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57381por Charaghvandi, R. K., van Asselen, B., Philippens, M. E. P., Verkooijen, H. M., van Gils, C. H., van Diest, P. J., Pijnappel, R. M., Hobbelink, M. G. G., Witkamp, A. J., van Dalen, T., van der Wall, E., van Heijst, T. C., Koelemij, R., van Vulpen, M., van den Bongard, H. J. G. D.“…Patients with core biopsy proven non-lobular invasive breast cancer, (estrogen receptor positive, Her2 negative, maximum tumor size 3.0 cm on diagnostic MRI) and a negative sentinel node biopsy are eligible. …”
Publicado 2017
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57382por Portocarrero, Maria Esther Leiva, Giguère, Anik M. C., Lépine, Johanie, Garvelink, Mirjam M., Robitaille, Hubert, Delanoë, Agathe, Lévesque, Isabelle, Wilson, Brenda J., Rousseau, François, Légaré, France“…Participating women watched a video depicting a prenatal care follow-up during which a pregnant woman, her partner and a health professional used a PtDA to decide about prenatal screening for DS. …”
Publicado 2017
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57383por Klaassen, Bart, van Beijnum, Bert-Jan F., Held, Jeremia P., Reenalda, Jasper, van Meulen, Fokke B., Veltink, Peter H., Hermens, Hermie J.“…Altogether, it remains a questions how to determine what the patient is doing and where the patient is doing his or her activities.…”
Publicado 2017
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57384“…Clinical examination revealed two café-au-lait lesions, lichen planus, and a dermoid cyst. Her sister had been diagnosed in childhood with an aggressive brain tumour followed by colorectal cancer. …”
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57385por Coulson, Rhiannon, Liew, Seng H., Connelly, Angela A., Yee, Nicholas S., Deb, Siddhartha, Kumar, Beena, Vargas, Ana C., O’Toole, Sandra A., Parslow, Adam C., Poh, Ashleigh, Putoczki, Tracy, Morrow, Riley J., Alorro, Mariah, Lazarus, Kyren A., Yeap, Evie F.W., Walton, Kelly L., Harrison, Craig A., Hannan, Natalie J., George, Amee J., Clyne, Colin D., Ernst, Matthias, Allen, Andrew M., Chand, Ashwini L.“…Previous studies demonstrate that the Angiotensin Receptor Type I (AT(1)R) is linked to breast cancer pathogenesis, with unbiased analysis of gene-expression studies identifying significant up-regulation of AGTR1, the gene encoding AT(1)R in ER(+ve)/HER2(−ve) tumors correlating with poor prognosis. …”
Publicado 2017
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57386por Wanders, Johanna O. P., Holland, Katharina, Karssemeijer, Nico, Peeters, Petra H. M., Veldhuis, Wouter B., Mann, Ritse M., van Gils, Carla H.“…BACKGROUND: In the light of the breast density legislation in the USA, it is important to know a woman’s breast cancer risk, but particularly her risk of a tumor that is not detected through mammographic screening (interval cancer). …”
Publicado 2017
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57387por Shenouda, Mira M., Gillgrass, Amy, Nham, Tina, Hogg, Richard, Lee, Amanda J., Chew, Marianne V., Shafaei, Mahsa, Aarts, Craig, Lee, Dean A., Hassell, John, Bane, Anita, Dhesy-Thind, Sukhbinder, Ashkar, Ali A.“…Moreover, we tested the ability of expanded NK cells to lyse the triple negative breast cancer and HER2-positive breast cancer cell lines MDA-MB-231 and MDA-MB-453, respectively. …”
Publicado 2017
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57388por Patterson, Dillon G., Roberts, Justin T., King, Valeria M., Houserova, Dominika, Barnhill, Emmaline C., Crucello, Aline, Polska, Caroline J., Brantley, Lucas W., Kaufman, Garrett C., Nguyen, Michael, Santana, Megann W., Schiller, Ian A., Spicciani, Julius S., Zapata, Anastasia K., Miller, Molly M., Sherman, Timothy D., Ma, Ruixia, Zhao, Hongyou, Arora, Ritu, Coley, Alexander B., Zeidan, Melody M., Tan, Ming, Xi, Yaguang, Borchert, Glen M.“…Excitingly, we recently determined sdRNA-93 expressions in small RNA-seq data corresponding to 116 patient tumors and normal breast controls, and while we find little sdRNA-93 expression in any of the controls and only sporadic expression in most subtypes, we find robust expression of sdRNA-93 in 92.8% of Luminal B Her2+tumors. Of note, our analyses also indicate that at least one of sdRNA-93’s endogenous roles is to regulate the expression of Pipox, a sarcosine metabolism-related protein whose expression significantly correlates with distinct molecular subtypes of breast cancer. …”
Publicado 2017
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57389por Iddawela, Mahesh, Rueda, Oscar, Eremin, Jenny, Eremin, Oleg, Cowley, Jed, Earl, Helena M., Caldas, Carlos“…Gene expression assessed by DASL correlated with immunohistochemistry (IHC) analysis for oestrogen receptor (ER) [area under the curve (AUC) = 0.95], progesterone receptor (PR)(AUC = 0.90) and human epidermal growth factor type-2 receptor (HER-2) (AUC = 0.96). Differential expression analysis between ER+ and ER– cancers identified over-expression of TTF1, LAF-4 and C-MYB (p ≤ 0.05), and between pCR vs non-pCRs, over-expression of CXCL9, AREG, B-MYB and under-expression of ABCG2. …”
Publicado 2017
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57390por Sawe, Rispah T., Mining, Simeon K., Ofulla, Ayub V., Patel, Kirtika, Guyah, Bernard, Chumba, David, Prosperi, Jenifer R., Kerper, Maggie, Shi, Zonggao, Sandoval-Cooper, Mayra, Taylor, Katherine, Badve, Sunil, Stack, M. Sharon, Littlepage, Laurie E.“…Based on this analysis, the molecular subtype distribution was heterogeneous with luminal B (41%), basal/triple negative (TN) (37%), luminal A (14%) and HER2 (8%) breast cancer subtypes. While the basal/TN subtype had a much higher proliferative index (Ki-67+) than did the other molecular subtypes, we did not see a significant correlation between TIL density and either subtype or tumor grade. …”
Publicado 2017
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57391por Curtit, Elsa, Pivot, Xavier, Henriques, Julie, Paget-Bailly, Sophie, Fumoleau, Pierre, Rios, Maria, Bonnefoi, Hervé, Bachelot, Thomas, Soulié, Patrick, Jouannaud, Christelle, Bourgeois, Hugues, Petit, Thierry, Tennevet, Isabelle, Assouline, David, Mathieu, Marie-Christine, Jacquin, Jean-Philippe, Lavau-Denes, Sandrine, Darut-Jouve, Ariane, Ferrero, Jean-Marc, Tarpin, Carole, Lévy, Christelle, Delecroix, Valérie, Trillet-Lenoir, Véronique, Cojocarasu, Oana, Meunier, Jérôme, Pierga, Jean-Yves, Kerbrat, Pierre, Faure-Mercier, Céline, Blanché, Hélène, Sahbatou, Mourad, Boland, Anne, Bacq, Delphine, Besse, Céline, Thomas, Gilles, Deleuze, Jean-François, Pauporté, Iris, Romieu, Gilles, Cox, David G.“…The risk score was not associated with usual prognostic and predictive factors (age; tumor, node, metastasis (TNM) status; Scarff-Bloom-Richardson grade; inflammatory features; estrogen receptor status; progesterone receptor status; human epidermal growth factor receptor 2 (HER2) status) and did not correlate with breast cancer subtypes. …”
Publicado 2017
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57392por Severson, Tesa M., Wolf, Denise M., Yau, Christina, Peeters, Justine, Wehkam, Diederik, Schouten, Philip C., Chin, Suet-Feung, Majewski, Ian J., Michaut, Magali, Bosma, Astrid, Pereira, Bernard, Bismeijer, Tycho, Wessels, Lodewyk, Caldas, Carlos, Bernards, René, Simon, Iris M., Glas, Annuska M., Linn, Sabine, van ‘t Veer, Laura“…This BRCA1ness signature was then tested in HER2-negative patients (n = 116) from the I-SPY 2 TRIAL who received an oral PARP inhibitor veliparib in combination with carboplatin (V-C), or standard chemotherapy alone. …”
Publicado 2017
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57393por Yamashita, Yuji, Nishiumi, Shin, Kono, Seishi, Takao, Shintaro, Azuma, Takeshi, Yoshida, Masaru“…Furthermore, we classified the breast cancer tissues into ER-positive, PgR-positive, HER2-negative breast cancer (EP+H-) and TN, and then the differences in their metabolic pathways were investigated. …”
Publicado 2017
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57394por Stemmer, Salomon M., Steiner, Mariana, Rizel, Shulamith, Soussan-Gutman, Lior, Ben-Baruch, Noa, Bareket-Samish, Avital, Geffen, David B., Nisenbaum, Bella, Isaacs, Kevin, Fried, Georgeta, Rosengarten, Ora, Uziely, Beatrice, Svedman, Christer, McCullough, Debbie, Maddala, Tara, Klang, Shmuel H., Zidan, Jamal, Ryvo, Larisa, Kaufman, Bella, Evron, Ella, Karminsky, Natalya, Goldberg, Hadassah, Shak, Steven, Liebermann, Nicky“…The analysis included N0 ER + HER2-negative breast cancer patients who were RS-tested from 1/2006 through 12/2010. …”
Publicado 2017
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57395por Reinkensmeyer, David J., Blackstone, Sarah, Bodine, Cathy, Brabyn, John, Brienza, David, Caves, Kevin, DeRuyter, Frank, Durfee, Edmund, Fatone, Stefania, Fernie, Geoff, Gard, Steven, Karg, Patricia, Kuiken, Todd A., Harris, Gerald F., Jones, Mike, Li, Yue, Maisel, Jordana, McCue, Michael, Meade, Michelle A., Mitchell, Helena, Mitzner, Tracy L., Patton, James L., Requejo, Philip S., Rimmer, James H., Rogers, Wendy A., Zev Rymer, W., Sanford, Jon A., Schneider, Lawrence, Sliker, Levin, Sprigle, Stephen, Steinfeld, Aaron, Steinfeld, Edward, Vanderheiden, Gregg, Winstein, Carolee, Zhang, Li-Qun, Corfman, Thomas“…The average US citizen can expect to live 20% of his or her life with a disability. Rehabilitation technologies play a major role in improving the quality of life for people with a disability, yet widespread and highly challenging needs remain. …”
Publicado 2017
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57396por Haas, Josephine, Persson, Martina, Brorsson, Anna Lena, Toft, Eva Hagström, Olinder, Anna Lindholm“…Guided self-determination (GSD) is a person-centred reflection and problem-solving method intended to support the patient’s own motivation in the daily care of her diabetes and help develop skills to manage difficulties in diabetes self-management. …”
Publicado 2017
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57397por Ali, Rizwan, Samman, Nosaibah, Al Zahrani, Hajar, Nehdi, Atef, Rahman, Sabhi, Khan, Abdul Latif, Al Balwi, Mohamed, Alriyees, Lolwah Abdullah, Alzaid, Manal, Al Askar, Ahmed, Boudjelal, Mohamed“…RESULTS: These cells are ER/PR-positive and HER2-negative. The epithelial nature of these cells was confirmed by flow cytometry analysis using epithelial cell markers. …”
Publicado 2017
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57398The implication of the shortage of health workforce specialist on universal health coverage in Kenyapor Miseda, Mumbo Hazel, Were, Samuel Odhiambo, Murianki, Cirindi Anne, Mutuku, Milo Peter, Mutwiwa, Stephen N.“…RESULTS: Overall, the findings revealed average skill gaps on selected specialists (healthcare professional whose practice is limited to a particular area, such as a branch of medicine, surgery, or nursing, especially, one who by virtue of advanced training is certified by a specialty board as being qualified to so limit his or her practice, Free dictionary) at 85 and 62% when compared to the guideline and as perceived by the CDH respectively. …”
Publicado 2017
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57399por Strüver, Vanessa“…From an ethical point of view, the benefits each individual patient receives from his or her participation in a clinical trial might also be seen as a societal benefit, especially when the drug or device tested, if approved for marketing, would eventually be made available for other similar patients from the country in which the clinical trial was conducted.…”
Publicado 2017
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57400por Kiley-Worthington, Marthe“…This recognizes our common mental traits (anthropomorphism) takes into account different species specialties and examines the past experience of that individual to indicate how his/her world view is molded by lifetime experiences (conditional). …”
Publicado 2017
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