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13621por Scaglione, Vincenzo, Mazzitelli, Maria, Costa, Chiara, Pisani, Vincenzo, Greco, Giuseppe, Serapide, Francesca, Lionello, Rosaria, La Gamba, Valentina, Marascio, Nadia, Trecarichi, Enrico Maria, Torti, Carlo“…Background and objectives: In Italy, Hepatitis C Virus (HCV) infections are most prevalent in people older than 50 years of age, who often experience multi-morbidities, take co-medications, and have a long history of liver disease. …”
Publicado 2020
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13622por Brown, Ashley, Welzel, Tania M., Conway, Brian, Negro, Francesco, Bräu, Norbert, Grebely, Jason, Puoti, Massimo, Aghemo, Alessio, Kleine, Henning, Pugatch, David, Mensa, Federico J., Chen, Yaozhu J., Lei, Yang, Lawitz, Eric, Asselah, Tarik“…BACKGROUND & AIMS: Adequate adherence to hepatitis C virus (HCV) treatment is believed to be a key component of treatment success because non‐adherence can potentially result in treatment failure and the emergence of resistant viral variants. …”
Publicado 2019
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13623“…The recognition of other blood-borne viruses, in particular hepatitis B and hepatitis C, further prompted the application of molecular tests to clinical medicine. …”
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13624por Piecha, Felix, Gänßler, Jan-Michael, Ozga, Ann-Kathrin, Wehmeyer, Malte H., Dietz, Julia, Kluwe, Johannes, Laschtowitz, Alena, von Felden, Johann, Sterneck, Martina, Jordan, Sabine, Pischke, Sven, Lohse, Ansgar W., Schulze zur Wiesch, Julian“…BACKGROUND: Re-treatment in patients with a chronic hepatitis C virus (HCV) infection and a previous failure to direct-acting antiviral (DAA) treatment remains a challenge. …”
Publicado 2020
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13625por Alvarez, Christian S., Ortiz, Jeremy, Bendfeldt‐Avila, Giovanna, Xie, Yi, Wang, Mingyi, Wu, Dongjing, Higson, Herbert, Lee, Elisa, Teshome, Kedest, Barnoya, Joaquin, Kleiner, David E., Groopman, John D., Orozco, Roberto, McGlynn, Katherine A., Gharzouzi, Eduardo, Dean, Michael“…The major risk factors in Guatemala are not well characterized, but the prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) appears to be low, while the prevalence of aflatoxin (AFB(1)) exposure appears to be high. …”
Publicado 2020
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13626por Gordon, Calvin J., Tchesnokov, Egor P., Woolner, Emma, Perry, Jason K., Feng, Joy Y., Porter, Danielle P., Götte, Matthias“…In this regard, the triphosphate forms of 2′-C-methylated compounds, including sofosbuvir, approved for the management of hepatitis C virus infection, and the broad-acting antivirals favipiravir and ribavirin, exhibited significant deficits. …”
Publicado 2020
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13627por McClarty, Leigh M, Cheuk, Eve, Ireland, Laurie, Kendall, Claire, Bibeau, Christine, Loeppky, Carla, Kasper, Ken, Keynan, Yoav, Blanchard, James, Becker, Marissa“…Nearly one-fifth (18%) of participants have an active hepatitis C virus infection and the cohort’s median CD4 count increased from 316 cells/mm(3) to 518 cells/mm(3) between time of entry into care and end of the first quarter in 2019. …”
Publicado 2020
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13628“…A structural similarity search showed that the Hepatitis C virus (HCV) NS3/4A protease has a striking three-dimensional structural similarity to the SARS-CoV2 M(pro) protease, particularly in the arrangement of key active site residues. …”
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13629por Tanioka, Nobuhisa, Maeda, Hiromichi, Tsuda, Sachi, Iwabu, Jun, Namikawa, Tsutomu, Iguchi, Mitsuko, Hanazaki, Kazuhiro“…He had a history of chronic hepatitis C and diabetes mellitus. Six months earlier, computed tomography (CT) revealed a 75-mm tumor arising from the jejunum, suspected to be a gastrointestinal stromal tumor (GIST) of the small intestine. …”
Publicado 2020
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13630por Li, Bin, Yan, Cong, Zhu, Jiamin, Chen, Xiaobing, Fu, Qihan, Zhang, Hangyu, Tong, Zhou, Liu, Lulu, Zheng, Yi, Zhao, Peng, Jiang, Weiqin, Fang, Weijia“…And compared to TME in hepatitis C virus (HCV) infected HCC, TME of HBV-related HCC is less vascularized and presents different immune components resulting in similar immunosuppression. …”
Publicado 2020
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13631por Anderson, Erik S., Russell, Carly, Basham, Kellie, Montgomery, Martha, Lozier, Helen, Crocker, Abigail, Zuluaga, Marisa, White, Douglas A. E.“…BACKGROUND: The opioid epidemic has led to an increase in the number of persons who inject drugs, and this population accounts for 12% of new human immunodeficiency virus (HIV) and 60% of new hepatitis C virus (HCV) infections in the United States annually. …”
Publicado 2020
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13632por Townsend, Luke, Blais, Pierre, Huh, Alex, Nayak, Leela, Elwing, Jill E, Sayuk, Gregory S“…Underlying liver diseases included hepatitis c viral infection (HCV) (17.5%), alcohol (28.6%), alcohol and HCV (30.1%), and cryptogenic/metabolic (15.9%). …”
Publicado 2019
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13633por Romero, Maite Padrón, Acevedo Ribó, Mercedes M., Hormigos, Francisco Javier Ahijado, Crespo, Francisco Díaz, Bravo, Laura Cueto, Corredor, Cristina Herraiz, Rojo, María Ángeles Fernández, Izquierdo, Rafael Díaz-Tejeiro“…However, the presence of mixed cryoglobulinemia in this patient who was hepatitis C serological marker negative and who had poor renal function recovery after immunosuppressive treatment made us suspect other pathologies. …”
Publicado 2020
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13634por Choi, Hye Yeon, Siddique, Hifzur R., Zheng, Mengmei, Kou, Yi, Yeh, Da-Wei, Machida, Tatsuya, Chen, Chia-Lin, Uthaya Kumar, Dinesh Babu, Punj, Vasu, Winer, Peleg, Pita, Alejandro, Sher, Linda, Tahara, Stanley M., Ray, Ratna B., Liang, Chengyu, Chen, Lin, Tsukamoto, Hidekazu, Machida, Keigo“…We examined hepatocellular carcinoma (HCC) development in alcohol Western diet-fed hepatitis C virus NS5A Tg mice with hepatocyte-specific TBC1D15 deficiency or expression of non-phosphorylatable NUMB mutations. …”
Publicado 2020
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13635“…This study investigated the frequency of SENV (genotypes D and H) infections in Iraqi patients with thalassemic patients infected and not infected with hepatitis C virus. The study involved 150 β-thalassemia patients (75 with HCV infections and 75 without) and 75 healthy blood donors. …”
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13636por Ono, Chikako, Fukuhara, Takasuke, Li, Songling, Wang, Jian, Sato, Asuka, Izumi, Takuma, Fauzyah, Yuzy, Yamamoto, Takuya, Morioka, Yuhei, Dokholyan, Nikolay V., Standley, Daron M., Matsuura, Yoshiharu“…One of the determinants for tissue tropism of hepatitis C virus (HCV) is miR-122, a liver-specific microRNA. …”
Publicado 2020
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13637por Alvarez, Christian S, Hernández, Elisa, Escobar, Kira, Villagrán, Carmen I, Kroker-Lobos, María F, Rivera-Andrade, Alvaro, Smith, Joshua W, Egner, Patricia A, Lazo, Mariana, Freedman, Neal D, Guallar, Eliseo, Dean, Michael, Graubard, Barry I, Groopman, John D, Ramírez-Zea, Manuel, McGlynn, Katherine A“…The reasons for this heavy burden of disease are not clear as the prevalence of prominent risk factors, such as hepatitis B virus, hepatitis C virus and heavy alcohol consumption, appears to be low. …”
Publicado 2020
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13638por Flamm, Steven, Mutimer, David, Asatryan, Armen, Wang, Stanley, Rockstroh, Jürgen, Horsmans, Yves, Kwo, Paul Y., Weiland, Ola, Villa, Erica, Heo, Jeong, Gane, Edward, Ryder, Stephen D., Welzel, Tania M., Ruane, Peter J., Agarwal, Kosh, Ng, Teresa I., Xue, Zhenyi, Lovell, Sandra S., Krishnan, Preethi, Kopecky‐Bromberg, Sarah, Trinh, Roger, Mensa, Federico J., Wyles, David L.“…Glecaprevir coformulated with pibrentasvir (G/P) is approved to treat hepatitis C virus (HCV) infection and was highly efficacious in phase 2 and 3 studies. …”
Publicado 2018
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13639por Langlois, Anne-Claire, Manzoni, Giulia, Vincensini, Laetitia, Coppée, Romain, Marinach, Carine, Guérin, Maryse, Huby, Thierry, Carrière, Véronique, Cosset, François-Loïc, Dreux, Marlène, Rubinstein, Eric, Silvie, Olivier“…Two receptors of the Hepatitis C virus (HCV), the tetraspanin CD81 and the scavenger receptor class B type 1 (SR-B1), play an important role during the entry of Plasmodium sporozoites into hepatocytes. …”
Publicado 2020
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13640“…The relationship of drug use, especially IV drugs, has been determined to be associated with an increased possibility of reactive serology (Centers for Disease Control and Prevention (USCDC) in Division of Viral Hepatitis, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention. Hepatitis C questions and answers for health professionals. https://www.cdc.gov/hepatitis/hcv/hcvfaq.htm; Centers for Disease Control and Prevention (USCDC) in infectious diseases, opioids and injection drug use, 2018. https://www.cdc.gov/pwid/opioid-use.html; HIH National Institute on Drug Abuse in Health Consequences of Drug Misuse, 2017. https://www.drugabuse.gov/related-topics/health-consequences-drug-misuse). …”
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