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10281por Bean, Madelyne, Tang, Lydia, Kottilil, Shyam, Beavers, Kimberly L., Meissner, Eric G.“…Eradication of chronic hepatitis C virus (HCV) infection is now possible with all oral antiviral medications, including the combination of ombitasvir, paritaprevir, dasabuvir, and ritonavir (PrOD) with or without ribavirin. …”
Publicado 2016
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10282por Bernieh, Bassam“…Hepatitis delta virus is a defective virus that can only infect HBV-positive individuals. Hepatitis C virus (HCV) is the most significant cause of non-A, non-B hepatitis and is mainly transmitted by blood transfusion. …”
Publicado 2015
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10283por Ahmad, Irshad“…OBJECTIVES: To study the prevalence of hepatitis B (HBV) and hepatitis C (HCV) viral infections among pregnant women in the Peshawar district of Pakistan. …”
Publicado 2016
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10284por Babaylova, Elena S., Malygin, Alexey A., Lomzov, Alexander A., Pyshnyi, Dmitrii V., Yulikov, Maxim, Jeschke, Gunnar, Krumkacheva, Olesya A., Fedin, Matvey V., Karpova, Galina G., Bagryanskaya, Elena G.“…We succeeded to spin-label Hepatitis C Virus RNA internal ribosome entry site consisting of ≈330 nucleotides and having a complicated spatial structure. …”
Publicado 2016
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10285por Ahmed-Belkacem, Abdelhakim, Colliandre, Lionel, Ahnou, Nazim, Nevers, Quentin, Gelin, Muriel, Bessin, Yannick, Brillet, Rozenn, Cala, Olivier, Douguet, Dominique, Bourguet, William, Krimm, Isabelle, Pawlotsky, Jean-Michel, Guichou, Jean- François“…Here we use a fragment-based drug discovery approach using nucleic magnetic resonance, X-ray crystallography and structure-based compound optimization to generate a new family of non-peptidic, small-molecule cyclophilin inhibitors with potent in vitro PPIase inhibitory activity and antiviral activity against hepatitis C virus, human immunodeficiency virus and coronaviruses. …”
Publicado 2016
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10286por Sasaki, Reina, Kanda, Tatsuo, Ohtsuka, Masayuki, Yasui, Shin, Haga, Yuki, Nakamura, Masato, Yokoyama, Masayuki, Wu, Shuang, Nakamoto, Shingo, Arai, Makoto, Maruyama, Hitoshi, Miyazaki, Masaru, Yokosuka, Osamu“…Direct-acting antivirals (DAAs) are relatively safe and highly effective for the eradication of hepatitis C virus (HCV) in liver transplant recipients. …”
Publicado 2016
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10287por Smolders, E. J., de Kanter, C. T. M. M., de Knegt, R. J., van der Valk, M., Drenth, J. P. H., Burger, D. M.“…Treatment options for chronic hepatitis C virus (HCV) infection have drastically changed since the development and licensing of new potent direct-acting antivirals (DAAs). …”
Publicado 2016
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10288por Barnes, Richard F. W., Cramer, Thomas J., Sait, Afrah S., Kruse-Jarres, Rebecca, Quon, Doris V. K., von Drygalski, Annette“…Differences between PWH and NHANES persisted after adjusting for age and risk factors (body mass index, renal function, cholesterol, smoking, diabetes, Hepatitis C, and race). Conclusions. Systolic and diastolic BP are higher in PWH than in the general male population and especially among PWH < 30 years old. …”
Publicado 2016
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10289“…BACKGROUND: Direct antiviral agent (DAA) has been the standard of care for patients with hepatitis C virus (HCV) infection. Twelve weeks of paritaprevir/ritonavir/ombitasvir plus dasabuvir (PROD) with or without ribavirin has shown to have a sustained virological response at post-treatment 12 weeks (SVR12) rate of >90% in HCV genotype 1 (HCV-1) patients. …”
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10290“…Griffithsin (GRFT) is a red alga-derived lectin with demonstrated broad spectrum antiviral activity against enveloped viruses, including severe acute respiratory syndrome–Coronavirus (SARS-CoV), Japanese encephalitis virus (JEV), hepatitis C virus (HCV), and herpes simplex virus-2 (HSV-2). …”
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10291por Cate, Jamie H. D.“…Some RNA viruses such as the hepatitis C virus use highly structured RNA elements termed internal ribosome entry sites (IRESs) that commandeer eukaryotic translation initiation, by using specific interactions with the general eukaryotic translation initiation factor eIF3. …”
Publicado 2017
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10292por Mammas, Ioannis N., Theodoridou, Maria, Kramvis, Anna, Thiagarajan, Prakash, Gardner, Sharryn, Papaioannou, Georgia, Melidou, Angeliki, Koutsaki, Maria, Kostagianni, Georgia, Achtsidis, Vassilis, Koutsaftiki, Chryssie, Calachanis, Marcos, Zaravinos, Apostolos, Greenough, Anne, Spandidos, Demetrios A.“…Emphasis was given to HIV-1 management in Greece, a country under continuous financial crisis, hepatitis B vaccination in Africa, treatment options for hepatitis C virus in childhood, Zika virus in pregnancy and infancy, the burden of influenza on childhood, hand-foot-mouth disease and myocarditis associated with Coxsackie viruses. …”
Publicado 2017
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10293por Feng, Wendu, Yu, Decai, Li, Binghua, Luo, Ou-yang, Xu, Tiancheng, Cao, Yajuan, Ding, Yitao“…Patients included had either HCC alone or in conjunction with either pre-existing hepatitis B virus (HBV) or hepatitis C virus (HCV) infection. PCR-based assay incorporating primers to the telomeric hexamer repeats to polymerize and detect telomeric DNA was used. …”
Publicado 2017
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10294“…Less common congenital bleeding disorders include the following deficiencies: Factor I (fibrinogen), Factor II (prothrombin), Factor V, Factor VII, Factor X, Factor XI and Factor XIII, which affect 1953 patients. Hepatitis C Virus (HCV) infection affects 1561 patients, more than 200 of whom have two infections (HCV + HIV). …”
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10295por Zhao, Baoyu, Yi, Guanghui, Du, Fenglei, Chuang, Yin-Chih, Vaughan, Robert C., Sankaran, Banumathi, Kao, C. Cheng, Li, Pingwei“…Key residues in the polymerase are located in similar positions to those of the initiation complex for the hepatitis C virus polymerase. The polymerase conformation is affected by the methyltransferase, which enables a more efficiently elongation of RNA synthesis in vitro. …”
Publicado 2017
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10296“…IDO up-regulation induces immunosuppression and may enhance the risk of hepatitis C virus and hepatitis B virus induced HCC. …”
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10297por Akbari, Morteza, Akbari, Maryam, Naghibzadeh-Tahami, Ahmad, Joulaei, Hassan, Nasiriyan, Maryam, Hesampour, Maryam, Bagheri-Lankarani, Kamran“…BACKGROUND: Worldwide, prisoners are more at risk of being infected by human immunodeficiency virus (HIV) as well as hepatitis C and B in comparison with other risk groups. …”
Publicado 2016
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10298“…RESULTS: In-vitro testing of the new compounds on hepatitis-C virus (HCV) replication in hepatocellular carcinoma cell line HepG2 infected with the virus utilizing the reverse transcription polymerase chain reaction technique (RT-PCR) generally showed inhibition of the replication of HCV RNA (–) strands at low concentration, while, eight compounds; 3a, 6, 7a, 7b, 9a, 9b, 10a and 11b proved to inhibit the replication of HCV RNA (+) and (–) strands at very low concentration range 0.08-0.36 μg/mL. …”
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10299por Sakamaki, Akira, Watanabe, Takayuki, Abe, Satoshi, Kamimura, Kenya, Tsuchiya, Atsunori, Takamura, Masaaki, Kawai, Hirokazu, Yamagiwa, Satoshi, Terai, Shuji“…A 56-year-old Japanese man with liver cirrhosis (LC) due to hepatitis C virus was admitted to our hospital for radiofrequency ablation of residual tumor following lusutrombopag administration. …”
Publicado 2017
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10300“…Subsequently, we reanalyze HIV-1 sequence data from Central Africa and Hepatitis C virus (HCV) data from Egypt. CONCLUSIONS: The new method provides a Bayesian procedure for non-parametric estimation of the demographic history. …”
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