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11461por Yadav, Anitha D., Chang, Yu-Hui, Aqel, Bashar A., Byrne, Thomas J., Chakkera, Harini A., Douglas, David D., Mulligan, David C., Rakela, Jorge, Vargas, Hugo E., Carey, Elizabeth J.“…Predictors for NODAT in LDLT recipients were hepatitis C (HCV) and treated acute cellular rejection (ACR). …”
Publicado 2013
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11462por Chen, Kangmei, Shi, Weimei, Xin, Zhenhui, Wang, Huifen, Zhu, Xilin, Wu, Xiaopan, Li, Zhuo, Li, Hui, Liu, Ying“…BACKGROUND: Genome-wide association studies (GWAS) have identified three loci (rs17401966 in KIF1B, rs7574865 in STAT4, rs9275319 in HLA-DQ) as being associated with hepatitis B virus-related hepatocellular carcinoma (HBV-related HCC) in a Chinese population, two loci (rs2596542 in MICA, rs9275572 located between HLA-DQA and HLA-DQB) with hepatitis C virus-related HCC (HCV-related HCC) in a Japanese population. …”
Publicado 2013
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11463por Watashi, Koichi, Liang, Guoxin, Iwamoto, Masashi, Marusawa, Hiroyuki, Uchida, Nanako, Daito, Takuji, Kitamura, Kouichi, Muramatsu, Masamichi, Ohashi, Hirofumi, Kiyohara, Tomoko, Suzuki, Ryosuke, Li, Jisu, Tong, Shuping, Tanaka, Yasuhito, Murata, Kazumoto, Aizaki, Hideki, Wakita, Takaji“…The antiviral effect of IL-1/TNFα was also observed on different HBV genotypes but not on hepatitis C virus. These results demonstrate that proinflammatory cytokines IL-1/TNFα trigger a novel antiviral mechanism involving AID to regulate host cell permissiveness to HBV infection.…”
Publicado 2013
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11464por Poon, Art F. Y., Walker, Lorne W., Murray, Heather, McCloskey, Rosemary M., Harrigan, P. Richard, Liang, Richard H.“…For example, viruses that can establish persistent chronic infections (such as HIV and hepatitis C virus) form a distinct cluster. Although the visibly ‘star-like’ shape characteristic of trees from these viruses has been well-documented, we show that established methods for quantifying tree shape fail to distinguish these trees from those of other viruses. …”
Publicado 2013
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11465por El-Tayeh, Sarmad F., Hussein, Tarek D., El-Houseini, Motawa E., Amer, Mahmoud A., El-Sherbini, Mamdooh, Elshemey, Wael M.“…A total of 96 patients with different liver diseases such as HCC, hepatitis C virus (HCV), hepatitis B virus (HBV) and cirrhotic patients are included in this study. …”
Publicado 2012
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11466“…Four patients were intravenous drug users and four patients had hepatitis C. All five patients were treated with systemic antifungal therapy and intravitreal antifungal injections, and all required vitrectomy. …”
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11467por Muriuki, Beatrice Mukami, Gicheru, Michael Muita, Wachira, Dorcas, Nyamache, Anthony Kebira, Khamadi, Samoel Ashimosi“…BACKGROUND: Hepatitis B virus (HBV) and Hepatitis C virus (HCV) co-infections among HIV-1 infected individuals are growing worldwide health problems characterized by lack of effective vaccines, need for expensive treatment, chronicity of morbidity and associated mortality. …”
Publicado 2013
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11468“…BACKGROUND: Two kinds of peginterferons, peginterferon-α2a (PEG-IFN-α2a) and peginterferon-α2b (PEG-IFN-α2b), are used in the treatment of chronic hepatitis C virus (HCV) infection. However, it is unclear which is better in terms of virological responses and patient compliance. …”
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11469por McElroy, Kerensa, Zagordi, Osvaldo, Bull, Rowena, Luciani, Fabio, Beerenwinkel, Niko“…We demonstrate these findings on two control data sets, showing that SNV detection is more reliable on a high diversity human immunodeficiency virus sample as compared to a moderate diversity sample of hepatitis C virus. Finally, we show that in situations where probabilistic clustering retains false positive SNVs (for instance due to insufficient sample diversity or systematic errors), applying a strand bias test based on a beta-binomial model of forward read distribution can improve precision, with negligible cost to true positive recall. …”
Publicado 2013
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11470“…Theoretically, idiopathic interstitial pneumonias could be caused by the Epstein-Barr virus, cytomegalovirus, adenovirus, hepatitis C virus, respiratory syncytial virus, and herpesvirus, which may be present in such small amounts or such configuration that routine histopathological analysis or viral culture techniques cannot detect them. …”
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11471por Gebert, Luca F. R., Rebhan, Mario A. E., Crivelli, Silvia E. M., Denzler, Rémy, Stoffel, Markus, Hall, Jonathan“…MiR-122 is a liver-specific miRNA with an important role in the life cycle of hepatitis C virus (HCV). It is the target of miravirsen (SPC3649), an antimiR drug candidate currently in clinical testing for treatment of HCV infections. …”
Publicado 2014
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11472por Irfan, Syed Mohammad, Uddin, Jamal, Zaheer, Hasan Abbas, Sultan, Sadia, Baig, Amjad“…Objective: To determine the prevalence of Hepatitis-B, Hepatitis-C and Human Immunodeficiency infections in replacement blood donors. …”
Publicado 2013
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11473por Hinrichsen, Inga, Kemp, Matthias, Peveling-Oberhag, Jan, Passmann, Sandra, Plotz, Guido, Zeuzem, Stefan, Brieger, Angela“…Looking at hepatocellular carcinoma (HCC) specific protein silencing was previously demonstrated to be associated with the Hepatitis C virus (HCV). However, the proposed HCV dependent promoter methylation of DNA mismatch repair (MMR) genes and thereby enhanced progression of hepatocarcinogenesis has been the subject of controversial discussion. …”
Publicado 2014
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11474por Fernandez-Ponce, Cecilia, Dominguez-Villar, Margarita, Aguado, Enrique, Garcia-Cozar, Francisco“…Accumulating evidence suggests that proteins from Hepatitis C virus can suppress host immune responses. …”
Publicado 2014
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11475por Tseng, Chin-Kai, Lin, Chun-Kuang, Chang, Hsueh-Wei, Wu, Yu-Hsuan, Yen, Feng-Lin, Chang, Fang-Rong, Chen, Wei-Chun, Yeh, Chi-Chen, Lee, Jin-Ching“…In addition to the previous investigations of bioactivity of aqueous extract of the edible Gracilaria tenuistipitata (AEGT) against H(2)O(2)-induced DNA damage and hepatitis C virus replication, the purpose of this study is to evaluate the potential therapeutic properties of AEGT against inflammation and hepatotoxicity using lipopolysaccharide (LPS)-stimulated mouse RAW 264.7 cells, primary rat peritoneal macrophages and carbon tetrachloride (CCl(4))-induced acute hepatitis model in rats. …”
Publicado 2014
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11476por Gawlik, Katarzyna, Baugh, James, Chatterji, Udayan, Lim, Precious J., Bobardt, Michael D., Gallay, Philippe A.“…Hepatitis C virus (HCV) infection is a major cause of liver disease. …”
Publicado 2014
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11477“…Hepatitis C virus (HCV) infection is an alarming and growing threat to public health. …”
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11478por Denise, Hubert, Moschos, Sterghios A., Sidders, Benjamin, Burden, Frances, Perkins, Hannah, Carter, Nikki, Stroud, Tim, Kennedy, Michael, Fancy, Sally-Ann, Lapthorn, Cris, Lavender, Helen, Kinloch, Ross, Suhy, David, Corbau, Romu“…TT-034 (PF-05095808) is a recombinant adeno-associated virus serotype 8 (AAV8) agent expressing three short hairpin RNA (shRNA) pro-drugs that target the hepatitis C virus (HCV) RNA genome. The cytosolic enzyme Dicer cleaves each shRNA into multiple, potentially active small interfering RNA (siRNA) drugs. …”
Publicado 2014
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11479por De Re, Valli, Gragnani, Laura, Fognani, Elisa, Piluso, Alessia, Izzo, Francesco, Mangia, Alessandra, Crovatto, Marina, Gava, Graziella, Casarin, Pietro, Sansonno, Domenico, Racanelli, Vito, De Vita, Salvatore, Pioltelli, Pietro, Caggiari, Laura, De Zorzi, Mariangela, Berretta, Massimiliano, Gini, Andrea, Zucchetto, Antonella, Buonaguro, Franco Maria, De Paoli, Paolo, Zignego, Anna Linda“…With the aim of investigating whether interleukin 28B gene (IL28B) rs1297860 polymorphism is associated with different hepatitis C (HCV) infection statuses, we compared IL28B allelic distribution in an Italian case series of 1050 patients with chronic infection and different outcomes, 47 individuals who spontaneously cleared HCV, and 178 blood donors. …”
Publicado 2014
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11480por Rizzo, Leonardo, Attanasio, Massimo, Pinzone, Marilia Rita, Berretta, Massimiliano, Malaguarnera, Michele, Morra, Aldo, L'Abbate, Luca, Balestreri, Luca, Nunnari, Giuseppe, Cacopardo, Bruno“…In our study, we evaluated the feasibility of a new sampling method for splenic stiffness (SS) measurement by Quantitative Acoustic Radiation Force Impulse Elastography (Virtual Touch Tissue Quantification (VTTQ)).We measured SS in 54 patients with HCV-related cirrhosis of whom 28 with esophageal varices (EV), 27 with Chronic Hepatitis C (CHC) F1–F3, and 63 healthy controls. VTTQ-SS was significantly higher among cirrhotic patients with EV (3.37 m/s) in comparison with controls (2.19 m/s, P < 0.001), CHC patients (2.37 m/s, P < 0.001), and cirrhotic patients without EV (2.7 m/s, P < 0.001). …”
Publicado 2014
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