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10241“…These viruses include human papillomavirus (HPV), Epstein–Barr virus (EBV), Merkel cell polyomavirus (MCV), human T-cell leukemia virus 1 (HTLV-1), Kaposi's sarcoma-associated herpesvirus (KSHV), hepatitis C virus (HCV) and hepatitis B virus (HBV). …”
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10242“…In addition to common types of viral hepatitis, ie, hepatitis A, hepatitis B, and hepatitis C viruses, Epstein-Barr virus (EBV) may result in hepatitis in some cases. …”
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10243“…Persistent infections with human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV) are a major cause of morbidity and mortality worldwide. …”
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10244“…However, long-term kidney toxicity is now acknowledged as a modest but significant risk for tenofovir-containing regimens, and continuous use of tenofovir in HIV therapy is currently under question by practitioners and researchers. Co-morbidities (hepatitis C, diabetes), low body weight, older age, concomitant administration of potentially nephrotoxic drugs, low CD4 count, and duration of therapy are all risk factors associated with tenofovir-associated tubular dysfunction. …”
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10245“…Even in the era of successful combination antiretroviral therapy (cART), co-infection of Hepatitis C virus (HCV) remains one of the leading causes of non-AIDS-related mortality and morbidity among HIV-positive individuals as a consequence of accelerated liver fibrosis and end-stage liver disease (ESLD). …”
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10246por Flynn, Ryan A., Martin, Lance, Spitale, Robert C., Do, Brian T., Sagan, Selena M., Zarnegar, Brian, Qu, Kun, Khavari, Paul A., Quake, Stephen R., Sarnow, Peter, Chang, Howard Y.“…FAST-iCLIP of PCBP2 in hepatitis C virus-infected cells enabled a joint analysis of the PCBP2 interactome with host and viral RNAs and their interplay. …”
Publicado 2015
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10247por Tsuda, Shawn“…The patient had multiple comorbidities, including obesity, hepatitis C, endocarditis secondary to IV drug use, tobacco smoking, bilateral inguinal hernia, and recurrent umbilical hernia. …”
Publicado 2014
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10248“…Post-transplant antiviral therapy for hepatitis C virus infection is generally reserved for patients showing progressive disease. …”
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10249por Wongtrakul, Jeerang, Thongtan, Thananya, Roytrakul, Sittiruk, Kumrapich, Benjawan, Janphen, Kanokwan, Praparattanapan, Jutarat, Supparatpinyo, Khuanchai, Smith, Duncan R.“…However, one of the main concerns with the use of NVP is hepatotoxicity and elevation of liver enzymes as a consequence of highly active antiretroviral therapy (HAART) containing NVP is more often reported in HIV patients coinfected with hepatitis C virus than in HIV-monoinfected patients. …”
Publicado 2014
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10250por Barsoum, Rashad S.“…These classes have been linked to respective clinical manifestations and depend on the stage of evolution of the host’s immune response, extent of associated hepatic fibrosis and co-infection with salmonella or hepatitis C. Secondary amyloidosis develops in 15% of such patients, representing a critical impairment of macrophage function. …”
Publicado 2013
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10251“…Autoantibodies targeting these relatively unknown structures have been almost exclusively observed in hepatitis C virus (HCV) patients who have undergone treatment with pegylated interferon-α/ribavirin (IFN/RBV) combination therapy. …”
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10252por Sugita, Tomonori, Amano, Katsushi, Nakano, Masanori, Masubuchi, Noriko, Sugihara, Masahiro, Matsuura, Tomokazu“…A total of 150 subjects, including patients with hepatitis C virus (HCV) (n = 44), hepatitis B virus (HBV) (n = 23), alcoholic liver disease (ALD) (n = 21), biliary tract disease (n = 20), nonalcoholic fatty liver disease (NAFLD) (n = 13), and other liver diseases (n = 29), were recruited. …”
Publicado 2015
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10253“…Finally, the recently approved combination treatments for chronic hepatitis C containing direct-acting antivirals may definitely change the treatment protocols in the future although there is no experience with these drugs in dually infected patients until today.…”
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10254“…Hepatotropic viruses such as hepatitis B virus (HBV) and hepatitis C virus (HCV) are the major etiological agents associated with development of hepatocellular carcinoma (HCC). …”
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10255“…Hepatitis C virus (HCV) induces autophagy to enhance its replication. …”
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10256por Kwon, Hyock Joo, Xing, Weimei, Chan, Katie, Niedziela-Majka, Anita, Brendza, Katherine M., Kirschberg, Thorsten, Kato, Darryl, Link, John O., Cheng, Guofeng, Liu, Xiaohong, Sakowicz, Roman“…Ledipasvir, a direct acting antiviral agent (DAA) targeting the Hepatitis C Virus NS5A protein, exhibits picomolar activity in replicon cells. …”
Publicado 2015
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10257“…The effectiveness of this protocol was first evaluated with 1,762 coupled serum/DBS pairs for detecting markers of hepatitis B virus, hepatitis C virus, and human immunodeficiency virus infections on an automated analytical platform. …”
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10258“…Chronic hepatitis C virus (HCV) infection represents a global health problem that affects up to 130–150 million people worldwide. …”
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10259“…A modified method which can be used for the rapid screening of mutations in the protein kinase R-binding domain (PKR-BD) region and the hypervariable region 1 (HVR1) of hepatitis C virus (HCV) is described. This method is based on a high-resolution melting (HRM) technique used for genotyping single nucleotide polymorphisms and allows the detection of single nucleotide substitutions in the DNA sequence by measuring its T(m). …”
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10260“…As IRES-mediated translation is regulated differently from cap-dependent translation under various cellular conditions, we sought to investigate whether temperature influences efficiency of viral IRES-mediated translation initiation by using bicistronic reporter constructs containing an IRES element of encephalomyocarditis virus (EMCV), foot-and-mouth disease virus (FMDV), hepatitis C virus (HCV), human rhinovirus (HRV) or poliovirus (PV). …”
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