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55981por Liu, Zhiwan, Zhang, Wenjun, Zhang, Boyu, Ma, Linhao, Zhou, Feng, Hu, Zheyuan, Jie, Xiang, Gao, Hong, Zhu, Xiaohai“…Authors used a series of debridement and reconstructive surgery including vacuum sealing drainage (VSD) treatment, artificial dermis grafts,split-thickness skin grafts, amputation surgeries when her vital signs were stable. The patient experienced desquamation of the hand on the 26th day. …”
Publicado 2021
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55982“…One of these rare cases was investigated here using samples from a mare and her foal. Intoxication by hypoglycin A and methylenecyclopropylglycine is also of interest to human pathology, because these toxins have caused fatal poisonings after consumption of certain fruits many times, especially in children. …”
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55983por Ali, Amjad, Shafarin, Jasmin, Unnikannan, Hema, Al-Jabi, Nour, Jabal, Rola Abu, Bajbouj, Khuloud, Muhammad, Jibran Sualeh, Hamad, Mawieh“…However, combined inhibition of BRD4-RAC1 signaling pathways in different molecular subtypes of breast cancer including luminal-A, HER-2 positive and triple-negative breast (TNBC) largely remains unknown. …”
Publicado 2021
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55984por Lemoine, Pauline, Bruand, Marie, Kammerer, Emmanuel, Bogart, Emilie, Comte, Pauline, Royer, Philippe, Thariat, Juliette, Pasquier, David“…The primary tumor expressed estrogen receptors in 33 patients (84.6%); the status was HER2+++ in 7 patients (17.9%). The median dose was 40 Gy (min-max: 15-54) prescribed at 80% isodose, the median number of sessions was three (min-max: 3-10). …”
Publicado 2021
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55985por Duchnowska, Renata, Saad, Everardo D., Banaszek, Małgorzata, Pawłowska, Ewa, Liberek, Hanna, Cichowska-Cwalińska, Natalia, Jassem, Jacek“…There was a significant increase over time in the percentages of trials allowing patients with BM (p < 0.001), and these trials were more frequently dedicated to HER2-positive or triple-negative disease (p = 0.001). …”
Publicado 2021
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55986por Erber, Ramona, Kailayangiri, Sareetha, Huebner, Hanna, Ruebner, Matthias, Hartmann, Arndt, Häberle, Lothar, Meyer, Julia, Völkl, Simon, Mackensen, Andreas, Landgraf, Laura, Geppert, Carol I., Schulz-Wendtland, Rüdiger, Beckmann, Matthias W., Fasching, Peter A., Farwick, Nicole, Rossig, Claudia, Gass, Paul“…The proportion of GD2-expressing tumors were significantly lower in HER2-positive breast cancer in comparison with luminal tumors on IF staining (but not IHC). …”
Publicado 2021
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55987por Amirfallah, Arsalan, Knutsdottir, Hildur, Arason, Adalgeir, Hilmarsdottir, Bylgja, Johannsson, Oskar T., Agnarsson, Bjarni A., Barkardottir, Rosa B., Reynisdottir, Inga“…Specifically, in the largest validation cohort, METABRIC (n = 1174), high miR-21-3p levels associated with large tumors, a high grade, lymph node and HER2 positivity, and shorter breast-cancer-specific survival (HR = 1.38, CI 1.13–1.68). …”
Publicado 2021
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55988por Bulzu, Paul-Adrian, Kavagutti, Vinicius Silva, Chiriac, Maria-Cecilia, Vavourakis, Charlotte D., Inoue, Keiichi, Kandori, Hideki, Andrei, Adrian-Stefan, Ghai, Rohit“…In addition, we also describe two novel putative signal-transducing domains fused to some HeRs. We posit that HeRs likely function as generalized light-dependent switches involved in the mitigation of light-induced oxidative stress and metabolic circuitry regulation. …”
Publicado 2021
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55989por Ketema, Worku, Taye, Kefyalew, Shibeshi, Mulugeta Sitot, Tagesse, Negash, Hirigo, Agete Tadewos, Woubishet, Kindie, Gutema, Selamawit, Eifa, Aberash, Toma, Alemayehu“…CASE SUMMARY: This is a case of a 40-year-old female known HIV/AIDS patient who has been on ART for the last 14 years with good adherence and regular follow-up, and who is now on 3rd line ART medication with TLD (tenofovir/lamivudine/dolutegravir)+DRV/r (in her 11th month) after being diagnosed with second-line treatment failure. …”
Publicado 2021
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55990por González-Espinoza, Alfredo, Zamora-Fuentes, Jose, Hernández-Lemus, Enrique, Espinal-Enríquez, Jesús“…In this work, we developed a hybrid method to analyze whole-chromosome Pearson correlation matrices for the four BrCa subtypes (Luminal A, Luminal B, HER2+ and Basal), as well as adjacent normal breast tissue derived matrices. …”
Publicado 2021
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55991por Liu, Cheng, Yang, Ziyi, Liu, Mingyu, Wang, Xiangwei, Song, Shaoli, Xu, Xiaoping, Yang, Zhongyi“…Human breast cancer MCF-7 (ER+/HER2−) cells were used for in vitro cell uptake tests. …”
Publicado 2021
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55992“…The patient’s serum concentration of azelnidipine at the time of her visit to our center was 63.4 ng/mL, higher than the normal acceptable level. …”
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55993por Labiris, Georgios, Panagiotopoulou, Eirini-Kanella, Taliantzis, Sergios, Perente, Asli, Delibasis, Konstantinos, Doulos, Lambros T“…Following dark adaptation, illuminance was gradually raised from 20 lx until illuminance level that the patient reached his/her optimal UDVA. This measured illuminance at this point was defined as the minimum required illuminance level (MRIL). …”
Publicado 2021
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55994por Ogunsiakan, Tosin, Fajgenbaum, Kristen D, Phadke, Gautam, Montgomery, Thomas, Gajurel, Kiran“…RESULTS: Case 1: A 31-year female kidney transplant recipient presented with a thyroglossal duct cyst, as well as swelling of her right metacarpophalangeal joint and left 3rd finger. …”
Publicado 2021
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55995“…The commonest symptom of inattention was “failing to give close attention in school” (73%) whereas the commonest symptom of hyperactivity was “trouble waiting for his/her turn” (66%). Seven participants satisfied complete criteria for ADHD. …”
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55996por Sharifinejad, Niusha, Sadri, Homa, Kalantari, Arash, Delavari, Samaneh, Noohi, Amirhosein, Aminpour, Yasaman, Sabzevari, Araz, Azizi, Gholamreza“…CASE PRESENTATION: We reported a novel case of a 27 months old girl presenting with recurrent pneumonia and a history of skeletal tuberculosis at the age of 19-month-old. Her immunological workup revealed persistent lymphopenia and low CD4 + T cell count along with elevated levels of CD19 +, CD20 +, CD16 +, and CD56 + cells. …”
Publicado 2021
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55997por Thulin, Anna, Andersson, Carola, Werner Rönnerman, Elisabeth, De Lara, Shahin, Chamalidou, Chaido, Schoenfeld, Arnd, Kovács, Anikó, Fagman, Henrik, Enlund, Fredrik, Linderholm, Barbro K.“…Secondary aims were to determine mutations in each subgroup (Luminal A-/B-like, HER2+ and TNBC) of BCBM, and to determine survival according to specific mutations. …”
Publicado 2021
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55998por Hsieh, Tsung-Han, Liang, Muh-Lii, Zheng, Jia-Huei, Lin, Yu-Chen, Yang, Yu-Chen, Vo, Thanh-Hoa, Liou, Jing-Ping, Yen, Yun, Chen, Chun-Han“…CDK4/6 inhibitors are newly FDA-approved agents to treat HR-positive, HER2-negative advanced, and metastatic breast cancers, and preclinical results showed that CDK4/6 inhibitors significantly reduced cell proliferation and tumor growth. …”
Publicado 2021
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55999por Watanabe, Yuko, Igaki, Hiroshi, Arakawa, Ayumu, Yanagisawa, Shunsuke, Takahashi, Masamichi, Ohno, Makoto, Miyakita, Yasuji, Satomi, Kaishi, Yoshida, Akihiko, Isohashi, Kayako, Ono, Koji, Miyatake, Shin-Ichi, Chen, Yi-Wei, Ogawa, Chitose, Narita, Yoshitaka“…After she was diagnosed with MPNST in the pathology consultation at our hospital, she was irradiated with heavy ion beam 70.8Gy(RBE)/16fr and received additional chemotherapies at our department, but her tumor was refractory. Although BNCT for MPNST is not covered by health insurance in Japan, she wanted to try to be treated for BNCT. …”
Publicado 2021
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56000por Morikawa, Satoru, Watanabe, Kazuya, Usuda, Satoshi, Miyashita, Yoko, Nakagawa, Taneaki“…She had developed pancytopenia at age 11 years and was later diagnosed with aplastic anemia, making her susceptible to infection due to leukopenia. …”
Publicado 2021
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