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13141por Ayorinde, Abimbola, Ghosh, Iman, Ali, Ifra, Zahair, Iram, Olarewaju, Olajumoke, Singh, Megha, Meehan, Edward, Anjorin, Seun Stephen, Rotheram, Suzanne, Barr, Ben, McCarthy, Noel, Oyebode, Oyinlola“…Our search focused on tuberculosis, HIV, sexually transmitted infections, hepatitis C, vaccination and antimicrobial resistance. …”
Publicado 2023
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13142por Origa, Raffaella, Gianesin, Barbara, Longo, Filomena, Di Maggio, Rosario, Cassinerio, Elena, Gamberini, Maria Rita, Pinto, Valeria Maria, Quarta, Antonella, Casale, Maddalena, La Nasa, Giorgio, Caocci, Giovanni, Piroddi, Antonio, Piolatto, Andrea, Di Mauro, Alessandra, Romano, Claudia, Gigante, Antonia, Barella, Susanna, Maggio, Aurelio, Graziadei, Giovanna, Perrotta, Silverio, Forni, Gian Luca“…HCC has been confirmed as the most frequent tumor, but advances in chelation and the drugs that have led to the eradication of hepatitis C may explain the recent steadiness in the number of diagnoses that is reported here.…”
Publicado 2022
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13143por Lucey, Olivia, Acana, Susan, Olupot‐Olupot, Peter, Muhindo, Rita, Ayikobua, Ronald, Uyoga, Sophie, Kyeyune‐Byabazaire, Dorothy, Cooke, Graham, Maitland, Kathryn“…We aimed to ascertain the false discovery rate of the Architect anti‐hepatitis C virus (HCV) screening assay and categorize screen‐reactive samples into three groups: presumed false positive, active and past infection, and develop an algorithm for confirmatory testing. …”
Publicado 2022
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13144por Zitzmann, Carolin, Dächert, Christopher, Schmid, Bianca, van der Schaar, Hilde, van Hemert, Martijn, Perelson, Alan S., van Kuppeveld, Frank J. M., Bartenschlager, Ralf, Binder, Marco, Kaderali, Lars“…We first measured the kinetics of viral RNA, viral protein, and infectious virus particle production of hepatitis C virus (HCV), dengue virus (DENV), and coxsackievirus B3 (CVB3) in the immuno-compromised Huh7 cell line and thus without perturbations by an intrinsic immune response. …”
Publicado 2023
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13145por Howell, Jess, Majumdar, Avik, Fink, Michael, Byrne, Mandy, McCaughan, Geoff, Strasser, Simone I., Crawford, Michael, Hodgkinson, Peter, Stuart, Katherine A., Tallis, Caroline, Chen, John, Wigg, Alan, Jones, Robert, Jaques, Bryon, Jeffrey, Gary, Adams, Leon, Wallace, Michael C., Gane, Ed, Thompson, Alex, Gow, Paul“…A higher proportion of liver transplants for hepatitis B (12% versus 6%), hepatitis C (33% versus 20%), alcohol liver disease (23% versus 13%), and metabolic-associated fatty liver disease (11% versus 8%, all P < 0.001) were identified when all indications were included than with primary diagnosis only. …”
Publicado 2022
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13146por Choi, Sungchul, Kim, Beom Kyung, Yon, Dong Keon, Lee, Seung Won, Lee, Han Gyeol, Chang, Ho Hyeok, Park, Seoyeon, Koyanagi, Ai, Jacob, Louis, Dragioti, Elena, Radua, Joaquim, Shin, Jae Il, Kim, Seung Up, Smith, Lee“…Hepatitis B virus (HBV) remains the leading cause of liver cancer DALYs and mortality, followed by hepatitis C virus (HCV), alcohol consumption, and non-alcoholic steatohepatitis/non-alcoholic fatty liver disease (NASH/NAFLD). …”
Publicado 2023
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13147por Gomes, Diana, Sobolewski, Cyril, Conzelmann, Stéphanie, Schaer, Tifany, Lefai, Etienne, Alfaiate, Dulce, Tseligka, Eirini D., Goossens, Nicolas, Tapparel, Caroline, Negro, Francesco, Foti, Michelangelo, Clément, Sophie“…Chronic hepatitis C (CHC) is associated with the development of metabolic disorders, including both hepatic and extra-hepatic insulin resistance (IR). …”
Publicado 2023
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13148por Tajiri, Kazuto, Okada, Kazuhiko, Ito, Hiroyuki, Kawai, Kengo, Kashii, Yoshiro, Tokimitsu, Yoshiharu, Muraishi, Nozomu, Murayama, Aiko, Hayashi, Yuka, Minemura, Masami, Takahara, Terumi, Shimizu, Yukihiro, Yasuda, Ichiro“…BACKGROUND: Thrombocytopenia due to hypersplenism is a major complication of hepatitis C virus (HCV)-associated cirrhosis. HCV eradication improves these complications in some patients, but the long-term effects of HCV eradication on these complications remain unclear, especially in patients treated with direct acting antivirals (DAAs). …”
Publicado 2023
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13149por Perez, Shira, Lavi-Itzkovitz, Anat, Gidoni, Moriah, Domovitz, Tom, Dabour, Roba, Khurana, Ishant, Davidovich, Ateret, Tobar, Ana, Livoff, Alejandro, Solomonov, Evgeny, Maman, Yaakov, El-Osta, Assam, Tsai, Yishan, Yu, Ming-Lung, Stemmer, Salomon M., Haviv, Izhak, Yaari, Gur, Gal-Tanamy, Meital“…BACKGROUND & AIMS: Hepatocellular carcinoma (HCC) is a model of a diverse spectrum of cancers because it is induced by well-known etiologies, mainly hepatitis C virus (HCV) and hepatitis B virus. Here, we aimed to identify HCV-specific mutational signatures and explored the link between the HCV-related regional variation in mutations rates and HCV-induced alterations in genome-wide chromatin organization. …”
Publicado 2023
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13150por Gupta, Harsh Bal, Deshpande, Trupti, Choraria, Nirmal, Patel, Putun, Sethia, Shruti G, Sethia, Soumitra“…No cases of hepatitis B or hepatitis C were found. The most common presenting complaint was fever (90%) and the most common clinical finding was icterus (69.7%). …”
Publicado 2023
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13151“…BACKGROUND: Post-exposure prophylaxis (PEP) for occupational human immunodeficiency virus (HIV) exposure involves the comprehensive measures used to prevent transmission of blood-borne pathogens such as HIV, hepatitis B virus, and hepatitis C virus through various strategies such as first aid, counseling, risk assessment, relevant laboratory investigations with informed consent, the provision of short-term anti-retroviral drugs, and follow-up testing. …”
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13152por Watanabe, Takao, Tokumoto, Yoshio, Joko, Kouji, Michitaka, Kojiro, Horiike, Norio, Tanaka, Yoshinori, Hiraoka, Atsushi, Tada, Fujimasa, Ochi, Hironori, Kisaka, Yoshiyasu, Nakanishi, Seiji, Yagi, Sen, Yamauchi, Kazuhiko, Higashino, Makoto, Hirooka, Kana, Morita, Makoto, Okazaki, Yuki, Yukimoto, Atsushi, Hirooka, Masashi, Abe, Masanori, Hiasa, Yoichi“…A total of 1683 chronic hepatitis C patients without HCC who achieved sustained virological response (SVR) with DAA therapy were split into a training set (999 patients) and a validation set (684 patients). …”
Publicado 2023
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13153por Samarasinghe, Sumudu Rangika, Hoy, Wendy, Jadhao, Sudhir, McMorran, Brendan J., Guchelaar, Henk-Jan, Nagaraj, Shivashankar H.“…We further detected important clinical implications for the drugs involved with cancer pharmacogenomics such as thiopurines and tamoxifen, immunosuppressants like tacrolimus and certain antivirals used in the hepatitis C treatment due to potential differences in their metabolic processing. …”
Publicado 2023
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13154por Tatara, Eric, Lin, Qinyun, Ozik, Jonathan, Kolak, Marynia, Collier, Nicholson, Halpern, Dylan, Anselin, Luc, Dahari, Harel, Boodram, Basmattee, Schneider, John“…Syringe sharing among PWID carries high risk of transmission of serious infections such as hepatitis C and HIV. MOUD resources, such as methadone provider clinics, however, are often unavailable to PWID due to barriers like long travel distance to the nearest methadone provider and the required frequency of clinic visits. …”
Publicado 2023
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13155por Salindri, Argita D., Kipiani, Maia, Lomtadze, Nino, Tukvadze, Nestani, Avaliani, Zaza, Blumberg, Henry M., Masyn, Katherine E., Rothenberg, Richard B., Kempker, Russell R., Magee, Matthew J.“…BACKGROUND: We aimed to determine the relationship between common pre-existing comorbidities in patients with tuberculosis (TB) (including human immunodeficiency virus [HIV], diabetes, and hepatitis C virus [HCV]) with rates of all-cause mortality after TB treatment. …”
Publicado 2023
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13156“…The prevalence of reactive results among healthy donors (n=549) by ELISA/chemiluminescence tests was 3.3 per cent (95% CI: 1.9, 5.2), which included hepatitis B (n=15) and hepatitis C (n=3) cases. Compared to healthy donors, the odds of seropositivity among jaundice-deferred donors was 1.7 (95% CI: 0.8, 3.6), P=0.15. …”
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13157por Collett, Simon, Earnest, Linda, Carrera Montoya, Julio, Edeling, Melissa A., Yap, Ashley, Wong, Chinn Yi, Christiansen, Dale, Roberts, Jason, Mumford, Jamie, Lecouturier, Valerie, Pavot, Vincent, Marco, Sergio, Loi, Joon Keit, Simmons, Cameron, Gulab, Shivali A., Mackenzie, Jason M., Elbourne, Aaron, Ramsland, Paul A., Cameron, Garth, Hans, Dhiraj, Godfrey, Dale I., Torresi, Joseph“…The inclusion of the glycolipid adjuvant, α-galactosylceramide (α-GalCer) in the vaccine formulation led to high levels of natural killer T (NKT) cell stimulation in vitro, and strong antibody and memory CD8(+) T cell responses in vivo, demonstrated with SARS-CoV-2, hepatitis C virus (HCV) and DEN VLPs. This study shows our unique vaccine formulation presents a promising, and much needed, new vaccine platform in the fight against infections caused by enveloped RNA viruses.…”
Publicado 2023
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13158por Bondok, Rania M., Barakat, Lamiaa A., Elsergany, Alyaa R., Mahsoub, Nancy, Ghattas, Maivel H.“…METHOD: DNA sequencing was applied for detection of IFITM3 rs 12252-CC and IFITM3 protein level was measured by ELISA to 50 patients with HCC with cirrhosis and 50 with Hepatitis C virus infection. RESULTS: The obtained results of this study indicated that IFITM3 rs 12252-CC was significantly elevated in HCC group, the codominant model of CC genotype of IFITM3 gene had high association with risk of hepatocellular carcinoma with odd ratio (OR) = 2.70, p = 0.041. …”
Publicado 2023
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13159“…Type 2 diabetes mellitus (T2DM) is associated with chronic hepatitis C virus (HCV) infection, and lncRNAs play an important role in HCV-induced T2DM. …”
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13160por Pietrantoni, Dylan, Barroca, Crystal, Lynch, Sarah, Byrne, Jonathan, Ortner, Miranda, Kotwani, Roshni, Limbrick, Kolin, Kaldas, Paul, Moussa, Michael, Fredrickson, Tatem, Schaefer, Jeffrey, Jacobs, Robin J“…In the United States (U.S.), SSPs have been key in combating the recent opioid use crisis and associated infections such as the human immunodeficiency virus (HIV) and hepatitis C. While some published reports on the pandemic’s overall impacts on SSPs exist, certain aspects such as operational changes and repercussions on staff and participants may still be lacking. …”
Publicado 2023
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