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54761“…Pathogenic variants of the tumor suppressor genes BRCA1 and BRCA2 are responsible for the majority of hereditary breast cancers; they are also becoming increasingly important to identify whether patients are suitable for targeted therapy with poly ADP-ribose polymerase inhibitors (PARPi). Patients with HER2-negative breast cancer and BRCA1/2 germline mutations can benefit significantly from PARPi therapy, and the findings of the OlympiAD and the EMBRACA phase III clinical trials for regulatory approval were recently expanded by the addition of the most recent OlympiA data on the treatment of patients with early disease and a high risk of recurrence. …”
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54762por Nimbalkar, Vidya P., Rajarajan, Savitha, V P, Snijesh, Alexander, Annie, Kaluve, Rohini, Selvam, Sumithra, Ramesh, Rakesh, B S, Srinath, Prabhu, Jyothi S.“…Premenopausal BC had a higher proportion of HER2 amplified and triple negative breast cancer (TNBC) tumors (p = 0.012). …”
Publicado 2023
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54763“…One month ago, the patient fell in her bathroom. Physical examination demonstrated locking knee, positive McMurray test. …”
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54764por Brock, James“…On further discussion when I reviewed her she described stiffness and pain in axial skeleton in keeping with PMR. …”
Publicado 2019
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54765por Ahearn, Thomas U., Zhang, Haoyu, Michailidou, Kyriaki, Milne, Roger L., Bolla, Manjeet K., Dennis, Joe, Dunning, Alison M., Lush, Michael, Wang, Qin, Andrulis, Irene L., Anton-Culver, Hoda, Arndt, Volker, Aronson, Kristan J., Auer, Paul L., Augustinsson, Annelie, Baten, Adinda, Becher, Heiko, Behrens, Sabine, Benitez, Javier, Bermisheva, Marina, Blomqvist, Carl, Bojesen, Stig E., Bonanni, Bernardo, Børresen-Dale, Anne-Lise, Brauch, Hiltrud, Brenner, Hermann, Brooks-Wilson, Angela, Brüning, Thomas, Burwinkel, Barbara, Buys, Saundra S., Canzian, Federico, Castelao, Jose E., Chang-Claude, Jenny, Chanock, Stephen J., Chenevix-Trench, Georgia, Clarke, Christine L., Collée, J. Margriet, Cox, Angela, Cross, Simon S., Czene, Kamila, Daly, Mary B., Devilee, Peter, Dörk, Thilo, Dwek, Miriam, Eccles, Diana M., Evans, D. Gareth, Fasching, Peter A., Figueroa, Jonine, Floris, Giuseppe, Gago-Dominguez, Manuela, Gapstur, Susan M., García-Sáenz, José A., Gaudet, Mia M., Giles, Graham G., Goldberg, Mark S., González-Neira, Anna, Alnæs, Grethe I. Grenaker, Grip, Mervi, Guénel, Pascal, Haiman, Christopher A., Hall, Per, Hamann, Ute, Harkness, Elaine F., Heemskerk-Gerritsen, Bernadette A. M., Holleczek, Bernd, Hollestelle, Antoinette, Hooning, Maartje J., Hoover, Robert N., Hopper, John L., Howell, Anthony, Jakimovska, Milena, Jakubowska, Anna, John, Esther M., Jones, Michael E., Jung, Audrey, Kaaks, Rudolf, Kauppila, Saila, Keeman, Renske, Khusnutdinova, Elza, Kitahara, Cari M., Ko, Yon-Dschun, Koutros, Stella, Kristensen, Vessela N., Krüger, Ute, Kubelka-Sabit, Katerina, Kurian, Allison W., Kyriacou, Kyriacos, Lambrechts, Diether, Lee, Derrick G., Lindblom, Annika, Linet, Martha, Lissowska, Jolanta, Llaneza, Ana, Lo, Wing-Yee, MacInnis, Robert J., Mannermaa, Arto, Manoochehri, Mehdi, Margolin, Sara, Martinez, Maria Elena, McLean, Catriona, Meindl, Alfons, Menon, Usha, Nevanlinna, Heli, Newman, William G., Nodora, Jesse, Offit, Kenneth, Olsson, Håkan, Orr, Nick, Park-Simon, Tjoung-Won, Patel, Alpa V., Peto, Julian, Pita, Guillermo, Plaseska-Karanfilska, Dijana, Prentice, Ross, Punie, Kevin, Pylkäs, Katri, Radice, Paolo, Rennert, Gad, Romero, Atocha, Rüdiger, Thomas, Saloustros, Emmanouil, Sampson, Sarah, Sandler, Dale P., Sawyer, Elinor J., Schmutzler, Rita K., Schoemaker, Minouk J., Schöttker, Ben, Sherman, Mark E., Shu, Xiao-Ou, Smichkoska, Snezhana, Southey, Melissa C., Spinelli, John J., Swerdlow, Anthony J., Tamimi, Rulla M., Tapper, William J., Taylor, Jack A., Teras, Lauren R., Terry, Mary Beth, Torres, Diana, Troester, Melissa A., Vachon, Celine M., van Deurzen, Carolien H. M., van Veen, Elke M., Wagner, Philippe, Weinberg, Clarice R., Wendt, Camilla, Wesseling, Jelle, Winqvist, Robert, Wolk, Alicja, Yang, Xiaohong R., Zheng, Wei, Couch, Fergus J., Simard, Jacques, Kraft, Peter, Easton, Douglas F., Pharoah, Paul D. P., Schmidt, Marjanka K., García-Closas, Montserrat, Chatterjee, Nilanjan“…METHODS: Among 106,571 invasive breast cancer cases and 95,762 controls of European ancestry with data on 173 breast cancer variants identified in previous GWAS, we used novel two-stage polytomous logistic regression models to evaluate variants in relation to multiple tumor features (ER, progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2) and grade) adjusting for each other, and to intrinsic-like subtypes. …”
Publicado 2022
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54766“…CASE REPORT - CASE DESCRIPTION: A 59-year-old Caucasian female presented in January 2018 to the dermatologist with a 6-month history of itchy, dry, flaky skin around her eyes with periorbital erythema which later progressed to fixed periorbital oedema. …”
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54767por Bach, Johann Sebastian, 1685-1750Tabla de Contenidos: “…. : Organ concertos, BWV 592-596 -- Tocata an fugue in D minor BWV 565 ; Fantasia in G major BWV 572 ; Canonic variations on "Vom Himmel hoch, da komm'ich her" BWV 769 ; Prelude and fugue in D major BWV 532 ; Pastorale in F major BWV 590 ; Prelue and fugue in E{flat} major "ST. …”
Publicado 1988
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54768por Schröder, Bernd“…PRAISE FOR THE FIRST EDITION "The author has done the field a service by producing an excellent text strong in the presentation of certain topological aspects of the underlying diagrams, e.g., which should serve the developing community and field well and which can be recommended without reservations as one of the volumes which should grace a poseteer's library whether she is interested only or mainly in the theory of these objects or has directed her gaze towards applications. As a sourcebook of ideas and understanding it will make its mark. …”
Publicado 2016
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54769por Gemme, Giulia“…She is working in the field of quantum thermodynamics, focusing her study on quantum batteries, namely miniaturized devices exploiting non-classical features to efficiently store, transfer and release energy on-demand.…”
Publicado 2023
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54770por Walsh, Catherine“…A lo largo de este recorrido, la decolonialidad experimentada a través de la militancia en movimientos y comunidades afrodescendientes e indígenas se ha convertido en un significante que posibilita la construcción de otras formas de ser y de pensar en y con el mundo, abriendo grietas y fisuras en los órdenes políticos y epistémicos imperantes.Palabras-claveDecolonialidad, Pedagogía crítica, Movimientos sociales, Investigación militante AbstractIn these pedagogical notes that combine biographical and political issues, Catherine Walsh reflects on her career as an intellectual activist, educator and facilitator. …”
Publicado 2015
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54771por ARBOLEDA SEPULVEDA, ORLANDO“…HOWEVER, EACH INDIVIDUAL IS RESPONSIBLE FOR THIS OR HER OWN FUTURE, AS THE OWNER OF THE MEANS OF PRODUCTION. …”
Publicado 2003
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54772por Díaz Méndez, Marcela Mabel“…Advirtiendo, además, en su correlación con el poder, posibles cambios de paradigmas socio-jurídicos y posibles grietas o fracturas al biopoder de los Estados, especialmente, en Latinoamérica.Abstract: According to the reasoning expressed by Judith Butler, in her book Fearless: Forms of Resistance to Today's Violence. …”
Publicado 2023
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54773por Apodaca Orozco, Aby Ariana, Chan Barocio, Nadia Lourdes, Córdova Cárdenas, Gilberto Manuel“…The objective of this research was to evaluate, through a WISC-IV, an adolescent with mild cognitive impairment, to develop an intervention program in order to reinforce her cognitive abilities. This research carried out within a mixed approach with a non- experimental longitudinal – trend. …”
Publicado 2019
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54774por Taiwo, Adekunle Bamidele, Fatunla, Odunayo Adebukola, Ogundare, Olatunde Ezra, Oluwayemi, Oludare Isaac, Babatola, Adefunke Olarinre, Ajite, Adebukola Bidemi, Ajibola, Ayotunde Emmanuel, Olajuyin, Adebola, Sola-Oniyide, Boluwatife, Olatunya, Oladele Simeon“…The affordability of health care services by households within a country is determined by the health care financing methods used by her citizens. In accordance with World Health Organization (WHO), health services must be delivered equitably and without imposing financial hardship on the citizens. …”
Publicado 2023
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54775“…The neonate carried in compound heterozygosity the TNXA/TNXB chimeric gene complex (termed CAH-X CH-1) that results in a contiguous CYP21A2 and TNXB deletion and in her second allele the pathogenic IVS2-13A/C > G (c.655A/C > G) in CYP21A2. …”
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54776por St. Cyr, Kate, Liu, Aihua, Plouffe, Rachel A., Nouri, Maede S., Forchuk, Callista A., Wanklyn, Sonya G., Bird, Brian M., Fikretoglu, Deniz, Mahar, Alyson L., Nazarov, Anthony, Richardson, J. DonEnlace del recurso
Publicado 2022
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54777“…A 35-year-old female, Gravida 2 Para 1 at 31 weeks age of gestation (AOG) who underwent cesarean section for nonreassuring fetal status in 2019, was admitted for severe COVID-19 infection presenting with dyspnea. During her hospitalization, she developed progressive dyspnea from worsening of COVID-19 infection. …”
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54778por Zhang, Xudong, Cui, Hao, Hu, Nana, Han, Peng, Fan, Wei, Wang, Panting, Zuo, Xiaoxuan, Zhao, Dantong, Huang, He, Li, Shuo, Kong, Hanqing, Peng, Fuhui, Tian, Jiawei, Zhang, Lei“…AR + could be a sign of a better prognosis in overall breast cancer (p < 0.001), as well as in human epidermal growth factor receptor 2 (HER2) overexpression and Luminal B subtypes (p = 0.001 and 0.025). …”
Publicado 2023
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54779por Sun, Liang, Tian, Haowen, Ge, Hongwei, Tian, Juan, Lin, Yuxin, Liang, Chang, Liu, Tang, Zhao, Yiping“…There were 160 cases in total, with 84 cases of luminal type (luminal A and luminal B and 76 cases of non-luminal type (HER 2 overexpressing and triple negative). Patients were grouped according to thresholds of nodule sizes of 20 mm and age at menarche of 14 years. …”
Publicado 2023
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54780por Mosca, Lucia Luciana, Continisio, Grazia Isabella, De Lucia, Natascia, Gigante, Elena, Guerriera, Carmela, Maldonato, Nelson Mauro, Moretto, Enrico, Ragozzino, Ottavio, Rosa, Veronica, Scognamiglio, Chiara, Stanzione, Roberta, Cantone, Daniela“…Such studies seem to be significantly increasing and reflect the emerging need to have to consider the human being in his or her complexity, whose existential and personal dimensions can no longer be traced to classification systems that are divorced from the epochal reference. …”
Publicado 2023
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