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3761por Song, Zhengbo, Li, Yuping, Chen, Shiqing, Ying, Shenpeng, Xu, Shuguang, Huang, Jianjin, Wu, Dan, Lv, Dongqing, Bei, Ting, Liu, Shuxun, Huang, Xiaoping, Xie, Congying, Wu, Xiaoyu, Fu, Jianfei, Hua, Feng, Wang, Wenxian, Xu, Chunwei, Gao, Chan, Cai, Shangli, Lu, Shun, Zhang, Yiping“…BACKGROUND: There is currently a lack of effective treatments for non-small cell lung cancer (NSCLC) patients harboring HER2 mutations. We examined the efficacy and safety of, and potential resistance mechanism to, pyrotinib, a pan-HER inhibitor, in advanced NSCLC carrying HER2 mutations. …”
Publicado 2022
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3762por Zuzarte, Monica, Francisco, Vera, Neves, Bruno, Liberal, Joana, Cavaleiro, Carlos, Canhoto, Jorge, Salgueiro, Lígia, Cruz, Maria Teresa“…Lavandula viridis L´Hér. is an endemic Iberian species with a high essential oil yield and a pleasant lemon scent. …”
Publicado 2022
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3763por Xie, Suhong, Wang, Yan, Gong, Zhiyun, Li, Yuan, Yang, Wentao, Liu, Guangyu, Li, Jianwei, Hu, Xin, Wang, Yanchun, Tong, Yin, Yuan, Peng, Si, Yiran, Kang, Yikun, Mao, Yong, Qi, Xiaowei, Liu, Yankui, Ou, Jiajia, Li, Zhaoliang, Pan, Xin, Lv, Zhaoqing, Kaji, Kavanaugh, Guo, Lin, Lu, Renquan“…Two hundred twenty-four breast cancer patients with paired tissue and plasma samples were enrolled from 3 clinical centers to evaluate sensitivity and specificity of a digital PCR HER2 amplification assay. All patients were histologically confirmed diagnosis of locally advanced and recurrent or metastatic breast cancer with stage III/IV and had tissue HER2 status determinations using IHC/FISH. …”
Publicado 2022
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3764“…Human epidermal growth factor receptor 2 (HER2)‐positive is a particularly aggressive type of the breast cancer. …”
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3765por Parry, Monica, Bjørnnes, Ann Kristin, Harrington, Margaret, Duong, Michelle, El Ali, Salma, O’Hara, Arland, Clarke, Hance, Cooper, Lynn, Hart, Donna, Harvey, Paula, Lalloo, Chitra, McFetridge-Durdle, Judith, McGillion, Michael H., Norris, Colleen, Pilote, Louise, Price, Jennifer, Stinson, Jennifer, Watt-Watson, JudyEnlace del recurso
Publicado 2021
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3766por Shishido, Stephanie N., Masson, Rahul, Xu, Liya, Welter, Lisa, Prabakar, Rishvanth Kaliappan, D’ Souza, Anishka, Spicer, Darcy, Kang, Irene, Jayachandran, Priya, Hicks, James, Lu, Janice, Kuhn, Peter“…In rare instances (2–4% of cases) patients with mBC have ERBB2 (HER2) activating mutations but are ERBB2 non-amplified. …”
Publicado 2022
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3768por Ayéna, Aimé Cézaire T., Dosseh, Kossivi, Idoh, Kokou, Agbonon, Amegnona, Gbeassor, MessanviEnlace del recurso
Publicado 2022
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3769“…PURPOSE: This study was determined to evaluate the prognostic value of neutrophil-to-lymphocyte ratio (NLR) and C-reactive protein/albumin ratio (CAR) prior to surgery in luminal breast cancers (BC) with HER2-negativity. METHODS: The clinical data of 708 HER2-negative luminal BC patients from January 2013 to December 2016 were retrospectively collected and analyzed. …”
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3770por Oscorbin, Igor P., Smertina, Maria A., Pronyaeva, Ksenia A., Voskoboev, Mikhail E., Boyarskikh, Ulyana A., Kechin, Andrey A., Demidova, Irina A., Filipenko, Maxim L.“…Existing methods for detecting HER2 and MET amplifications are time and labor-consuming, and alternative methods are needed. …”
Publicado 2022
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3771por Cogliati, Viola, Capici, Serena, Pepe, Francesca Fulvia, di Mauro, Pierluigi, Riva, Francesca, Cicchiello, Federica, Maggioni, Claudia, Cordani, Nicoletta, Cerrito, Maria Grazia, Cazzaniga, Marina ElenaEnlace del recurso
Publicado 2022
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3772por He, Miao, Hu, Yu, Wang, Dongdong, Sun, Meili, Li, Huijie, Yan, Peng, Meng, Yingxu, Zhang, Ran, Li, Li, Yu, Dexin, Wang, Xiuwen“…OBJECTIVE: This study aims to assess the performance of machine learning (ML)-based contrast-enhanced CT radiomics analysis for predicating the efficacy of anti-HER2 therapy for patients with liver metastases from breast cancer. …”
Publicado 2022
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3773por Olmedo, Maria Eugenia, Cervera, Raquel, Cabezon-Gutierrez, Luis, Lage, Yolanda, Corral de la Fuente, Elena, Gómez Rueda, Ana, Mielgo-Rubio, Xabier, Trujillo, Juan Carlos, Couñago, Felipe“…Recent genome studies of lung adenocarcinoma have identified other possible therapeutic targets, including RET, NTRK fusions, c-MET alterations, and activating mutations in KRAS, BRAF, and HER2, all with frequencies greater than 1%. Lung cancers harbouring these genome changes can potentially be treated with agents approved for other indications or under clinical development. …”
Publicado 2022
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3774por Zhang, Qing, Han, Wenjie, Xu, Zhixiao, Li, Yinling, Chen, Lu, Bai, Zhengyu, Yang, Lin, Wang, Xiaolei“…In particular, the research on catalysts towards the oxygen evolution reaction (OER), oxygen reduction reaction (ORR), and hydrogen evolution reaction (HER) has become more urgent, and the development of multifunctional electrocatalysts has become a research trend. …”
Publicado 2020
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3775por Nivetha, Ravi, Kollu, Pratap, Chandar, Krishna, Pitchaimuthu, Sudhagar, Jeong, Soon Kwan, Grace, Andrews Nirmala“…The material can be used as an efficient electrocatalyst and photocatalyst for a hydrogen evolution reaction (HER) in an alkaline medium and the same was further tested for the degradation of organic pollutants. …”
Publicado 2019
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3776por Fan, Yu, Li, Qinhan, Shen, Qi, Liu, Zhifu, Zhang, Zhenan, Hu, Shuai, Yu, Wei, He, Zhisong, He, Qun, Zhang, Qian“…METHODS: We detected the expression of NECTIN-4, TROP-2, and HER2, which are the corresponding targets of ADCs EV, SG, and RC-48 in muscle-invasive UC through immunohistochemistry. …”
Publicado 2022
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3777por Waks, Adrienne G., Desai, Neelam V., Li, Tianyu, Poorvu, Philip D., Partridge, Ann H., Sinclair, Natalie, Spring, Laura M., Faggen, Meredith, Constantine, Michael, Metzger, Otto, Alberti, Jillian, Deane, Julia, Rosenberg, Shoshana M., Frank, Elizabeth, Tolaney, Sara M., Krop, Ian E., Tung, Nadine M., Tayob, Nabihah, King, Tari A., Mittendorf, Elizabeth A., Winer, Eric P.“…De-escalating adjuvant therapy following pathologic complete response (pCR) to an abbreviated neoadjuvant regimen in human epidermal growth factor receptor 2-positive (HER2+) breast cancer is the focus of international research efforts. …”
Publicado 2022
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3778por Zhao, Songbo, Bi, Yangang, Wang, Zhenfang, Zhang, Fantao, Zhang, Yang, Xu, Yongyun“…BACKGROUND: To evaluate the diagnostic accuracy of single gastroscopy, multi-slice spiral CT, HER-2 or tumor markers, and their combination in the diagnosis of gastric cancer. …”
Publicado 2022
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3779por An, Selena J., Duchesneau, Emilie D., Strassle, Paula D., Reeder-Hayes, Katherine, Gallagher, Kristalyn K., Ollila, David W., Downs-Canner, Stephanie M., Spanheimer, Philip M.“…Women with small HER2+ breast cancers may have excellent prognosis with adjuvant single-agent chemotherapy and HER2-targeted therapy. …”
Publicado 2022
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3780por Zou, Yutian, Zheng, Shaoquan, Xie, Xinhua, Ye, Feng, Hu, Xiaoqian, Tian, Zhi, Yan, Shu-Mei, Yang, Lu, Kong, Yanan, Tang, Yuhui, Tian, Wenwen, Xie, Jindong, Deng, Xinpei, Zeng, Yan, Chen, Zhe-Sheng, Tang, Hailin, Xie, Xiaoming“…Intrinsic and acquired anti-HER2 resistance remains a major hurdle for treating HER2-positive breast cancer. …”
Publicado 2022
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