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54321“…RESULTS: There was no statistically significant difference between the two groups in age, T staging, N staging, hormone receptors, human epidermal receptor-2 (HER2), surgical methods, fractionated regimen, and chemotherapy conditions. …”
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54322“…A sex hormone test revealed that her estrogen level was significantly higher than normal, and other causes of hyperestrogenism had been excluded. …”
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54323“…This paper describes the process of developing an intervention where a complementary professional team meets the patient and his/her family altogether for 2.5 h. The consultation focus on clarifying the complex symptomatology and on problem solving. …”
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54324por Tanaka, Kazuyuki, Tanabe, Hiroki, Sato, Hiroki, Ishikawa, Chisato, Goto, Mitsuru, Yanagida, Naoyuki, Akabane, Hiromitsu, Yokohama, Shiro, Hasegawa, Kimiharu, Kitano, Yohei, Sugiyama, Yuya, Uehara, Kyoko, Kobayashi, Yu, Murakami, Yuki, Kunogi, Takehito, Sasaki, Takahiro, Takahashi, Keitaro, Ando, Katsuyoshi, Ueno, Nobuhiro, Kashima, Shin, Moriichi, Kentaro, Sato, Keisuke, Yuzawa, Sayaka, Tanino, Mishie, Taruiishi, Masaki, Sumi, Yasuo, Mizukami, Yusuke, Fujiya, Mikihiro, Okumura, Toshikatsu“…The responders were aged and were frequently diagnosed with intestinal type gastric cancer, including patients with a HER2‐positive status (27.3%) or microsatellite instability‐high (27.3%) status. …”
Publicado 2021
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54325“…Conclusions: Experiences with health professionals play a role in determining whether an individual manages his or her pain independently. Future research should explore the safety of those who do not seek care.…”
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54326por Mascia, Francesca, Mazo, Ilya, Alterovitz, Wei-Lun, Karagiannis, Konstantinos, Wu, Wells W., Shen, Rong-Fong, Beaver, Julia A., Rao, V. Ashutosh“…We investigated drug-induced autophagy in breast cancer cell lines with differing ER/PR/Her2 receptor status by exposing them to known but divergent autophagy inducers each with a unique molecular target, tamoxifen, trastuzumab, bortezomib or rapamycin. …”
Publicado 2022
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54327por Yang, Zhe, Ma, Yuting, Huang, Jiana, Xian, Jianzhong, Huang, Yin, Wu, Linbo, Zhu, WenLiang, Wang, Feng, Chen, Liang, Lin, Xiufang, Lin, Yubi“…The heterozygous SCN5Ap.R1865H was carried by her father and sister but not carried by I:2. II:1 carried with KCNH2 p.307_308del as a de novo mutation, but not existed in other family members. …”
Publicado 2021
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54328“…CASE PRESENTATION: We present a case of a 40-year-old hairdresser who suffered a fall off her moped in Spain, and simultaneously dislocated all three articulations around the knee. …”
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54329por Eida, Sato, Hotokezaka, Yuka, Sasaki, Miho, Hotokezaka, Hitoshi, Fujita, Shuichi, Katayama, Ikuo, Takagi, Yukinori, Sumi, Misa“…She was referred to our hospital with fast-growing painless swelling in her left mandible. Computed tomography revealed an exophytic juxtacortical mass eroding the lower part of the left mandible and lower mandibular cortex with a periosteal reaction. …”
Publicado 2021
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54330por Zhang, Biao, Li, Shuang, Sun, Zhen, Chen, Xu, Qi, Bing, Zhang, Qingkai, Zhang, Guixin, Shang, Dong“…We presented a case with NETs G1 of the hilar bile duct and the challenges for her treatment. CASE PRESENTATION: A 24-year-old woman was presented to our department with painless jaundice and pruritus, and the preoperative diagnosis was Bismuth type II hilar cholangiocarcinoma. …”
Publicado 2022
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54331por Brito, Cheila, Tomás, Ana, Azevedo, Ana, Esteves, Susana, Mafra, Manuela, Roque, Lúcia, Pojo, Marta“…In breast cancer (ER-positive, HER2-negative), these events represent a predictive biomarker of response to alpelisib. …”
Publicado 2022
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54332por Li, Liangliang, Li, Shuo, Qin, Shidong, Gao, Yu, Wang, Chao, Du, Jinghang, Zhang, Nannan, Chen, Yanbo, Han, Zhen, Yu, Yue, Wang, Fan, Zhao, Yashuang“…OPRM1 hypermethylation in tumor tissue was correlated with estrogen receptor (ER) (OR = 1.945, 95%CI: 1.262–2.996) and progesterone receptor (PR) (OR = 1.611, 95%CI: 1.069–2.427) negative status; in addition, OPRM1 hypermethylation in PBL DNA was associated with human epidermal growth factor receptor 2 (HER-2) negative status (OR = 3.673, 95%CI: 1.411–9.564). …”
Publicado 2021
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54333por Sanchez-Collado, Jose, Lopez, Jose J., Cantonero, Carlos, Jardin, Isaac, Regodón, Sergio, Redondo, Pedro C., Gordillo, Juan, Smani, Tarik, Salido, Gines M., Rosado, Juan A.“…Here we provide evidence for a heterogeneous expression of Orai2 among different breast cancer cell lines. In the HER2 and triple negative breast cancer cell lines SKBR3 and BT20, respectively, where the expression of Orai2 was greater, Orai2 modulates the magnitude of SOCE and sustain Ca(2+) oscillations in response to carbachol. …”
Publicado 2021
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54334“…Immunohistochemistry (IHC) of breast tumors with NE differentiation usually shows a hormone receptor (HR)-positive and human epidermal growth factor type 2 (HER2)-negative profile, so that hormonal therapy with cyclin-dependent kinase (CDK)4/6 inhibitors or other targeted agents would be reasonable treatment options. …”
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54335“…Extensive workup narrowed down her diagnosis as seronegative NMOSD. She had complete resolution of symptoms after treatment with concurrent plasma exchange (PLEX), high dose corticosteroids, and emtricitabine-tenofovir. …”
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54336“…After 2 months of peritoneal dialysis treatment, her renal function recovered and dialysis was stopped. …”
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54337por Fayed, Amel, Wahabi, Hayfaa A., Esmaeil, Samia, Elkouny, Roaa, Elmorshedy, Hala, Bakhsh, Hanadi“…BACKGROUND: Gestational weight gain (GWG) and prepregnancy obesity are garnering more attention as determining factors of pregnancy outcomes when it comes to the wellbeing of both the mother and her baby. This study was conducted to describe the pattern of GWG among participants of Riyadh Mother and Baby Multicenter Cohort Study (RAHMA) and to investigate the detrimental effects of excessive GWG and prepregnancy obesity on pregnancy outcomes. …”
Publicado 2022
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54338por Li, Haibo, Zhao, Aman, Xie, Min, Chen, Linqi, Wu, Haiying, Shen, Yiping, Wang, Hongying“…In addition, the qRT-PCR analysis verified an exon 5 microdeletion in the POR gene of the infant and her mother. While p.R457H is a well-known pathogenic mutation, the POR exon 5 deletion is absent from the public databases. …”
Publicado 2021
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54339por Kelly, Shannon E, Greene-Finestone, Linda S, Yetley, Elizabeth A, Benkhedda, Karima, Brooks, Stephen P J, Wells, George A, MacFarlane, Amanda JEnlace del recurso
Publicado 2021
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54340por Hurson, Amber N., Abubakar, Mustapha, Hamilton, Alina M., Conway, Kathleen, Hoadley, Katherine A., Love, Michael I., Olshan, Andrew F., Perou, Charles M., Garcia-Closas, Montserrat, Troester, Melissa A.“…We used two-stage polytomous logistic regression to evaluate risk factor heterogeneity due to RNA-based TP53 and/or ER, adjusting for each other and for PR, HER2, and grade. We then compared this with the results when using IHC-based TP53 classification. …”
Publicado 2022
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