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55601“…In fact, the “single gene report” only contains unscaled scores of the ER, PR, and Her2 genes without any internationally accepted unit used to describe a transcript quantity. …”
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55602por Saunders, Carina Madelen, Rehbinder, Eva Maria, Carlsen, Karin C. Lødrup, Gudbrandsgard, Malén, Carlsen, Kai-Håkon, Haugen, Guttorm, Hedlin, Gunilla, Jonassen, Christine Monceyron, Sjøborg, Katrine Dønvold, Landrø, Linn, Nordlund, Björn, Rudi, Knut, O.Skjerven, Håvard, Söderhäll, Cilla, Staff, Anne Cathrine, Vettukattil, Riyas, Carlsen, Monica Hauger“…BACKGROUND: A woman’s food intake during pregnancy has important implications not only for herself but also for the future health and well-being of her child. Suboptimal dietary quality has been consistently reported in many high-income countries, reflecting poor adherence to dietary guidelines. …”
Publicado 2019
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55603por Giro-Perafita, A., Luo, L., Khodadadi-Jamayran, A., Thompson, M., Akgol Oksuz, B., Tsirigos, A., Dynlacht, B. D., Sánchez, I., Esteva, F. J.“…Basal-like breast cancers are generally poorly differentiated tumors, are enriched in embryonic stem cell signatures, lack expression of estrogen receptor, progesterone receptor, and HER2 (triple-negative breast cancer), and show activation of proliferation-associated factors. …”
Publicado 2020
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55604por Wan, Xing, Song, Yongxi, Fang, Honghong, Xu, Ling, Che, Xiaofang, Wang, Shuo, Zhang, Xiaomeng, Zhang, Lingyun, Li, Ce, Fan, Yibo, Hou, Kezuo, Li, Zhi, Wang, Xueqing, Liu, Yunpeng, Qu, Xiujuan“…RANKL contributed to the activation of human epidermal growth factor receptor (HER) family pathways. The lipid raft core protein, caveolin 1 (Cav-1), interacted with both RANK and human epidermal growth factor receptor-1(EGFR). …”
Publicado 2020
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55605“…Louise Davies, Associate Professor of Surgery—Otolaryngology—Head and Neck Surgery, Geisel School of Medicine at Dartmouth, Hanover, NH, for her valuable comments on the creation of this video. …”
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55606por de Souza, Lucas André Schuster, Cancian, Ana Carolina Maciel, de Castro, Thiago Gomes, da Silva Oliveira, Margareth“…BACKGROUND: Dialectical behavior therapy conceptualizes problematic behaviors as attempts to regulate emotions that occur when the individual lacks effective skills with which to manage his or her emotions and cope with distress. Problematic eating behaviors, e.g., binge and emotional eating, may serve to alleviate aversive emotional states, being highly associated with overweight and obesity. …”
Publicado 2019
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55607por Furukawa, Kenichiro, Niihara, Masahiro, Kawata, Takuya, Mayanagi, Shuhei, Tsubosa, Yasuhiro“…The tumor cells of the adenocarcinoma component had periodic acid-Schiff (PAS)-positive globules and were positive for sal-like protein 4 (SALL 4) and negative for α-fetoprotein (AFP) or human epidermal growth factor receptor type 2 (HER2). The type 1 tumors consisted of the adenocarcinoma-like type 2 tumor and spindle cells (sarcomatous component). …”
Publicado 2020
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55608por Segar, Jennifer M., Reed, Darien, Stopeck, Alison, Livingston, Robert B., Chalasani, Pavani“…Median age was 54 (range, 36‐84), with the majority (64%) having hormone receptor positive (HR+) human epidermal growth factor receptor 2 negative (HER2 neg) MBC. Median number of prior therapies was five (range, 3–14). …”
Publicado 2019
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55609“…Health workers should counsel every woman on birth preparedness and complication readiness components during her first antenatal care visit and subsequent visits.…”
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55610por Ni-jia-ti, Ma-yi-di-li, Ai-hai-ti, Di-li-a-re-mu, Huo-jia, Ai-si-ka-er-jiang, Wu-mai-er, Pa-li-dan-mu, A-bu-li-zi, A-bu-du-ke-you-mu-jiang, Shi, Yu, Rou-zi, Nu-er-a-mi-na, Su, Wen-jing, Dai, Guo-zhao, Da-mo-la, Mai-he-mi-ti-jiang“…RESULTS: Tumor margins, lobulation sign, diffusion-weighted imaging appearance, MRI-reported axillary lymph node metastasis, time to signal intensity curve pattern, and HER-2 were selected as predictors for LVI in the point-based scoring system. …”
Publicado 2020
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55611por Han, Mingli, Gu, Yuanting, Lu, Pengwei, Li, Jingyi, Cao, Hui, Li, Xiangke, Qian, Xueke, Yu, Chao, Yang, Yunqing, Yang, Xue, Han, Na, Dou, Dongwei, Hu, Jianguo, Dong, Huaying“…BACKGROUND: Although trastuzumab provides significant clinical benefit for HER2-positive breast cancers, responses are limited by the emergence of resistance. …”
Publicado 2020
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55612por Hua, Xin, Long, Zhi-Qing, Huang, Xin, Deng, Jia-Peng, He, Zhen-Yu, Guo, Ling, Zhang, Wen-Wen, Lin, Huan-Xin“…Results: Subgroup analyses of patients with low PNI value (≤52.0) and high PNI value (>52.0) showed that a high PNI was significantly associated with HER2 status, the neutrophil–lymphocyte ratio (NLR), the monocyte–lymphocyte ratio (MLR), and KI 67 status. …”
Publicado 2020
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55613“…BACKGROUND: In order improve the quality of birth care and women satisfaction with birthing process it is recommended that every woman should be offered the option to experience labour and childbirth with a companion of her choice. Involving husbands who are decision makers in the household may a play role in reducing maternal mortality which is unacceptably high despite the targeted goal to reduce this mortality up to three quarters as targeted in the MDGs by 2015. …”
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55614“…From them, less than half, 47 (43.9%) said that an apparently healthy woman should undergo the test at least three times in her life. This means in addition to the lack of information about the test, majority of those who had heard about it didn’t know how many times they should have the test in their life. …”
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55615“…Dual contraceptive use is one of the best actions to prevent mother’s human immune deficiency virus transmission to her child and partner. This study aimed at assessing the prevalence and factors associated with dual contraceptive use among sexually active women on antiretroviral therapy in Gondar City, northwest, Ethiopia. …”
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55616“…For IPV, exposure to conflict increased the odds a respondent would tell someone about her experience (aOR 1.7; 95%CI 1.2–2.5; p < .01), but was not associated with seeking support services. …”
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55617por Harrington, Brittney S., He, Yaowu, Khan, Tashbib, Puttick, Simon, Conroy, Paul J., Kryza, Thomas, Cuda, Tahleesa, Sokolowski, Kamil A, Tse, Brian WC, Robbins, Katherine K., Arachchige, Buddhika J., Stehbens, Samantha J., Pollock, Pamela M., Reed, Sarah, Weroha, S. John, Haluska, Paul, Salomon, Carlos, Lourie, Rohan, Perrin, Lewis C., Law, Ruby H. P., Whisstock, James C., Hooper, John D“…CUB-domain containing protein 1 (CDCP1) is a cancer associated cell surface protein that amplifies pro-tumorigenic signalling by other receptors including EGFR and HER2. Its potential as a cancer target is supported by studies showing that anti-CDCP1 antibodies inhibit cell migration and survival in vitro, and tumor growth and metastasis in vivo. …”
Publicado 2020
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55618“…Recently, the concept of temporary crating has been introduced to achieve a compromise between the needs of the sow and her piglets. According to this concept, sows could be kept out of the crate at the time of prenatal nest-building behaviour and after the critical period of piglets’ life. …”
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55619por Shao, Wanting, Kuhn, Christina, Mayr, Doris, Ditsch, Nina, Kailuwait, Magdalena, Wolf, Verena, Harbeck, Nadia, Mahner, Sven, Jeschke, Udo, Cavaillès, Vincent, Sixou, Sophie“…Cytoplasmic PPARγ was inversely correlated with nuclear PPARγ and ER expression, but positively with Cox-1, Cox-2, and other high-risk markers of BC, e.g. HER2, CD133, and N-cadherin. Overall survival analysis demonstrated that cytoplasmic PPARγ had a strong correlation with poor survival in the whole cohort, and even stronger in the subgroup of patients with no Cox-1 expression where cytoplasmic PPARγ expression appeared as an independent marker of poor prognosis. …”
Publicado 2020
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55620por Bravaccini, Sara, Bronte, Giuseppe, Scarpi, Emanuela, Ravaioli, Sara, Maltoni, Roberta, Mangia, Anita, Tumedei, Maria Maddalena, Puccetti, Maurizio, Serra, Patrizia, Gianni, Lorenzo, Amaducci, Laura, Biglia, Nicoletta, Bounous, Valentina, Paradiso, Angelo Virgilio, Silvestrini, Rosella, Amadori, Dino, Rocca, Andrea“…RESULTS: Considering both cut-off values of 10% and 20%, PgR expression was significantly associated with age, menopausal status, and ER expression; HER2 status was associated with PgR status only at a cutoff value of 20% PgR. …”
Publicado 2020
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