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54701por Reinecke, Raphael, Reiländer, Annemarie, Seiler, Alexander, Koch, Christine, Voss, Martin“…CASE PRESENTATION: A 33-year-old female presented with a two-week history of severe ataxia of stance and gait, dysarthria, head tremor, myoclonus of the extremities and opsoclonus. Her past medical history was notable for a metastatic pancreatic neuroendocrine tumor, and she was subsequently diagnosed with paraneoplastic opsoclonus-myoclonus syndrome. …”
Publicado 2022
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54702“…The gene detection analyses indicated that the GFAP gene exon 1 c.262 C>T was caused by a heterozygous mutation, as both her parents were of the wild-type. The girl had no other abnormal manifestations except atonic seizures. …”
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54703por Calabrese, Alessandro, Santucci, Domiziana, Gravina, Michela, Faiella, Eliodoro, Cordelli, Ermanno, Soda, Paolo, Iannello, Giulio, Sansone, Carlo, Zobel, Bruno Beomonte, Catalano, Carlo, de Felice, Carlo“…A significant correlation was found between the risk of distant metastasis and tumor size, and the expression of PgR and HER2. Conclusions: We demonstrated a currently insufficient ability of the Deep Learning approach in predicting a distant metastasis status in patients with BC using CNNs.…”
Publicado 2022
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54704por Di Gregorio, Enza, Romiti, Chiara, Di Lorenzo, Antonino, Cavallo, Federica, Ferrauto, Giuseppe, Conti, Laura“…Their therapeutic effects were assessed both in vitro in triple-negative and HER2+ breast cancer cells, and in vivo in murine models. …”
Publicado 2022
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54706por Singh, Swathi, Gottumukkala, Sruthima Naga Venkata Satya, Konathala, Santosh Venkata Ramesh, Penmetsa, Gautami Subhadra, Dwarakanath, Chinnaswami Doraiswami, Bypalli, VivekEnlace del recurso
Publicado 2022
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54707por Ozsin Ozler, Cansu, Atalay, Cansu, Meral, Ece, Uzamis Tekcicek, Meryem, Guciz Dogan, Bahar, Ergin, EsraEnlace del recurso
Publicado 2022
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54708
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54709por Villanueva, Hugo, Wells, Gabrielle A., Miller, Malachi T., Villanueva, Mariana, Pathak, Ravi, Castro, Patricia, Ittmann, Michael M., Sikora, Andrew G., Lerner, Seth P.“…Patient tumor specimens acquired after chemotherapy treatment (post-NAC) and exhibiting NAC resistance were engrafted successfully on the CAM and displayed decreased tumor growth size and proliferation in response to treatment with a dual EGFR and HER2 inhibitor, but had no significant response to either CDK4/6 or FGFR inhibition. …”
Publicado 2022
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54710por Rabiei, Mohammad Mahdi, Ebrahimzadeh, Kaveh, Davoudi, Zahra, Bidari Zerehpoosh, Farahnaz, Javandoust Gharehbagh, Farid, Sedaghati, Roghayeh, Lotfollahi, Legha, Kalhor, Fatemeh, Alavi Darazam, Ilad“…She was referred to our hospital with a suspected diagnosis of nonfunctioning pituitary adenoma based on her presentation and brain MRI findings. She underwent trans-sphenoidal surgery (TSS). …”
Publicado 2023
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54711por Garofalo, M., Beudel, M., Dijk, J.M., Bonouvrié, L.A., Buizer, A.I., Geytenbeek, J., Prins, R.H.N., Schuurman, P.R., van de Pol, L.A.“…A significant amelioration of motor symptoms (65% on the Burke-Fahn-Marsden Dystonia Rating Scale) was observed postoperatively in the first patient and her personal therapeutic goals were achieved. DBS was previously reported in five patients with ADCY5 -related movement disorders, of which three showed objective improvement. …”
Publicado 2022
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54712por Asfaw, Yonathan Aliye, Huang, Helen, Taimur, Muhammad, Anand, Ayush, Poudel, Sujan, Garg, Tulika, Asfaw, Bethlehem Aliye, Abebe, Befekadu Molalegn, Akbariromani, Hanieh, Lazovic, Gavrilo, Cueva, Wilson“…We describe a unique case of a 16-year-old female who presented with convulsions, postictal confusion, and drowsiness followed by residual weakness of her extremities. She initially presented to the primary care center with headache, high-grade fever, and altered mental status and was empirically treated for pyogenic meningitis. …”
Publicado 2023
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54713por Xu, Qian, Chen, Yuan‐Yuan, Luo, Ying‐Hao, Zheng, Jin‐Sen, Lin, Zai‐Huan, Xiong, Bin, Wang, Lin‐Wei“…Multivariable analysis identified age, T stage, N status, histological grade, ER status, HER‐2 gene, and TSR as potential risk predictors, which were included in the nomogram. …”
Publicado 2022
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54714por Wen, Xiao-Ling, Wang, Yao-Zi, Zhang, Xia-Lin, Tu, Jia-Qiang, Zhang, Zhi-Juan, Liu, Xia-Xia, Lu, Hai-Yan, Hao, Guo-Ping, Wang, Xiao-Huan, Yang, Lin-Hua, Zhang, Rui-Juan“…The patient was treated with imiglucerase replacement therapy, and her condition was stable. CONCLUSION: The p.L483P/p.S310G novel compound heterozygous mutation underlies type 1 GD and likely affects GCase protein function. …”
Publicado 2022
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54715por Singhal, Sandeep K., Al-Marsoummi, Sarmad, Vomhof-DeKrey, Emilie E., Lauckner, Bo, Beyer, Trysten, Basson, Marc D.“…SLFN12-overexpressing xenografts increased less aggressive BC markers, HER2 receptors ERBB2 and EGFR expression, which are not detectable by immunostaining in TNBC. …”
Publicado 2023
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54716por Chen, Huihui, Jin, Jingjing, Cheng, Mei Juan, He, Lei, Zhou, Wei, Guo, Liping, Niu, Zhe Zhe, Liang, Xiang Nan, Zhu, Rong Fang, Bai, Yaling, Xu, Jin Sheng“…OUTCOMES: The patient was followed up for 1 year. On the last visit, her serum creatinine decreased to 103.5μmol/L, anti-GBM antibody remained negative, and proteinuria and hematuria disappeared. …”
Publicado 2023
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54717por Alshammari, Fatemah OFO, Satari, Anas O., Aljabali, Ahmed S., Al-mahdy, Yanal S., Alabdallat, Yasmeen J., Al-sarayra, Yahya M., Alkhojah, Mohammad A., Alwardat, Abdel rahman M., Haddad, Mansour, Al-sarayreh, Sameeh A., Al-saraireh, Yousef M.“…Importantly, GPC3 expression was found more often in tumours that tested positive for the expression of hormone receptors and human epidermal growth factor receptor 2 (HER2), indicating more favourable histological subtypes of breast cancer. …”
Publicado 2022
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54718por Nevard, Rory P., Pant, Sameer D., Broster, John C., Norman, Scott T., Stephen, Cyril P.“…Following centuries of varying levels of domestication processes, the behavior of the bovine cow has altered from that of her original wild ungulate ancestors, although many maternal instincts have remained unchanged. …”
Publicado 2022
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54719por Oranratnachai, Songporn, Yamkaew, Watchalawalee, Tunteeratum, Atchara, Sukarayothin, Thongchai, Iemwimangsa, Nareenart, Panvichien, Ravat“…Two of these tumors were HER2‐positive luminal‐B, and the triple‐negative subtype was not detected. …”
Publicado 2022
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54720por HomayunHosseini, Atefeh Zahra“…The disease's complications reduce the quality of life in patients by creating physical, psychological, social and economic problems for the patient and his/her family and reducing the patient's individual and social functioning. …”
Publicado 2023
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