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  1. 11301
    “…Here we describe a CID module based on the orally available, approved, small molecule simeprevir and its target, the NS3/4A protease from hepatitis C virus. We demonstrate the utility of this CID module as a molecular switch to control biological processes such as gene expression and apoptosis in vitro, and show that the CID system can be used to rapidly induce apoptosis in tumor cells in a xenograft mouse model, leading to complete tumor regression.…”
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    A simeprevir-inducible molecular switch for the control of cell and gene therapies
  2. 11302
    “…The leading causes of liver disease were hepatitis C (113 cases, 34.6%) and alcohol-related liver disease (97 cases, 29.7%). …”
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    Assessment of the need for routine intraoperative cell salvage in liver transplantation
  3. 11303
    “…We applied our method to a large set of genome sequences from human immunodeficiency virus (HIV) and hepatitis C virus (HCV) as well as to simulated recombined genome sequences. …”
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    A jumping profile Hidden Markov Model and applications to recombination sites in HIV and HCV genomes
  4. 11304
    “…BACKGROUND: Percutaneous exposure incidents facilitate transmission of bloodborne pathogens such as human immunodeficiency virus (HIV), hepatitis C virus (HCV) and hepatitis B virus (HBV). …”
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    Percutaneous injuries among dental professionals in Washington State
  5. 11305
    por Sallie, Richard
    Publicado 2007
    “…Interferon (IFN) and ribavirin, are effective drugs used to treat hepatitis C (HCV), but the mechanism(s) of their action are uncertain. …”
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    Replicative Homeostasis III: implications for antiviral therapy and mechanisms of response and non-response
  6. 11306
    “…Canine cirrhotic samples were compared to human liver samples from cirrhotic stages of alcoholic liver disease (hALC) and chronic hepatitis C infection (hHC). RESULTS: Canine specific mRNA expression of the regenerative hepatocyte growth factor (HGF) signaling pathway and relevant down-stream pathways were measured by semi-quantitative PCR and Western blot (STAT3, PKB, ERK1/2, and p38-MAPK). …”
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    Major HGF-mediated regenerative pathways are similarly affected in human and canine cirrhosis
  7. 11307
    “…BACKGROUND/AIMS: A recent decrease in patient survival has been reported among hepatitis C virus (HCV)-infected liver transplant recipients and this may be attributable to progression of fibrosis. …”
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    NIM811, a nonimmunosuppressive cyclosporine analogue, suppresses collagen production and enhances collagenase activity in hepatic stellate cells
  8. 11308
    “…The hepatitis C virus (HCV) NS5B is essential for viral RNA replication and is therefore a prime target for development of HCV replication inhibitors. …”
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    Identification and characterization of coumestans as novel HCV NS5B polymerase inhibitors
  9. 11309
    “…It has recently been identified as the putative receptor for the Hepatitis C Virus envelope E2 glycoprotein (HCV-E2). …”
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    High-Level Expression, Single-Step Immunoaffinity Purification and Characterization of Human Tetraspanin Membrane Protein CD81
  10. 11310
    “…LPS levels were higher in AIDS patients using intravenous heroin and/or ethanol, or with Hepatitis C virus (HCV) co-infection, compared to control groups. …”
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    Microbial Translocation Is Associated with Increased Monocyte Activation and Dementia in AIDS Patients
  11. 11311
    por Mak, Donna B, Watkins, Rochelle E
    Publicado 2008
    “…Compared with excluding notifications with unknown Aboriginality data from the analysis, or apportioning notifications with unknown Aboriginality based on the proportion of cases with known Aboriginality, the rate ratios of chlamydia, syphilis and hepatitis C among Aboriginal relative to non-Aboriginal people decreased when Aboriginality data from data linkage was included. …”
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    Improving the accuracy of Aboriginal and non-Aboriginal disease notification rates using data linkage
  12. 11312
    “…BACKGROUND: Chronic hepatitis C virus (HCV) infection results from weak or absent T cell responses. …”
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    Immunostimulatory effects of three classes of CpG oligodeoxynucleotides on PBMC from HCV chronic carriers
  13. 11313
    “…CONCLUSIONS/SIGNIFICANCE: Tetraspanins fulfill various roles in the life cycle of a number of important viral pathogens, including human immunodeficiency virus (HIV) and hepatitis C virus (HCV). However, their involvement in endocytosis of viral particles has not been proven. …”
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    Clathrin- and Caveolin-Independent Entry of Human Papillomavirus Type 16—Involvement of Tetraspanin-Enriched Microdomains (TEMs)
  14. 11314
    “…BACKGROUND AND AIMS: Hepatitis C Virus (HCV)-related liver disease progresses more rapidly in individuals co-infected with Human Immunodeficiency Virus-1 (HIV), although the underlying immunologic mechanisms are unknown. …”
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    HIV-Specific T-Cells Accumulate in the Liver in HCV/HIV Co-Infection
  15. 11315
    “…The groups of patients with cirrhosis due to alcohol, hepatitis C, or cholestatic liver disease did not differ in severity of liver cirrhosis or the prevalence of hepatic encephalopathy (p > 0.05). …”
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    Type and etiology of liver cirrhosis are not related to the presence of hepatic encephalopathy or health-related quality of life: a cross-sectional study
  16. 11316
    “…OBJECTIVE: The objective of the study reported here was to determine the prevalence of Human Immunodeficiency and Hepatitis C viruses (respectively, HIV and HCV) in the earthquake-affected communities of Pakistan. …”
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    Prevalence of HCV and HIV infections in 2005-Earthquake-affected areas of Pakistan
  17. 11317
    por Bernstein, L. H., Coles, M., Viner, N.
    Publicado 1995
    “…The safety of the blood supply, an issue in the 1970s and 1980s, created an increased need to screen the blood supply for HIV-1 and hepatitis C virus infections. The possibility exists that other contamination could again affect the blood supply. …”
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    Bridgeport Hospital autologous blood donation experience from 1992 to 1996.
  18. 11318
    “…Premature delivery was significantly more common in the group of pregnant addicts (21% vs. 6%); 49% of pregnant addicts were carriers of hepatitis C virus (HCV) and 14% of hepatitis B virus (HBV). …”
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    Maternal and Neonatal Effects of Substance Abuse during Pregnancy: Our Ten-year Experience
  19. 11319
    “…In Mexico, Texas and New Mexico, respectively: hepatitis B virus (HBV) was seen in 88.3%, 48.6% and 59.6% of participants; hepatitis C virus (HCV) in 98.7%, 76.4% and 80.0%; human immunodeficiency virus (HIV) in 2.1%, 10.0% and 1.0%; and syphilis in 4.0%, 9.9% and 3.0%. …”
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    Seroprevalence of select bloodborne pathogens and associated risk behaviors among injection drug users in the Paso del Norte region of the United States – Mexico border
  20. 11320
    “…Of the 12 countries included in the study, nine screened all donors for HIV; three screened all donors for hepatitis B virus (HBV); two screened all donors for Trypanosoma cruzi; none screened all donors for hepatitis C virus (HCV); and six screened some donors for syphilis. …”
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    Risk for transfusion-transmitted infectious diseases in Central and South America.
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