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2001por Mailly, Laurent, Robinet, Eric, Meuleman, Philip, Baumert, Thomas F., Zeisel, Mirjam B.“…Hepatitis C virus (HCV) is a major cause of cirrhosis and hepatocellular carcinoma (HCC) making the virus the most common cause of liver failure and transplantation. …”
Publicado 2013
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2002por Mori, Kazuyo, Arai, Hirotaka, Abe, Takehiko, Takayama, Hisashi, Toyoda, Mitsuo, Ueno, Takashi, Sato, Ken“…A total of 33 chronic hepatitis C (CHC) patients (median age 68; range 51–84) were enrolled. …”
Publicado 2013
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2003por Patil, Raj, Cotler, Scott J, Banaad-Omiotek, Geraldine, McNutt, Robert A, Brown, Michael D, Cotler, Sheldon, Jensen, Donald M“…BACKGROUND: Physicians' perspectives regarding hepatitis C shape their approach to patient management. …”
Publicado 2001
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2004“…BACKGROUND: While ribavirin mono-therapy regimens have minimal effect on patients with chronic hepatitis C virus (HCV) infections, they can be efficacious when combined with interferon. …”
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2005por Gonzaga, Rosa Maria S., Rodart, Itatiana F., Reis, Mitermayer Galvão, Ramalho Neto, Cícero Eduardo, Silva, Denise Wanderlei“…We determined the frequency of hepatitis C virus (HCV) genotypes in anti-HCV seropositive patients in the state of Alagoas, Brazil, by means of nested-reverse transcription-polymerase chain reaction (RT-nested-PCR) followed by restriction fragment length polymorphism (RFLP) of amplified fragments of the 5´NCR. …”
Publicado 2008
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2006por Zhao, Yuliang, Shen, Liping, Ma, Jingchen, Gao, Zhao, Han, Xu, Qi, Shunxiang, Li, Qi“…BACKGROUND: In 1985, a hepatitis C virus (HCV) outbreak caused by plasmapheresis donation was reported in the Hebei Province, China. …”
Publicado 2013
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2007Alterations in NK Cell Phenotype in Relation to Liver Steatosis in Children with Chronic Hepatitis Cpor Mania, Anna, Kaczmarek, Mariusz, Kemnitz, Paweł, Mozer-Lisewska, Iwona, Sikora, Jan, Figlerowicz, Magdalena, Woźniak, Aldona, Mazur-Melewska, Katarzyna, Służewski, Wojciech, Żeromski, Jan“…NK cells were found to play an important role in liver fibrosis, a process commonly seen in a chronic liver disease such as chronic hepatitis C (CHC). The aim of this study was to evaluate potential differences in relation to coexisting liver steatosis in children with chronic hepatitis C. …”
Publicado 2013
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2008por Salehi Moghadam, Faraz, Mohebbi, Seyed Reza, Hosseini, Seyed Masoud, Damavand, Behzad, Zali, Mohammad Reza“…BACKGROUND: Hepatitis C virus (HCV) is one of the leading causes of chronic liver disease. …”
Publicado 2013
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2009“…INTRODUCTION: Hepatitis C virus (HCV) represents a serious public health concern. …”
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2010“…Although a role of the hepatitis C virus in CWP cannot be deduced by these results, symptomatic improvement via antiviral treatment exists for this subset of patients.…”
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2011por Pécheur, Eve-Isabelle“…The molecular interplay between host factors and invading viruses is a continuous coevolutionary process that determines viral host range and pathogenesis. The hepatitis C virus (HCV) is a strictly human pathogen, causing chronic liver injuries accompanied by lipid disorders. …”
Publicado 2012
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2012“…BACKGROUND/AIMS: Several studies analyzed the association between hepatitis C virus (HCV) infection and the risk of stroke or cerebrovascular death, but their findings were inconsistent. …”
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2013“…More than one and half of current cases of hepatocellular carcinoma in the US, Europe, and Japan are attributable to hepatitis C virus (HCV) infection. HCV is also the primary cause of death in patients with HCV-related cirrhosis, with annual incidences of 0.5%–5% in Europe and 4%–10% in Asia. …”
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2014por Imran, Muhammad, Manzoor, Sobia, Ashraf, Javed, Khalid, Madiha, Tariq, Muqddas, Khaliq, Hafiza Madeha, Azam, Sikandar“…The current standard of care (SOC) for hepatitis C virus (HCV) infection is the combination of pegylated interferon (PEG-IFN), Ribavirin and protease inhibitor for HCV genotype 1. …”
Publicado 2013
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2015“…Inhibitors targeting the hepatitis C virus (HCV) encoded viroporin, p7 prevent virus release in vitro. …”
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2016por Siqueira, E.R.F., Oliveira, C.P.M.S., Correa-Giannella, M.L., Stefano, J.T., Cavaleiro, A.M., Fortes, M.A.H.Z., Muniz, M.T.C., Silva, F.S., Pereira, L.M.M.B., Carrilho, F.J.“…The reduction of hepatic microsomal transfer protein (MTP) activity results in fatty liver, worsening hepatic steatosis and fibrosis in chronic hepatitis C (CHC). The G allele of the MTP gene promoter, -493G/T, has been associated with lower transcriptional activity than the T allele. …”
Publicado 2011
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2017por Shen, Hui, Yamashita, Atsuya, Nakakoshi, Masamichi, Yokoe, Hiromasa, Sudo, Masashi, Kasai, Hirotake, Tanaka, Tomohisa, Fujimoto, Yuusuke, Ikeda, Masanori, Kato, Nobuyuki, Sakamoto, Naoya, Shindo, Hiroko, Maekawa, Shinya, Enomoto, Nobuyuki, Tsubuki, Masayoshi, Moriishi, Kohji“…In this report, we tested the effect of CAPE and its derivatives on hepatitis C virus (HCV) replication in order to develop an effective anti-HCV compound. …”
Publicado 2013
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2018por Cox, Erica Machlin, Sagan, Selena M., Mortimer, Stefanie A.W., Doudna, Jennifer A., Sarnow, Peter“…The hepatitis C viral RNA genome forms a complex with liver-specific microRNA (miR-122) at the extreme 5′ end of the viral RNA. …”
Publicado 2013
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2019“…Hepatitis C virus is the most common chronic blood-borne infection in the USA. …”
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2020por Kim, Jong-Woo, Park, Sang Jin, Lim, Jong Hwan, Yang, Jae Won, Shin, Jung Cheul, Lee, Sang Wook, Suh, Joo Won, Hwang, Soon B.“…Hepatitis C virus (HCV) infection is a major cause of liver disease, including cirrhosis and hepatocellular carcinoma. …”
Publicado 2013
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