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  1. 56361
    “…Meanwhile, advances in the molecular profiling of BTCs has contributed to the recent proliferation of molecularly targeted therapeutics for the subset of BTCs harboring alterations in IDH1, FGFR2, MAP kinase signaling, HER2, and beyond, and there has been great interest in investigating combinations of these agents with immunotherapy. …”
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    Immunotherapy in Biliary Tract Cancers: Current Standard-of-Care and Emerging Strategies
  2. 56362
    “…We found that, although triple-negative BC (TNBC) had the highest GALNT1 expression compared to ER-positive/HER2-negative BC, GALNT1 levels in BC were not associated with clinical aggressiveness, including histological grade, AJCC stage and N-category, and patient survival, consistently in both the METABRIC and GSE96058 cohorts. …”
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    GALNT1 Expression Is Associated with Angiogenesis and Is a Prognostic Biomarker for Breast Cancer in Adolescents and Young Adults (AYA)
  3. 56363
    “…Direct and indirect indicators of Hg exposure included a) grandfather had worked as a fishing guide, and b) mother’s measured and estimated umbilical cord blood and childhood hair Hg and her fish consumption during pregnancy with this child. …”
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    The Contribution across Three Generations of Mercury Exposure to Attempted Suicide among Children and Youth in Grassy Narrows First Nation, Canada: An Intergenerational Analysis
  4. 56364
    “…ADI significantly attenuated the relationship between race and hormone receptor positive, HER2‐negative breast cancer (proportion attenuated = 8.5%, 95% CI 4.1–16.6%) and CRC cancer (proportion attenuated = 7.3%, 95% CI 3.7 to 12.8%), and there was a significant interaction between race and ADI for lung (interaction RR = 1.22, p < 0.0001) and prostate cancer (interaction RR = 1.09, p = 0.00092). …”
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    The role of area‐level socioeconomic disadvantage in racial disparities in cancer incidence in metropolitan Detroit
  5. 56365
    “…When CAR T therapy was followed by untargeted alpha immunotherapy using 7.4 kBq of (225)Ac-DOTA-trastuzumab (anti-HER2) antibody 29d later, there was only a slight improvement in response over CAR T monotherapy demonstrating the role of tumor targeting. …”
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    Sequential CAR T cell and targeted alpha immunotherapy in disseminated multiple myeloma
  6. 56366
    por Chiang, Ping-I, Chen, Chiung-Mei
    Publicado 2023
    “…CASE PRESENTATION: A 60-year-old right-handed Taiwanese woman presented with sudden onset of intense and sharp left shoulder girdle pain without radiating to the arm, followed by muscle weakness of her left arm in abduction and elevation 3 days after the onset of pain. …”
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    Increased (18) F-FDG uptake in denervated muscles in a case of Parsonage-Turner syndrome
  7. 56367
    “…The mother additionally showed apparent cataract bilaterally and cupping of the optic disc in her left eye. CONCLUSION: A novel missense variant in PAX6 gene was detected in a Chinese pedigree demonstrating bilateral FH and ASD. …”
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    A novel missense variant expands the phenotype and genotype of PAX6-associated foveal hypoplasia accompanied by various manifestations of anterior segment dysgenesis
  8. 56368
    “…Furthermore, the integrated radiomic model incorporating human epidermal growth factor receptor 2 (HER2) status showed improved performance compared to the radiomic-score model alone in all cohorts. …”
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    Development and External Validation of (18)F-FDG PET-Based Radiomic Model for Predicting Pathologic Complete Response after Neoadjuvant Chemotherapy in Breast Cancer
  9. 56369
    “…In a small cohort of prostate and breast cancer patients, we find high inter-patient and temporal intra-patient variability in the expression of tissue specific markers such as ER, HER2, AR, PSA and PSMA and EpCAM. Our study stresses the importance of the multi-omic characterization of circulating rare cells in patients with breast and prostate carcinomas, specifically highlighting overlapping and cell type defining proteo-genomic characteristics of CTCs and CECs.…”
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    Cell State and Cell Type: Deconvoluting Circulating Tumor Cell Populations in Liquid Biopsies by Multi-Omics
  10. 56370
    “…It is also important that the patient is able to express his or her symptoms and ask for help. The concept of “Alexitimia” refers to the difficulty of expressing feelings verbally, and is a frequent symptom in depressive patients (2). …”
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    “Asking for help, quite a challenge”. Time from onset of symptoms to consultation with a psychiatrist
  11. 56371
    “…Gastrointestinal parasite positivity was also associated with the owner’s knowledge about the transmission of parasites from the mother’s milk to her puppies (p = 0.001), canine intestinal parasites potentially causing weight loss, diarrhea, and vomiting (p = 0.001), and dogs potentially becoming infected with parasites from licking or sniffing the soil or grass where other animals have been (p = 0.005). …”
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    General knowledge and practice of household dog owners regarding gastrointestinal parasites in Cebu, Philippines
  12. 56372
    “…In triple-negative and human epidermal growth factor receptor 2 (HER2)-positive breast cancer patients who underwent the neoadjuvant chemotherapy, the DL-assisted revision notably accentuated higher sTIL scores in responders (26.8 ± 19.6 vs. 19.0 ± 16.4, p = 0.003). …”
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    Deep learning model improves tumor-infiltrating lymphocyte evaluation and therapeutic response prediction in breast cancer
  13. 56373
    “…Rapid antigen test for severe acute respiratory syndrome coronavirus 2 was negative at the time of her presentation to the emergency department, but polymerase chain reaction testing for coronavirus disease 2019 turned out to be positive after admission to the medical ward. …”
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    Coronavirus disease 2019 and malaria coinfection in a middle-aged Ethiopian woman presenting with acute febrile illness and bilateral pleural effusion: a case report
  14. 56374
    “…She had suffered vomiting and diarrhea for 1 week before transfer to our hospital. Her general condition was poor, and abdominal distention was noted. …”
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    A possible manifestation of pancreas divisum–pancreatic pseudocyst in an infant with no apparent history of pancreatitis: a case report
  15. 56375
    “…The functioning shunt catheter was then connected to the cerebrospinal fluid drainage system to manage her severe hydrocephalus. Finally, the contaminated abdominal cavity was copiously irrigated with saline solution and a peritoneal drain placed. …”
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    Laparoscopic intervention for late-onset perforating peritonitis due to a ventriculoperitoneal shunt: a case report and literature review
  16. 56376
    “…The long-term health outcomes of all parties involved—the uterus donor (if live donor), the recipient, her partner and any children born from the transplanted graft—are also reviewed. …”
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    Uterus transplantation: from research, through human trials and into the future
  17. 56377
    “…However, CGS3 and CGS4 differ in that CGS3 has high HER2 activation, while CGS4 has high SALL4 and KRAS activation. …”
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    Clinically conserved genomic subtypes of gastric adenocarcinoma
  18. 56378
    “…Although she presented with no symptoms related to nicotine poisoning, abdominal X-ray examination revealed a metal object in her stomach. According to a statement released by the Japan Poison Information Center, the TEREA™ heated tobacco stick contains a metallic susceptor with a rectangular shape and sharp corners. …”
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    Extraction of a metallic susceptor after accidental ingestion of the heated tobaccostick TEREA™: a case report
  19. 56379
    “…Following initiation of steroid therapy for IS, the patient developed clinically apparent insulin requiring diabetes. Her epilepsy was ultimately refractory to multiple antiseizure medications, thus the ketogenic diet (KD) was initiated. …”
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    Safe use of the ketogenic diet in an infant with microcephaly, epilepsy, and diabetes syndrome: a case report
  20. 56380
    “…We found an unusual germline JAK2 mutation L604F in homozygous form in a young PV patient, along with a low allele burden JAK2 V617F mutation, and in her apparently healthy sister. Their father with a PV-like disease had L604F in a heterozygous state, without V617F. …”
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    A novel germline hyperactivating JAK2 mutation L604F
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