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13481por Su, Shu, Mao, Limin, Zhao, Jinxian, Chen, Liang, Jing, Jun, Cheng, Feng, Zhang, Lei“…The objective of this study is to measure the risk factors for being infected with hepatitis C (HCV), human immunodeficiency virus (HIV) and syphilis among SD-only users, heroin-only users and poly-drug users. …”
Publicado 2018
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13482por Kakuda, Thomas N., McClure, Matthew W., Westland, Christopher, Vuong, Jennifer, Homery, Marie‐Claude, Poizat, Gwendoline, Viguerie, Laure, Denot, Caroline, Patat, Alain, Zhang, Qingling, Hui, James, Apelian, David, Smith, David B., Chanda, Sushmita M., Fry, John“…These data support the further evaluation of this combination for the treatment of chronic hepatitis C virus infection.…”
Publicado 2018
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13483por Choi, Yewon, Yoon, Seonghae, Matsumoto, Kyoko, Ohta, Yoshiyasu, Lee, SeungHwan, Yu, Kyung-Sang, Jang, In-Jin“…INTRODUCTION: Telaprevir, a reversible selective inhibitor of viral protease and a potential blocker of viral replication, is indicated for the treatment of hepatitis C virus genotype 1 infection. In this study, the pharmacokinetic profile, safety, and tolerability of telaprevir and the effect of food on telaprevir exposure were evaluated in healthy Korean subjects, and compared with data from a previous study in Japanese male subjects. …”
Publicado 2018
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13484por Ryom, L, Boesecke, C, Bracchi, M, Ambrosioni, J, Pozniak, A, Arribas, J, Behrens, G, Mallon, PGM, Puoti, M, Rauch, A, Miro, JM, Kirk, O, Marzolini, C, Lundgren, JD, Battegay, M“…Renal and bone toxicity and hepatitis C virus (HCV) treatment have been added as potential reasons for ART switches in fully virologically suppressed individuals, and dolutegravir/rilpivirine has been included as a treatment option. …”
Publicado 2018
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13485“…PURPOSE: Hepatitis C virus (HCV) infection is a major cause of liver disease. …”
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13486por Okoroiwu, Henshaw Uchechi, Okafor, Ifeyinwa Maryann, Asemota, Enosakhare Aiyudubie, Okpokam, Dorathy Chioma“…Sera samples were screened for hepatitis B surface antigen (HBsAg), antibodies to hepatitis C virus (HCV), human immunodeficiency virus (HIV) 1 and 2 and Treponema pallidum using commercially available immunochromatic based kits. …”
Publicado 2018
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13487por Tominaga, Kenta, Uchida, Takahiro, Imakiire, Toshihiko, Itoh, Kenji, Shimazaki, Hideyuki, Nakanishi, Kuniaki, Kumagai, Hiroo, Oshima, Naoki“…However, glomerular PLA(2)R deposits have also been recently observed in several patients with secondary MN, such as hepatitis B virus-associated, hepatitis C virus-associated, and neoplasm-associated MN. …”
Publicado 2018
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13488por Bazi, Ali, Harati, Hadi, Khosravi-Bonjar, Ali, Rakhshani, Elham, Delaramnasab, Mojtaba“…Also, no significant difference was observed between patients with or without HT or HPT regarding the cooccurrence of either diabetes or hepatitis C virus (HCV) infection. In the multivariate analysis, splenectomy remained an independent risk factor for HPT after correction for potential covariates (OR, 6.5; 95% CI, 1 - 39.2; P = 0.04). …”
Publicado 2018
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13489por Vasanthakumar, Aparna, Davis, Justin W., Abunimeh, Manal, Söderholm, Jonas, Zha, Jiuhong, Dumas, Emily O., Cohen, Daniel E., Waring, Jeffrey F., Lagging, Martin“…BACKGROUND: Genetic variants of inosine triphosphatase (ITPA) that confer reduced ITPase activity are associated with protection against ribavirin(RBV)-induced hemolytic anemia in peginterferon(IFN)/RBV-based treatment of hepatitis C virus (HCV). Patients with reduced ITPase activity showed improved treatment efficacy when treated with IFN/RBV. …”
Publicado 2018
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13490por Sookoian, Silvia, Flichman, Diego, Garaycoechea, Martin E., San Martino, Julio, Castaño, Gustavo O., Pirola, Carlos J.“…MALAT1 liver profiling was performed in three consecutive phases, including an exploratory stage (liver samples from patients with NAFLD who were morbidly obese [n = 47] and from 13 individuals with normal liver histology); a replication stage (patients with NAFLD and metabolic syndrome [n =49]); and a hypothesis‐driven stage (patients with chronic hepatitis C and autoimmune liver diseases, [n = 65]). …”
Publicado 2018
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13491“…BACKGROUND: Female gender and favorable IFNL3 genotypes are the primary independent predictors of spontaneous clearance of HCV infection. However, chronic hepatitis C infection occurs in numerous women carrying favorable IFNL3 genotypes, indicating that other host and/or virological factors contribute to the prognosis of infection. …”
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13492“…Recipients with chronic HD were generally older and male, had higher risks of developing post-transplant de novo ischaemic heart disease, tuberculosis and hepatitis C after adjustment. Pretransplant HD contributed to higher graft failure in the multivariate analysis (HR 1.38, p<0.05) after adjustment for the recipient age, sex, duration of dialysis and pretransplant diseases. …”
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13493por Siraj, Nejat, Achila, Oliver Okoth, Issac, John, Menghisteab, Efrem, Hailemariam, Maedn, Hagos, Semere, Gebremeskel, Yosan, Tesfamichael, Daniel“…BACKGROUND: Blood transfusion is associated with several risks particularly exposure to blood transfusion-transmissible infections (TTI), including: Hepatitis B virus (HBV), Hepatitis C virus (HCV), Human immunodeficiency virus (HIV) and Syphilis, among others. …”
Publicado 2018
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13494Prognostic factors in patients with HBV-related hepatocellular carcinoma following hepatic resectionpor Rungsakulkij, Narongsak, Suragul, Wikran, Mingphruedhi, Somkit, Tangtawee, Pongsatorn, Muangkaew, Paramin, Aeesoa, Suraida“…The association between recurrence and survival and various clinicopathological factors, including serum alpha-fetoprotein (AFP) level, platelet count, platelet-to-lymphocyte ratio, neutrophil-to-lymphocyte ratio, antiplatelet therapy, antiviral therapy, hepatitis C virus infection, and tumor-related characteristics, were assessed using univariate and multivariate logistic regression analysis. …”
Publicado 2018
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13495“…BACKGROUND: Many clinicians and insurance providers are reluctant to embrace recent guidelines identifying people who inject drugs (PWID) as a priority population to receive hepatitis C virus (HCV) treatment. The aim of this study was to evaluate the efficacy of direct-acting antiviral (DAA) HCV therapy in a real-world population comprised predominantly of PWID. …”
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13496por Piacentini, Sara, La Frazia, Simone, Riccio, Anna, Pedersen, Jens Z., Topai, Alessandra, Nicolotti, Orazio, Rossignol, Jean-Francois, Santoro, M. Gabriella“…Nitazoxanide is used in the clinic as a safe and effective antiprotozoal/antimicrobial drug; its antiviral activity was shown in patients infected with hepatitis-C virus, rotavirus and influenza viruses. …”
Publicado 2018
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13497“…BACKGROUND: With the introduction of direct acting antivirals, treatment of hepatitis C virus (HCV) in hard-to-reach populations is now feasible. …”
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13498por Ezzikouri, Sayeh, Elfihry, Raouia, Chihab, Hajar, Elmessaoudi-Idrissi, Mohcine, Zaidane, Imane, Jadid, Fatima Zahra, Karami, Adnane, Tahiri, Mohamed, Elhabazi, Abdellah, Kabine, Mostafa, Chair, Mohammed, Pineau, Pascal, Benjelloun, Soumaya“…We genotyped MBOAT7 rs641738 polymorphism in 971 consecutive Moroccan subjects, including 288 patients with chronic hepatitis C (CHC), 98 cases with spontaneous clearance of HCV, 268 patients with chronic hepatitis B (CHB), 126 spontaneously cleared HBV infections and 191 healthy controls. …”
Publicado 2018
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13499por Olea, Antonio, Grochowski, Janet, Luetkemeyer, Anne F, Robb, Valerie, Saberi, Parya“…BACKGROUND: The objective of the study was to evaluate the role of a clinical pharmacist in hepatitis C virus (HCV) treatment of patients living with HIV/HCV coinfection. …”
Publicado 2018
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13500por Nguyen, Lam Nhat, Zhao, Juan, Cao, Dechao, Dang, Xindi, Wang, Ling, Lian, Jianqi, Zhang, Ying, Jia, Zhansheng, Wu, Xiao Y., Morrison, Zheng, Xie, Qian, Ji, Yingjie, Zhang, Zheng, El Gazzar, Mohamed, Ning, Shunbin, Moorman, Jonathan P., Yao, Zhi Q.“…In this study, we investigated the machineries of T-cell homeostasis and telomeric DNA damage using a human model of hepatitis C virus (HCV) infection. We found that naïve CD4 T cells in chronically HCV-infected patients (HCV T cells) were significantly reduced due to apoptosis compared with age-matched healthy subjects (HSs). …”
Publicado 2018
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