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12001por Sellau, Julie, Puengel, Tobias, Hoenow, Stefan, Groneberg, Marie, Tacke, Frank, Lotter, Hannelore“…This includes not only hepatotropic viruses (e.g., hepatitis B, hepatitis C) but also bacterial and parasitic infections such as amebiasis, leishmaniasis, schistosomiasis, or echinococcosis. …”
Publicado 2021
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12002“…The remaining issue has been to develop novel drugs that can cure HBV infection. Hepatitis C virus (HCV), on the other hand, is a hepatotropic virus that is parenterally transmitted. …”
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12003Acute severe autoimmune hepatitis with anti-rods and rings autoantibodies; literature first evidence“…Aab targeting these relatively unknown structures has been observed in Hepatitis C virus (HCV) patients who have undergone treatment with pegylated interferona/ ribavirin (IFN/RBV) therapy. …”
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12004por Karam, Hala A., Bessa, Sahar S., Ali, Ehab M. M., Diab, Thoria, Mohamed, Tarek M.“…METHODS: Serum LEP level and LEPR Q223R gene polymorphism were determined in 300 patients with liver disease categorized equally into five groups’ healthy volunteers, patients with hepatitis C (HCV), patients with non-alcoholic steatohepatitis (NASH), liver cirrhosis and HCC. …”
Publicado 2020
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12005por Saad, Hind, Zahran, Magdy A-H, Hendy, Olfat, Abdel-Samiee, Mohamed, Bedair, Hanan M, Abdelsameea, Eman“…BACKGROUND: Chronic hepatitis C (CHC) virus infection is one of major risk factors of hepatocellular carcinoma (HCC) in Egypt, which is a major cause of cancer mortalityin the world. …”
Publicado 2020
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12006por Ribeiro, Luís Mata, Carvalho, Sara, Guimarães, Diogo, Vilela, Manuel, Guerra, Ana S.“…CASE REPORT: We report the clinical case of a 58-year-old Caucasian male, ex-smoker, with a medical history of a chronic hepatitis C virus infection, liver cirrhosis, and diabetes mellitus that developed extensive osteomyelitis of the middle and distal phalanx of his right ring finger caused by S. anginosus and needed amputation for infection control. …”
Publicado 2020
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12007“…The projects included hypoglycemia screening, hepatitis C virus and human immunodeficiency virus screening, and statin use evaluations for atherosclerotic cardiovascular disease risk reduction. …”
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12008por Lo, Ho Sing, Hui, Kenrie Pui Yan, Lai, Hei-Ming, He, Xu, Khan, Khadija Shahed, Kaur, Simranjeet, Huang, Junzhe, Li, Zhongqi, Chan, Anthony K. N., Cheung, Hayley Hei-Yin, Ng, Ka-Chun, Ho, John Chi Wang, Chen, Yu Wai, Ma, Bowen, Cheung, Peter Man-Hin, Shin, Donghyuk, Wang, Kaidao, Lee, Meng-Hsuan, Selisko, Barbara, Eydoux, Cecilia, Guillemot, Jean-Claude, Canard, Bruno, Wu, Kuen-Phon, Liang, Po-Huang, Dikic, Ivan, Zuo, Zhong, Chan, Francis K. L., Hui, David S. C., Mok, Vincent C. T., Wong, Kam-Bo, Mok, Chris Ka Pun, Ko, Ho, Aik, Wei Shen, Chan, Michael Chi Wai, Ng, Wai-Lung“…Using a multidisciplinary approach, we identified and validated the hepatitis C virus (HCV) protease inhibitor simeprevir as an especially promising repurposable drug for treating COVID-19. …”
Publicado 2021
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12009“…Risk factors include genetic factors, environmental exposures, and several infections including hepatitis B, hepatitis C, Helicobacter pylori, Toxoplasma gondi, and cytomegalovirus. …”
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12010“…Recently, several studies have shown that m(6)A methylation sites have been identified in hepatitis B virus (HBV) transcripts and the hepatitis C virus (HCV) RNA genome. Here, we review the role of m(6)A modification in HBV/HCV replication and its contribution to liver disease pathogenesis. …”
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12011“…CASE SUMMARY: A 65-year-old female with a previous history of hepatitis C and a distant history of low grade, well-differentiated rectal neuroendocrine tumor was found to have two liver lesions in segment 4 and segment 7 on imaging. …”
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12012por Kim, Dong Hwi, Yong, Hyo Jeong, Mander, Sunam, Nguyen, Huong Thi, Nguyen, Lan Phuong, Park, Hee-Kyung, Cha, Hyo Kyeong, Kim, Won-Ki, Hwang, Jong-Ik“…Liver cancer is highly related to inflammation as more than 90% of liver cancer arises in the context of hepatic inflammation, such as hepatitis B virus and hepatitis C virus infection. Despite significant improvements in the therapeutic modalities for liver cancer, patient prognosis is not satisfactory due to the limited efficacy of current drug therapies in anti-metastatic activity. …”
Publicado 2021
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12013por Collison, Adam M., Sokulsky, Leon A., Kepreotes, Elizabeth, Pereira de Siqueira, Ana, Morten, Matthew, Edwards, Michael R., Walton, Ross P., Bartlett, Nathan W., Yang, Ming, Nguyen, Thi Hiep, Johnston, Sebastian L., Foster, Paul S., Mattes, Joerg“…Higher miR-122 expression was associated with worse clinical outcomes, highlighting the potential use of anti-miR-122 oligonucleotides, successfully trialed for treatment of hepatitis C, as potential therapeutics for RV-induced bronchiolitis and asthma exacerbations.…”
Publicado 2021
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12014por Łapiński, Tadeusz Wojciech, Tarasik, Aleksandr, Januszkiewicz, Marcin, Flisiak, Robert“…The aim of this study was to assess the co-incidence of cirrhosis, alcohol abuse, hepatitis B virus (HBV) or hepatitis C virus (HCV) infection and fatty liver disease in patients in the population of north-eastern Poland, to analyse the usefulness of α-fetoprotein (AFP) in the diagnosis of HCC and to assess the effectiveness of HCC treatment in this group. …”
Publicado 2021
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12015por Massavirov, Sherali, Akopyan, Kristina, Abdugapparov, Fazlkhan, Ciobanu, Ana, Hovhanessyan, Arax, Khodjaeva, Mavluda, Gadoev, Jamshid, Parpieva, Nargiza“…Having extrapulmonary TB (aOR 2.21, 95% CI: 1.38–3.53, p = 0.001), positive sputum smear laboratory results on admission (aOR 1.62, 95% CI: 1.07–2.40), diabetes (aOR 5.16, 95% CI: 1.77–14.98), and hepatitis C (aOR 1.68, 95% CI: 1.14–2.46) were independent risk factors for developing unfavorable TB treatment outcomes. …”
Publicado 2021
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12016por Zahr, Natalie M., Pohl, Kilian M., Kwong, Allison J., Sullivan, Edith V., Pfefferbaum, Adolf“…In testing this proposal, previous work included a group of human immunodeficiency virus (HIV)-infected individuals as positive controls and identified elevations in the soluble proteins TNFα and IP10; these cytokines were only elevated in AUD individuals seropositive for hepatitis C infection (HCV). The current observational, cross-sectional study evaluated whether higher levels of these proinflammatory cytokines would be associated with compromised brain integrity. …”
Publicado 2021
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12017por Komiyama, Seiga, Yamada, Takahiro, Takemura, Nobuyuki, Kokudo, Norihiro, Hase, Koji, Kawamura, Yuki I.“…Additionally, we identified Ruminococcus gnavus as a signature taxon for HCC patients infected with hepatitis B and/or hepatitis C viruses. This study suggests that tumour microbiota may contribute to the pathology of HCC.…”
Publicado 2021
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12018“…Intriguingly, the knockdown of HSPA6 also caused the reduction of luciferase activity driven by the IRES from coxsackievirus A16, echovirus 9, encephalomyocarditis virus, or hepatitis C virus, supporting that HSPA6 may assist the function of a cellular protein generally required for viral IRES activities.…”
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12019por Rahman, Shah Kamranur, Ansari, Mairaj Ahmed, Gaur, Pratibha, Ahmad, Imtiyaz, Chakravarty, Chandrani, Verma, Dileep Kumar, Sharma, Anshika, Chhibber, Sanjay, Nehal, Naila, Wirth, Dagmar, Lal, Sunil K.“…We found that CD66c is a specific glycoprotein receptor for influenza A virus that did not affect entry of non-IAV RNA virus (Hepatitis C virus). Finally, IAV pre-incubated with recombinant CD66c protein when administered intranasally in mice showed decreased cytopathic effects in mice lungs. …”
Publicado 2021
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12020por Vallianou, Natalia G., Tsilingiris, Dimitrios, Christodoulatos, Gerasimos Socrates, Karampela, Ιrene, Dalamaga, Maria“…Remdesivir (GS-5734), a drug initially developed to treat hepatitis C and Ebola virus disease, was the first approved treatment for severe coronavirus disease 2019 (COVID-19). …”
Publicado 2021
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