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55581“…The drug was prescribed by her gynecologist due to the presence of uterine myomas. …”
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55582por Koren, Gideon, Souroujon, Daniel, Shaul, Ran, Bloch, Allon, Leventhal, Ariel, Lockett, Jason, Shalev, Varda“…The App. invites the user to describe her/ his main symptom or several symptoms, and this prompts a series of questions along the path developed by the algorithm, based on the analysis of 70 million patients’ visits to their physicians. …”
Publicado 2019
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55583por Denkiewicz, Michał, Saha, Indrajit, Rakshit, Somnath, Sarkar, Jnanendra Prasad, Plewczynski, Dariusz“…The four-star miRNAs provide 95% average accuracy, while in case of one-star miRNAs 81% accuracy is achieved for HER2-Enriched. Differences in expression of miRNAs between cancer stages is also analyzed, and a subset of eight miRNAs is found, for which expression is increased in stage II relative to stage I, including hsa-miR-10b-5p, which contributes to breast cancer metastasis. …”
Publicado 2019
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55584“…Univariate analysis was conducted with log-rank test between OS and the potential characteristics including gender, age, PS status, primary tumor lesion, Her-2 status, and previous lines of treatment. Toxicities were assessed with the criteria of National Cancer Institute Common Toxicity Criteria (NCI CTC) version 4.0. …”
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55585por Kotecha, Shreeya, Lebot, Marie N., Sukkarn, Bhudsaban, Ball, Graham, Moseley, Paul M., Chan, Stephen Y., Green, Andrew R., Rakha, Emad, Ellis, Ian O., Martin, Stewart G., Storr, Sarah J.“…DARPP-32 expression was determined using immunohistochemistry in two independent cohorts of early stage invasive breast cancer patients (discovery n = 1352; validation n = 1655), and 112 HER2 positive breast cancer patients treated with trastuzumab and adjuvant chemotherapy. …”
Publicado 2019
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55586“…ER/PR was positive in 46(41.1%), HER-2/neu positive in 31 (27.6%). On staging breast carcinoma was metastatic in 13(11.6%) with liver, lung and bone in 4 (3.5%), 3 (2.7%) and 6 (5.3%) respectively. …”
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55587por Huang, Haipeng, Mikami, Yukiko, Shigematsu, Kosuke, Uemura, Nozomi, Shinsaka, Mamiko, Iwatani, Ayaka, Miyake, Fumihito, Kabe, Kazuhiko, Takai, Yasushi, Saitoh, Masahiro, Baba, Kazunori, Seki, Hiroyuki“…She had a history of hypothyroidism but was prescribed orally administered levothyroxine (50 μg/day) prior to conception and was euthyroid. Her ultrasound scan prior to visiting our hospital revealed fetal omphalocele, heavy for date, and polyhydramnios. …”
Publicado 2019
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55588por Gobaru, Mizuki, Ashida, Kenji, Yoshinobu, Satoko, Nagayama, Ayako, Kabashima, Masaharu, Iwata, Shimpei, Hasuzawa, Nao, Tsuruta, Munehisa, Wada, Nobuhiko, Nakayama, Hitomi, Motomura, Seiichi, Tajiri, Yuji, Nomura, Masatoshi“…This combination of type 1 diabetes mellitus, myasthenia gravis, and Hashimoto disease led to a diagnosis of APS3. Her HLA serotype was A24; B46/54; DR4/9; DQ8/9, and genotype was A*24: 02; B*46: 01: 01/54: 01: 01; C*01: 02; DRB1*04: 06/09: 01: 02; DQB1*03: 02: 01/03: 03: 02; and DQA1*03: 01/03: 02: 01. …”
Publicado 2019
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55589por Abdel-Razeq, Hikmat, Almasri, Hanan, Abdel Rahman, Fadwa, Abdulelah, Hazem, Abu Nasser, Mahmoud, Salam, Mourad, Al-Dairi, Ammer, Natour, Osama, Rimawi, Dalia“…Patients with nonmetastatic disease had poor pathological features, including node-positivity (66.9%), grade III (51.4%), lymphovascular invasion (48.6%) and positive HER2 (31.5%). Breast-conserving surgery was performed on 32.9%, and only 36.5% of women had breast-reconstruction surgery. …”
Publicado 2019
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55590por Prasoon, Pankaj, Hirose, Yuki, Sakata, Jun, Yuza, Kizuki, Moro, Kazuki, Toge, Koji, Miura, Kohei, Nagahashi, Masayuki, Kobayashi, Takashi, Nihei, Kouei, Nakamura, Atsuo, Wakai, Toshifumi“…CASE PRESENTATION: An 81-year-old female presented with abdominal pain. Her medical history included a laparoscopic cholecystectomy for cholecystolithiasis two years prior. …”
Publicado 2019
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55591“…BACKGROUND: Domestic violence (DV) during pregnancy is recognized as a global health problem associated with serious health consequences for both the mother and her baby. Several interventions aimed at addressing DV around the time of pregnancy have been developed in the last decade, but they are primarily from developed countries. …”
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55592“…To improve the health outcomes of hypertensive disorders of pregnancy, it is recommended to improve utilization of maternal health service; early detection and early referral of pregnant women with hypertensive disorder; advocating policies and strategies that improves the quality of health care that a pregnant woman and her newborn receive.…”
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55593por Tahmasebi, Sedigheh, Tajali, Mahsa, Akrami, Majid, Arasteh, Peyman, Zangouri, Vahid, Nobandegani, Aida Salehi, Hosseini, Seyed Morteza, Safari, Afsoon, Talei, Abdolrasoul“…ER positive (62.4%, 73.4%, and 77.1%, respectively; p < 0.001) and PR positive individuals (59.5%, 64.3%, 72.6%, respectively; p < 0.001) showed an increasing trend. HER2 positive expression rates increased from 1993–2005 to 2005–2011 (24.5% and 31.5%, respectively) and decreased onto 2012–2017 (31.5% and 26.8%, respectively, p < 0.001). …”
Publicado 2019
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55594por Berta, Marta, Lindgren, Helena, Christensson, Kyllike, Mekonnen, Sollomon, Adefris, Mulat“…Even though the reduction in duration varies across studies with considerable heterogeneity, laboring women should be encouraged to choose her comfortable birth position. Researchers who aim to compare different birthing positions should consider study designs which enable women to choose birthing position. …”
Publicado 2019
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55595“…A current trend in survey research is to combine Web-based surveys with other survey modes by offering the participant the possibility of choosing his/her preferred response method (i.e. mixed-mode approach). …”
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55596“…CONCLUSION: Good communication between mothers and HWs is critical for building mothers’ confidence, promoting bonding and participation of mothers in the care of their baby and may have long term benefits for the health and well-being of the mother and her baby.…”
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55597por Yonesaka, Kimio, Iwama, Eiji, Hayashi, Hidetoshi, Suzuki, Shinichiro, Kato, Ryoji, Watanabe, Satomi, Takahama, Takayuki, Tanizaki, Junko, Tanaka, Kaoru, Takeda, Masayuki, Sakai, Kazuko, Azuma, Koichi, Chiba, Yasutaka, Atagi, Shinji, Nishio, Kazuto, Okamoto, Isamu, Nakagawa, Kazuhiko“…Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) are standard therapy for EGFR-mutant non-small cell lung cancer (NSCLC). Preclinically, HER3 ligand heregulin induces resistance to EGFR-TKIs, whereas the pan-human EGFR family inhibitor afatinib remains effective. …”
Publicado 2019
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55598“…BACKGROUND: Street child is any child whose age is less than 18 years for whom the street has become his or her habitual abode and/or source of livelihood, is inadequately protected, supervised or directed by responsible adults. …”
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55599por Murat El Houdigui, Sophia, Adam-Guillermin, Christelle, Loro, Giovanna, Arcanjo, Caroline, Frelon, Sandrine, Floriani, Magali, Dubourg, Nicolas, Baudelet, Emilie, Audebert, Stéphane, Camoin, Luc, Armant, Olivier“…Whole-mount RNA in situ hybridization confirmed the impaired expression of the transcription factors her4.4 in the central nervous system and myogenin in the developing muscles of exposed embryos. …”
Publicado 2019
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55600por Kizilboga, Tugba, Baskale, Emine Arzu, Yildiz, Jale, Akcay, Izzet Mehmet, Zemheri, Ebru, Can, Nisan Denizce, Ozden, Can, Demir, Salih, Ezberci, Fikret, Dinler-Doganay, Gizem“…RESULTS: We observed that Bag-1 is overexpressed in breast tumors in all molecular subtypes, i.e., regardless of their ER, PR and Her2 expression profile. Ectopic expression of Bag-1 in breast cancer cell lines results in the activation of B-Raf, C-Raf and Akt kinases, which are also upregulated in breast tumors. …”
Publicado 2019
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