Mostrando 3,441 - 3,460 Resultados de 58,773 Para Buscar '"Her"', tiempo de consulta: 0.47s Limitar resultados
  1. 3441
    “…Breast cancers are hormonally regulated and are categorized ER+/PR+/HER2-, ER-/PR-/HER2+, ER+/PR-/HER2-, and ER-/PR-/HER2-. …”
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  2. 3442
  3. 3443
    “…This study focuses on its relationship with the Oncotype Dx (ODX) test risk score (RS) in patients with hormone-receptor-positive, HER2-negative (HR+HER2−) breast cancer. Methods: We retrospectively analyzed 401 HR+HER2− breast cancer patients from Gangnam Severance Hospital who underwent ODX tests (May 2014–April 2020). …”
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  4. 3444
  5. 3445
  6. 3446
    “…METHODS: The study included 3055 female patients with stage II or III HER2-negative breast cancer. The primary outcomes were time to recurrence or death (TTR) and overall survival (OS). …”
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  7. 3447
    “…The PATRICIA study (NCT02536339) examined the efficacy and safety of pertuzumab plus high-dose trastuzumab in patients with HER2-positive metastatic breast cancer (MBC) with progressive central nervous system (CNS) metastases following radiotherapy. …”
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  8. 3448
    “…The antibody-drug conjugate, trastuzumab-deruxtecan (T-DXd), which combines the anti-HER2 antibody trastuzumab with a topoisomerase type 1 inhibitor, showed high efficacy not only against HER2-positive but also HER2-low metastatic BCs, expressing HER2 at a lower level. …”
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  9. 3449
    “…BACKGROUND: Metastatic breast cancer (MBC) patients with low expression of human epidermal growth factor 2 (HER2) have been proven to benefit from HER2 targeted therapy. …”
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  10. 3450
  11. 3451
  12. 3452
    “…METHODS: Ten patients with advanced breast cancer whose tumors overexpressed HER-2, but not ER or PgR, were treated with weekly trastuzumab at standard doses with or without chemotherapy. …”
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  13. 3453
  14. 3454
    “…Pertuzumab represents the first in a new class of targeted therapeutics known as HER dimerisation inhibitors. We conducted a phase Ib study to determine the maximum-tolerated dose, the dose limiting toxicities (DLT), and pharmacokinetic (PK) interaction of docetaxel when administered in combination with pertuzumab. …”
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  15. 3455
  16. 3456
    “…There was no relationship between HER-2 and other biological markers. No single pretreatment or postchemotherapy biological parameter predicted response by any modality of assessment. …”
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  17. 3457
    “…Here, we report the generation and characterization of CD4+ T cell clones specifically recognizing a HER-2/neu-derived peptide (776–788) [designated HER2(776–788)]. …”
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  18. 3458
  19. 3459
  20. 3460
    “…BACKGROUND: Accurate assessment of HER-2/neu status is crucial for proper prognostic information and to offer direct appropriate treatment for breast cancer patients. …”
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