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11001“…CASE REPORT: Our patient was a 74-year-old white female who had pneumonia and was positive for hepatitis C virus (HCV), and who had been on levofloxacin therapy. …”
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11002por Watanabe, Yuko, Iwamura, Akira, Shimada, Yuichi J., Wakai, Kenji, Tamakoshi, Akiko, Iso, Hiroyasu“…We used a conditional logistic regression analysis to estimate the adjusted relative risks (aRRs) of death from HCC according to the serum TGF-β1 concentrations among 1940 participants including 83 patients with HCC and 1857 controls matched for age, sex, and hepatitis C virus (HCV)-antibody seropositivity. FINDINGS: When serum TGF-β1 was modelled as a continuous variable, the aRR of death from HCC associated with a decrement of 7.9 ng/mL (one standard deviation) in the serum TGF-β1 concentrations was 2.3 (95% CI 1.7–3.0, P < 0.001) for all the subjects. …”
Publicado 2016
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11003por Hong, MeeAe, Schwerk, Johannes, Lim, Chrissie, Kell, Alison, Jarret, Abigail, Pangallo, Joseph, Loo, Yueh-Ming, Liu, Shuanghu, Hagedorn, Curt H., Gale, Michael, Savan, Ram“…Although IFNλ1, IFNλ2, and IFNλ3 act antiviral, genetic association studies have shown that expression of the recently discovered IFNL4 is detrimental to hepatitis C virus (HCV) infection through a yet unknown mechanism. …”
Publicado 2016
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11004por Gokhale, Nandan S., McIntyre, Alexa B.R., McFadden, Michael J., Roder, Allison E., Kennedy, Edward M., Gandara, Jorge A., Hopcraft, Sharon E., Quicke, Kendra M., Vazquez, Christine, Willer, Jason, Ilkayeva, Olga R., Law, Brittany A., Holley, Christopher L., Garcia-Blanco, Mariano A., Evans, Matthew J., Suthar, Mehul S., Bradrick, Shelton S., Mason, Christopher E., Horner, Stacy M.“…We demonstrate that m(6)A modulates infection by hepatitis C virus (HCV). Depletion of m(6)A methyltransferases or an m(6)A demethylase, respectively, increases or decreases infectious HCV particle production. …”
Publicado 2016
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11005por Goto, Kaku, Annan, Dorcas A., Morita, Tomoko, Li, Wenwen, Muroyama, Ryosuke, Matsubara, Yasuo, Ito, Sayaka, Nakagawa, Ryo, Tanoue, Yasushi, Jinushi, Masahisa, Kato, Naoya“…Recently, we identified the anti-tumor ligand MHC class I polypeptide-related sequence A (MICA) gene as a susceptibility gene for hepatitis C virus-induced HCC in a genome-wide association study (GWAS). …”
Publicado 2016
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11006por Li, Yong, Zhu, Chuanlong, Wang, Faxi, Zhu, Tiantian, Li, Jun, Liu, Shufeng, Xiao, Fei“…It has been recently reported that SART1 mediates antiviral effects of IFN-α in the hepatitis C virus (HCV) cell culture model. In this study, we investigated the role of SART1 in antiviral activity of IFN-α against hepatitis B virus (HBV) using blood and liver biopsy samples from chronic hepatitis B patients treated with pegylated IFN-α and HepG2 cells transfected with cloned HBV DNA. …”
Publicado 2016
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11007por Yacoub, Radwa Alaa, Fawzy, Injie Omar, Assal, Reem Amr, Hosny, Karim Adel, Zekri, Abdel-Rahman Nabawy, Esmat, Gamal, El Tayebi, Hend Mohamed, Abdelaziz, Ahmed Ihab“…Methods: miR-34a expression was assessed in hepatitis C virus (HCV)-induced non-metastatic HCC tissues by RT-Q-PCR. …”
Publicado 2016
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11008“…There is confusion as to the definition of the disease entity and its boundaries in the diagnosis of overlap syndrome, drug-induced autoimmune hepatitis, and AIH with concomitant nonalcoholic fatty liver disease (NAFLD) or chronic hepatitis C. Centrilobular zonal necrosis is now included in the histological spectrum of AIH. …”
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11009por Kadokawa, Yukio, Katayama, Kazuhiro, Takahashi, Kozo, Fukushima, Nobuhisa, Tanaka, Setsu, Taniguchi, Yuko, Nawa, Takatoshi, Sakakibara, Mitsuru, Ohkawa, Kazuyoshi“…The classes focused on the following areas: 1) prevention of hepatic cancer; 2) treatment of hepatic cancer; 3) iron restriction diet for hepatitis C patients; and 4) importance of branched-chain amino acid preparations. …”
Publicado 2017
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11010por Magistri, Paolo, Tarantino, Giuseppe, Ballarin, Roberto, Coratti, Andrea, Di Benedetto, Fabrizio“…Nowadays, the epidemiology of HCC is evolving due to the increasing role of non-alcoholic fatty-liver-disease, and the emerging concerns on direct-acting antivirals against hepatitis C virus in terms of HCC incidence. Therefore, a fully multidisciplinary study of the cirrhotic patient is currently more important than ever before, and the management of those patients should be reserved to tertiary referral hepatobiliary centers. …”
Publicado 2017
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11011por Nappi, A., Perrella, A., Bellopede, P., Lanza, A., Izzi, A., Spatarella, M., Sbreglia, C.“…BACKGROUND: Direct Antiviral Agents (DAAs) for HCV therapy represents a step ahead in the cure of chronic hepatitis C. Notwithstanding the promising results in several clinical trials, few data are available on adverse effects in real life settings. …”
Publicado 2017
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11012“…Interleukin (IL)-6 is a multifactorial cytokine known to be increased in patients with chronic hepatitis C (CHC) and to be predictive of depression incidence. …”
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11013“…The World Health Organization ‘Global Health Sector Strategy on Viral Hepatitis 2016–2021’ aimed at the elimination of viral hepatitis as a public health threat provides a significant opportunity to increase efforts for tackling the epidemics of hepatitis B and hepatitis C virus infections across Europe. To support the implementation and monitoring of this strategy, core epidemiological and programmatic indicators have been proposed necessitating specific surveys, the systematic collection of programmatic data and the establishment of monitoring across the care pathway. …”
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11014por Moura, Tuane Carolina Ferreira, Amoras, Ednelza da Silva Graça, Araújo, Mauro Sérgio, Freitas Queiroz, Maria Alice, Conde, Simone Regina Souza da Silva, Demachki, Sâmia, Martins-Feitosa, Rosimar Neris, Machado, Luiz Fernando Almeida, Cayres-Vallinoto, Izaura Maria Vieira, Ishak, Ricardo, Vallinoto, Antonio Carlos Rosário“…Blood samples from patients infected with hepatitis B virus (HBV; n = 65), hepatitis C virus (HCV; n = 92), and a noninfected control group (n = 300) were investigated. …”
Publicado 2017
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11015por Zhong, Yaogang, Guo, Yonghong, Liu, Xiawei, Zhang, Jiaxu, Ma, Tianran, Shu, Jian, Yang, Jiajun, Zhang, Jing, Jia, Zhansheng, Li, Zheng“…Meanwhile, among these lectins, there were 12 lectins (e.g., WFA, GAL-II, and EEL) also exhibited significantly alterations of serum glycopatterns in ACHBLF compared with HBV-infected chronic hepatitis (cHB) (all p ≤ 0.0252). The receiver-operating characteristic (ROC) curve analysis indicated there were 5 lectins (PHA-E + L, BS-I, ECA, ACA, and BPL) had the greatest discriminatory power for distinguishing ACHBLF and HC or cHB, respectively (all p ≤ 0.00136). …”
Publicado 2017
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11016por Lukic, Ruzica, Gajovic, Nevena, Jovanovic, Ivan, Jurisevic, Milena, Mijailovic, Zeljko, Maric, Veljko, Popovska Jovicic, Biljana, Arsenijevic, Nebojsa“…Hepatitis C virus infection (HCV), one of the greatest causes of liver disease, is a frequent complication in patients with end-stage renal disease (ESRD) on dialysis. …”
Publicado 2017
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11017por Mengardi, Chloé, Limousin, Taran, Ricci, Emiliano P., Soto-Rifo, Ricardo, Decimo, Didier, Ohlmann, Théophile“…The genomic RNA of the Hepatitis C Virus is uncapped, non-polyadenylated and harbors a peculiar internal ribosome entry site (IRES) that binds the ribosome directly to the AUG codon. …”
Publicado 2017
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11018por Birger, Ruthie B., Le, Thuy, Kouyos, Roger D., Grenfell, Bryan T., Hallett, Timothy B.“…BACKGROUND: Human Immunodeficiency Virus (HIV) and Hepatitis C Virus (HCV) coinfection is a major global health problem especially among people who inject drugs (PWID), with significant clinical implications. …”
Publicado 2017
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11019“…The rate of VT ranges from 1–28% with hepatitis B virus (HBV) and 3–15% with hepatitis C virus (HCV). VT for both viruses can occur during the intrauterine or peripartum period. …”
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11020“…Six of 8 cases were women and the mean age was 43.8 ± 13.8 years with chronic hepatitis C in 6 cases, malignant melanoma in 2 cases and chronic myelogenous leukemia in 1 case. …”
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