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1042por Sbarigia, Urbano, Denee, Tom R, Turner, Norris G, Wan, George J, Morrison, Alan, Kaufman, Anna S, Rice, Gary, Dusheiko, Geoffrey M“…Hepatitis C virus infection is one of the main causes of chronic liver disease worldwide. …”
Publicado 2016
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1043“…Purpose: We report a case of retinopathy and uveitis associated with sofosbuvir therapy for hepatitis C infection. Methods: Case report. Results: A 57-year-old-male developed ocular inflammation and retinopathy four weeks after the administration of sofosbuvir for a hepatitis C infection. …”
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1044por Narayanan, Sowmya, Nieh, Albert H., Kenwood, Brandon M., Davis, Christine A., Tosello-Trampont, Annie-Carole, Elich, Tedd D., Breazeale, Steven D., Ward, Eric, Anderson, Richard J., Caldwell, Stephen H., Hoehn, Kyle L., Hahn, Young S.“…Hepatitis C is a chronic liver disease that contributes to progressive metabolic dysfunction. …”
Publicado 2016
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1045“…This study analyzed the risk of clinical trial failure of new drugs for hepatitis C between January 1998 and January 2015. Methods. …”
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1046por Felmlee, Daniel J., Coilly, Audrey, Chung, Raymond T., Samuel, Didier, Baumert, Thomas F.“…Hepatitis C virus (HCV) infection is a leading cause of end-stage liver disease that necessitates liver transplantation. …”
Publicado 2016
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1047“…Hepatitis C virus (HCV) infection affects as many as 185 million people globally, many of whom are chronically infected and progress over time to cirrhosis, decompensated liver disease, hepatocellular carcinoma, and eventually death without a liver transplant. …”
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1048“…While addition of the first-approved protease inhibitors (PIs), telaprevir and boceprevir, to pegylated interferon (PEG-IFN) and ribavirin (RBV) combination therapy significantly increased sustained virologic response (SVR) rates, PI-based triple therapy for the treatment of chronic hepatitis C virus (HCV) infection was prone to the emergence of resistant viral variants. …”
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1049por Misselwitz, Benjamin, Epprecht, Jana, Mertens, Joachim, Biedermann, Luc, Scharl, Michael, Haralambieva, Eugenia, Lutterotti, Andreas, Weber, Konrad P., Müllhaupt, Beat, Chaloupka, Karla“…Hepatitis C is frequently accompanied by immune-related extrahepatic manifestations affecting the skin, kidneys, central and peripheral nervous system and exocrine glands. …”
Publicado 2016
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1050“…OBJECTIVES: : Novel treatments for hepatitis C demonstrate high cure rates, but current high prices can be a barrier to rapid global treatment scale-up. …”
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1051por Thorne, Claire, Indolfi, Giuseppe, Turkova, Anna, Giaquinto, Carlo, Nastouli, Eleni“…Hepatitis C virus infection is a leading cause of liver-related morbidity and mortality. …”
Publicado 2015
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1052
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1053“…Concomitantly he was found to be infected with hepatitis C virus. Many triggering factors have been described in literature; however, activation of hepatitis C as a trigger for Lucio phenomenon has not been reported. …”
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1054por McClure, C. Patrick, Urbanowicz, Richard A., King, Barnabas J., Cano-Crespo, Sara, Tarr, Alexander W., Ball, Jonathan K.“…A novel and broadly applicable strategy combining site-directed mutagenesis and DNA assembly for constructing seamless viral chimeras is described using hepatitis C virus (HCV) as an exemplar. Full-length HCV genomic cloning cassettes, which contained flexibly situated restriction endonuclease sites, were prepared via a single, site-directed mutagenesis reaction and digested to receive PCR-amplified virus envelope genes by In-Fusion cloning. …”
Publicado 2016
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1055por Campo, David S., Roh, Ha-Jung, Pearlman, Brian L., Fierer, Daniel S., Ramachandran, Sumathi, Vaughan, Gilberto, Hinds, Andrew, Dimitrova, Zoya, Skums, Pavel, Khudyakov, Yury“…BACKGROUND & AIMS: The host genetic environment contributes significantly to the outcomes of hepatitis C virus (HCV) infection and therapy response, but little is known about any effects of HCV infection on the host beyond any changes related to adaptive immune responses. …”
Publicado 2016
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1056“…Genotype 4 chronic hepatitis C (G4 HCV) accounts for 13% of worldwide HCV infections; with 10 million people infected with the virus across the world. …”
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1057por Berera, Shivali, Gomez, Alexandra, Dholaria, Kevin, Arosemena, Leopoldo R., Ladino-Avellaneda, Marco A., Barisoni, Laura, Bhamidimarri, Kalyan R.“…With an undetectable hepatitis C viral load and persistent symptoms despite hepatitis C virus therapy cessation, an upper endoscopy revealed duodenal sloughing, erythema, and bleeding, sparking suspicion for recurrence of cryoglobulinemic vasculitis.…”
Publicado 2016
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1058por von Schaewen, Markus, Dorner, Marcus, Hueging, Kathrin, Foquet, Lander, Gerges, Sherif, Hrebikova, Gabriela, Heller, Brigitte, Bitzegeio, Julia, Doerrbecker, Juliane, Horwitz, Joshua A., Gerold, Gisa, Suerbaum, Sebastian, Rice, Charles M., Meuleman, Philip, Pietschmann, Thomas, Ploss, Alexander“…Hepatitis C virus (HCV) species tropism is incompletely understood. …”
Publicado 2016
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1059“…In the past, interferon-based therapy for chronic hepatitis C infection in patients with Down syndrome was noted to have lower efficacy and potentially higher risk of adverse effects. …”
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1060por Pracoyo, Noer Endah, Suratri, Made Ayu Lely, Roselinda, Roselinda, Setiawaty, Vivi“…This study aims at determining the several associated risk factors with hepatitis C serological status. The study design is cross-sectional. …”
Publicado 2016
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