“…DISCUSSION: In this trial, we will test the feasibility of an integrated palliative care approach starting when the haematologist decides to propose the last active treatment to the patient, according to his/her clinical judgement. We decided to test this criterion because it is able to intercept a wide range of patients’needs. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Also relevant was the extent to which a man’s intentions were considered inappropriate; the adolescent girl or young woman was considered vulnerable; and the adolescent girl or young woman was considered responsible for ‘her situation’. CONCLUSIONS: Existing social norms that condemn sex with a minor or sex that involves deception, sexual coercion or misleading an immature girl, present opportunities to mobilise communities to protect adolescent girls and young women at risk. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In addition, the female’s reproductive output increased with multiple matings, although when paired with a new virgin male every night, more than 3 matings decreased her reproductive output, so that the Bateman gradient for females fit a quadratic model better than a linear model. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…She presented to our facility for revision corpectomy and spinal fusion. Given her history of nonunion, endocrinology was consulted for evaluation of metabolic bone disease. …”
Enlace del recurso
Enlace del recurso

“…She was then started on a short-acting glucocorticoid regimen. While her adrenal insufficiency was initially thought to be secondary to inhaled steroids, subsequent mutation analysis suggested that she was prone to autoimmunity. …”
Enlace del recurso
Enlace del recurso

“…Prior to starting TPTD, her Ca levels were normal at 9.3 mg/dl, PTH was 24 pg/ml and vitamin D 25 OH was 33 ng/ml. …”
Enlace del recurso
Enlace del recurso

“…A 49-year-old female with past medical history of Huntington’s disease presents to the ED after being found unresponsive at her assisted-living facility. She was noted to be hypoglycemic with a glucose of 21 and responded to dextrose. …”
Enlace del recurso
Enlace del recurso

“…A risk factor-centered approach to AIP genetic screening may result in missing germline mutations, therefore, there is a need to establish if such a situation negatively impacts a patient’s and his/her family outcomes.…”
Enlace del recurso
Enlace del recurso

“…She was also started on Nivolumab. Her blood pressure was 98/65 mmHg on the presentation. …”
Enlace del recurso
Enlace del recurso

“…EMG confirmed myotonia however genetic testing was not obtained due to cost. Due to her cognitive dysfunction and depression, she had difficult to control diabetes with HbA1c of 9.9%, and multiple previous admissions for DKA. …”
Enlace del recurso
Enlace del recurso

“…Abdominal pain, hepatomegaly and elevated LFTs resolved over a 2 month duration with improvement in her blood glucose control. Conclusions: GH is an established yet rare complication of poorly controlled type 1 diabetes. …”
Enlace del recurso
Enlace del recurso

“…She then developed worsening altered mental status hence admission to the hospital. Her vital signs were within normal limits. Physical examination revealed no abdominal tenderness. …”
Enlace del recurso
Enlace del recurso

“…Clinical Case A 40 year-old woman with NF-1 and recently diagnosed left breast invasive ductal carcinoma, estrogen positive, progesterone positive, HER-2 negative BRCA2 positive breast cancer and right breast lobular carcinoma in situ underwent staging CT scan. …”
Enlace del recurso
Enlace del recurso

“…ENT evaluation determined that her lymphadenopathy was benign and consistent with Hashimoto’s thyroiditis. …”
Enlace del recurso
Enlace del recurso

“…On exam, blood pressure was 93/54 mmHg and pulse rate was 99. Her abdomen and arms looked hyperpigmented. Lab test revealed plasma glucose of 68 mg/dl, serum sodium of 129 mmol/l (133-145), potassium of 4.9 mmol/l (3.6 – 5.2), bicarbonate of 20 mmol/l (22 – 29). …”
Enlace del recurso
Enlace del recurso

“…Patient was determined to be of high surgical risk due to her comorbidities and she did not consent for thyroidectomy. …”
Enlace del recurso
Enlace del recurso

“…She noted a gradually enlarging submental mass during the preceding year, which had been present since her adolescent years. Examination was notable for a 2-cm firm, non-tender mass at the submental region that slightly moved with deglutition. …”
Enlace del recurso
Enlace del recurso

“…Complete remission was achieved with normalization of TFTs, resolution of her Cushingoid and encephalopathic features. This case illustrates SREAT as a diagnosis of exclusion. …”
Enlace del recurso
Enlace del recurso

“…She resumed taking alpelisib and had an up titration of the insulin regimen. During her hospital stay, she suffered from hyperglycemia as high as 558 mg/dl. …”
Enlace del recurso
Enlace del recurso