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2881“…HER2+ breast cancer is currently managed with multidisciplinary treatment strategies including surgery, radiation, chemotherapy, and targeted therapy. …”
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2882por Princip, Mary, Langraf-Meister, Rebecca E, Slavich, George M, Pazhenkottil, Aju P, Hackl-Zuccarella, Claudia, Cammann, Victoria L, Ghadri, Jelena R, Templin, Christian, von Känel, RolandEnlace del recurso
Publicado 2022
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2883por Barrios, D. M., Phillips, G. S., Geisler, A. N., Trelles, S. R., Markova, A., Noor, S. J., Quigley, E. A., Haliasos, H. C., Moy, A. P., Schram, A. M., Bromberg, J., Funt, S. A., Voss, M. H., Drilon, A., Hellmann, M. D., Comen, E. A., Narala, S., Patel, A. B., Wetzel, M., Jung, J. Y., Leung, D. Y. M., Lacouture, M. E.“…In oncology, pruritus-associated cutaneous adverse events (paCAEs) are frequent with immune checkpoint inhibitors (CPIs) and targeted anti-human epidermal growth factor receptor 2 (HER2) therapies. Thus, we sought to evaluate the efficacy and safety of IgE blockade with omalizumab in cancer patients with refractory paCAEs related to CPIs and anti-HER2 agents. …”
Publicado 2021
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2885por Torrisi, Rosalba, Vaira, Valentina, Giordano, Laura, Destro, Annarita, Basilico, Vera, Mazzara, Saveria, Salvini, Piermario, Gaudioso, Gabriella, Fernandes, Bethania, Rudini, Noemi, Masci, Giovanna, Santoro, Armando“…We retrospectively investigated in women treated with fulvestrant for HR+/HER2 negative advanced breast cancer clinical, pathological and molecular features associated with long-term benefit from treatment defined as being progression-free at 18 months. …”
Publicado 2022
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2886por Costa-Reis, Patricia, Maurer, Kelly, Petri, Michelle A, Levy Erez, Daniella, Zhao, Xue, Faig, Walter, Burnham, Jon, O'Neil, Kathleen, Klein-Gitelman, Marisa S, von Scheven, Emily, Schanberg, Laura Eve, Sullivan, Kathleen E“…Urine was analysed for human epidermal growth factor receptor 2 (HER2), tumour necrosis factor-like weak inducer of apoptosis and vascular cell adhesion molecule-1 (VCAM-1) by ELISA. …”
Publicado 2022
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2887por Blum, Joanne L., Laird, A. Douglas, Litton, Jennifer K., Rugo, Hope S., Ettl, Johannes, Hurvitz, Sara A., Martin, Miguel, Roché, Henri H., Lee, Kyung-Hun, Goodwin, Annabel, Chen, Ying, Lanzalone, Silvana, Chelliserry, Jijumon, Czibere, Akos, Hopkins, Julia F., Albacker, Lee A., Mina, Lida A.Enlace del recurso
Publicado 2022
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2888por Attia, Samar, Abd El Hafez, Amal, Abdel-Aziz, Azza, Elmetwaly, Shimaa, Mokhtar, Nagwa“…OBJECTIVE: Programmed death-ligand 1 (PD-L1) and human epidermal growth factor receptor 2 (HER2) are currently considered as prognostic markers and therapeutic targets in many human cancers. …”
Publicado 2022
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2889“…The results show that IHC can be used as the primary screening for HER2 gene status detection; IHC (2+) and IHC (3+) have false positives, which are related to chromosome 17 polysomy, so FISH should be done to confirm the diagnosis.…”
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2890HEROHE Challenge: Predicting HER2 Status in Breast Cancer from Hematoxylin–Eosin Whole-Slide Imagingpor Conde-Sousa, Eduardo, Vale, João, Feng, Ming, Xu, Kele, Wang, Yin, Della Mea, Vincenzo, La Barbera, David, Montahaei, Ehsan, Baghshah, Mahdieh, Turzynski, Andreas, Gildenblat, Jacob, Klaiman, Eldad, Hong, Yiyu, Aresta, Guilherme, Araújo, Teresa, Aguiar, Paulo, Eloy, Catarina, Polónia, Antonio“…In this work, we present the HER2 on hematoxylin and eosin (HEROHE) challenge, a parallel event of the 16th European Congress on Digital Pathology, which aimed to predict the HER2 status in breast cancer based only on hematoxylin–eosin-stained tissue samples, thus avoiding specialized techniques. …”
Publicado 2022
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2891por Wei, Yali, An, Xu, Cao, Qinmei, Che, Nanying, Xue, Yuanyuan, Deng, Haiteng, Wang, Qingtao, Zhou, Rui“…Patients with HER2-low BC can benefit from new HER2 targeted therapy. …”
Publicado 2022
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2892por Wang, Mingdian, Wang, Xiang, Li, Yiwei, Li, Qingguo, Cai, Sanjun, Li, Xinxiang, Ma, Maoguang“…PURPOSE: HER2-positive colorectal cancer was drawn increasing attention in recent years. …”
Publicado 2022
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2893“…OBJECTIVE: To observe the effect of trastuzumab and cisplatin combined with irinotecan in the treatment of advanced Her-2 positive gastric cancer and its influence on disease control rate. …”
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2894por Ciérvide, Raquel, Montero, Ángel, García-Rico, Eduardo, García-Aranda, Mariola, Herrero, Mercedes, Skaarup, Jessica, Benassi, Leticia, Barrera, Maria José, Vega, Estela, Rojas, Beatriz, Bratos, Raquel, Luna, Ana, Parras, Manuela, López, María, Delgado, Ana, Quevedo, Paloma, Castilla, Silvia, Feyjoo, Margarita, Higueras, Ana, Prieto, Mario, Suarez-Gauthier, Ana, Garcia-Cañamaque, Lina, Escolán, Nieves, Álvarez, Beatriz, Chen, Xin, Alonso, Rosa, López, Mercedes, Hernando, Ovidio, Valero, Jeannette, Sánchez, Emilio, Ciruelos, Eva, Rubio, Carmen“…Patients with localized TN/HER2+ tumors were enrolled in this prospective study. …”
Publicado 2022
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2895por Spring, Laura M., Han, Hyo, Liu, Minetta C., Hamilton, Erika, Irie, Hanna, Santa-Maria, Cesar A., Reeves, James, Pan, Peng, Shan, Ming, Tang, Yongqiang, Graham, Julie R., Hazard, Sebastien, Ellisen, Leif W., Isakoff, Steven J.Enlace del recurso
Publicado 2022
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2896por Fabi, Alessandra, Buono, Giuseppe, Bria, Emilio, Bianchini, Giampaolo, Curigliano, Giuseppe, De Laurentiis, Michelino, De Placido, Sabino, Del Mastro, Lucia, Guarneri, Valentina, Generali, Daniele, Livi, Lorenzo, Lorusso, Vito, Montemurro, Filippo, Puglisi, Fabio, Vigneri, Paolo, Zambelli, Alberto, Arpino, Grazia“…The treatment of HR+/HER2- metastatic breast cancer with cyclin-dependent kinases 4 and 6 inhibitors combined with endocrine therapy has recently emerged as the most relevant therapeutic strategy. …”
Publicado 2022
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2897por Wang, Xiaolei, Huang, Yuxia, Yang, Zhen, Yang, Yang, Wei, Fenfen, Yan, Min, Li, Fanfan“…A study to examine the efficacy and risk factors associated with pyrrotinib in the second- and third-line treatment of advanced breast cancer with Human epidermal growth factor receptor 2- (HER2-) positive cells was conducted. Progression-free survival (PFS) was assessed as the primary endpoint, and the objective response rate (ORR), overall survival (OS), and safety were secondary endpoints. …”
Publicado 2022
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2898por Di Cosimo, Serena, La Rocca, Eliana, Ljevar, Silva, De Santis, Maria Carmen, Bini, Marta, Cappelletti, Vera, Valenti, Marta, Baili, Paolo, de Braud, Filippo G., Folli, Secondo, Scaperrotta, Gianfranco, Volpi, Chiara, Vingiani, Andrea, Vernieri, Claudio, Verderio, Paolo, Miceli, Rosalba, Pruneri, Giancarlo“…Background: Previous data, mostly from clinical trials, reported that HER2-low status is associated with low pathological complete response (pCR), and favourable prognosis. …”
Publicado 2022
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2899por López Rodrigo, M.V., Osca Oliver, A., Palomo Monge, M., Tascón Guerra, M.F., Pérez Fominaya, M.“…She goes to the emergency department brought by her father and brother presenting psychomotor agitation, verbiage, flight of ideas, loss of the common thread in the speech, referring delusional ideas with experience of harm. …”
Publicado 2022
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2900por Singh, Divya, Agarwal, Akansha, Anthony, Michael L, Paul, Pranoy, Singh, Monika, Rao, Shalinee, Ravi, Bina, Chowdhury, Nilotpal“…Results: Tubule formation and/or Indian file pattern were significantly associated with ER in all tumors (P-value <0.001), as well as separately for grade II, grade III, HER2-negative and HER2-positive tumors. Comparable results were obtained for their association with PR. …”
Publicado 2022
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