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12301por Manzoor, Sobia, Idrees, Muhammad, Ashraf, Javed, Mehmood, Azra, Butt, Sadia, Fatima, Kaneez, Akbar, Haji, Rehaman, Irshad U, Qadri, Ishtiaq“…Hepatitis C virus (HCV) is a major health problem in developing countries including Pakistan. …”
Publicado 2011
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12302por Balabanova, Yanina, Gilsdorf, Andreas, Buda, Silke, Burger, Reinhard, Eckmanns, Tim, Gärtner, Barbara, Groß, Uwe, Haas, Walter, Hamouda, Osamah, Hübner, Johannes, Jänisch, Thomas, Kist, Manfred, Kramer, Michael H., Ledig, Thomas, Mielke, Martin, Pulz, Matthias, Stark, Klaus, Suttorp, Norbert, Ulbrich, Uta, Wichmann, Ole, Krause, Gérard“…Twenty-six pathogens were ranked in the highest priority group; among those were pathogens with internationally recognised importance (e.g., Human Immunodeficiency Virus, Mycobacterium tuberculosis, Influenza virus, Hepatitis C virus, Neisseria meningitides), pathogens frequently causing large outbreaks (e.g., Campylobacter spp.), and nosocomial pathogens associated with antimicrobial resistance. …”
Publicado 2011
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12303por Dias, Paulo Telles, Hahn, Judith A, Delwart, Eric, Edlin, Brian, Martin, Jeff, Lum, Paula, Evans, Jennifer, Kral, Alex, Deeks, Steve, Busch, Michael P, Page, Kimberly“…BACKGROUND: Hepatitis C virus (HCV) genotype (GT) has become an important measure in the diagnosis and monitoring of HCV infection treatment. …”
Publicado 2011
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12304por Lim, Pei-Yin, Keating, Julie A., Hoover, Spencer, Striker, Rob, Bernard, Kristen A.“…We have previously shown that a thiopurine drug, 6-methylmercaptopurine riboside (6MMPr), inhibits replication of distantly related viruses within the Flaviviridae family in cell culture, including bovine viral diarrhea virus and hepatitis C virus replicon. Here we further examined the potential antiviral effect of 6MMPr on several diverse flaviviruses. …”
Publicado 2011
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12305por Wang, Jia, Kou, Huijuan, Fu, Qiang, Han, Yang, Qiu, Zhifeng, Zuo, Lingyan, Li, Yanling, Zhu, Zhu, Ye, Min, Ma, Qing, Li, Taisheng“…Hepatotoxicity was significantly associated with the median nevirapine trough concentrations among male patients (8.20 vs. 5.48 µg/ml, p = 0.015) and hepatitis C virus co-infection (p = 0.039). CONCLUSIONS: Among Chinese patients with HIV infection, the therapeutic C(trough) of nevirapine was 3.9 µg/ml, higher than the recommended 3.0 µg/ml. …”
Publicado 2011
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12306por Mir-Nasseri, Mohammad Mehdi, MohammadKhani, Ashraf, Tavakkoli, Hamid, Ansari, Esmaeil, Poustchi, Hossein“…BACKGROUND: There is a strong association between hepatitis B virus (HBV), hepatitis C virus (HCV) and human immunodeficiency virus (HIV) infection which are mainly transmitted by contamination with blood via intravenous drug abuse (IVDU) or sexual contact. …”
Publicado 2011
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12307por Sumie, Shuji, Kawaguchi, Takumi, Kuromatsu, Ryoko, Takata, Akio, Nakano, Masahito, Satani, Manabu, Yamada, Shingo, Niizeki, Takashi, Torimura, Takuji, Sata, Michio“…We evaluated whether adiponectin level was associated with the prevalence and histological grade of hepatocellular carcinoma (HCC), and liver fibrosis in patients with hepatitis C virus (HCV) infection. METHODS: A case-control study was conducted on 97 HCC patients (cases) and 97 patients (controls) matched for sex, Child-Pugh grade and platelet count in patients with HCV infection. …”
Publicado 2011
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12308por Etoh, Reiko, Imazeki, Fumio, Kurihara, Tomoko, Fukai, Kenichi, Fujiwara, Keiichi, Arai, Makoto, Kanda, Tatsuo, Mikata, Rintaro, Yonemitsu, Yutaka, Yokosuka, Osamu“…BACKGROUND: Pegylated (PEG)-interferon (IFN)-alfa-2a plus ribavirin (RBV) therapy for 24 weeks is now a standard treatment protocol for patients with hepatitis C virus (HCV) genotype 2. As RBV cannot be used in certain situations, we examined whether PEG-IFN-alfa-2a monotherapy for 24 weeks or less would be sufficient to obtain a sustained virological response (SVR) in patients infected with HCV genotype 2. …”
Publicado 2011
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12309por Kozyreva, Olga N., Chi, Dorcas, Clark, Jeffrey W., Wang, Hejing, Theall, Kathy P., Ryan, David P., Zhu, Andrew X.“…The male/female (M/F) ratio was 5.8:1 and 1.7:1 in the younger and elderly groups, respectively (p < .0001). Hepatitis C virus (HCV) infection rate was 48.3% in younger and 21.1% in elderly patients (p < .0001); Child class B and C cirrhosis accounted for 35.8% in younger and 25.3% in elderly patients (p = .063). …”
Publicado 2011
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12310por Larsen, Christine, Chaix, Marie-Laure, Le Strat, Yann, Velter, Annie, Gervais, Anne, Aupérin, Isabelle, Alric, Laurent, Duval, Xavier, Miailhes, Patrick, Pioche, Corinne, Pol, Stanislas, Piroth, Lionel, Delarocque-Astagneau, Elisabeth“…OBJECTIVES: The HEPAIG study was conducted to better understand Hepatitis C virus (HCV) transmission among human immuno-deficiency (HIV)-infected men who have sex with men (MSM) and assess incidence of HCV infection among this population in France. …”
Publicado 2011
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12311por Dimitroulopoulos, Dimitrios, Elefsiniotis, Ioannis, Pavlidis, Christos, Xinopoulos, Dimitrios, Tsamakidis, Klisthenis, Patsavela, Stamatina, Kypreos, Dimitrios, Ferderigou, Ageliki, Korkolis, Dimitrios, Koutsounas, Sotirios, Saroglou, Georgios, Paraskevas, Emmanouil“…BACKGROUND AND AIMS: Despite the recent spread of hepatitis C virus genotype 4 (HCV-4) into European countries, very little is known about the influence of ethnicity on treatment outcomes in patients with HCV-4. …”
Publicado 2010
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12312“…BACKGROUND AND AIMS: To compare several non-invasive methods of fibrosis assessment in chronic hepatitis C virus (HCV) infection (platelet count, the APRI score, the Forns score, the Lok score, FIB-4, Transient Elastography [TE]), versus percutaneous liver biopsy (LB). …”
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12313por de Castellarnau, Montserrat, Aparicio, Ester, Parera, Mariona, Franco, Sandra, Tural, Cristina, Clotet, Bonaventura, Martínez, Miguel Angel“…We genotyped eight IL28B single-nucleotide polymorphisms (SNPs) in a cohort of 197 hepatitis C virus (HCV)/human immunodeficiency virus type 1 (HIV-1) coinfected patients from our clinic unit who received combined pegylated (peg)-IFN-α and ribavirin (RBV) therapy. …”
Publicado 2012
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12314por Asad, Sultan, Ijaz, Bushra, Ahmad, Waqar, Kausar, Humera, Sarwar, Muhammad Tahir, Gull, Sana, Shahid, Imran, Khan, Muhammad Kazim, Hassan, Sajida“…BACKGROUND: Hepatitis C virus (HCV) is one of the major health concerns globally, with genotype 3a as the most prevalent in Pakistan. …”
Publicado 2012
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12315por Zhou, Jialun, Tanuma, Junko, Chaiwarith, Romanee, Lee, Christopher K. C., Law, Matthew G., Kumarasamy, Nagalingeswaran, Phanuphak, Praphan, Chen, Yi-Ming A., Kiertiburanakul, Sasisopin, Zhang, Fujie, Vonthanak, Saphonn, Ditangco, Rossana, Pujari, Sanjay, Choi, Jun Yong, Parwati Merati, Tuti, Yunihastuti, Evy, Li, Patrick C. K., Kamarulzaman, Adeeba, Nguyen, Van Kinh, Thuy Pham, Thi Thanh, Lim, Poh Lian“…These patients were more likely to have low or missing haemoglobin (P < 0.001), missing recent HIV viral load (P < 0.001), negative hepatitis C test (P = 0.025), and previous temporary LTFU episodes (P < 0.001). …”
Publicado 2012
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12316por Strnad, Pavel, Kucukoglu, Ozlem, Lunova, Mariia, Guldiken, Nurdan, Lienau, Tim C., Stickel, Felix, Omary, M. Bishr“…Exonic K8/K18 variants associate with adverse outcome in acute liver failure and with liver fibrosis progression in patients with chronic hepatitis C infection or primary biliary cirrhosis. …”
Publicado 2012
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12317por Halfon, Philippe, Ouzan, Denis, Khiri, Hacène, Pénaranda, Guillaume, Castellani, Paul, Oulès, Valerie, Kahloun, Asma, Amrani, Nolwenn, Fanteria, Lise, Martineau, Agnès, Naldi, Lou, Bourlière, Marc“…BACKGROUND & AIMS: Point mutations in the coding region of the interleukin 28 gene (rs12979860) have recently been identified for predicting the outcome of treatment of hepatitis C virus infection. This polymorphism detection was based on whole blood DNA extraction. …”
Publicado 2012
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12318por Patel, Maulik R., Loo, Yueh-Ming, Horner, Stacy M., Gale, Michael, Malik, Harmit S.“…We focused on how this positive selection has shaped MAVS' susceptibility to Hepatitis C virus (HCV). We functionally tested MAVS proteins from diverse primate species for their ability to resist antagonism by HCV, which uses its protease NS3/4A to cleave human MAVS. …”
Publicado 2012
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12319“…Five patients (26.3%) had contracted transfusion-transmitted viral infections – 21.1% and 5.3% respectively had antibodies to hepatitis C virus and HIV, while 5.3% were positive for Australia antigen. …”
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12320“…BACKGROUND: Although primary and established human hepatoma cell lines have been evaluated for hepatitis C virus (HCV) infection in vitro, thus far only Huh7 cells have been found to be highly permissive for infectious HCV. …”
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