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10321“…Major causative agent for AVH among hepatitis positive patients were hepatitis E virus (HEV) in 36 (69.2%), followed by hepatitis A virus (HAV) 8 (15.3%), hepatitis B virus (HBV) 7 (13.4%) and hepatitis C virus (HCV) 1 (1.9%). The 158 (75.3%) patient were negative for all hepatitis viral markers. …”
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10322por Gregori, Josep, Soria, María Eugenia, Gallego, Isabel, Guerrero-Murillo, Mercedes, Esteban, Juan Ignacio, Quer, Josep, Perales, Celia, Domingo, Esteban“…We have introduced a new diversity index, the rare haplotype load (RHL), to describe NS5B (polymerase) mutant spectra of hepatitis C virus (HCV) populations passaged in absence or presence of the mutagenic agents favipiravir or ribavirin. …”
Publicado 2018
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10323por Luxenburger, Hendrik, Neumann-Haefelin, Christoph, Thimme, Robert, Boettler, Tobias“…Hepatitis C virus (HCV)-specific T cell responses are closely linked to the clinical course of infection. …”
Publicado 2018
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10324por Underwood, Alexander P., Walker, Melanie R., Brasher, Nicholas A., Eltahla, Auda A., Maher, Lisa, Luciani, Fabio, Lloyd, Andrew R., Bull, Rowena A.“…Despite recent advances in curative therapy, hepatitis C virus (HCV) still remains a global threat. …”
Publicado 2018
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10325“…It is expected that in the near future, more liver grafts will be available for patients with HCC due to the implementation of new direct antivirals against hepatitis C, leaving a prone scenario to consider expanding Milan criteria. …”
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10326por Zangeneh, Mehrangiz, Sedaghat Jou, Maryam, Sadighi Gilani, Mohammad Ali, Jamshidi Makiani, Mahin, Sadeghinia, Shaghayegh, Salman Yazdi, Reza“…OBJECTIVE: The present study was performed to assess the prevalence of hepatitis B virus (HBV), hepatitis C virus (HCV) and HIV infections among infertile couples referring to infertility clinic of Royan Institute. …”
Publicado 2018
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10327“…The current article highlights an important association between HP infection and a range of hepatobiliary disorders such as biliary lithiasis (where even an etiological role is involved), cholestatic syndromes (primary sclerosing cholangitis and primary biliary cholangitis), chronic hepatitis B virus, chronic hepatitis C virus, with an evolution towards cirrhosis and hepatocellular carcinoma.…”
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10328“…Although treatment with antiretroviral therapy has extended the life expectancy of people with HIV, liver disease induced by hepatitis B virus (HBV) and hepatitis C virus (HCV) causes significant numbers of non-acquired immune deficiency syndrome (AIDS)-related deaths in co-infected patients. …”
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10329por El Kalamouni, Chaker, Frumence, Etienne, Bos, Sandra, Turpin, Jonathan, Nativel, Brice, Harrabi, Wissal, Wilkinson, David A., Meilhac, Olivier, Gadea, Gilles, Desprès, Philippe, Krejbich-Trotot, Pascale, Viranaïcken, Wildriss“…HO-1 exerts antiviral activity against a broad range of viruses, including the Hepatitis C virus, the human immunodeficiency virus, and the dengue virus by inhibiting viral growth. …”
Publicado 2018
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10330por Milosevic, Ivana, Vujovic, Ankica, Barac, Aleksandra, Djelic, Marina, Korac, Milos, Radovanovic Spurnic, Aleksandra, Gmizic, Ivana, Stevanovic, Olja, Djordjevic, Vladimir, Lekic, Nebojsa, Russo, Edda, Amedei, Amedeo“…In this way, gut-dysbiosis and composition of “ancient” microbiota could be linked to pathogenesis of numerous chronic liver diseases such as chronic hepatitis B (CHB), chronic hepatitis C (CHC), alcoholic liver disease (ALD), non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), development of liver cirrhosis, and hepatocellular carcinoma (HCC). …”
Publicado 2019
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10331“…Hepatitis C virus (HCV) and human immunodeficiency virus (HIV) co-infection among persons who inject drugs (PWID) is a major public health concern. …”
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10332por Caro, L, de Hoon, J, Depré, M, Cilissen, C, Miller, J, Gao, W, Panebianco, D, Guo, Z, Troemel, SL, Anderson, MS, Uemura, N, Butterton, J, Wagner, J, Wright, DH“…Vaniprevir is an inhibitor of the hepatitis C virus (HCV) NS3/4A protease. The aim of these double‐blind, placebo‐controlled phase I studies was to evaluate the safety and pharmacokinetics of vaniprevir in healthy male volunteers. …”
Publicado 2017
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10333por Chang, Kyeong-Ok, Kim, Yunjeong, Lovell, Scott, Rathnayake, Athri D., Groutas, William C.“…There are numerous examples of successful drug development targeting cellular and viral proteases, including antivirals against human immunodeficiency virus and hepatitis C virus. Most FDA-approved antiviral agents are peptidomimetics and macrocyclic compounds that interact with the active site of a targeted protease. …”
Publicado 2019
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10334por Summers, Nathan A., Gharbin, John, Friedman-Moraco, Rachel, Lyon, G. Marshall, Lutgring, Joseph“…CASE PRESENTATION: A 65–75-year-old patient with a history of an orthotopic liver transplant for hepatitis C infection and diabetes was re-admitted to the hospital with abdominal pain and fever. …”
Publicado 2018
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10335Hepatocellular carcinoma after direct-acting antivirals: an unresolved problem. Review of five cases“…MATERIAL AND METHODS: The inclusion criterion was confirmation of successful DAA treatment prior to HCC among hepatitis C virus (HCV)-infected patients with liver cirrhosis. …”
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10336por Mosca, Tainá, Arcuri, Simone Sanches, Miorin, Luiz Antônio, Cristiano, Andrelita de Oliveira, Sens, Yvoty Alves dos Santos, Forte, Wilma Carvalho Neves“…The aim of the present study was to determine the presence of serum cryoglobulins over time in the dialysis treatment in patients with CKD not infected with hepatitis C virus (HCV). Method: Peripheral blood samples were collected at the beginning of dialysis treatment and at 30, 60, 90 and 120 days afterwards. …”
Publicado 2017
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10337por Basyte-Bacevice, Viktorija, Skieceviciene, Jurgita, Valantiene, Irena, Sumskiene, Jolanta, Petrenkiene, Vitalija, Kondrackiene, Jurate, Petrauskas, Dalius, Lammert, Frank, Kupcinskas, Juozas“…Overall, TM6SF2 rs58542926 as well as MBOAT7 rs641738 were not linked to hepatic fibrosis, alcohol or hepatitis C virus induced liver cirrhosis in an Eastern European population. …”
Publicado 2019
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10338por Ohuchi, Masakazu, Inaki, Noriyuki, Nagakari, Kunihiko, Kohama, Shintaro, Sakamoto, Kazuhiro, Ishizaki, Yoichi“…A 79-year-old male undergoing treatment for Child–Pugh B hepatitis C-induced liver cirrhosis and hepatocellular carcinoma complicated with bilateral inguinal hernia underwent transabdominal preperitoneal (TAPP) repair. …”
Publicado 2019
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10339“…Miravirsen (produced by Roche/Santaris) and RG-101 (produced by Regulus Therapeutics), designed to treat hepatitis C, are considered the flagship products of this class of future drugs. …”
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10340“…Consequently, zinc status is a critical factor that can influence antiviral immunity, particularly as zinc-deficient populations are often most at risk of acquiring viral infections such as HIV or hepatitis C virus. This review summarizes current basic science and clinical evidence examining zinc as a direct antiviral, as well as a stimulant of antiviral immunity. …”
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