“…Yet the pathogenesis of hepatitis C during pregnancy and in the neonatal period remains poorly understood. …”
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“…Hepatitis-C-virus- (HCV-) related end-stage cirrhosis is the primary indication for liver transplantation in many countries. …”
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“…An exception is in the treatment for chronic hepatitis C virus (HCV) genotype 1 infection with pegylated interferon α and ribavirin. …”
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“…In this study, we report the case of a patient who contracted the hepatitis C virus after transrectal prostate biopsy as part of an individual screening for prostate cancer.…”
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“…Hepatitis C virus (HCV) is a positive sense, single-stranded RNA virus in the Flaviviridae family. …”
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“…Two direct-acting antivirals (DAAs) against hepatitis C virus (HCV): telaprevir and boceprevir, are now available in combination with peginterferon plus ribavirin for the treatment of chronic hepatitis C infection. …”
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“…Chronic hepatitis C is characterized by metabolic disorders and a microenvironment in the liver dominated by oxidative stress, inflammation and regeneration processes that lead in the long term to hepatocellular carcinoma. …”
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“…Hepatitis C virus (HCV) is a major public health problem. …”
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“…Epidemiological studies have shown an increased occurrence of metabolic disorders such as insulin resistance (IR) and steatosis in patients with hepatitis C virus (HCV) infection. IR is believed to represent one of the central clinical features of the “metabolic syndrome” and the major pathogenetic factor for type 2 diabetes mellitus. …”
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“…The natural history of hepatitis C in the transplant setting is shortened. …”
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“…Hepatitis C virus is considered a major public health problem, infecting 2%–3% of the human population. …”
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“…AIM: The objective of this study was to evaluate the real outcomes of chronic hepatitis C patients, who treated with interferon plus ribavirin (INF-RBV) and peg-interferon plus ribavirin (PEG-RBV). …”
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“…The current standard-of-care treatments for chronic hepatitis C, based on a bitherapy that combines peginterferon alpha-2a or -2b and ribavirin for all genotypes, and on a triple therapy with the addition of an antiprotease specifically for genotype 1, are associated with a limited adherence that decreases their efficacy. …”
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“…Objective. Chronic hepatitis C virus (HCV) infection is a serious health problem in Taiwan. …”
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“…Over 170 million patients worldwide are chronically infected with Hepatitis C virus (HCV); making it a globally important infection. …”
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“…Simeprevir (TMC435, Olysio™), a second-generation hepatitis C virus (HCV) protease inhibitor, has been recently approved for the treatment of genotype 1 chronic hepatitis C in combination with pegylated interferon and ribavirin. …”
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“…Hepatitis C virus (HCV) was identified for the first time more than 20 years ago. …”
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