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10101“…As the initial atomic coordinates, we use cryoelectron microscopy data for the apo form of RdRp of the SARS-CoV-2 virus and data on the structure of RdRp of the hepatitis C virus. After appropriate substitutions, an RdRp complex containing RNA chains and a potential enzyme inhibitor, favipiravir in the form of ribosatriphosphate, are constructed. …”
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10102“…Hepatitis B insertional mutagenesis modifies the function of cancer driver genes and could promote chromosomal instability. In contrast, hepatitis C virus promotes hepatocellular carcinoma (HCC) occurrence mainly through cirrhosis development whereas the direct oncogenic role of the virus in human remains debated. …”
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10103por Muzaffar, Samreen, Ahmed, Najeeb, Rahman, Uzma, Al Kandari, Fareeda, Usmani, Sharjeel“…We report a case of a 45-year-old man with known colorectal cancer, cirrhosis, and hepatitis C. Contrast-enhanced computed tomography (CT) showed a hypervascular lesion in the liver, and (18)F-fluorodeoxyglucose positron emission tomography (PET) did not show any suspicious hepatic uptake. (68)Ga-PSMA PET-CT showed predominantly heterogeneous perilesional uptake in a configuration similar to the arterial enhancement pattern on the diagnostic CT. (68)Ga-PSMA uptake in hepatocellular carcinoma appears to be primarily neoangiogenesis driven, and its morphological and functional characterization can subsequently influence the selection of anti-neoangiogenic chemotherapy agents as well as guiding radionuclide ligand therapy.…”
Publicado 2021
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10104“…Potential virally encoded selenoproteins have been identified by computational analysis in different viral genomes like HIV-1, Japanese encephalitis virus (JEV), and hepatitis C virus. This review discusses the role and the possible mechanisms of selenium, selenoproteins, and virally encoded selenoproteins in the pathogenicity of viral infections. …”
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10105“…Additionally, the association of hepatitis C and hepatitis B infection was observed in oral cavity, oropharyngeal, laryngeal, and nasopharyngeal cancers. …”
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10106por Nicastro, Emanuele, Norsa, Lorenzo, Di Giorgio, Angelo, Indolfi, Giuseppe, D'Antiga, Lorenzo“…Chronic infections by hepatitis B virus (HBV) and hepatitis C virus (HCV) major causes of advanced liver disease and mortality worldwide. …”
Publicado 2021
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10107“…The European and Japanese liver societies elected to confine recommendations for HCC screening to noncirrhotic patients with advanced fibrosis due to hepatitis C or hepatitis B only. These latter recommendations, however, are challenged by the increasing number of patients with viral hepatitis in whom HCC risk has been attenuated but not eradicated by successful antiviral therapy. …”
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10108por Zadroga, John A., Mogulla, Vanajakshi, Grant, Christopher, Jevtic, Djordje, Virata, Andrew, Dumic, Igor“…The patient's medical history was notable for untreated hepatitis C infection and end-stage renal disease, requiring hemodialysis three times a week. …”
Publicado 2021
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10109por Durso-Cain, Karina, Kumberger, Peter, Schälte, Yannik, Fink, Theresa, Dahari, Harel, Hasenauer, Jan, Uprichard, Susan L., Graw, Frederik“…The hepatitis C virus (HCV) is capable of spreading within a host by two different transmission modes: cell-free and cell-to-cell. …”
Publicado 2021
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10110por Chahal, Jasmin, Gebert, Luca F. R., Camargo, Carolina, MacRae, Ian J., Sagan, Selena M.“…Hepatitis C virus (HCV) is a positive-sense RNA virus that interacts with a liver-specific microRNA called miR-122. miR-122 binds to two sites in the 5′ untranslated region of the viral genome and promotes HCV RNA accumulation. …”
Publicado 2021
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10111por Yu, Shicheng, Wang, Qiqi, Wang, Shujun, Zhang, Jiaojiao, Hu, Yuehua, Li, Junqi, Long, Xiaojuan, Xiang, Xianglong, Zhou, Maigeng, Tan, Feng“…In China, the percent changes in years lived with disability (YLDs) due to acute hepatitis A, B, and E in groups aged 50–69 years and 70 years or more and in all age groups for acute hepatitis C were increased from 2000 to 2019. What are the implications for public health practices? …”
Publicado 2020
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10112por Zhang, Xinhe, Guan, Lin, Tian, Haoyu, Zeng, Zilu, Chen, Jiayu, Huang, Die, Sun, Ji, Guo, Jiaqi, Cui, Huipeng, Li, Yiling“…Hepatitis B virus (HBV) infection and hepatitis C virus (HCV) infection are important causes of HCC. …”
Publicado 2021
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10113por Malandris, Konstantinos, Kalopitas, Georgios, Theocharidou, Eleni, Germanidis, Georgios“…The approval of combination therapies with direct-acting antiviral (DAA) regimens has led to significant progress in the field of hepatitis C virus (HCV) treatment. Although most patients treated with these agents achieve a virological cure, resistance to DAAs is a major issue. …”
Publicado 2021
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10114“…The cationic proinflammatory cytokine Interleukin 26 (IL-26) shows antibacterial activity and inhibits the replication of cytomegalovirus and hepatitis C virus. This study evaluates the early microbicidal activities of IL-26 against major bacterial species including multi-resistant variants and Candida albicans. …”
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10115por Olivares-Hernández, Alejandro, Figuero-Pérez, Luis, Miramontes-González, José Pablo, López-Gutiérrez, Álvaro, González-Sarmiento, Rogelio, Cruz-Hernández, Juan Jesús, Fonseca-Sánchez, Emilio“…Certain causal relationships, such as that between the Epstein–Barr virus (EBV) in nasopharyngeal cancer or hepatitis C and B viruses in hepatocarcinoma, have been clearly established, and their implications for the prognosis and treatment of solid tumours are currently unknown. …”
Publicado 2021
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10116“…In this context, our attention is focused on novel compounds acting on nuclear receptors, whose activity could be beneficial in viral infections, including coronavirus, hepatitis C virus, and cytomegalovirus. ABSTRACT: The manipulation of host metabolisms by viral infections has been demonstrated by several studies, with a marked influence on the synthesis and utilization of glucose, nucleotides, fatty acids, and amino acids. …”
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10117por Zahidin, Muhamad Aidil, Mohd Noor, Noor Haslina, Johan, Muhammad Farid, Abdullah, Abu Dzarr, Zulkafli, Zefarina, Edinur, Hisham Atan“…This review revealed that sITP in Malaysia is commonly associated with autoimmune diseases (Evan’s syndrome, SLE and WAS), malignancy (Kaposi’s sarcoma and breast cancer) and infection (dengue haemorrhagic fever, Helicobacter pylori and hepatitis C virus). The relationship between ITP and autoimmune diseases, malignancy and infections raise the question concerning the mechanism involved in these associations. …”
Publicado 2021
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10118por Rajewski, Paweł, Zarębska-Michaluk, Dorota, Janczewska, Ewa, Gietka, Andrzej, Mazur, Włodzimierz, Tudrujek-Zdunek, Magdalena, Tomasiewicz, Krzysztof, Belica-Wdowik, Teresa, Baka-Ćwierz, Barbara, Dybowska, Dorota, Halota, Waldemar, Lorenc, Beata, Sitko, Marek, Garlicki, Aleksander, Berak, Hanna, Horban, Andrzej, Orłowska, Iwona, Simon, Krzysztof, Socha, Łukasz, Wawrzynowicz-Syczewska, Marta, Jaroszewicz, Jerzy, Deroń, Zbigniew, Czauż-Andrzejuk, Agnieszka, Citko, Jolanta, Krygier, Rafał, Piekarska, Anna, Laurans, Łukasz, Dobracki, Witold, Białkowska, Jolanta, Tronina, Olga, Wietlicka-Piszcz, Magdalena, Pawłowska, Małgorzata, Flisiak, Robert“…The results indicate that the hepatitis C infection seems to be a risk factor for diabetes in persons with more advanced liver fibrosis, for older people, and for the male gender. …”
Publicado 2022
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10119“…Also, we argued about the role of this cytokine in viral infections including hepatitis B (HBV), hepatitis C (HCV), influenza (Flu), and COVID-19. Also, it illustrated the IL-38 protective effects on sepsis. …”
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10120por Gómez Delgado, Irene, Gutiérrez-Tenorio, Josué, Fraga Rodríguez, Gloria M, Cavero, Teresa, Arjona, Emilia, Sánchez-Corral, Pilar“…We report on a 66-year-old male with chronic hepatitis C virus (HCV) infection and a combined liver–kidney transplant that was diagnosed with MPGN at the age of 63 years and a 5-year-old boy who presented with aHUS at the age of 21 months following a Streptococcus pneumoniae infection. …”
Publicado 2020
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