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11981“…Three endpoints were modeled: Ames mutagenicity, inhibition of P. falciparum Dd2 and inhibition of Hepatitis C Virus, with training sets ranging from 7,866 to 31,919 compounds. …”
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11982“…Occupational exposure to needle stick injury represents the most common sources of infection such as hepatitis B virus, hepatitis C virus, and human immunodeficiency virus. …”
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11983por Marticorena Garcia, Stephan R., Althoff, Christian E., Dürr, Michael, Halleck, Fabian, Budde, Klemens, Grittner, Ulrike, Burkhardt, Christian, Jöhrens, Korinna, Braun, Jürgen, Fischer, Thomas, Hamm, Bernd, Sack, Ingolf, Guo, Jing“…Besides the liver, hepatitis C virus (HCV) infection also affects kidney allografts. …”
Publicado 2021
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11984por Haroon, Sabrina, Ko, Stephanie, Wong, Alvin, Tan, Poh-Seng, Lee, Evan, Lau, Titus“…PATIENT CONCERNS: A 65-year-old man with end stage renal disease on maintenance conventional hemodialysis and had concomitant stable Child-Pugh class B liver cirrhosis consequent of hepatitis C infection was started on sunitinib for metastatic renal cell carcinoma. …”
Publicado 2021
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11985por Mangia, Alessandra, Albanese, Anthony P., Bourliére, Marc, Craxi, Antonio, Dieterich, Douglas, Solomon, Sunil, Vanstraelen, Kim, Hernandez, Candido, Turnes, Juan“…The availability of pangenotypic direct-acting antivirals for treatment of hepatitis C (HCV) has provided an opportunity to simplify patient pathways. …”
Publicado 2021
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11986“…Since the 1950s, great efforts have been made to develop antiviral agents against many infectious diseases such as human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV), human cytomegalovirus (HCMV), herpes simplex virus (HSV), and varicella-zoster virus (VZV). …”
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11987por Zhou, Yihong, Yang, Zhongping, Liu, Min, Lu, Yanqiu, Qin, Yuanyuan, He, Xiaoqing, Zeng, Yanming, Harypursat, Vijay, Chen, Yaokai“…In the older group, independent predictors of death included: being urban residents, nadir CD4+ T-cell counts <200 cells/μL, not being on cART, and having comorbidities such as Pneumocystis pneumonia, hepatitis C, talaromycosis, non-AIDS malignancy, and kidney disease. …”
Publicado 2021
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11988por Hashmi, Zahid Yasin, Zia, Muhammad Qasim, Bajwa, Akram, Ahmed, Maqsood, Anwer, Naveed, Raza, Mahwish, Baqar, Jaffer Bin“…OBJECTIVE: The study aimed to assess the safety profile of Direct Acting Anti-Viral’s (DAAs) among patients with chronic Hepatitis C Virus (HCV). METHODS: This multicenter, analytical cross-sectional study was conducted in six gastroenterology and Hepatology centers including Liver Center Faisalabad, Allama Iqbal Medical Institute and Liver Center DHQ Hospital Sialkot, Isra Hospital Hyderabad, Allied Hospital Faisalabad and Rehman Medical Institute Peshawar, between May 2018 and May 2019. …”
Publicado 2021
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11989por Abdulla, Maheeba, Ghuloom, Mohamed, Nass, Hafsa, Mohammed, Nafeesa, Farid, Eman, ALQamish, Jehad“…There was no significant difference with regard to the prevalence of hepatitis C virus, human immunodeficiency virus, hepatocellular carcinoma, or liver transplantation between HBe‐positive and ‐negative patients (P ≥ 0.05). …”
Publicado 2021
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11990por Isobe, Yuki, Asakura, Hiroki, Tsujiguchi, Hiromasa, Kannon, Takayuki, Takayama, Hiroaki, Takeshita, Yumie, Ishii, Kiyo-aki, Kanamori, Takehiro, Hara, Akinori, Yamashita, Tatsuya, Tajima, Atsushi, Kaneko, Shuichi, Nakamura, Hiroyuki, Takamura, Toshinari“…Serum levels of selenoprotein P are elevated during aging and in people with type 2 diabetes, non-alcoholic fatty liver disease, and hepatitis C. However, how serum levels of full-length selenoprotein P are regulated largely remains unknown, especially in the general population. …”
Publicado 2021
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11991por Yoshioka, Manabu, Sawada, Yu, Saito-Sasaki, Natsuko, Yoshioka, Haruna, Hama, Kayo, Omoto, Daisuke, Ohmori, Shun, Okada, Etsuko, Nakamura, Motonobu“…Telaprevir used as a protease inhibitor against hepatitis C virus is frequently associated with cutaneous adverse reactions. …”
Publicado 2021
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11992por McIntosh, Alec T., Wei, Renhuizi, Ahn, Jaeil, Aouizerat, Brad E., Kassaye, Seble G., Augenbraun, Michael H., Price, Jennifer C., French, Audrey L., Gange, Stephen J., Anastos, Kathryn M., Goldman, Radoslav“…HIV coinfection is associated with more rapid liver fibrosis progression in hepatitis C (HCV) infection. Recently, much work has been done to improve outcomes of liver disease and to identify targets for pharmacological intervention in coinfected patients. …”
Publicado 2021
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11993por Boccuto, Adele, Dragoni, Filippo, Picarazzi, Francesca, Lai, Alessia, Della Ventura, Carla, Veo, Carla, Giammarino, Federica, Saladini, Francesco, Zehender, Gianguglielmo, Zazzi, Maurizio, Mori, Mattia, Vicenti, Ilaria“…The nucleotide analog sofosbuvir, licensed for the treatment of hepatitis C, recently revealed activity against the Zika virus (ZIKV) in vitro and in animal models. …”
Publicado 2021
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11994por Kausar, Shamaila, Said Khan, Fahad, Ishaq Mujeeb Ur Rehman, Muhammad, Akram, Muhammad, Riaz, Muhammad, Rasool, Ghulam, Hamid Khan, Abdul, Saleem, Iqra, Shamim, Saba, Malik, Arif“…Though, there are a couple of drugs for herpesviruses, many for influenza and some new antiviral drugs for treating hepatitis C infection and HIV. Action mechanism of antiviral drugs consists of its transformation to triphosphate following the viral DNA synthesis inhibition. …”
Publicado 2021
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11995“…In a small number of clinical trials, cannabinoids used to treat cancer, HIV, multiple sclerosis, hepatitis C, Crohn's disease, and chronic neuropathic pain report decreases in anxiety or depression symptoms and presented sedative and anxiolytic effects. …”
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11996“…Quinoline derivatives were found potent against various strains of viruses like zika virus, enterovirus, herpes virus, human immunodeficiency virus, ebola virus, hepatitis C virus, SARS virus and MERS virus etc.…”
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11997por Hajikhezri, Zamaneh, Roohvand, Farzin, Maleki, Monireh, Shahmahmoodi, Shohreh, Amirzargar, Ali Akbar, Keshavarz, Abolfazl, Seyed, Negar, Farahmand, Mohammad, Samimi-Rad, Katayoun“…Feeble cellular responses induced by T cell-based vaccines are a major challenge for the development of an effective vaccine against Hepatitis C virus (HCV) infection. To address this challenge, the potential of N-terminal fragment of gp96 heat shock protein (rNT (gp96) as an adjuvant was evaluated and compared to that of the CpG (as a recognized Th1-type adjuvant) in the formulation of HCV core/NS3 antigens in three immunization strategies of protein/protein, DNA/DNA, and DNA/protein. …”
Publicado 2021
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11998“…Many RNA viruses and their components, such as encephalomyocarditis virus (EMCV) 2B viroporin, the viral RNA of hepatitis C virus, the influenza virus M2 viroporin, the respiratory syncytial virus (RSV) small hydrophobic (SH) viroporin, and the human rhinovirus (HRV) 2B viroporin can activate the Nod-like receptor (NLR) family pyrin domain-containing 3 (NLRP3) inflammasome to influence the inflammatory response. …”
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11999por Behera, Santosh Kumar, Vhora, Nazmina, Contractor, Darshan, Shard, Amit, Kumar, Dinesh, Kalia, Kiran, Jain, Alok“…Keeping this hypothesis intact, the present study describes for the first-time, Grazoprevir, an FDA approved anti-viral drug primarily approved for Hepatitis C Virus (HCV), mediated multiple pathway control via synergistic inhibition of viral entry targeting host cell Angiotensin-Converting Enzyme 2 (ACE-2)/transmembrane serine protease 2 (TMPRSS2) and viral replication targeting RNA-dependent RNA polymerase (RdRP). …”
Publicado 2021
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12000“…Currently, prenylation has been detected in type 1 adenovirus, hepatitis C virus, several herpes viruses, influenza virus, HIV. …”
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