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56341por Dave, Arpit, Charytonowicz, Daniel, Francoeur, Nancy J., Beaumont, Michael, Beaumont, Kristin, Schmidt, Hank, Zeleke, Tizita, Silva, Jose, Sebra, Robert“…Gene correlations with disease subtype highlighted S100A7 and MUCL1 overexpression in HER2 + cells as possible cell motility and localization drivers. …”
Publicado 2023
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56342“…In light of these results, the youngest woman with total AV block and sequelae of cerebrovascular disease and mild left ventricular dysfunction, received an implantable cardiac defibrillator (ICD) implant for primary prevention of sudden death and her siblings are undergoing an upgrade to ICD. CONCLUSION: The mutation found in this family is unique and for the first time reported in the LMNA gene in the world. …”
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56343por Liu, Yu-Peng, He, Ru-Xuan, Chen, Zhe-Hui, Kang, Lu-Lu, Song, Jin-Qing, Liu, Yi, Shi, Chun-Yan, Chen, Jun-Ya, Dong, Hui, Zhang, Yao, Li, Meng-Qiu, Jin, Ying, Qin, Jiong, Yang, Yan-Ling“…Four years later, the mother of the boy married again and came to us for prenatal diagnosis exactly 15 weeks after her last menstrual period. Subsequently, there is an increase in the amniotic fluid methylmalonate. …”
Publicado 2023
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56344“…SIMPLE SUMMARY: The mechanism which ensures a mare recognises the presence of a pregnancy and receives an embryonic signal to prevent her returning to oestrus is known as maternal recognition of pregnancy (MRP) and occurs approximately 12 days after ovulation. …”
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56345por Hu, Jiayue, Lang, Ronggang, Zhao, Weipeng, Jia, Yongsheng, Tong, Zhongsheng, Shi, Yehui“…Of all histological subtypes, 45.1% were mixed subtypes, followed by with mesenchymal differentiation (27.2%), pure squamous (15.2%) and pure spindle (12.4%) subtypes. 69.6% of MpBC were triple-negative, 25.3% and 6.5% were HR-positive and HER2-positive. MpBC patients had worse survival compared to IDC-NST patients, with 5-year RFS of 73.8 and 83.6% (HR = 1.177 95%CI (1.171–2.676) P = 0.0068), and 5-year BCSS of 79.0% and 89.7% (HR = 2.187 95%CI (1.357–3.523) P = 0.0013). …”
Publicado 2023
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56346por Kim, Yoo-Na, Lee, Kyunglim, Park, Eunhyang, Park, Junsik, Lee, Yong Jae, Nam, Eun Ji, Kim, Sang Wun, Kim, Sunghoon, Kim, Young Tae, Lee, Jung-Yun“…Based on IHC analysis, the programmed death-ligand 1 combined positive score (PD-L1 CPS) was higher in patients with squamous cell carcinoma (SCC) than in those with adeno or mucinous types (P=0.020). HER2 receptor expression of 2+ and 3+ were identified in 5 and 1 patients, respectively, and significantly varied based on histology (p=0.002). …”
Publicado 2023
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56347por Lother, Dione, Robert, Marie, Elwood, Elliot, Smith, Sam, Tunariu, Nina, Johnston, Stephen R.D., Parton, Marina, Bhaludin, Basrull, Millard, Thomas, Downey, Kate, Sharma, Bhupinder“…Treatment is determined according to tumor subtype; primarily hormone receptor status and HER2 expression. Menopausal status and site of disease relapse are also important considerations in treatment protocols. …”
Publicado 2023
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56348por Osman, K., Ahmet, K., Hilmi, T., İlker, N.O., Ercan, Ö., Devrim, Ç., Murat, S., Emre, Ç., İlhan, H., Mustafa, G., Yüksel, Ü., Bahiddin, Y., Cihan, E., Mehmet Ali, N. Ş., Emrah, E., Umut, D., Zeynep, O., Mehmet Ali, K., Ali, G., İvo, G., Erkan, Ö., Muhammet, B.H., Bülent, E., Selma, D., Sernaz, U., Mahmut, G., Hakan, G., İrfan, Ç.“…Of these, 64.0% had breast cancer (43.8% of them had the triple-negative disease, and about 2.3% had only the HER-2 mutant), 31.5% had genital cancers (92.1% of them had ovarian cancer, 3.2% had endometrium, and 1.6% had peritoneum cancer as the primary site and mostly serous adenocarcinoma was the most common histopathology and 14.3% of the patients had endometrioid adenocarcinoma), 3.5% had prostate (median time from metastasis to castration-resistant status was 28 months) and 1.0% had pancreas cancer. …”
Publicado 2023
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56349“…OBJECTIVES: Postpartum depression estimated prevalence in women is between 5 and 26% and it has adverse effects both on the mother, infant and her partner. Psychological treatments have proved to be effective for women with mild-to-moderate symptoms. …”
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56350por Li, Jinyu, Zhou, Xiajie, Li, Lixi, Ji, Longtao, Li, Jiaqi, Qu, Yunhui, Wang, Zhi, Zhao, Yutong, Zhang, Jie, Liang, Feifei, Liu, Jingjing, Gu, Wanjian, Yang, Rongxi, Ma, Fei, Dai, Liping“…Furthermore, we observed a correlation between methylation levels and tumor stage, ER, and HER2 status in BC patients. CONCLUSION: Overall, our findings suggest that altered CTSZ methylation levels in peripheral blood may be associated with breast cancer, particularly in young women, and may serve as a potential biomarker for early-stage BC.…”
Publicado 2023
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56351“…The use case looks at the daily journey of Tracy, a healthy woman aged 27 years, and her dog Mego. Using medical Internet of Things, their activities are continuously monitored and analyzed to prevent or manage any kind of health-related abnormality. …”
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56352por Kamla, Joël Igor, Bwelle, Georges Motto, Tochie, Joel Noutakdie, Tchuenkam, Landry Wakheu, Wandji, Brigitte, Kamto, Trevor, Esiéné, Agnès“…The patient underwent panniculectomy on the 26th day after the initial surgery and her post-operative course was uneventful. Wound esthetics was satisfactory three months later. …”
Publicado 2023
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56353por Clauser, Paola, Rasul, Sazan, Kapetas, Panagiotis, Fueger, Barbara J., Milos, Ruxandra-Iulia, Balber, Theresa, Berroterán-Infante, Neydher, Hacker, Marcus, Helbich, Thomas Hans, Baltzer, Pascal Andreas Thomas“…SUV(maxT) was higher if lesions were malignant (p < 0.001), had a higher proliferation rate (p = 0.011), and were HER2-positive (p = 0.041). SUV(maxLN) was higher in metastatic lymph nodes, with an ROC of 0.761 for SUV(maxT) and of 0.793 for SUV(maxLN.) …”
Publicado 2023
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56354“…Our immunohistochemical results showed that the ER was consistently strongly positive, and the PR expression was not consistent, while all the cases of HER2 were negative. CK7 was negative in one case, and CK20 and CK5/6 were not expressed in all the cases. …”
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56355por Yamauchi, Hideko, Toi, Masakazu, Takayama, Shin, Nakamura, Seigo, Takano, Toshimi, Cui, Karen, Campbell, Christine, De Vos, Liesbet, Geyer, Charles, Tutt, Andrew“…METHODS: Patients with germline BRCA1 and/or BRCA2 pathogenic variants and HER2-negative, high-risk early breast cancer who had received neoadjuvant or adjuvant chemotherapy and completed local treatment were eligible. …”
Publicado 2023
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56356por Gonsalves, Daniel Gregório, Raffa, Paulo Eduardo Albuquerque Zito, de Sousa, Gabriela Gerenutti, Rigueiral, Melissa Esposito Gomes, Estevão, Iracema Araújo, Pacheco, Cesar Cozar, Medeiros, Roger Thomaz Rotta, Franceschini, Paulo Roberto, de Aguiar, Paulo Henrique Pires“…An 82-year-old woman with Fitzpatrick skin type II, diagnosed and treated for non-Hodgkin's lymphoma 7 years ago, was admitted with mental confusion and memory loss for the past 2 months—evolving with recurring falls from her own height. One day before admission, she displayed Brown-Séquard syndrome. …”
Publicado 2023
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56357por Salomatina, Anastasiya S., Yasko, Liudmila A., Kurnikova, Maria A., Mareeva, Yulia M., Abasov, Ruslan K., Gegeliya, Nina V., Mitrofanova, Anna M., Usman, Natalia Y., Novichkova, Galina A., Druy, Alexander E.“…(E891Pfs*6), as well as her sister. The mutation was probably inherited from their deceased father, as he had gingival fibromatosis. …”
Publicado 2023
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56358por Meade-Aguilar, José A, Varela-Martinez, Yessica N, Ramirez-Eguía, Sandra P, Sanchez-Hurtado, Edgar, Mondragón-Labelle, Tania O, Bautista-Aguilar, Gabriela A, Deloya-Tomas, Ernesto, Phinder-Puente, Marian E, Pérez Nieto, Orlando R“…A 66-year-old female presented to the Emergency Room with fever, edema on her legs, productive cough, dyspnea, and hemoptysis. …”
Publicado 2023
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56359“…In the absence of direct evidence of acquired von Willebrand syndrome (AVWS) or angiodysplasia, her long-standing gastrointestinal bleeding was finally stopped after receiving transcatheter aortic valve implantation (TAVI). …”
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56360por Rabel, R. A. Chanaka, Marchioretto, Paula V., Bangert, Elizabeth A., Wilson, Kenneth, Milner, Derek J., Wheeler, Matthew B.“…In contrast, with embryo transfer technologies, a cow can pass her genetics to hundreds of calves through surrogate cows. …”
Publicado 2023
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