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55521“…Patient was then treated with bisphosphonates for 5 years and her DEXA scan T score of (-) 2.9 at the radius never improved. …”
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55522“…All symptoms had resolved, and she had multiple screening including Ultrasounds and AFP. All her images and AFP remained normal. Then at the age of 5 years, she started to have new pubic hair and acne. …”
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55523“…After the surgery, calcium and vitamin D supplementation were initiated. Her calcium levels remained stable throughout the hospital course. …”
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55524por Zhang, Yi-Chen, Chen, Zhi-Hong, Zhang, Xu-Chao, Xu, Chong-Rui, Yan, Hong-Hong, Xie, Zhi, Chuai, Shao-Kun, Ye, Jun-Yi, Han-Zhang, Han, Zhang, Zhou, Bai, Xiao-Yan, Su, Jian, Gan, Bin, Yang, Jin-Ji, Li, Wen-Feng, Tang, Wei, Luo, Feng Roger, Xu, Xiao, Wu, Yi-Long, Zhou, Qing“…Other EGFR-independent resistance mechanisms involved CDKN2A, MET, PIK3CA, HER2, TP53, Rb1 and small-cell lung cancer transformation. …”
Publicado 2019
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55525“…Every participant described the relationship with his/her PAD as positive, suggesting that a successful working partnership does not require the dog to have been bred or raised specifically for the role. …”
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55526por de Wolff, Mie Gaarskjaer, Backhausen, Mette Grønbæk, Iversen, Mette Langeland, Bendix, Jane Marie, Rom, Ane Lilleøre, Hegaard, Hanne Kristine“…BACKGROUND: Maternal smoking is still a major public health problem posing the risk of several negative health outcomes for both the pregnant woman and her offspring. The prevalence of maternal smoking in Denmark and other high-income countries has decreased continuously since the 1980s, and a prevalence below 10% of women who continue to smoke during pregnancy has been reported in studies after 2010. …”
Publicado 2019
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55527por Beck, Tim N., Boumber, Yanis A., Aggarwal, Charu, Pei, Jianming, Thrash-Bingham, Catherine, Fittipaldi, Patricia, Vlasenkova, Ramillya, Rao, Chandra, Borghaei, Hossein, Cristofanilli, Massimo, Mehra, Ranee, Serebriiskii, Ilya, Alpaugh, R. Katherine“…Two methods were used for CTC capture: the standard epithelial cell adhesion molecule (EpCam) CellSearch kit (unicapture) and EpCAM plus HER2, EGFR and MUC-1 specific combined ferrofluid capture (quadcapture). …”
Publicado 2019
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55528por Strafella, Claudia, Campoli, Giulia, Galota, Rosaria Maria, Caputo, Valerio, Pagliaroli, Giulia, Carboni, Stefania, Zampatti, Stefania, Peconi, Cristina, Mela, Julia, Sancricca, Cristina, Primiano, Guido, Minozzi, Giulietta, Servidei, Serenella, Cascella, Raffaella, Giardina, Emiliano“…The mother was positive for c.550delA (CAPN3) and c.550C>T (LMNA), suggesting thereby a possible genetic explanation for her cardiovascular problems. Segregation analysis, therefore, confirmed the inheritance pattern of the variants carried by the proband and highlighted a familiarity for cardiomyopathy which should not be neglected. …”
Publicado 2019
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55529por Rosas, Marina Araújo, Cordeiro, Tattiana Dias de Carvalho, da Silva, Tatiana de Paula Santana, Caldas, Ada Salvetti Cavalcanti, Ribeiro, Carlos Eduardo de Souza Leão, Marinho, Manoel Henrique da Nóbrega, Lima, Murilo Duarte da Costa, Vasconcelos, Selene Cordeiro“…Self-efficacy has been referenced as an important aspect to the prognosis of mood disorders by conferring co-responsibility to the affected individual to face his/her health problems. Several assessment tools are found in the literature for measuring self-efficacy, but it is not yet clear which of these measures are more applicable to individuals with mood disorders, particularly depression. …”
Publicado 2019
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55530por Addis, Maria Filippa, Cubeddu, Tiziana, Pilicchi, Ylenia, Rocca, Stefano, Piccinini, Renata“…The goat had never shown clinical signs of mastitis or other diseases. Her right half-udder milk was positive to L. monocytogenes in two consecutive samples collected one week apart, as demonstrated by bacterial culture and molecular analysis. …”
Publicado 2019
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55531“…For example, a woman aged 50 years who reported high affective well-being could expect to live 6 years longer than a woman of similar age with low well-being; 31.4 of her remaining years (95% CI, 30.5-31.9 years) would be likely to be free of disability, compared with 20.8 years (95% CI, 20.1-22.1 years) for a woman with low affective well-being. …”
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55532por Li, Jialin, Chattopadhyay, Kaushik, Xu, Miao, Chen, Yanshu, Hu, Fangfang, Wang, Xingzhen, Li, Li“…Polypharmacy prescription was defined as the simultaneous prescription of ≥5 medicines by the clinician at the time of discharge for daily usage by the patient as part of his/her long-term treatment plan. RESULTS: The study inclusion criteria were satisfied by 3370 T2DM patients. …”
Publicado 2019
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55533por Chowdhary, Mudit, Sen, Neilayan, Chowdhary, Akansha, Usha, Lydia, Cobleigh, Melody A., Wang, Dian, Patel, Kirtesh R., Barry, Parul N., Rao, Ruta D.“…PURPOSE: Palbociclib is a selective cyclin-dependent kinase 4/6 inhibitor approved for metastatic ER+/HER2- breast cancer. Preclinical evidence suggests a possible synergistic effect of palbociclib when combined with radiation therapy (RT); however, the toxicity of this pairing is unknown. …”
Publicado 2019
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55534por Talebi, Mehrdad, Yahya Vahidi Mehrjardi, Mohammad, Kalhor, Kambiz, Dehghani, Mohammadreza“…Following next generation sequencing determined one homozygous mutation in CPS1 gene and also this mutation was determined in her parents. The identified mutation was c.2758G [Formula: see text] C; p.Asp920His, in the 23 exon of CPS1. …”
Publicado 2019
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55535por Frick, Elisabet, Gudjonsson, Thorkell, Eyfjord, Jorunn, Jonasson, Jon, Tryggvadóttir, Laufey, Stefansson, Olafur, Sigurdsson, Stefan“…Tissue microarrays (TMAs) were available for ER (n = 436), PR (n = 436), HER-2 (N = 258) and Ki67 (n = 248). MiR-190b had reduced promoter methylation in estrogen receptor-positive breast cancers (P = 1.02e–12, Median values: ER+ 24.3, ER– 38.26) and miR-190b’s expression was up-regulated in a correlative manner (P = 1.83e–06, Spearman’s rho –0.62). …”
Publicado 2019
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55536por Kuo, Chih-Yu, Lin, Shing-Huey, Lee, Kuan-Der, Cheng, Sho-Jen, Chu, Jan-Show, Tu, Shih-Hsin“…CASE PRESENTATION: We report a rare case of a 51-year-old woman who had a giant malignant phyllodes tumor with heterologous sarcomatous differentiation in her right breast. The tumor was 19.43 × 12.98 × 21.47 cm. …”
Publicado 2019
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55537por Liang, Yayun, Besch-Williford, Cynthia, Cook, Matthew T, Belenchia, Anthony, Brekken, Rolf A, Hyder, Salman M“…BACKGROUND: Approximately 15–20% of all human breast cancers are classified as triple-negative because they lack estrogen and progesterone receptors and Her-2-neu, which are commonly targeted by chemotherapeutic drugs. …”
Publicado 2019
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55538por Josey, Michele J., McCullough, Lauren E., Hoyo, Cathrine, Williams-DeVane, ClarLynda“…Maternal obesity can affect the weight status of her offspring through intrauterine mechanisms like excessive gestational weight gain (GWG). …”
Publicado 2019
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55539por Zhang, Wenfeng, Xia, Ding, Li, Zhangyun, Zhou, Tao, Chen, Tingting, Wu, Zhengping, Zhou, Weihua, Li, Zilun, Li, Longkun, Xu, Jie“…Triple-negative breast cancer (TNBC), defined as a tumor subtype that lacks ER, PR, and HER2, shows a poor prognosis due to its aggressive tumor biology and limited treatment options. …”
Publicado 2019
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55540“…One patient experienced a modest improvement in her somatic arousal, insomnia severity, and fatigue with autotitrating nasal continuous positive airway pressure, but the other two did not tolerate nasal continuous positive airway pressure. …”
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