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56601por Spitzwieser, Melanie, Entfellner, Elisabeth, Werner, Bettina, Pulverer, Walter, Pfeiler, Georg, Hacker, Stefan, Cichna-Markl, Margit“…Methylation-sensitive high resolution melting (MS-HRM) analysis was applied to determine methylation levels in the promoters of APC, BRCA1, CDKN2A (p16), ESR1, HER2/neu and PTEN, in CDKN2A exon 2 and in LINE-1, as indicator for the global DNA methylation extent. …”
Publicado 2017
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56602por Kane, Bryan G., Guillaume, Alexander W. D., Evans, Elizabeth M., Goyke, Terrence E., Eygnor, Jessica K., Semler, Lauren, Dusza, Stephen W., Greenberg, Marna Rayl“…Of these, we excluded 39 for the following reasons: incorrect disease coding; the patient was admitted and treated as an inpatient for his/her disease; or the patient left the ED after refusing care. …”
Publicado 2017
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56603por Heublein, Sabine, Mayr, Doris, Meindl, Alfons, Kircher, Alexandra, Jeschke, Udo, Ditsch, Nina“…BACKGROUND: BRCA1 mutated breast cancers are commonly diagnosed as negative for classical hormone receptors i.e. estrogen receptor, progesterone receptor and/or Her2. Due to these common targets being absent the application of anti-endocrine therapies is rather limited and a certain focus has been set on discovering alternative target molecules. …”
Publicado 2017
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56604“…CONCLUSION: Even though every woman has the right to participate in her own health care decision making, more than two fifths of them have no role in making health care decisions about their own health. …”
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56605por Kovalskys, Irina, Rausch Herscovici, Cecile, Indart Rougier, Paula, De Gregorio, María José, Zonis, Luciana, Orellana, Liliana“…Outcomes are measured at baseline and 12 months post intervention, and will include data collected from the child and her/his mother/father or guardian. Primary outcome measures are: PA and sedentary behaviour (measured with accelerometers). …”
Publicado 2017
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56606por Arildsen, Nicolai Skovbjerg, Jönsson, Jenny-Maria, Bartuma, Katarina, Ebbesson, Anna, Westbom-Fremer, Sofia, Måsbäck, Anna, Malander, Susanne, Nilbert, Mef, Hedenfalk, Ingrid A.“…However, overexpression of ERBB2 was not reflected by HER2 amplification or protein overexpression in the OCCC validation cohort. …”
Publicado 2017
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56607por Smith, Shari E., Mellor, Paul, Ward, Alison K., Kendall, Stephanie, McDonald, Megan, Vizeacoumar, Frederick S., Vizeacoumar, Franco J., Napper, Scott, Anderson, Deborah H.“…RESULTS: The cell lines that were characterized included 10 estrogen receptor (ER)-positive, 12 human epidermal growth factor receptor 2 (HER2)-amplified and 18 triple negative breast cancer cell lines, in addition to 4 non-tumorigenic breast cell lines. …”
Publicado 2017
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56608por Dun-Dery, Frederick, Adokiya, Martin Nyaaba, Walana, Williams, Yirkyio, Ernestina, Ziem, Juventus B.“…Expectant mothers’ knowledge of Mother-To-Child Transmission (MTCT) of the disease is significant in preventing the spread from an infected mother to her child. This study sought to assess the expectant mothers’ knowledge of Mother-To-Child Transmission of viral hepatitis B in the Wa Municipality and Lawra District of Upper West Region, Ghana. …”
Publicado 2017
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56609“…A 41-year-old T1DM woman developed lipoatrophy on her upper thighs, arms and abdomen 14 months after injecting detemir plus aspart at the same sites. …”
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56610por Grindedal, Eli Marie, Heramb, Cecilie, Karsrud, Inga, Ariansen, Sarah Louise, Mæhle, Lovise, Undlien, Dag Erik, Norum, Jan, Schlichting, Ellen“…Carriers differed from non-carriers in terms of age at diagnosis, family history, grade, ER/PR-status, triple negativity (TNBC) and Ki67, but not in HER2 and TNM status. One mutation positive female relative was identified per mutation positive BC patient. …”
Publicado 2017
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56611por Hu, Bolin, Wu, Pengcheng, Zhou, Yibiao, Peng, Yan, Tang, Xiaoping, Ding, Weijiang, Zhang, Ming, Qi, Xueliang“…High-dose intravenous gamma-globulin combined with methylprednisolone gradually improved her condition. CONCLUSION: We report the first case of NPSLE presenting with medulla oblongata and spinal cord involvement, manifesting as the “owl’s eye” sign in MRI.…”
Publicado 2017
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56612por Liu, Minetta C, Pitcher, Brandelyn N, Mardis, Elaine R, Davies, Sherri R, Friedman, Paula N, Snider, Jacqueline E, Vickery, Tammi L, Reed, Jerry P, DeSchryver, Katherine, Singh, Baljit, Gradishar, William J, Perez, Edith A, Martino, Silvana, Citron, Marc L, Norton, Larry, Winer, Eric P, Hudis, Clifford A, Carey, Lisa A, Bernard, Philip S, Nielsen, Torsten O, Perou, Charles M, Ellis, Matthew J, Barry, William T“…The prognostic value of PAM50 intrinsic subtype was greater than estrogen receptor/HER2 immunohistochemistry classification. PAM50 gene signatures were highly prognostic but did not predict for improved outcomes with DD anthracycline- and taxane-based therapy. …”
Publicado 2016
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56613por Rutty, Guy N, Morgan, Bruno, Robinson, Claire, Raj, Vimal, Pakkal, Mini, Amoroso, Jasmin, Visser, Theresa, Saunders, Sarah, Biggs, Mike, Hollingbury, Frances, McGregor, Angus, West, Kevin, Richards, Cathy, Brown, Laurence, Harrison, Rebecca, Hew, Roger“…METHODS: In this single-centre (Leicester, UK), prospective, controlled study, we selected cases of natural and non-suspicious unnatural death referred to Her Majesty's (HM) Coroners. We excluded cases younger than 18 years, known to have had a transmittable disease, or who weighed more than 125 kg. …”
Publicado 2017
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56614por Hoek, Rianne J. A., Havermans, Bo M., Houtman, Irene L. D., Brouwers, Evelien P. M., Heerkens, Yvonne F., Zijlstra-Vlasveld, Moniek C., Anema, Johannes R., van der Beek, Allard J., Boot, Cécile R. L.“…For each intervention team, one employee is responsible for applying the strategy within his/her team using the digital platform and visiting the collaborative learning network. …”
Publicado 2017
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56615por Custodio, A, Carmona-Bayonas, A, Jiménez-Fonseca, P, Sánchez, M L, Viudez, A, Hernández, R, Cano, J M, Echavarria, I, Pericay, C, Mangas, M, Visa, L, Buxo, E, García, T, Rodríguez Palomo, A, Álvarez Manceñido, F, Lacalle, A, Macias, I, Azkarate, A, Ramchandani, A, Fernández Montes, A, López, C, Longo, F, Sánchez Bayona, R, Limón, M L, Díaz-Serrano, A, Hurtado, A, Madero, R, Gómez, C, Gallego, J“…RESULTS: The nomogram includes seven predictors associated with OS: HER2-positive tumours treated with trastuzumab, Eastern Cooperative Oncology Group performance status, number of metastatic sites, bone metastases, ascites, histological grade, and neutrophil-to-lymphocyte ratio. …”
Publicado 2017
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56616por Seedat, Farah, Stinton, Chris, Patterson, Jacoby, Geppert, Julia, Tan, Bee, Robinson, Esther R., McCarthy, Noel Denis, Uthman, Olalekan A., Freeman, Karoline, Johnson, Samantha Ann, Fraser, Hannah, Brown, Colin Stewart, Clarke, Aileen, Taylor-Phillips, Sian“…In this systematic review, we appraised and synthesised the evidence on the adverse events of IAP in the mother and/or her child. METHODS: We searched MEDLINE, MEDLINE In-Process & Other Non-Indexed Citations, EMBASE, Cochrane, and Science Citation Index from date of inception until October 16th 2016. …”
Publicado 2017
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56617por Højgaard, Liselotte, Löwenberg, Bob, Selby, Peter, Lawler, Mark, Banks, Ian, Law, Kate, Albreht, Tit, Armand, Jean-Pierre, Barbacid, Mariano, Barzach, Michèle, Bergh, Jonas, Cameron, David, Conte, Pierfranco, de Braud, Filippo, de Gramont, Aimery, De Lorenzo, Francesco, Diehl, Volker, Diler, Sarper, Erdem, Sema, Geissler, Jan, Gore-Booth, Jola, Henning, Geoffrey, Horgan, Denis, Jassem, Jacek, Johnson, Peter, Kaasa, Stein, Kapitein, Peter, Karjalainen, Sakari, Kelly, Joan, Kienesberger, Anita, La Vecchia, Carlo, Lacombe, Denis, Lindahl, Tomas, Luzzatto, Lucio, Malby, Rebecca, Mastris, Ken, Meunier, Françoise, Murphy, Martin, Naredi, Peter, Nurse, Paul, Oliver, Kathy, Pearce, Jonathan, Pelouchov, Jana, Piccart, Martine, Pinedo, Bob, Spurrier-Bernard, Gilly, Sullivan, Richard, Tabernero, Josep, Van de Velde, Cornelis, van Herk, Bert, Vedsted, Peter, Waldmann, Anita, Weller, David, Wilking, Nils, Wilson, Roger, Yared, Wendy, Zielinski, Christoph, zur Hausen, Harald, Le Chevalier, Thierry, Johnston, Patrick“…The right of every European citizen to receive the most accurate information and to be proactively involved in his/her care. 2. The right of every European citizen to optimal and timely access to a diagnosis and to appropriate specialised care, underpinned by research and innovation. 3. …”
Publicado 2017
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56618“…She had no recurrence of seizures but had acute liver injury subsequently which gradually improved with supportive care. Her liver functions found to be completely normal 1 week after the discharge. …”
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56619por Ellinger, Philipp, Stindt, Jan, Dröge, Carola, Sattler, Katharina, Stross, Claudia, Kluge, Stefanie, Herebian, Diran, Smits, Sander H J, Burdelski, Martin, Schulz-Jürgensen, Sebastian, Ballauff, Antje, Schulte am Esch, Jan, Mayatepek, Ertan, Häussinger, Dieter, Kubitz, Ralf, Schmitt, Lutz“…At the age of 17 years relative amounts of conjugated BS in her bile were normal, while total BS were less than 3% as compared to controls. …”
Publicado 2017
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56620“…In 2014, Ghana updated her policy on intermittent preventive treatment of malaria in pregnancy with sulfadoxine–pyrimethamine (IPTp-SP) to reflect the updated policy of the WHO. …”
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