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9141por Trecarichi, Enrico Maria, Galli, Jacopo, Tamburrini, Enrica, de Donati, Katleen Gaetano, Scoppettuolo, Giancarlo, Colosimo, Cesare, Pierconti, Francesco, Paludetti, Gaetano, Tumbarello, Mario“…In this case report, the authors describe the first case of ENB in a young adult man who was human immunodeficiency virus (HIV)-1 and Hepatitis C virus (HCV) coinfected. The authors discuss all the aspects of this rare disease, focusing on treatment options and prognosis.…”
Publicado 2011
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9142“…Direct-acting antivirals (DAAs) have significantly improved the treatment of infection with the hepatitis C virus. A promising class of novel antiviral agents targets the HCV NS5A protein. …”
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9143por Renner, Ivonne, Funk, Nancy, Geissler, Rene, Friedrich, Susann, Penzel, Anika, Behrens, Sven-Erik“…Importantly, TALE-mediated IFN-beta signaling occurs independently of pathogen pattern recognition but effectively prohibits viral RNA replication as demonstrated with a hepatitis C virus replicon. TALEs were thus indicated to be valuable tools in various applications addressing, for example, virus-host interactions.…”
Publicado 2014
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9144“…Chronic infection with hepatitis C virus (HCV) affects about 170 million people worldwide and is a major cause of liver complications. …”
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9145por Louten, Jennifer, Beach, Michael, Palermino, Kristina, Weeks, Maria, Holenstein, Gabrielle“…Several human viruses of clinical importance are discussed, namely, herpesviruses, polyomaviruses, hepatitis B virus, hepatitis C virus, human papillomavirus, and human immunodeficiency virus.…”
Publicado 2016
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9146“…With continued drug development and approval of hepatitis C antivirals, research is expected to increase. …”
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9147por Dias, Cátia, Duarte-Ribeiro, Filipa, Pipa, Sara, Barbosa, Ana Rita, Mota, Margarida, Rosas Vieira, Fernando“…The newer oral treatments for chronic hepatitis C virus infection are one of the greatest revolutions in modern medicine. …”
Publicado 2018
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9148por Sandargo, Birthe, Thongbai, Benjarong, Praditya, Dimas, Steinmann, Eike, Stadler, Marc, Surup, Frank“…While most congeners showed moderate antimicrobial and cytotoxic activity, 4-hydroxypleurogrisein emerged as an inhibitor of hepatitis C virus infectivity in mammalian liver cells.…”
Publicado 2018
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9149“…A class of dihydropyranobenzimidazole inhibitors was recently discovered that acts against the hepatitis C virus (HCV) in a new way, binding to the IRES-IIa subdomain of the highly conserved 5' untranslated region of the viral RNA and thus preventing the ribosome from initiating translation. …”
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9150“…Hepatitis C infection is the leading cause of liver diseases worldwide and a major health concern that affects an estimated 3% of the global population. …”
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9151“…We describe stabilizable polypeptide linkages (StaPLs) based on hepatitis C virus protease. StaPLs undergo autoproteolysis to cleave proteins by default, while protease inhibitors prevent cleavage and preserve protein function. …”
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9152“…Mixed cryoglobulinemia (MC) is well known for its association with chronic hepatitis C virus (HCV) infection. However, it has also been linked to autoimmune disorders and hematological malignancies, particularly of B-cell lymphoid origin. …”
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9153“…Recombinant IFN-α is now used as the basis for treatment of chronic hepatitis C virus infection and can also be used to treat certain forms of chronic hepatitis B virus infections. …”
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9154por Larsen, Reinhard“…Aufgrund der Spenderauswahl und des Screenings sind die Blutpräparate virussicher; die Übertragung von HIV und Hepatitis-C-Viren beschränkt sich auf Einzelfälle. Dennoch gibt es nach wie vor teils schwerwiegende Transfusionsrisiken, sodass beim Einsatz von Erythrozytenkonzentraten, Plasma und Gerinnungspräparaten ein besonders sorgfältiges und umsichtiges Vorgehen erforderlich ist.…”
Publicado 2016
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9155“…Cryoglobulinemic vasculitis is most commonly observed in the setting of hepatitis C infection. However, many other etiologies have been identified as well. …”
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9156por Mrabet, Soumaya, Zaghouani, Houneida, Mestiri, Sarra, Akkari, Imen, Ben Jazia, Elhem“…The subtype of diffuse large B-cell lymphoma (DLBCL) is more infrequent. In contrast to hepatitis C virus, the association between hepatitis B virus and lymphoma is less clear. …”
Publicado 2020
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9157por Bhattacharjee, Chayan, Singh, Maitri, Das, Debisukti, Chaudhuri, Sujit, Mukhopadhyay, Aparna“…Hepatitis C is a positive stranded enveloped RNA virus belonging to the Flaviviridae family. …”
Publicado 2021
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9158Towards a Systems Immunology Approach to Understanding Correlates of Protective Immunity against HCVpor Shoukry, Naglaa H.“…These approaches that integrate multiple facets of the immune response, including transcriptomics, serology and immune functions, are now being applied to understand correlates of protective immunity against hepatitis C virus (HCV) infection and to inform vaccine development. …”
Publicado 2021
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9159“…Vaccination is a key intervention for the elimination of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections to fulfil the WHO’s 2030 global elimination goal. …”
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9160por Barr, Peter B., Bigdeli, Tim B., Meyers, Jacquelyn L., Peterson, Roseann E., Sanchez-Roige, Sandra, Mallard, Travis T., Dick, Danielle M., Paige Harden, K., Wilkinson, Anna, Graham, David P., Nielsen, David A., Swann, Alan, Lipsky, Rachele K., Kosten, Thomas, Aslan, Mihaela, Harvey, Philip D., Kimbrel, Nathan A., Beckham, Jean C.“…Effect sizes ranged from OR = 1.02 (95% CI = 1.01, 1.03) for overweight/obesity to OR = 1.44 (95% CI = 1.42, 1.47) for viral hepatitis C. Of the significant outcomes 73 (11.9%) and 26 (4.5%) were significant in the African and Hispanic/Latin American results, respectively. …”
Publicado 2023
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