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55781por Halbony, Hala, Salman, Khadija, Alqassieh, Ahmad, Albrezat, Mutaz, Hamdan, Ahmad, Abualhaija’a, Ali, Alsaeidi, Omar, Masad Melhem, Jamal, Sagiroglu, Julide, Alimoglu, Orhan“…According to the results of pathological examinations, 72.6% (85 patients) of the cases were estrogen receptor positive, 61.2% (71 patients) were progesterone receptor positive while 24.8% (27 patients) were HER positive. Modified radical mastectomy (MRM) was performed in 52 (43.3%) patients and wide local excision (WLE) was preferred in 46 (38.3%) cases. …”
Publicado 2020
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55782por Jackson, Evangeline R, Duchatel, Ryan J, Mannan, Abdul, Hulleman, Esther, Carcaboso, Angel M, Monje, Michelle, McCowage, Geoff B, Alvaro, Frank, Dun, Matthew D“…This combination was used to treat a 3-year-old DIPG patient, commencing 14 weeks post disease progression, completing 40 weeks of therapy prior to her passing, December 2019. These studies highlight the potential of combined administration of two safe, BBB penetrant, oral targeted therapies and supports testing under clinical trial conditions.…”
Publicado 2020
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55783por Hu, Xuyun, Wu, Di, Li, Yuchuan, Wei, Liya, Li, Xiaoqiao, Qin, Miao, Li, Hongdou, Li, Mengting, Chen, Shaoke, Gong, Chunxiu, Shen, Yiping“…RESULTS: A novel loss of function NSD2 variant, c.1577dupG (p.Asn527Lysfs*14), was identified in a Chinese family in the proband and her father both affected with intellectual disability. …”
Publicado 2020
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55784por Pan, Yuejuan, Cui, Zhuan, Wang, Song, Zheng, Danxia, Deng, Zhenling, Tian, Xinyu, Guo, Hongxia, Bao, Wenhan, Zhou, Sijia, Wang, Yue“…A computed tomography (CT) scan revealed a tissue mass in the thymus area and enlarged multiple lymph nodes. Her symptoms did not improve after resection of the thymus mass. …”
Publicado 2020
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55785por Kim, Ju-Yeon, Jung, Eun Jung, Kim, Jae-Myung, Lee, Han Shin, Kwag, Seung-Jin, Park, Ji-Ho, Park, Taejin, Jeong, Sang-Ho, Jeong, Chi-Young, Ju, Young-Tae“…In univariate analysis, metastasis-free survival, patient age at diagnosis, tumor size, axillary lymph node metastasis, HER-2 status, initial NLR and PLR, and 2nd NLR and PLR were found to be significantly associated with delayed metastasis. …”
Publicado 2020
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55786por Maseda, Rocío, Martínez-Santamaría, Lucía, Sacedón, Rosa, Butta, Nora, de Arriba, María del Carmen, García-Barcenilla, Sara, García, Marta, Illera, Nuria, Pérez-Conde, Isabel, Carretero, Marta, Jiménez, Eva, Melen, Gustavo, Borobia, Alberto M., Jiménez-Yuste, Víctor, Vicente, Ángeles, del Río, Marcela, de Lucas, Raúl, Escámez, María José“…The patient presented with long-lasting refractory and painful oral ulcers distressing her quality of life. Histamine receptor antagonists, opioid analgesics, proton-pump inhibitors, and low-dose tricyclic antidepressants barely improved gastric symptoms, pain, and pruritus. …”
Publicado 2020
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55787“…C670T, p.R224W), but no mutation was found in the healthy skin and peripheral blood sample of the index patient, or in the blood samples of her parents and sibling. PCR-mediated Sanger sequencing of DNA derived from lesional skin sample of the index patient verified KRAS mutation, but not PRKRIR (c.A1674T, p.R558S) and RRP7A (c. …”
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55788por Ota, Yoshiaki, Ota, Kuniaki, Takahashi, Toshifumi, Suzki, Soichiro, Sano, Rikiya, Ota, Ikuko, Moriya, Takuya, Shiota, Mitsuru“…CASE PRESENTATION: Six years ago, the patient underwent laparoscopic bilateral salpingo-oophorectomy for her right ovarian tumor with atypical proliferative (borderline) endometrioid tumor accompanied by ovarian endometrioma. …”
Publicado 2020
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55789por Zhang, Hui, Chen, Can, Tang, An, Wu, Bing, Liu, Leijie, Wu, Mingyu, Wang, Hongling“…Then, the second case played an important role in the spread of virus due to her occupation. The molecular phylogenetic analysis could help to track the origin of the virus. …”
Publicado 2020
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55790por Jin, Young-Hee, Min, Jung Sun, Jeon, Sangeun, Lee, Jihye, Kim, Seungtaek, Park, Tamina, Park, Daeui, Jang, Min Seong, Park, Chul Min, Song, Jong Hwan, Kim, Hyoung Rae, Kwon, Sunoh“…Lycorine is a phenanthridine Amaryllidaceae alkaloid isolated from the bulbs of Lycoris radiata (L'Hér.) Herb. and has various pharmacological bioactivities including antiviral function. …”
Publicado 2021
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55791“…Getting to know a person and his/her family will also facilitate the possibility to ensure a more familiar and homely context. …”
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55792por Gubarkova, Ekaterina V., Kiseleva, Elena B., Sirotkina, Marina A., Vorontsov, Dmitry A., Achkasova, Ksenia A., Kuznetsov, Sergey S., Yashin, Konstantin S., Matveyev, Aleksander L., Sovetsky, Aleksander A., Matveev, Lev A., Plekhanov, Anton A., Vorontsov, Alexey Y., Zaitsev, Vladimir Y., Gladkova, Natalia D.“…The study used 70 excised breast cancer specimens with different morphological structure and molecular status (Luminal A, Luminal B, Her2/Neo+, non-luminal and triple-negative cancer). …”
Publicado 2020
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55793por Baumann, Sophie, Gaucher, Laurent, Bourgueil, Yann, Saint-Lary, Olivier, Gautier, Sylvain, Rousseau, Anne“…KEY CONCLUSIONS: Without guidelines, each midwife had to decide individually if and how to adapt her practice. Postpartum pelvic floor rehabilitation and birth preparation have been strongly affected. …”
Publicado 2021
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55794por Guo, Zhanfang, Primeau, Tina, Luo, Jingqin, Zhang, Cynthia, Sun, Hua, Hoog, Jeremy, Gao, Feng, Huang, Shixia, Edwards, Dean P., Davies, Sherri R., Aft, Rebecca, Ding, Li, Ellis, Matthew J., Li, Shunqiang, Ma, Cynthia X.“…Several biomarkers showed significant association with resistance, including elevated baseline levels of growth factor receptors (EGFR, pHER3 Y1197), PI3Kp85 regulatory subunit, anti-apoptotic protein BclXL, EMT (Vimentin, MMP9, IntegrinaV), NFKB pathway (IkappaB, RANKL), and intracellular signaling molecules including Caveolin, CBP, and KLF4, as well as treatment-induced increases in the levels of phosphorylated forms of Aurora kinases. …”
Publicado 2020
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55795“…CASE SUMMARY: An 84-year-old Chinese woman was admitted with gradual abdominal distension. Her symptoms started 1 year ago, and she had poor appetite and a weight loss of 5 kg within the past 2 wk. …”
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55796por Corpuz, Marilou, Jain, Ruchika, Weston, Gregory, Nori, Priya, Nori, Priya, Boland-Reardon, Carmel, Bernard, Evan, Graham, Esther, Madaline, Theresa“…Hosp B: On 4/1, one of the patients in a 22 bed Psych unit, admitted since 3/10/20, developed fever, cough and tested positive for COVID-19 PCR. Two of her close contacts tested positive for SARS-COV-2 PCR. …”
Publicado 2020
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55797“…Educational effectiveness was assessed with a repeated-pairs pre-/post-assessment study design; each individual served as his/her own control. A chi-square test assessed changes pre- to post-assessment. …”
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55798“…An adolescent female presented with an ascending pelvic infection progressing to purulent polymicrobial peritonitis (see table) requiring surgical debridement and cefipime, metronidazole and micafungin therapy; her course was complicated by progressive peritonitis/abscesses. …”
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55799“…Educational effectiveness was assessed with a repeated-pairs pre-/post-assessment study design; each individual served as his/her own control. A chi-square test assessed changes pre- to post-assessment. …”
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55800“…She is living with HIV/AIDS with virologic control and CD4 count of 470 treated with dose adjusted lamivudine, tenofovir alafenamide, and dolutegravir in the setting of ESRD on HD, chronic hepatitis B, and group I pulmonary hypertension. Her course was complicated by development of multifocal pneumonia with hypoxemic respiratory failure requiring high-flow nasal cannula. …”
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