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11121“…Genetic engineering of the RABV has been employed to generate novel vaccines consisting of non-replicating RABV particles expressing chimeric capsid proteins containing human immunodeficiency virus 1 (HIV-1), Middle East respiratory syndrome (MERS-CoV), Ebolavirus, and hepatitis C virus (HCV) sequences. Accordingly, we present a critical discussion that integrates lessons learned from prior RABV research and vaccine development into a working model of a SARS-CoV-2 vaccine that selectively targets and neutralizes CNS penetration of a tightly bound viral nAChR complex.…”
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11122“…Although there are no solid studies to support general recommendations, experiences with other viral infections (hepatitis C, cytomegalovirus) suggest that management of immunosuppression without mycophenolate mofetil or m-Tor inhibitors (drugs that are also associated with leukopenia and lymphopenia) may be beneficial. …”
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11123“…Our report presents the case of a 50-year-old male with a history of intravenous (IV) drug abuse, positive for human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV) antibodies, who was admitted for new-onset headache and brain magnetic resonance imaging (MRI) findings suggesting CSF hypotension. …”
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11124por Saint, Angélique, Benchetrit, Maxime, Novellas, Sébastien, Ouzan, Denis, Falk, Alexander Tuan, Leysalle, Axel, Barriere, Jérome“…METHODS AND RESULTS: We present the case of a 72-year-old male patient treated for metastatic HCC-ICC due to a viral hepatitis C cirrhosis in progression after two lines of treatment. …”
Publicado 2020
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11125por Tovo, Pier-Angelo, Garazzino, Silvia, Daprà, Valentina, Alliaudi, Carla, Silvestro, Erika, Calvi, Cristina, Montanari, Paola, Galliano, Ilaria, Bergallo, Massimiliano“…Chronic hepatitis C virus (HCV) infection is associated with several hepatic and extrahepatic complications, including cancers and autoimmune disorders, whose frequency is reduced but not abolished after drug-induced viral clearance. …”
Publicado 2020
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11126“…METHODS: Minimum costs of production were estimated from the costs of active pharmaceutical ingredients using established methodology, which had good predictive accuracy for medicines for hepatitis C and HIV amongst others. Data were extracted from global export shipment records or analysis of the route of chemical synthesis. …”
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11127por Matsunaga, Yutaro, Ariizumi, Shunichi, Shibuya, Go, Uemura, Shuichiro, Kato, Takaaki, Yazawa, Takehisa, Yamashita, Shingo, Omori, Akiko, Higuchi, Ryota, Takahashi, Yutaka, Kotera, Yoshihito, Egawa, Hiroto, Yamamoto, Masakazu“…He had a history of chronic hepatitis C. Computed tomography showed a liver tumor 20 mm in diameter in segment 6 of the Couinaud classification, with ring calcification. …”
Publicado 2020
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11128por Bobardt, Michael, Hansson, Magnus Joakim, Mayo, Patrick, Ure, Daren, Foster, Robert, Gallay, Philippe“…Since we recently demonstrated that both CRV431 and NV556 also inhibit the development of liver fibrosis and hepatocellular carcinoma in nonviral-induced non-alcoholic steatohepatitis mouse models, our present data suggest that the two entirely structurally different CypIs—CRV431 and NV556—derived from unrelated natural products, represent attractive partners to current direct-acting agent (DAA) regimens for the treatment of hepatitis C and liver diseases.…”
Publicado 2020
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11129“…The patient with a past medical history significant for hepatitis C, intravenous (IV) drug use, and nicotine dependence presented with severe back pain that started one month ago. …”
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11130por Kim, Kiyoon, Lee, Young-seok, Jeong, Suyun, Kim, Daehong, Chon, Suk, Pak, Youngmi Kim, Kim, Sungsoo, Ha, Joohun, Kang, Insug, Choe, Wonchae“…Hepatic hepcidin is a well-known major iron regulator and has been reported to be closely related to hepatitis C virus (HCV) replication. However, pharmacological targeting of the hepcidin in HCV replication has not been reported. …”
Publicado 2020
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11131por Azadbakht, Mojtaba, Ardakani, Masoud Torabi, Delirakbariazar, Marziyeh, Kasraian, Leila, Khaledi, Azad, Foruozandeh, Hossein, Salah, Alireza, Maleki, Fahimeh, Eshraghi, Mohsen“…This study aimed to survey the prevalence and trend of hepatitis B virus (HBV), hepatitis C virus (HCV), and Human immunodeficiency virus (HIV) among blood donors of Fars province, Iran (2006–2018). …”
Publicado 2020
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11132“…It has been shown that low Vit D level is associated with viral infection, and Vit D supplementation is beneficial for people infected with viruses, such as HIV and hepatitis C virus. Although COVID-19 is a respiratory disease, the morbidity and mortality of this disease are driven by coagulopathy. …”
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11133por Biscornet, Leon, de Comarmond, Jeanine, Bibi, Jastin, Mavingui, Patrick, Dellagi, Koussay, Tortosa, Pablo, Pagès, Frédéric“…Leptospirosis was positively associated in univariate analysis with socio-professional and clinical variables including gardening/farming, oliguria, jaundice, conjunctivitis, history of hepatitis C virus infection, anemia, thrombocytopenia, and/or biological renal failure. …”
Publicado 2020
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11134por Ochiai, Yushi, Sumi, Koichiro, Sano, Emiko, Yoshimura, Sodai, Yamamuro, Shun, Ogino, Akiyoshi, Ueda, Takuya, Suzuki, Yutaka, Nakayama, Tomohiro, Hara, Hiroyuki, Katayama, Yoichi, Yoshino, Atsuo“…Ribavirin, an anti-viral agent which is one of the standard agents for treatment of chronic hepatitis C in combination with interferon (IFN), was recently revealed to have an antitumor potential towards various tumor cells, including malignant glioma cells. …”
Publicado 2020
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11135por Hargreaves, Sally, Nellums, Laura B., Johnson, Catherine, Goldberg, Jacob, Pantelidis, Panagiotis, Rahman, Asif, Friedland FMedSci, Jon S.“…RESULTS: 96 economic migrants, asylum seekers and refugees from 43 countries were screened (46 [47.9%] women; mean age 35.2 years [SD 11.7; range 18–73]; mean time in the UK 4.8 years [SD 3.2; range 0–10]). 14 migrants (14.6%) tested positive for LTBI alongside HIV [1], hepatitis B [2], and hepatitis C [1] Of migrants with LTBI, 5 (35.7%) were successfully engaged in treatment. 74 (77.1%) migrants reported no previous screening since migrating to the UK. …”
Publicado 2020
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11136“…Additional data for Human Immunodeficiency Virus, syphilis and hepatitis C virus were also collected. Data were analysed using NCSS statistical software. …”
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11137“…More viable cells were obtained from cirrhotic livers caused by chronic hepatitis B as compared to chronic hepatitis C in the same MELD score range. There was no correlation between the clinical and histological disease severity scores of liver cirrhosis and the outcome of hepatocytes isolation. …”
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11138por Alothaid, Hani, Aldughaim, Mohammed S. K., El Bakkouri, Karim, AlMashhadi, Sufana, Al-Qahtani, Ahmed A.“…A comparative analysis between SARS-CoV-2 and Hepatitis C Virus (HCV) can expand the available knowledge regarding the virology and potential drug targets against these viruses. …”
Publicado 2020
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11139“…Needle-stick injuries (NSIs) pose serious health risks and can transmit blood-borne diseases (BBDs), such as hepatitis B virus, hepatitis C virus, and human immunodeficiency virus from the patient to the staff member. …”
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11140“…Although there are no solid studies to support general recommendations, experiences with other viral infections (hepatitis C, cytomegalovirus) suggest that management of immunosuppression without mycophenolate mofetil or m-Tor inhibitors (drugs that are also associated with leukopenia and lymphopenia) may be beneficial. …”
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