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56321por Caballo, Marco, Sanderink, Wendelien B. G., Han, Luyi, Gao, Yuan, Athanasiou, Alexandra, Mann, Ritse M.“…The ML models achieved significant AUC of 0.707 (all cancers, n = 251, 59 pCR), 0.824 (luminal A, n = 107, 14 pCR), 0.823 (luminal B, n = 47, 15 pCR), 0.844 (HER2 enriched, n = 25, 11 pCR), 0.803 (triple negative, n = 72, 19 pCR). …”
Publicado 2022
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56322por Mailliez, Audrey, D'Hondt, Veronique, Lusque, Amelie, Caron, Olivier, Cabel, Luc, Goncalves, Anthony, Debled, Marc, Gladieff, Laurence, Ferrero, Jean‐Marc, Petit, Thierry, Mouret‐Reynier, Marie Ange, Eymard, Jean‐Christophe, Levy, Christelle, Uwer, Lionel, Leheurteur, Marianne, Desmoulins, Isabelle, Bachelot, Thomas, Frenel, Jean‐Sebastien, de la Motte Rouge, Thibault, Simon, Gaëtane, Jacot, William, Delaloge, Suzette“…In contrast, in patients with HR+/HER2 negative cancers, PFS1 appeared significantly and OS non significantly lower for gBRCAm carriers (PFS1: HR vs WT = 1.23; 95%CI: 1.03‐1.46; P = .024; OS:HR = 1.22, 95% CI: 0.97‐1.52, P = .089). …”
Publicado 2022
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56323por Cecere, Francesco, Pignata, Laura, Hay Mele, Bruno, Saadat, Abu, D’Angelo, Emilia, Palumbo, Orazio, Palumbo, Pietro, Carella, Massimo, Scarano, Gioacchino, Rossi, Giovanni Battista, Angelini, Claudia, Sparago, Angela, Cerrato, Flavia, Riccio, Andrea“…To look for a possible molecular link between BWSp and EO-CRC, we analysed her whole-genome genetic and epigenetic profiles in blood, and peri-neoplastic and neoplastic colon tissues. …”
Publicado 2023
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56324por Rahman, Mizanur, Jamil, Kanta, Nahar, Quamrun, Chakraborty, Nitai, Haider, M. Moinuddin, Khan, Shusmita“…IPPV is defined as the respondent having physical violence perpetrated by her husband at least once in the last 12 months. …”
Publicado 2023
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56325por Utsu, Yoshikazu, Kawakami, Makio, Arai, Hironori, Hisamatsu, Haruka, Yano, Yudai, Terada, Jiro“…Two-dimensional transthoracic echocardiography demonstrated right atrial and ventricular dilatation, tricuspid regurgitation, and a high trans-tricuspid pressure gradient of 65 mmHg. Despite her percutaneous oxygen saturation being 96% on room air at the time of admission, it worsened rapidly; the patient requiring 8 L/min of oxygen within 4 h. …”
Publicado 2023
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56326por Lin, Daniel, Nguyen, Hiep, Shah, Ruchit, Qiao, Yao, Hartman, John, Sugarman, Ryan“…BACKGROUND: The phase 3 CheckMate 649 established superior overall survival of nivolumab in combination with chemotherapy (NIVO + chemo) compared with chemotherapy (chemo) alone as a first-line treatment for patients with Her2-negative advanced gastric cancer, gastroesophageal junction cancer, and esophageal adenocarcinoma (GC/GEJC/EAC). …”
Publicado 2023
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56327“…Participants enrolled at any point during their pregnancy and surveys were delivered weekly until the participant indicated that she had delivered her baby; a postpartum survey followed four weeks after delivery. …”
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56328por Ring, Alistair, Karuturi, Meghan, Smyth, Emily Nash, Lokhandwala, Tasneem, Sheffield, Kristin M., Willey, Joanne, Lunacsek, Orsolya, Sapunar, Francisco, Cui, Zhanglin Lin, Coutinho, Anna, Rybowski, Sarah“…METHODS: This analysis was a part of a broader, retrospective study that analyzed electronic medical records and charts of 448 men and women with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2−) MBC who initiated an abemaciclib-containing regimen from January 2017 through September 2019. …”
Publicado 2023
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56329Overlap syndrome of primary biliary cholangitis and primary sclerosing cholangitis: two case reportspor Yacoub, Haythem, Ben Azouz, Sarra, Hassine, Hajer, Debbabi, Habiba, Cherif, Dhouha, Ghayeb, Feriel, Boukriba, Seif, Kchir, Héla, Maamouri, Nadia“…The second case is a middle-aged woman, suffering from primary biliary cholangitis and who was treated with ursodeoxycholic acid. At her 12 month follow-up appointment, she presented with a partial clinical and biochemical response. …”
Publicado 2023
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56330por Wen, Pu-yuan, Chen, Xian-wen, Zhang, Min, Chu, Wen-zheng, Wu, Hong-liang, Ren, Chao“…The patient underwent emergency percutaneous intervention of the posterior collateral artery of the right coronary artery. Soon after, her condition worsened resulting in limb weakness and numbness. …”
Publicado 2023
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56331por Song, Ying, Wang, Jinlu, Wang, Xiuli, Li, Rui, Niu, Xingjian, Yang, Yue, Yang, Xudong, Yin, Lei, Wang, Yiran, Zhang, Han, Shui, Ruixue, Zhang, Cuiying, An, Jing“…OS risk of BC survivors with second primary cancers was significantly associated with age, menopause status, family history, tumor size, lymph node metastasis, and human epidermal growth factor receptor 2 (HER2) status. CONCLUSIONS: The identification of double primary cancers in earlier stages could play a critical role in guidance and lead to better outcomes. …”
Publicado 2023
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56332por Iwata, Hiroji, Yamamoto, Yutaka, Sakai, Takehiko, Hasegawa, Yoshie, Nakamura, Rikiya, Akabane, Hiromitsu, Ohtani, Shoichiro, Kashiwaba, Masahiro, Taira, Naruto, Toyama, Tatsuya, Fujisawa, Tomomi, Masuda, Norikazu, Shibahara, Yukiko, Sasano, Hironobu, Yamaguchi, Takuhiro“…This phase III trial evaluated the prognosis of EBC patients treated with/without chemotherapy (CT) following NET. METHODS: ER+/HER2−, T1c-2, and clinically node-negative EBC patients were enrolled in 2008–2013 and treated with endocrine therapy (ET) in weeks 24–28. …”
Publicado 2023
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56333por Cheng, Robert Y. S., Ridnour, Lisa A., Wink, Adelaide L., Gonzalez, Ana L., Femino, Elise L., Rittscher, Helene, Somasundaram, Veena, Heinz, William F., Coutinho, Leandro, Rangel, M. Cristina, Edmondson, Elijah F., Butcher, Donna, Kinders, Robert J., Li, Xiaoxian, Wong, Stephen T. C., McVicar, Daniel W., Anderson, Stephen K., Pore, Milind, Hewitt, Stephen M., Billiar, Timothy R., Glynn, Sharon A., Chang, Jenny C., Lockett, Stephen J., Ambs, Stefan, Wink, David A.“…To explore this conundrum, tumor NOS2, COX2, and CD8(+) T cells were spatially analyzed in aggressive ER–, TNBC, and HER2 + breast tumors. High expression and clustering of NOS2-expressing tumor cells occurred at the tumor/stroma interface in the presence of stroma-restricted CD8(+) T cells. …”
Publicado 2023
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56334“…Proper oral health is crucial both for mother and her babies and is related with mothers’ awareness of this connection. …”
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56335por Lakhani, Kinjal S, Joshi, Samir, Pawar, Sudhir, Lohokare, Aishwarya U, Rathod, Priyanka B“…In group A, the patient was asked to put his or her hand of the same side as the palatal injection in an ice-cold bath till the time patient could tolerate it; immediately after the patient removed his hand, the greater palatine nerve block was given, and the patient was assessed for the injection pain. …”
Publicado 2023
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56336por Abdulraheem, Ahmad M., Naji, Duha, Al Heyasat, Ammar N., Alhasan, Mohammad, Almasri, Nidal M., Odeh, Raghad“…She presented in September of 2022 with enlarging scalp nodules, which started developing 2 months prior to her presentation. Physical examination revealed firm, non-tender, and immobile skin lesions. …”
Publicado 2023
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56337por Takano, Elena A., Younes, Melissa M., Meehan, Katie, Spalding, Lisa, Yan, Max, Allan, Prue, Fox, Stephen B., Redfern, Andy, Clouston, David, Giles, Graham G., Christie, Elizabeth L., Anderson, Robin L., Zethoven, Magnus, Phillips, Kelly-Anne, Gorringe, Kylie, Britt, Kara L.“…BACKGROUND: Triple negative BCa (TNBC) is defined by a lack of expression of estrogen (ERα), progesterone (PgR) receptors and human epidermal growth factor receptor 2 (HER2) as assessed by protein expression and/or gene amplification. …”
Publicado 2023
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56338“…The most common DDR gene with suppressed expression was PARP-1 (n = 41, 56.9%), followed by ATM (n = 26, 36.1%), ARID1A (n = 10, 13.9%), MLH1 (n = 12, 16.7%), BRCA1 (n = 11, 15.3%), and MSH2 (n = 3, 4.2%). HER2 (n = 6, 8.3%) and PD-L1 (n = 3, 4.2%) were expressed in 72 patients. …”
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56339por Chen, Shan, Dang, Dongdong, Liu, Yubo, Ji, Shuwen, Zheng, Hongjian, Zhao, Chenghao, Dong, Xiaomei, Li, Cong, Guan, Yuan, Zhang, Ao, Ruan, Yanye“…The maize population presented the lower her-itabilities of the seedling emergence rate (ER), seedling plant height (SPH) and grain yield (GY) under field drought conditions. …”
Publicado 2023
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56340“…A month after that, the patient had liver abscesses and biliary fistula that were treated appropriately and her symptoms resolved. CONCLUSION: The association of liver diseases, polydactyly, and congenital heart diseases is extremely rare and was only documented few times in the literature. …”
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