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  1. 2061
    “…IMPORTANCE: It is estimated that up to 50% of patients with ERBB2 (HER2)-positive metastatic breast cancer (MBC) will develop brain metastases (BMs), which is associated with poor prognosis. …”
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    Tucatinib vs Placebo, Both in Combination With Trastuzumab and Capecitabine, for Previously Treated ERBB2 (HER2)-Positive Metastatic Breast Cancer in Patients With Brain Metastases: Updated Exploratory Analysis of the HER2CLIMB Randomized Clinical Trial
  2. 2062
    por Ordan, Julien Marius
    Publicado 2017
    “…Visit of Her Excellency Dr Ameenah Gurib-Fakim President of the Republic of Mauritius,16/06/2017…”
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    Visit of Her Excellency Dr Ameenah Gurib-Fakim President of the Republic of Mauritius,16/06/2017
  3. 2063
    por Ordan, Julien
    Publicado 2019
    “…Visit by Her Excellency Ms Elba Rosa Pérez Montoya Minister of Science, Technology and Environment Republic of Cuba…”
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    Her Excellency Ms Elba Rosa Pérez Montoya Minister of Science, Technology and Environment Republic of Cuba
  4. 2064
    por Nijhoff, Frank, Shi, Yang, Zhang, Da-jun
    Publicado 2020
    “…This proceedings volume gathers together selected works from the 2018 “Asymptotic, Algebraic and Geometric Aspects of Integrable Systems” workshop that was held at TSIMF Yau Mathematical Sciences Center in Hainan China, honoring Nalini Joshi on her 60th birthday. The papers cover recent advances in asymptotic, algebraic and geometric methods in the study of discrete integrable systems. …”
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    Asymptotic, Algebraic and Geometric Aspects of Integrable Systems : in Honor of Nalini Joshi on her 60th Birthday
  5. 2065
    por Huson, Barbara
    Publicado 2021
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    Rewire for Wealth: Three Steps Any Woman Can Take to Program Her Brain for Financial Success
  6. 2066
    por Adamatzky, Andrew, Kendon, Vivien
    Publicado 2019
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    From astrophysics to unconventional computation: essays presented to Susan Stepney on the occasion of her 60th birthday
  7. 2067
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    The art of modelling computational systems: essays dedicated to catuscia palamidessi on the occasion of her 60th birthday
  8. 2068
    “…KRAS, NRAS and BRAF mutations, HER2 amplification and overexpression, and microsatellite instability (MSI) were tested in 8355 CRC samples. …”
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    Online Artículo Texto
    KRAS, NRAS, BRAF, HER2 and MSI Status in a Large Consecutive Series of Colorectal Carcinomas
  9. 2069
    “…BACKGROUND: Human epidermal growth factor receptor 2 (HER2) low breast cancer (BC) accounts for 30–51% of all BCs. …”
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    Online Artículo Texto
    Development and validation of a prognostic model for HER2-low breast cancer to evaluate neoadjuvant therapy
  10. 2070
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    Matters Arising: PREDICT underestimates survival of patients with HER2-positive early-stage breast cancer
  11. 2071
    “…Neoadjuvant therapy (NAT) is currently recommended to patients with human epidermal growth factor receptor 2-positive breast cancer (HER2+ BC) that typically exhibit a poor prognosis. …”
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    A generalized non-linear model predicting efficacy of neoadjuvant therapy in HER2+ breast cancer
  12. 2072
    “…Our results support further evaluation of the QDB method as an alternative to IHC to meet the emerging need of identifying tumors with low Her2 expression (Her2-low) in daily clinical practice.…”
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    Online Artículo Texto
    ELISA-like QDB method to meet the emerging need of Her2 assessment for breast cancer patients
  13. 2073
    “…Endocrine therapy is the backbone treatment for hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative breast cancer, the most common subtype. …”
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    Online Artículo Texto
    Evaluating Elacestrant in the Management of ER-Positive, HER2-Negative Advanced Breast Cancer: Evidence to Date
  14. 2074
    “…In this work, we focus on the automatic identification of gastroesophageal adenocarcinoma (GEA) patients that qualify for a personalised therapy targeting epidermal growth factor receptor 2 (HER2). We present a deep-learning method for scoring microscopy images of GEA for the presence of HER2 overexpression. …”
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    Predicting the HER2 status in oesophageal cancer from tissue microarrays using convolutional neural networks
  15. 2075
    “…Biological studies were performed on the SKOV-3 cell line (HER2+) and showed high specificity of binding to the receptors and internalization capabilities, whereas MDA-MB-231 cells (HER2−) did not. …”
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    Online Artículo Texto
    Doxorubicin- and Trastuzumab-Modified Gold Nanoparticles as Potential Multimodal Agents for Targeted Therapy of HER2+ Cancers
  16. 2076
    “…PURPOSE: In hormone receptor–positive (HR+)/HER2− metastatic breast cancer (MBC), it is imperative to identify patients who respond poorly to cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) and to discover therapeutic targets to reverse this resistance. …”
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    Online Artículo Texto
    CCNE1 and PLK1 Mediate Resistance to Palbociclib in HR+/HER2− Metastatic Breast Cancer
  17. 2077
    “…The designed biosensor makes use of the specific binding of HER-2 protein to HER-2 Ab and disruption of the orientation of LCs. …”
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    Online Artículo Texto
    Liquid crystal-assisted optical biosensor for early-stage diagnosis of mammary glands using HER-2
  18. 2078
    “…Amplification of HER2 can drive the proliferation of cancer cells, and several inhibitors of HER2 have been successfully developed. …”
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    Computational and Functional Analyses of HER2 Mutations Reveal Allosteric Activation Mechanisms and Altered Pharmacologic Effects
  19. 2079
    “…PURPOSE: The detection of human epidermal growth factor receptor 2 (HER2) expression status is essential to determining the chemotherapy regimen for breast cancer patients and to improving their prognosis. …”
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    Online Artículo Texto
    Deep learning radiomics model based on breast ultrasound video to predict HER2 expression status
  20. 2080
    “…The type of fixative used for preserving tumor specimens can significantly impact the performance of the immunohistochemistry and in situ hybridization assays used for assessing human epidermal growth factor receptor 2 (HER2) status. This study reports the prevalence of the use of alternative fixatives other than the guideline-recommended 10% neutral buffered formalin (NBF) during HER2 testing in a real-world setting. …”
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    Online Artículo Texto
    Assessment of the Impact of Alternative Fixatives on HER2 Detection in Breast Cancer and Gastric Cancer Tumor Specimens
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