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13421por Ndugga, Nambi, Lightbourne, Teisha G, Javaherian, Kavon, Cabezas, Joaquin, Verma, Neha, Barritt, A Sidney, Bataller, Ramon“…The efficacy rate of current pharmacological agents was 72% for hepatitis B, 89% for hepatitis C, 25% for non-alcoholic steatohepatitis and 13% for alcoholic hepatitis. …”
Publicado 2017
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13422por Kaczmarek, Dominik J., Kokordelis, Pavlos, Krämer, Benjamin, Glässner, Andreas, Wolter, Franziska, Goeser, Felix, Lutz, Philipp, Schwarze-Zander, Carolynne, Boesecke, Christoph, Strassburg, Christian P., Rockstroh, Jürgen K., Spengler, Ulrich, Nattermann, Jacob“…BACKGROUND: A relevant proportion of human immunodeficiency virus (HIV) infected patients is co-infected with the hepatitis C virus (HCV). HCV co-infection in HIV-positive patients is associated with faster progression of liver disease in comparison to HCV mono-infection. …”
Publicado 2017
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13423“…PURPOSE OF REVIEW: Chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections and HIV–HBV and HCV coinfection are major causes of chronic liver disease worldwide. …”
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13424“…BACKGROUND: Pegylated interferon (PegIFN) is used in the treatment of chronic hepatitis C virus (HCV) patients especially in resource limited countries. …”
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13425por Umutesi, Justine, Simmons, Bryony, Makuza, Jean D., Dushimiyimana, Donatha, Mbituyumuremyi, Aimable, Uwimana, Jean Marie, Ford, Nathan, Mills, Edward J., Nsanzimana, Sabin“…We estimated the prevalence of the hepatitis B surface antigen (HBsAg) and hepatitis C antibody (HCVAb) among HIV-infected individuals in Rwanda and identified factors associated with infection. …”
Publicado 2017
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13426“…RESULTS: We identified five primary themes that emerged from the qualitative interviews, including high levels of health insurance enrollment among SEP clients; barriers to enrolling in health insurance; highly needed referrals to services, including improved access to substance use disorder treatment and hepatitis C virus treatment; barriers to referring clients to these highly needed services; and recommendations for policy change. …”
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13427“…We conducted a 12-year population-based cohort study of hepatitis C virus (HCV)-infected patients who were older than 20 years and had received IFN-α therapy. …”
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13428por Völker, Fabian, Cooper, Paul, Bader, Oliver, Uy, Angela, Zimmermann, Ortrud, Lugert, Raimond, Groß, Uwe“…In contrast, infections caused by hepatitis C virus (1.1% anti-HCV) and HIV (0.6%) were rare. …”
Publicado 2017
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13429por de Matos, Marcos André, França, Divânia Dias da Silva, Carneiro, Megmar Aparecida dos Santos, Martins, Regina Maria Bringel, Kerr, Lígia Regina Franco Sansigolo, Caetano, Karlla Antonieta Amorim, Pinheiro, Raquel Silva, de Araújo, Lyriane Apolinário, Mota, Rosa Maria Salani, de Matos, Marcia Alves Dias, Motta-Castro, Ana Rita Coimbra, Teles, Sheila Araújo“…We have detected the subgenotype A1 of hepatitis B virus (n = 3) and the subtypes of hepatitis C virus 1a (n = 3) and 1b (n = 1). CONCLUSIONS: We can observe a low prevalence of infection of hepatitis B and C viruses in the studied population. …”
Publicado 2017
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13430por Shim, Chang Woo, Park, Joong-Won, Kim, So Hee, Kim, Jin Sook, Kim, Bo Hyun, Kim, Sung Hoon, Hong, Eun Kyung“…The prevalence of NCL was 19.2%, 32.5%, 50.0%, and 48.7% among patients with HBV, hepatitis C virus (HCV), alcoholic, and cryptogenic disease, respectively (p < 0.05); corresponding nonfibrosis rates were 8.1%, 0%, 19.0%, and 24.3%, respectively. …”
Publicado 2017
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13431por Raj, V. Stalin, Hundie, Gadissa Bedada, Schürch, Anita C., Smits, Saskia L., Pas, Suzan D., Le Pogam, Sophie, Janssen, Harry L. A., de Knegt, Rob J., Osterhaus, Albert D. M. E., Najera, Isabel, Boucher, Charles A., Haagmans, Bart L.“…Current standard-of-care treatment of chronically infected hepatitis C virus (HCV) patients involves direct-acting antivirals (DAA). …”
Publicado 2017
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13432por Fukuhara, Takasuke, Tamura, Tomokazu, Ono, Chikako, Shiokawa, Mai, Mori, Hiroyuki, Uemura, Kentaro, Yamamoto, Satomi, Kurihara, Takeshi, Okamoto, Toru, Suzuki, Ryosuke, Yoshii, Kentaro, Kurosu, Takeshi, Igarashi, Manabu, Aoki, Hiroshi, Sakoda, Yoshihiro, Matsuura, Yoshiharu“…Amphipathic α-helices of exchangeable apolipoproteins have shown to play crucial roles in the formation of infectious hepatitis C virus (HCV) particles through the interaction with viral particles. …”
Publicado 2017
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13433“…Healthcare workers (HCWs) are at risk of acquiring HBV, hepatitis C (HCV) and human immunodeficiency virus (HIV) infections via exposure to patients’ blood and bodily fluids. …”
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13434“…Overall, the sPrev for each risk factor among Chinese PLWHA was: 41.1% (95% CI: 35.3–46.9%) for current smoking; 30.3% (95% CI: 23.3–37.4%) for current alcohol consumption; 24.4% (95% CI: 14.7–30.2%) for overweight and obesity; 12.5% (95% CI: 10.6–14.3%) for hepatitis B virus infection; 29.1% (95% CI: 23.6–34.5%) for hepatitis C virus infection; 33.9% (95% CI: 24.3–43.5%) for high-risk human papillomavirus infection from cervical samples and 78.6% (95% CI: 69.4–87.7%) from anal samples; 2.7% (95% CI: 0.7–4.7%) for Epstein-Barr virus (EBV) immunoglobulin M (IgM) positivity, 94.7% (95% CI: 90.7–98.8%) for EBV IgG positivity and 25.6% (95% CI: 12.4–38.8%) for EBV DNA positivity; 14.9% (95% CI: 12.4–17.4%) for human herpes virus 8 infection. …”
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13435“…BACKGROUND: Heroin injection is associated with health and social problems including hepatitis C virus (HCV) transmission. Few studies have examined the circumstances surrounding initiation to heroin injecting, especially current users initiating others. …”
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13436por Lu, Mei, Chacra, Wadih, Rabin, David, Rupp, Loralee B, Trudeau, Sheri, Li, Jia, Gordon, Stuart C“…Among 296 patients (23 with hepatitis B, 268 with hepatitis C, and 5 co-infected) with a 2:1 ratio of biopsy-confirmed cirrhosis to noncirrhosis, chart review identified 127 cases of decompensated cirrhosis (Kappa=0.88). …”
Publicado 2017
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13437“…Univariate logistic regression analysis revealed that an age ≥55 years (odds ratio (OR) 2.88, P=0.02), hepatitis C virus (HCV) infection (OR 3.42, P=0.01), and hepatitis activity (OR 4.10, P=0.004) were associated with HHV-8 seropositivity in cirrhotics. …”
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13438por Stelma, Femke, de Niet, Annikki, Sinnige, Marjan J., van Dort, Karel A., van Gisbergen, Klaas P. J. M., Verheij, Joanne, van Leeuwen, Ester M. M., Kootstra, Neeltje A., Reesink, Hendrik W.“…T(RM) can be recognized by CD69 and/or CD103 expression and may play a role in the pathology of chronic hepatitis B (CHB) and hepatitis C virus infection (CHC). Liver and paired blood mononuclear cells from 17 patients (including 4 CHB and 6 CHC patients) were isolated and CD8+ T cells were comprehensively analysed by flowcytometry, immunohistochemistry and qPCR. …”
Publicado 2017
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13439por Chen, Jizheng, Zhang, Zhilei, Wang, Ning, Guo, Min, Chi, Xiumei, Pan, Yu, Jiang, Jing, Niu, Junqi, Ksimu, Sulaiman, Li, John Zhong, Chen, Xinwen, Wang, Qian“…HDAC9 upregulation is involved in hepatitis C virus (HCV)-associated exaggerated gluconeogenesis. …”
Publicado 2017
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13440por Xu, Hong-Tao, Colby-Germinario, Susan P., Hassounah, Said A., Fogarty, Clare, Osman, Nathan, Palanisamy, Navaneethan, Han, Yingshan, Oliveira, Maureen, Quan, Yudong, Wainberg, Mark A.“…We evaluated Sofosbuvir (SOF), the anti-hepatitis C virus prodrug of β-d-2′-deoxy-2′-α-fluoro-2′-β-C-methyluridine-5′-monophosphate, for potential inhibitory activity against DENV replication. …”
Publicado 2017
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