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12841por Adachi, Yuki, Hayashi, Hiromitsu, Yusa, Toshihiko, Takematsu, Toru, Matsumura, Kazuki, Higashi, Takaaki, Yamamura, Kensuke, Yamao, Takanobu, Imai, Katsunori, Yamashita, Yo−ichi, Baba, Hideo“…CASE SUMMARY: A retroperitoneal tumor (6 cm) was located at the dorsal side of the pancreas head on abdominal ultrasonography in an 81-year old woman positive for hepatitis C virus antibody. Contrast enhanced-computed tomography and gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging showed viable HCC patterns with early enhancement and delayed washout. …”
Publicado 2020
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12842por Lozanovski, Vladimir J., Döhler, Bernd, Weiss, Karl Heinz, Mehrabi, Arianeb, Süsal, Caner“…The impact of CIT was strongest in patients with hepatitis C-related (HCV) cirrhosis with a 24% higher risk of graft loss already at 8–9 h (HR 1.24, 95% CI 1.05–1.47, P = 0.011) and 64% higher risk at ≥14 h (HR 1.64, 95% CI 1.30–2.09, P < 0.001). …”
Publicado 2020
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12843“…Previously, a telomerase-derived 16-mer peptide, GV1001, developed as an anticancer vaccine, was reported to exert antiviral effects on human immunodeficiency virus or hepatitis C virus in a heat shock protein-dependent manner. …”
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12844por Jepkemei, Kiptoon Beatrice, Ochwoto, Missiani, Swidinsky, Ken, Day, Jacqueline, Gebrebrhan, Henok, McKinnon, Lyle R., Andonov, Anton, Oyugi, Julius, Kimani, Joshua, Gachara, George, Songok, Elijah Maritim, Osiowy, Carla“…Positive DNA samples were sequenced and MSM-SW patients were further tested for hepatitis C virus (HCV) infection. Of the 166 HBsAg-negative samples tested, 31 (18.7%; 95% confidence interval [CI] 13.5–25.3) were HBV DNA positive (i.e., occult), the majority (20/31; 64.5%) of which were HBV core protein antibody positive. …”
Publicado 2020
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12845por Aby, Elizabeth S., Winters, Adam C., Lin, Jonathan, Bui, Aileen, Kawamoto, Jenna, Goetz, Matthew B., Bhattacharya, Debika, Pisegna, Joseph R., May, Folasade P., Patel, Arpan A., Benhammou, Jihane N.“…The most common etiology for cirrhosis was hepatitis C (64.3%), and most of the patients had compensated cirrhosis (68.2%). …”
Publicado 2020
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12846por Sego, T.J., Aponte-Serrano, Josua O., Gianlupi, Juliano Ferrari, Heaps, Samuel R., Breithaupt, Kira, Brusch, Lutz, Crawshaw, Jessica, Osborne, James M., Quardokus, Ellen M., Plemper, Richard K., Glazier, James A.“…We illustrate how to extend the platform to model specific virus types (e.g., hepatitis C) and add additional cellular mechanisms (tissue recovery and variable cell susceptibility to infection), using our software modules and publicly-available software repository.…”
Publicado 2020
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12847“…Methionine adenosyltransferase 2B (MAT2B) and acireductone dioxygenase 1 (ADI1), which regulate HCC development and hepatitis C virus infection, respectively, were among the top 10 HCCPMs predicted by dBMHCC. …”
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12848por Osawa, Leona, Tamaki, Nobuharu, Kurosaki, Masayuki, Kirino, Sakura, Watakabe, Keiya, Wang, Wan, Okada, Mao, Shimizu, Takao, Higuchi, Mayu, Takaura, Kenta, Takada, Hitomi, Kaneko, Shun, Yasui, Yutaka, Tsuchiya, Kaoru, Nakanishi, Hiroyuki, Itakura, Jun, Takahashi, Yuka, Enomoto, Nobuyuki, Izumi, Namiki“…In this study, we examined whether serum markers after 1 year of SVR could predict subsequent HCC development. Total 734 chronic hepatitis C patients without a history of HCC who achieved SVR with direct-acting antivirals were included. …”
Publicado 2020
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12849por Elhendawy, Mohammed, Abo-Ali, Lobna, Abd-Elsalam, Sherief, Hagras, Maha M., Kabbash, Ibrahim, Mansour, Loai, Atia, Sherief, Esmat, Gamal, Abo-ElAzm, Abdel-Raouf, El-Kalla, Ferial, Kobtan, Abdelrahman“…The highest recorded hepatitis C virus (HCV) prevalence worldwide is in Egypt. …”
Publicado 2020
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12850por Vatsalya, Vatsalya, Agrawal, Ruchita, Frimodig, Jane, Srivastava, Shweta, Schwandt, Melanie L.“…Alcohol use disorder (AUD) patients comorbid with hepatitis C virus (HCV) infection (HCV + AUD) could have progressively severe clinical sequels of liver injury and inflammation. …”
Publicado 2020
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12851por Hanke, Kirsten, Fiedler, Stefan, Grumann, Christina, Ratmann, Oliver, Hauser, Andrea, Klink, Patrycja, Meixenberger, Karolin, Altmann, Britta, Zimmermann, Ruth, Marcus, Ulrich, Bremer, Viviane, Auwärter, Volker, Bannert, Norbert“…For selected samples, the hepatitis C virus (HCV) status and the presence of NPS were determined. …”
Publicado 2020
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12852por Tal, Michal Caspi, Torrez Dulgeroff, Laughing Bear, Myers, Lara, Cham, Lamin B., Mayer-Barber, Katrin D., Bohrer, Andrea C., Castro, Ehydel, Yiu, Ying Ying, Lopez Angel, Cesar, Pham, Ed, Carmody, Aaron B., Messer, Ronald J., Gars, Eric, Kortmann, Jens, Markovic, Maxim, Hasenkrug, Michaela, Peterson, Karin E., Winkler, Clayton W., Woods, Tyson A., Hansen, Paige, Galloway, Sarah, Wagh, Dhananjay, Fram, Benjamin J., Nguyen, Thai, Corey, Daniel, Kalluru, Raja Sab, Banaei, Niaz, Rajadas, Jayakumar, Monack, Denise M., Ahmed, Aijaz, Sahoo, Debashis, Davis, Mark M., Glenn, Jeffrey S., Adomati, Tom, Lang, Karl S., Weissman, Irving L., Hasenkrug, Kim J.“…Furthermore, proinflammatory cytokines, including those found in the plasma of hepatitis C patients, upregulated CD47 on uninfected dendritic cells, thereby linking innate modulation with downstream adaptive immune responses. …”
Publicado 2020
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12853por Abu-Zaied, Mamdouh Attia, Hammad, Sherif F., Halaweish, Fathi T., Elgemeie, Galal Hamza“…Eight compounds were evaluated for their antiviral activities against different viral cell lines, namely, adenovirus 7, HAV (hepatitis A) HM175, Coxsackievirus B4, and HSV-1 (herpes simplex virus type 1), in addition to the antiviral bioassay against ED-43/SG-Feo (VYG) replicon of HCV (hepatitis C virus) genotype 4a. Both compounds 5b and 11 showed notable antiviral activity against Coxsackie virus B4, reflected from the CC(50) values of 17 and 20 μg/100 μL and IC(50) values of 4.5 and 6.0 μg/100 μL, respectively. …”
Publicado 2020
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12854por Duracinsky, Martin, Thonon, Frédérique, Bun, Sonia, Ben Nasr, Imène, Dara, Aïchata Fofana, Lakhdari, Sabrina, Coblentz-Baumann, Laurence, Lert, France, Dimi, Svetlane, Chassany, Olivier“…INTRODUCTION: The prevalence of HIV, hepatitis B, and hepatitis C amongst migrants in France is high. Thus, effective screening and follow-up is needed. …”
Publicado 2020
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12855por Colodette, Natalie M., Franco, Lucas S., Maia, Rodolfo C., Fokoue, Harold H., Sant’Anna, Carlos Mauricio R., Barreiro, Eliezer J.“…In this work it is presented a virtual screening methodology combining a pharmacophore-based model and an empirical Gibbs free energy-based model for the ligand–protein interaction to explore the LASSBio Chemical Library as a source of new hits for the inhibition of the phosphatidylinositol 4-kinase IIIβ (PI4KIIIβ) enzyme, which is related to the development of viral infections (including enteroviruses, SARS coronavirus, and hepatitis C virus), cancers and neurological diseases. …”
Publicado 2020
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12856“…Some of the risk factors for the development of HCC include Hepatitis B virus (HBV), Hepatitis C virus (HCV), chronic alcoholism, autoimmune hepatitis, among others. …”
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12857por Aly, Doaa Mamdouh, Gohar, Nadida Abdul- Hameed, Abd El-Hady, Afaf Ahmed, Khairy, Marwa, Abdullatif, Mona Mohsen“…BACKGROUND: Egypt has the highest prevalence of hepatitis C virus (HCV) worldwide. Which make liver cirrhosis and hepatocellular carcinoma (HCC) major health concerns in Egypt. …”
Publicado 2020
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12858“…The E2 envelope glycoprotein of the hepatitis C virus (HCV) is a major target of broadly neutralizing antibodies that are closely related to a spontaneous cure of HCV infection. …”
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12859por Hirata, Yuta, Sanada, Yukihiro, Omameuda, Takahiko, Katano, Takumi, Miyahara, Go, Yamada, Naoya, Okada, Noriki, Onishi, Yasuharu, Sakuma, Yasunaru, Sata, Naohiro“…CASE PRESENTATION: The patient was a 57-year-old man who had been diagnosed with decompensate liver cirrhosis by hepatitis C virus infection. He presented with repeated hepatic coma and refractory ascites. …”
Publicado 2020
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12860por Tatemichi, Masayuki, Furuya, Hiroyuki, Nagahama, Satsue, Takaya, Norihide, Shida, Yukari, Fukai, Kota, Owada, Satoshi, Endo, Hitoshi, Kinoue, Takaaki, Korenaga, Masaaki“…In Japan, there is no publicly funded screening for hepatitis B virus (HBV) and hepatitis C virus (HCV) infections (using HBs antigen and HCV antibody, respectively) among workers, and workplace health programmes play a crucial role in reducing viral hepatitis-related deaths. …”
Publicado 2020
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