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  1. 57161
    “…Immunohistochemistry revealed high estrogen receptor (90.5%), high progesterone receptor (71.6%), and low HER-2 (26.4%) positivity. CONCLUSION: IMPC mammography, sonography, and MRI clinical imaging features highly suggest malignancy. …”
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    Invasive micropapillary breast carcinoma: A retrospective study on the clinical imaging features and pathologic findings
  2. 57162
    “…But it created a seeming paradox: how can natural selection maintain social behaviour when a female apparently enjoys her highest per‐capita output by working alone? …”
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    Five decades of misunderstanding in the social Hymenoptera: a review and meta‐analysis of Michener's paradox
  3. 57163
    “…CASE PRESENTATION: A 43-year-old woman presented with mild gait imbalance for 2 years. Her family history was positive for type 2 spinocerebellar ataxia (SCA2). …”
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    Moyamoya associated with Turner syndrome in a patient with type 2 spinocerebellar ataxia—Occam’s razor or Hickam’s dictum: a case report
  4. 57164
    “…Finally, obesity was associated with ER+HER2 negative disease (HR(adj) 1.37, 95% CI 1.05–1.78) and similarly luminal A tumors (HR(adj) 1.43, 95% CI 1.02–2.01). …”
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    Postmenopausal overweight and breast cancer risk; results from the KARMA cohort
  5. 57165
    “…The 3rd NGS analysis revealed the retention of the BRAF(V600E) mutation (AF =0.39%). Her treatment was switched to pembrolizumab (the 5(th) line), and the disease remained stable for another 6 months as of the last follow-up in November 2021. …”
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    Successful re-challenge of dabrafenib-trametinib combination therapy in advanced BRAF(V600E)-mutant non-small cell lung cancer after previous cytotoxic chemotherapy, targeted therapy, and immunotherapy: a case report
  6. 57166
    “…ABSTRACT: Pregnancy is one of the most challenging processes the human body is exposed to: the healthy mother can carry to term a genetically different new-born, while her immune system adapts to tolerate this new status and avoids rejection. …”
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    Preparing for Pregnancy in Women with Systemic Lupus Erythematosus—A Multidisciplinary Approach
  7. 57167
    “…The expression of IGF2R was significantly associated with clinical risk factors such as TNBC, estrogen receptor (ER)–negative expression, human epidermal growth factor receptor 2 (HER2)–positive expression, and age ≤60 years old in METABRIC patients. …”
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    Insulin-like growth factor 2 receptor is a key immune-related gene that is correlated with a poor prognosis in patients with triple-negative breast cancer: A bioinformatics analysis
  8. 57168
    “…CASE PRESENTATION: A 37-year-old woman was evaluated for headaches and double vision during the third trimester of her pregnancy. A visual field exam showed bitemporal hemianopsia. …”
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    LBODP076 Hypophysitis Misdiagnosed As Pituitary Macroadenoma During Pregnancy
  9. 57169
    por Patel, Toral, Arora, Gunjan
    Publicado 2022
    “…She was managed in the ICU with broad spectrum intravenous antibiotics and pressor support. Her workup revealed hypercalcemia with serum calcium 12 mg/dL (8.6 - 10.3), albumin 3.4 g/dL (3.5 - 5.7) in the setting of inappropriately elevated parathormone PTH at 120.4 pg/ml (12 - 88). …”
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    LBSAT309 Recurrent Nephrolithiasis As A Presenting Feature Of Primary Hyperparathyroidism
  10. 57170
    “…The regimen of lanreotide, osilodrostat and ketoconazole improved her24-hoururine cortisol to 15 from 2,109 ug/24hr. …”
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    ODP303 Cushing's Syndrome Due to Ectopic Adrenocorticotropic Hormone-Secreting Metastatic Neuroendocrine Tumor
  11. 57171
    por Elshimy, Ghada, Raj, Rishi
    Publicado 2022
    “…Extensive rheumatological workup including ANCA level was performed with negative results. Since her thyroid function tests (TSH and free T4) were normal on a low dose of methimazole for an extended period, we discontinued methimazole, however, skin rash didn't improve. …”
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    PSAT353 Can Generalized Granuloma Annulare occur in patients with Graves’ disease?
  12. 57172
    “…During the neonatal period, she had multiple complications including GERD, FTT (G-tube was placed), recurrent UTIs, congenital heart disease (mild RVH and ASD) and hypoglycemia. Regarding her hypoglycemia, the initial work up was suggestive of hyperinsulinism with a critical sample remarkable for a BG: 57 mg/dl (60-100mg/dl), Insulin level: 8.3 uUm/mL Subsequent glucagon challenge test confirmed hyperinsulinism. …”
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    PSUN339 Persistent Hypoglycemia and Hyperinsulinism in a Patient With Kabuki Syndrome Type 1.
  13. 57173
    “…METHODS: To determine the contribution of Ins2-producing neurons to feeding behavior in mice, we used the cross of transgenic RipHER-cre mouse and channelrhodopsin-2 expressing animals, which allowed us to optogenetically stimulate neurons expressing Ins2 in vivo. …”
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    Hindbrain insulin controls feeding behavior
  14. 57174
    “…RESULTS: LP-WGS data demonstrated copy-number gains/losses in individual CTCs in regions including FGFR1, JAK2 and CDK6 in five patients, ERBB2 amplification in two HER2-negative patients and BRCA loss in two patients. …”
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    Shallow WGS of individual CTCs identifies actionable targets for informing treatment decisions in metastatic breast cancer
  15. 57175
    “…BRCAness was associated with response to chemotherapy and correlated strongly with response to PARP inhibitor in both triple-negative and ER-positive/HER2-negative breast cancer. CONCLUSIONS: We established a novel BRCAness score using BRCA-mutation-related gene expressions and found that it associates with DNA repair and predicts response to PARP inhibitors regardless of BRCA mutation. …”
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    Development of a novel BRCAness score that predicts response to PARP inhibitors
  16. 57176
    “…As proof of principle, cells harvested from a concurrent parallel sample provided by each participant were evaluated using one of three additional evaluation techniques: molecular profiling by qRT-PCR, RNA sequencing, or cytogenetic analysis of HER2 amplification by FISH. The study demonstrated that the Parsortix(®) PC1 System can effectively capture and harvest CTCs from the peripheral blood of MBC patients and that the harvested cells can be evaluated using orthogonal methodologies such as gene expression and/or Fluorescence In Situ Hybridization (FISH).…”
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    A Multi-Center Clinical Study to Harvest and Characterize Circulating Tumor Cells from Patients with Metastatic Breast Cancer Using the Parsortix(®) PC1 System
  17. 57177
    “…We report the prespecified VERONICA primary results, a randomized phase II clinical trial evaluating venetoclax and fulvestrant in estrogen receptor (ER)-positive, HER2-negative metastatic breast cancer, post–cyclin-dependent kinase (CDK) 4/6 inhibitor progression. …”
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    VERONICA: Randomized Phase II Study of Fulvestrant and Venetoclax in ER-Positive Metastatic Breast Cancer Post-CDK4/6 Inhibitors – Efficacy, Safety, and Biomarker Results
  18. 57178
    “…The inoculation of a mother during pregnancy was found to be effective in protecting her progeny. RESULTS: This is a review article, thus not applicable. …”
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    Impact of COVID-19 on children
  19. 57179
    “…Current therapies for HER2-positive breast cancer have limited efficacy in patients with triple-positive breast cancer (TPBC). …”
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    A multicentre single arm phase 2 trial of neoadjuvant pyrotinib and letrozole plus dalpiciclib for triple-positive breast cancer
  20. 57180
    “…Case 2, a 37-day-old female presented with fever, a history of neonatal cholestasis, and huge hepatosplenomegaly. Her whole-exome sequencing report manifested that the patient had the same mutation as case 1. …”
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    Familial Hemophagocytic Lymphohistiocytosis secondary to UNC13D mutation: a report of two cases
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