Biomine: predicting links between biological entities using network models of heterogeneous databases
  7. 1227
    “…We declared that the research carried out on human (Zhai Yafeng) was in compliance with the Helsinki Declaration, and experimental research on animals also followed internationally recognized guidelines. …”
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    Identification of an intestine-specific promoter and inducible expression of bacterial α-galactosidase in mammalian cells by a lac operon system
  8. 1228
    “…SETTING: School children in Helsinki, Finland. PARTICIPANTS: Two siblings of the index case and 58 classmates exposed to M tuberculosis. …”
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    Evaluation of the filter paper IP-10 tests in school children after exposure to tuberculosis: a prospective cohort study with a 4-year follow-up
  9. 1229
    “…ETHICS AND DISSEMINATION: This study was approved by the local Ethics Committee of The North Denmark Region (N-20110085) and the protocol conforms to the principles of the Declaration of Helsinki. Data collection will be completed by April 2014. …”
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    Efficacy of multimodal, systematic non-surgical treatment of knee osteoarthritis for patients not eligible for a total knee replacement: a study protocol of a randomised controlled trial
  10. 1230
    “…METHODS AND DESIGN: During years 2011 and 2012, a sample of residents in assisted living facilities in Helsinki (approximately 212) will be recruited, having offered to participate in a trial aiming to reduce their harmful drugs. …”
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    Reducing inappropriate, anticholinergic and psychotropic drugs among older residents in assisted living facilities: study protocol for a randomized controlled trial
  11. 1231
    “…METHODS: We carried out cross-sectional analyses of baseline data of 2526 clients who sought treatment for illicit drug use at Helsinki Deaconess Institute between 2001 and 2008. …”
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    Coexisting social conditions and health problems among clients seeking treatment for illicit drug use in Finland: The HUUTI study
  12. 1232
    por Nuutinen, Teija, Ray, Carola, Roos, Eva
    Publicado 2013
    “…METHODS: The school-aged children (n=353, 51% girls) from 27 schools answered a questionnaire in 2006 and again 2008 in the Helsinki region of Finland. Electronic media use was measured by computer use and TV viewing. …”
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    Do computer use, TV viewing, and the presence of the media in the bedroom predict school-aged children’s sleep habits in a longitudinal study?
  13. 1233
    “…Patients scheduled to undergo creation of either brachial or radial arteriovenous fistulae will receive a study information sheet, and consent will be obtained in keeping with the Declaration of Helsinki. Patients will be randomised to receive either: (i) an ultrasound guided brachial plexus block using lignocaine with adrenaline and levobupivicaine, or (ii) local anaesthetic infiltration with lignocaine and levobupivicaine. …”
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    Does regional compared to local anaesthesia influence outcome after arteriovenous fistula creation?
  14. 1234
    “…ETHICS AND DISSEMINATION: The study is being carried out in agreement with the Declaration of Helsinki and the Medical Research Involving Human Subjects Act. …”
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    The COMPlaints After Stroke (COMPAS) study: protocol for a Dutch cohort study on poststroke subjective cognitive complaints
  15. 1235
    “…ETHICS AND DISSEMINATION: CopenHeartSF is approved by the regional ethics committee (no H-4-2012-168) and the Danish Data Protection Agency (no 2007-58-0015) and is performed in accordance with good clinical practice and the Declaration of Helsinki in its latest form. REGISTRATION: Clinicaltrials.gov identifier: NCT01796353.…”
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    The CopenHeartSF trial—comprehensive sexual rehabilitation programme for male patients with implantable cardioverter defibrillator or ischaemic heart disease and impaired sexual function: protocol of a randomised clinical trial
  16. 1236
    “…ETHICS AND DISSEMINATION: AERIS is conducted in accordance with the Declaration of Helsinki and Good Clinical Practice, and has been approved by the institutional ethics and review board. …”
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    Acute Exacerbation and Respiratory InfectionS in COPD (AERIS): protocol for a prospective, observational cohort study
  17. 1237
    “…A total of 13'400 2D images of patients examined routinely in the Clinical Department of Ophthalmology, in District Railway Hospital in Katowice, Poland, were analysed in accordance with the Declaration of Helsinki. A new method has been proposed for the analysis of corneal deflection images in the Corvis tonometer with the use of the Canny edge detection method, mathematical morphology methods and context-free operations. …”
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    Selected parameters of the corneal deformation in the Corvis tonometer
  18. 1238
    “…ETHICS AND DISSEMINATION: The study will be performed and monitored according to the Good Clinical Practice-International Conference on Harmonisation (GCP-ICH) regulations and conducted according to the principles of the Helsinki Declaration. The Danish Medicines Agency, the local Research Ethics Committee and the Danish Data Protection Agency have approved the study. …”
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    A protocol for a randomised, double-blind, placebo-controlled study of the effect of LIraglutide on left VEntricular function in chronic heart failure patients with and without type 2 diabetes (The LIVE Study)
  19. 1239
    “…Contact: samuli.ripatti@helsinki.fi; samuel.kaski@aalto.fi Supplementary information: Supplementary data are available at Bioinformatics online.…”
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    Assessing multivariate gene-metabolome associations with rare variants using Bayesian reduced rank regression
  20. 1240
    “…ETHICS AND DISSEMINATION: The study will be performed in agreement with the Declaration of Helsinki and is approved by the National University of Ireland Galway Research Ethics Committee (12/05/05). …”
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    Comparing the clinical-effectiveness and cost-effectiveness of an internet-delivered Acceptance and Commitment Therapy (ACT) intervention with a waiting list control among adults with chronic pain: study protocol for a randomised controlled trial
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