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55041Ki67, chemotherapy response, and prognosis in breast cancer patients receiving neoadjuvant treatmentpor Fasching, Peter A, Heusinger, Katharina, Haeberle, Lothar, Niklos, Melitta, Hein, Alexander, Bayer, Christian M, Rauh, Claudia, Schulz-Wendtland, Ruediger, Bani, Mayada R, Schrauder, Michael, Kahmann, Laura, Lux, Michael P, Strehl, Johanna D, Hartmann, Arndt, Dimmler, Arno, Beckmann, Matthias W, Wachter, David L“…METHODS: Ki67 was stained routinely from core biopsies in 552 patients directly after the fixation and embedding process. HER2/neu, estrogen and progesterone receptors, and grading were also assessed before treatment. …”
Publicado 2011
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55042Expression of recombinant multi-coloured fluorescent antibodies in gor (-)/trxB(- )E. coli cytoplasmpor Markiv, Anatoliy, Beatson, Richard, Burchell, Joy, Durvasula, Ravi V, Kang, Angray S“…The insertion of monomeric fluorescent protein derived from either Discosoma or Aequorea in-between the variable regions of anti-p185(HER2-ECD )antibody 4D5-8 resulted in optimal V(H)/V(L )interface interactions to create soluble coloured antibodies each with a single binding site, with isoelectric points of 6.5- 6. …”
Publicado 2011
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55043“…During the 12-week study period, each woman in the intervention group wore a pedometer and recorded her daily step count. The women were advised to increase their steps by 500 per week until they achieved the first target of 5000 steps per day and then continued to increase it to minimum of 10,000 steps per day by the end of 12(th )week. …”
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55044por Schubert, Christian, Geser, Willi, Noisternig, Bianca, Fuchs, Dietmar, Welzenbach, Natalie, König, Paul, Schüßler, Gerhard, Ocaña-Peinado, Francisco M., Lampe, Astrid“…A healthy 25-year-old woman collected her entire urine over a period of 63 days in 12-h intervals (126 measurements) to determine cortisol and neopterin (immune activation marker) levels. …”
Publicado 2012
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55045por Khan, Ataur R., Al-Abdul Lateef, Zaki N., Al Aithan, Mohammad A., Bu-Khamseen, Montaser A., Ibrahim, Ibrahim Al, Khan, Shabbir A.“…Any patient who had been prescribed optimum treatment and was properly advised on diet and exercise for his / her diabetes, but did not follow the medical advice, with Hb1AC of more than 7% at the time of interview, was considered as non-compliant. …”
Publicado 2012
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55046por Akahane, T, Nagata, M, Matsumoto, T, Murayama, N, Isaka, A, Kameda, T, Fujita, M, Oana, K, Kawakami, Y“…METHODOLOGY: Exudates from the open wound of her dog-bite site, together with the saliva of the dog were submitted for bacteriological examination. …”
Publicado 2011
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55047por Sword, Wendy, Heaman, Maureen I, Brooks, Sandy, Tough, Suzanne, Janssen, Patricia A, Young, David, Kingston, Dawn, Helewa, Michael E, Akhtar-Danesh, Noori, Hutton, Eileen“…A recurrent theme woven throughout the data reflected the importance of a meaningful relationship between a woman and her prenatal care provider that was characterized by trust. …”
Publicado 2012
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55048por Gao, Yuanfeng, Li, Cuilan, Liu, Wenling, Wu, Robby, Qiu, Xiaoliang, Liang, Ruijuan, Li, Lei, Zhang, Li, Hu, Dayi“…RESULTS: We identified 7 KCNQ1 mutations. c.1032_1117dup (p.Ser373TrpfsX10) and c.1319delT (p.Val440AlafsX26) were novel, causing JLNS in a 16-year-old boy with a QTc (QT interval corrected for heart rate) of 620 ms and recurrent syncope. c.605-2A>G and c.815G>A (p.Gly272Asp) caused JLNS in a 12-year-old girl and her 5-year-old brother, showing QTc of 590 to 600 ms and recurrent syncope. …”
Publicado 2012
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55049por Ruotsalainen, Pekka Sakari, Blobel, Bernd Gerhard, Seppälä, Antto Veikko, Sorvari, Hannu Olavi, Nykänen, Pirkko Anneli“…The person shall have the right to verify the level of trust of any system which collects or processes his or her health information. Principles require that any stakeholder or system collecting or processing health data must support transparency and shall publish its trust and privacy attributes and even its domain specific policies. …”
Publicado 2012
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55050por Kheir, Nadir M, Sandridge, Amy L, Hayder, Sara A, Al-Ismail, Muna S, Al-Rawi, Fadhila“…Data collected from both groups included related to the child (e.g. the child’s date of birth, his/her relation to the caregiver, number of siblings, number of hours of sleep in a day, number of hours spent watching television or videos prior to age 3, time spent indoors prior to age 3, absenteeism from school, and use of a nanny to care for the child) and to the caregiver (education level, profession, level of consanguinity using the phylogram method). …”
Publicado 2012
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55051por Welch, Martha G, Hofer, Myron A, Brunelli, Susan A, Stark, Raymond I, Andrews, Howard F, Austin, Judy, Myers, Michael M“…Our primary objective is to determine whether repeated engagement of the mother and her infant in the intervention's calming activities will improve the infant's developmental trajectory with respect to multiple outcomes. …”
Publicado 2012
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55052por Kim, Jeong Eun, Ahn, Heui June, Ahn, Jin-Hee, Yoon, Dok Hyun, Kim, Sung-Bae, Jung, Kyung Hae, Gong, Gyung-Yub, Kim, Mi-Jung, Son, Byung Ho, Ahn, Sei Hyun“…TNBC was defined as a primary tumor negative for estrogen and progesterone receptors (Allred scores <3/8) and for HER2/neu (0-1+ by immunohistochemistry). RESULTS: Of the 554 patients with stage I breast cancer, 78 (14.1%) had TNBC. …”
Publicado 2012
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55053por Onwujekwe, Obinna E, Ogbonna, Chinwe, Uguru, Nkoli, Uzochukwu, Benjamin SC, Lawson, Agathe, Ndyanabangi, Bannet“…The targeted respondent in a household was a female primary care giver of child bearing age (usually the wives), or in her absence, another female household member of child bearing age. …”
Publicado 2012
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55054por Momi, Navneet, Ponnusamy, Moorthy P., Kaur, Sukhwinder, Rachagani, Satyanarayana, Kunigal, Sateesh S, Chellappan, Srikumar, Ouellette, Michel M, Batra, Surinder K“…Additionally, we demonstrated that nicotine-mediated MUC4 up-regulation promotes the PC cell migration through the activation of the downstream effectors such as HER2, c-Src and FAK; this effect was attenuated by shRNA-mediated MUC4 abrogation, further implying that these nicotine-mediated pathological effects on PC cells are MUC4 dependent. …”
Publicado 2012
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55055por Lee, Yi Fang, Miller, Lance David, Chan, Xiu Bin, Black, Michael A, Pang, Brendan, Ong, Chee Wee, Salto-Tellez, Manuel, Liu, Edison T, Desai, Kartiki V“…RESULTS: JMJD6 was expressed at highest levels in tumors associated with worse outcomes, including ER- and basal-like, Claudin-low, Her2-enriched, and ER(+ )Luminal B tumors. High nuclear JMJD6 protein was associated with ER negativity, advanced grade, and poor differentiation in tissue microarrays. …”
Publicado 2012
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55056por Yan, Max, Xu, Huiling, Waddell, Nic, Shield-Artin, Kristy, Haviv, Izhak, McKay, Michael J, Fox, Stephen B“…No correlation was found between RAD21 expression and grade, size, or lymph node, ER, or HER2 status (all P > 0.05). As for sporadic breast cancers, RAD21 expression correlated with shorter survival in grade 3 (P = 0.009) and but not in grade 1 (P = 0.065) or 2 cancers (P = 0.090). …”
Publicado 2012
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55057“…Also, each individual’s acuity limit was estimated by fitting his or her data with a model and extrapolating to find the spatial frequency corresponding to 100% contrast. …”
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55058“…The most common reasons for not testing were: not being ready/feeling scared/needing to think about it (34.1%); knowing his/her status (22.6%), being HIV-positive (18.5%), and not feeling at risk of having or acquiring HIV (10.1%). …”
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55059“…CONCLUSION: Most of the study participants in this study knew that HIV could be transmitted from an infected mother to her baby. There should be well functioning and accessible health facilities with Prevention of mother to child transmission service in the country especially in the rural areas.…”
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55060por Rais, Ghizlane, Raissouni, Soundouss, Aitelhaj, Meryem, Rais, Fadoi, Naciri, Sara, Khoyaali, Siham, Abahssain, Halima, Bensouda, Youssef, Khannoussi, Basma, Mrabti, Hind, Errihani, Hassan“…BACKGROUND: Triple-negative breast cancer (TNBC) is defined by the lack of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER-2) expression. This is an aggressive malignancy with a poor prognosis despite the high rates of response to chemotherapy. …”
Publicado 2012
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