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12461por Amoras, Ednelza da Silva Graça, Gomes, Samara Tatielle Monteiro, Freitas, Felipe Bonfim, Santana, Bárbara Brasil, Ishak, Geraldo, de Araújo, Marialva Tereza Ferreira, Demachki, Sâmia, da Silva Conde, Simone Regina Souza, de Oliveira Guimarães Ishak, Marluísa, Ishak, Ricardo, Vallinoto, Antonio Carlos Rosário“…Fifty-one liver biopsy specimens obtained from patients with hepatitis B virus (n = 6), hepatitis C virus (n = 28), and non-viral hepatitis – (n = 9) and standard histological liver (n = 8) as controls (CT) were subjected to qPCR and histopathological exams. …”
Publicado 2015
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12462por Qiu, Ping, Stevens, Richard, Wei, Bo, Lahser, Fred, Howe, Anita Y. M., Klappenbach, Joel A., Marton, Matthew J.“…Genotyping of hepatitis C virus (HCV) plays an important role in the treatment of HCV. …”
Publicado 2015
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12463por Tietjen, Ian, Ntie-Kang, Fidele, Mwimanzi, Philip, Onguéné, Pascal Amoa, Scull, Margaret A., Idowu, Thomas Oyebode, Ogundaini, Abiodun Oguntuga, Meva’a, Luc Mbaze, Abegaz, Berhanu M., Rice, Charles M., Andrae-Marobela, Kerstin, Brockman, Mark A., Brumme, Zabrina L., Fedida, David“…Both ixoratannin A-2 and boldine also inhibited in vitro replication of hepatitis C virus (HCV). However, BIT-225, a previously-reported Vpu inhibitor, demonstrated antiviral activity but also cytotoxicity in HIV-1 and HCV replication assays. …”
Publicado 2015
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12464por Strating, Jeroen R.P.M., van der Linden, Lonneke, Albulescu, Lucian, Bigay, Joëlle, Arita, Minetaro, Delang, Leen, Leyssen, Pieter, van der Schaar, Hilde M., Lanke, Kjerstin H.W., Thibaut, Hendrik Jan, Ulferts, Rachel, Drin, Guillaume, Schlinck, Nina, Wubbolts, Richard W., Sever, Navdar, Head, Sarah A., Liu, Jun O., Beachy, Philip A., De Matteis, Maria A., Shair, Matthew D., Olkkonen, Vesa M., Neyts, Johan, van Kuppeveld, Frank J.M.“…ITZ binds OSBP and inhibits its function, i.e., shuttling of cholesterol and phosphatidylinositol-4-phosphate between membranes, thereby likely perturbing the virus-induced membrane alterations essential for viral replication organelle formation. ITZ also inhibits hepatitis C virus replication, which also relies on OSBP. …”
Publicado 2015
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12465por Orlova, O. V., Drutsa, V. L., Spirin, P. V., Prasolov, V. S., Rubtsov, P. M., Kochetkov, S. N., Beljelarskaya, S. N.“…The hepatitis C virus (HCV) envelope proteins E1 and E2, being virion components, are involved in the formation of infectious particles in infected cells. …”
Publicado 2015
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12466por Trussoni, Christy E., Tabibian, James H., Splinter, Patrick L., O’Hara, Steven P.“…Immunofluorescence for phospho-EGFR was performed on LPS-treated mouse samples and specimens from patients with primary sclerosing cholangitis, primary biliary cirrhosis, hepatitis C, and normal livers. LPS-treatment induced an association between the TLR/MyD88 and EGFR/Grb2 signaling apparatus, NRas activation, and EGFR phosphorylation. …”
Publicado 2015
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12467por Kawahara, Ai, Tsukada, Junichi, Yamaguchi, Takahiro, Katsuragi, Takefumi, Higashi, Takehiro“…Primary hepatic lymphoma (PHL) is an extremely rare disease, frequently associated with viruses such as hepatitis B virus (HBV), hepatitis C virus (HCV), and human immune deficiency virus (HIV). …”
Publicado 2015
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12468por Moon, Hyung Hwan, Kim, Tae-seok, Lee, Sanghoon, Song, Sanghyun, Shin, Milljae, Park, Jae Berm, Kim, Jong Man, Jang, Hye Ryoun, Huh, Wooseong, Joh, Jae-Won, Kim, Sung Joo“…The criteria of inclusion were living donor kidney transplantation (KT), no evidence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection, and PRA less than 50%. …”
Publicado 2014
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12469“…Subgroup analysis by ethnicity and disease implicated that high serum CK-18 levels might be a risk factor for non-alcoholic steatohepatitis (NASH), chronic hepatitis C (CHC), and chronic hepatitis B (CHB) (all P < 0.05) among Asians (SMD = 2.89, 95%CI: 2.35-3.43, P < 0.001), Africans (SMD = 0.69, 95%CI: 0.12-1.26, P = 0.017), and Caucasians (SMD = 4.86, 95%CI: 1.82-7.89, P = 0.002). …”
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12470“…We studied the knowledge and risk factors associated with barbers’ occupation in the transmission of hepatitis B virus (HBV) and hepatitis C virus (HCV). METHODS: A randomized cross-sectional survey of 200 barbershops was conducted in Kumasi between January and August 2013. …”
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12471“…Such a pronounced co-localization of disulphide bridges and N-glycans was also found for the N-glycans on glycoprotein E1 of the hepatitis C virus (HCV) but not for other heavily glycosylated proteins such as E2 from HCV and the surface GP from Ebola virus. …”
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12472“…GENERAL SIGNIFICANCE: Peptidyl-prolyl isomerase inhibitors have been used in clinical trials to validate cyclophilins as antiviral targets for the treatment of HIV-1 and Chronic Hepatitis C virus infection and as molecular probes to identify the roles played by immunophilins in supporting the replication cycles of human viruses. …”
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12473por Wang, Zhao, Ceniccola, Kristin, Florea, Liliana, Wang, Bi-Dar, Lee, Norman H., Kumar, Ajit“…BACKGROUND: Hepatitis C virus (HCV) infection is an established cause of chronic hepatitis, cirrhosis and hepatocellular carcinoma (HCC); however, it is unclear if the virus plays a direct role in the development of HCC. …”
Publicado 2015
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12474“…METHODS: This retrospective chart review evaluated baseline characteristics and follow-up safety and tolerability data for patients with hepatitis C virus (HCV) infection treated with telaprevir and peginterferon alfa and ribavirin (PR) in clinical practice. …”
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12475por Duong, Cuong Minh, Olszyna, Dariusz Piotr, Nguyen, Phong Duy, McLaws, Mary-Louise“…METHODS: One hundred forty-two patients were tested for hepatitis B virus (HBV) surface antigen and hepatitis C virus (HCV) core antigen. They provided demographic, medical and dialysis information. …”
Publicado 2015
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12476por Kassaye, Seble, Li, Ying, Huhn, Gregory, Peters, Marion G, French, Audrey L, Tien, Phyllis C, Luxon, Bruce, Plankey, Michael W“…OBJECTIVE: The aim of this study was to determine the test characteristics of direct and indirect biomarkers for liver fibrosis compared with transient elastography (TE) among a group of human immunodeficiency virus (HIV)-infected and uninfected women with or without Hepatitis C virus (HCV) infection. METHODS: Women enrolled in the Women’s Interagency HIV Study (WIHS) from Washington DC, San Francisco, and Chicago with a body mass index (BMI)<35 underwent liver stiffness measurement using TE between October, 2010 and September, 2012. …”
Publicado 2015
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12477por Cho, Ho Jun, Dong, Seok Ho, Lee, Myung Suk, Kim, Hak Yang, Park, Choong Kee, Yoo, Jae Young, Polito, Allan, Quan, Stella, Han, Jang Hyun“…To evaluate the efficacy of interferon and to observe the changes of serum aminotransferase (ALT), antibody to hepatitis C virus (anti-HCV) and HCV ribonucleic acid (HCV-RNA), we treated 10 patients with chronic type C hepatitis for 6 months. …”
Publicado 1992
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12478por Federico, Alessandro, Masarone, Mario, Romano, Marco, Dallio, Marcello, Rosato, Valerio, Persico, Marcello“…BACKGROUND: Standard [i.e. pegylated interferon (Peg-IFN) + ribavirin] treatment of hepatitis C virus (HCV)-related chronic hepatitis is associated with a sustained virological response (SVR) in 50 - 90% of patients. …”
Publicado 2015
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12479por You, Hong, Liu, Sandu, Xie, Yong, Cong, Rui, Sun, Yameng, Ren, Jingjing, Wei, Kangfei, Jin, Xin, Shi, Yujian, Zhang, Haiying, Li, Jie, Wei, Lai, Zhuang, Hui, Cheng, Mingliang, Jia, Jidong“…BACKGROUND AND AIMS: A total of 105 patients were identified as accidentally infected with hepatitis C virus genotype 1b (HCV1b) through blood transfusion from a single blood donor. …”
Publicado 2015
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12480por Strassl, Robert, Rutter, Karoline, Stättermayer, Albert Friedrich, Beinhardt, Sandra, Kammer, Michael, Hofer, Harald, Ferenci, Peter, Popow-Kraupp, Theresia“…BACKGROUND AND AIMS: Monitoring of chronic Hepatitis C (CHC) treatment relies on HCV RNA quantification by means of real-time PCR methods. …”
Publicado 2015
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