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1441por Afdhal, N H, Zeuzem, S, Schooley, R T, Thomas, D L, Ward, J W, Litwin, A H, Razavi, H, Castera, L, Poynard, T, Muir, A, Mehta, S H, Dee, L, Graham, C, Church, D R, Talal, A H, Sulkowski, M S, Jacobson, I M for the New Paradigm of HCV Therapy Meeting Participants“…Emerging data indicate that all-oral antiviral treatments for chronic hepatitis C virus (HCV) will become a reality in the near future. …”
Publicado 2013
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1442“…The hepatitis C virus nonstructural NS5A protein has roles in genome replication, virus assembly, and modulation of host pathways. …”
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1443por Brakha, Carine, Arvers, Philippe, Villiers, Florent, Marlu, Alice, Buhot, Arnaud, Livache, Thierry, Calemczuk, Roberto, Zarski, Jean-Pierre, Villiers, Christian L, Marche, Patrice N, Villiers, Marie-Bernadette“…ABSTRACT: Hepatitis C virus infection leads to liver disease whose severity can range from mild to serious lifelong illness. …”
Publicado 2014
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1444por Kohler, James J, Nettles, James H, Amblard, Franck, Hurwitz, Selwyn J, Bassit, Leda, Stanton, Richard A, Ehteshami, Maryam, Schinazi, Raymond F“…Recent progress in the understanding of hepatitis C virus (HCV) biology and the availability of in vitro models to study its replication have facilitated the development of direct-acting antiviral agents (DAAs) that target specific steps in the viral replication cycle. …”
Publicado 2014
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1445
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1446“…In recent years, clinical research in the field of new treatments for chronic hepatitis C (HCV) has been devoted to developing regimens based on direct-acting antivirals (DAAs), with the goal of increasing treatment efficacy and improving tolerability and safety. …”
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1447por LaFleur, Joanne, Hoop, Robert, Morgan, Timothy, DuVall, Scott L, Pandya, Prashant, Korner, Eli, Knippenberg, Kristin, Hayden, Candace, Nelson, Richard E“…BACKGROUND: Patients with chronic hepatitis C (HCV) frequently discontinued dual therapy with pegylated interferon alfa (Peg-IFN) plus ribavirin (RBV) before reaching the recommended duration of 48 or 24 weeks for genotypes (G) 1/4 or 2/3, respectively. …”
Publicado 2014
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1448“…BACKGROUND: Adherence is a crucial point for the successful treatment of a hepatitis-C virus infection. Studies have shown that especially adherence to ribavirin is important. …”
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1449por Trien, Remi, Cooper, Chad J., Paez, David, Colon, Edgardo, Ajmal, Shajeea, Salameh, Hasan“…She had been treated for hepatitis C with telaprevir, ribavirin, and interferon-alpha-2b for 6 months. …”
Publicado 2014
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1450por Boelen, Lies, Teutsch, Suzy, Wilson, David P., Dolan, Kate, Dore, Greg J., Lloyd, Andrew R., Luciani, Fabio“…BACKGROUND: Shared injecting apparatus during drug use is the premier risk factor for hepatitis C virus (HCV) transmission. AIMS: To estimate the per-event probability of HCV infection during a sharing event, and the transmission probability of HCV from contaminated injecting apparatus. …”
Publicado 2014
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1451por Saidi, R. F., Hertl, M., Chung, R. T., Ko, D. S. C., Kawai, T., Markmann, J., Bhan, A. K., Cosimi, A. B., Elias, N.“…Background: Hepatitis C (HCV) is the most common indication for liver transplantation in the US. …”
Publicado 2011
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1452por Saleha, Shamim, Kamal, Anwar, Ullah, Farman, Khan, Nasar, Mahmood, Asif, Khan, Sanaullah“…Determination of an individual's hepatitis C virus (HCV) genotypes prior to antiviral therapy has become increasingly important for the clinical management and prognosis of HCV infection. …”
Publicado 2014
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1454por Kwon, Geun-Yong, Lee, Hyungmin, Gwack, Jin, Lee, Sang-Won, Ki, Moran, Youn, Seung-Ki“…BACKGROUND/AIMS: In Korea, hepatitis C is included as an infectious disease in a sentinel surveillance system. …”
Publicado 2014
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1455por Lara, James, López-Labrador, F Xavier, González-Candelas, Fernando, Berenguer, Marina, Khudyakov, Yury E“…BACKGROUND: Chronic infection with hepatitis C virus (HCV) is a risk factor for liver diseases such as fibrosis, cirrhosis and hepatocellular carcinoma. …”
Publicado 2014
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1456por Pfeffer, Lawrence M., Li, Kui, Fleckenstein, Jaquelyn F., Marion, Tony N., Diament, Joel, Yang, Chuan He, Pfeffer, Susan R., Fan, Meiyun, Handorf, Elizabeth, Handorf, Charles R.“…Infection with the hepatitis C virus (HCV) is a major cause of chronic liver diseases and hepatocellular carcinoma worldwide, and thus represents a significant public health problem. …”
Publicado 2014
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1457“…BACKGROUND AND AIMS: Increasing evidence demonstrates that hepatitis C virus (HCV) infection is associated with atherosclerosis. …”
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1458por Mousa, Omar Y. S., Khalaf, Rossa, Shannon, Rhonda L., Egwim, Chukwuma I., Zela, Scott A., Ankoma-Sey, Victor“…Recent clinical trials reported an association between DRESS and telaprevir (TVR), an NS3/4A protease inhibitor of chronic hepatitis C (CHC) virus genotype 1. Its diagnosis is challenging given the variable pattern of cutaneous eruption and the myriad internal organ involvement. …”
Publicado 2014
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1459por Baron, Pedro W., Amankonah, Thomas, Cubas, Robert F., Kore, Arputharaj H., Elihu, Arvand, de Vera, Michael E., Perez, Mia C. N.“…She has a history of cirrhosis secondary to chronic hepatitis C (HCV) and was treated with interferon and ribavirin with sustained virological response. …”
Publicado 2014
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1460por Esmaeilzadeh, Abdolreza, Erfanmanesh, Maryam, Ghasemi, Sousan, Mohammadi, Farzaneh“…BACKGROUND: Hepatitis C Virus (HCV), a public health problem, is an enveloped, single-stranded RNA virus and a member of the Hepacivirus genus of the Flaviviridae family. …”
Publicado 2014
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