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57721por Jaeger, Gunilla, Röjvik, AnnCatrin, Hjelmquist, Erland, Hansla, André, Falkman, Kerstin W.“…RESULTS: The instrument consists of 119 quantitative and 65 qualitative items and covers ten domains: social and communicative ability, emotions and behaviours, communication and language, ability to manage his/her disability and everyday life, activities of daily life, gross and fine motor skills, perception and worldview, prerequisites for learning and basic school abilities. …”
Publicado 2022
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57722por Zheng, Chun-Hui, Xu, Kai, Shan, Wen-Ping, Zhang, Ya-Kun, Su, Zhi-De, Gao, Xiang-Jin, Wang, Yu-Jue, Qi, Jian-Yu, Ding, Xiao-Yan, Wang, Chun-Ping, Wang, Yong-sheng“…From subgroup analyses, the CSM% of luminal A, luminal B, Her2+, and triple negative were 29.7% (16.5%, 42.8%); 47.2% (19.1%, 75.3%); 59.0% (39.7%, 78.3%); 66.2% (52.8%, 79.6%), respectively. …”
Publicado 2022
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57723por Alqudaihi, Heba Mohammad Abdulla, Lee, Sae Byul, Son, Byung Ho, Ahn, Sei-Hyun, Lee, Jong Won, Ko, Beom Seok, Kim, Hee Jeong, Chung, Il Yong, Kim, Jisun, Gong, Gyungyub“…Data regarding age at diagnosis, preoperative biopsy results, operation methods, the status of hormone receptors and HER2, and clinical outcomes were collected. RESULTS: All cases were female patients diagnosed at median age of 50 years. …”
Publicado 2022
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57724por Dong, Menghao, Shan, Benjie, Han, Xinghua, Zhao, Xiaotian, Wang, Fufeng, Zhu, Liuqing, Ou, Qiuxiang, Ma, Xiaopeng, Pan, Yueyin“…Patients received epirubicin and cyclophosphamide for 4 cycles, followed by another 4-cycle docetaxel, and human epidermal growth factor receptor (HER2) positive patients were additionally treated with herceptin when using docetaxel (EC-T(H)). …”
Publicado 2022
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57725por Seppich, Nicolas, Tacca, Nicholas, Chao, Kuo-Yi, Akim, Milan, Hidalgo-Carvajal, Diego, Pozo Fortunić, Edmundo, Tödtheide, Alexander, Kühn, Johannes, Haddadin, Sami“…The device was designed in collaboration with the prosthesis user (pilot), addressing her needs for the competition and aiming for functionality. …”
Publicado 2022
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57726por Zimmermann, Karin, Marfurt-Russenberger, Katrin, Cignacco, Eva, Bergstraesser, Eva“…BACKGROUND: Paediatric Palliative Care (PPC) focuses on ensuring the best possible quality of life for the child and his/her family by extending beyond the physical domain into psychosocial and spiritual wellbeing. …”
Publicado 2022
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57727por Hamel, C C, Vart, P, Vandenbussche, F P H A, Braat, D D M, Snijders, M P L M, Coppus, S F P J“…WIDER IMPLICATIONS OF THE FINDINGS: We developed a prediction model, aimed to improve and personalize counselling for medical treatment of EPL by providing a woman with her individual chance of complete evacuation. STUDY FUNDING/COMPETING INTEREST(S): The Triple M Trial, upon which this secondary analysis was performed, was funded by the Healthcare Insurers Innovation Foundation (project number 3080 B15-191). …”
Publicado 2022
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57728por Madera, Santiago, Izzo, Franco, Chervo, María F., Dupont, Agustina, Chiauzzi, Violeta A., Bruni, Sofia, Petrillo, Ezequiel, Merin, Sharon S., De Martino, Mara, Montero, Diego, Levit, Claudio, Lebersztein, Gabriel, Anfuso, Fabiana, Roldán Deamicis, Agustina, Mercogliano, María F., Proietti, Cecilia J., Schillaci, Roxana, Elizalde, Patricia V., Cordo Russo, Rosalía I.“…Triple-negative breast cancer (TNBC) is clinically defined by the absence of estrogen and progesterone receptors and the lack of membrane overexpression or gene amplification of receptor tyrosine kinase ErbB-2/HER2. Due to TNBC heterogeneity, clinical biomarkers and targeted therapies for this disease remain elusive. …”
Publicado 2022
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57729“…Additionally, high yields (Y((H2/formate))) of 0.86 mol mol(−1) and a hydrogen evolution rate (HER) of 999 mmol L(−1) h(−1) were observed. Finally, stirred-tank bioreactor experiments demonstrated the upscaling feasibility of the applied whole cell system and indicated the importance of pH control for the reaction of formate-driven H(2) production. …”
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57730por Datta, Jharna, Willingham, Natalie, Manouchehri, Jasmine M., Schnell, Patrick, Sheth, Mirisha, David, Joel J., Kassem, Mahmoud, Wilson, Tyler A., Radomska, Hanna S., Coss, Christopher C., Bennett, Chad E., Ganju, Ramesh K., Sardesai, Sagar D., Lustberg, Maryam, Ramaswamy, Bhuvaneswari, Stover, Daniel G., Cherian, Mathew A.“…Lastly, ESR2 (ERβ gene) expression was negatively correlated with ESR1 (ERα gene) and CCND1 RNA expression in human metastatic ERα+/HER2- breast cancer samples. CONCLUSION: Our results demonstrate that highly selective ERβ agonists attenuate the viability of ERα+ breast cancer cell lines in vitro and suggest that this therapeutic strategy merits further evaluation for ERα+ breast cancer.…”
Publicado 2022
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57731“…Interestingly, we could find no predisposing factors such as pelvic abnormalities during surgery. Nevertheless, as her postoperative detailed physical examination revealed skin hyperextensibility, joint laxity, pelvic organ prolapse, and trivial exophthalmos, connective tissue disorders, mainly Ehlers–Danlos syndrome, were suspected. …”
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57732por Lei, Yu, Liu, Caiyang, Wan, Xiu, Yang, Yanhui, Yao, Yi, Luo, Lei, Huang, Tingyu, Li, Ji“…The patient was followed up for 5 months with no recurrence of tumor and the limb weakness and pain were relieved apparently after the successful comprehensive treatment of her primary tumor. CONCLUSION: Pulmonary LELC is a rare subtype of non-small cell lung cancer seldomly accompanied by PNPS. …”
Publicado 2022
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57733“…Among the mothers staying at home, 35% employed a traditional postpartum carer for her baby; 32% did not room-in with their babies, but only 11% spent less than 6 hours a day with their babies. …”
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57734por Arthuis, Chloé, LeGoff, Juliette, Olivier, Marion, Coutin, Anne-Sophie, Banaskiewicz, Nathalie, Gillard, Philippe, Legendre, Guillaume, Winer, Norbert“…CONCLUSION: The Identikit picture of the woman associated with a poor experience of childbirth shows a nullipara who had a complication during her pregnancy, gave birth after induction of labor, or by cesarean or operative vaginal delivery, with the newborn transferred for pediatric care, and medical management considered unsatisfactory.…”
Publicado 2022
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57735por Vittori, Cecilia, Jeansonne, Duane, Yousefi, Hassan, Faia, Celeste, Lin, Zhen, Reiss, Krzysztof, Peruzzi, Francesca“…BACKGROUND: Triple negative breast cancer (TNBC) is an aggressive subtype of breast cancer characterized by the lack of estrogen receptor, progesterone receptor, and HER2. Our lab previously characterized miR-3189-3p as a microRNA with potent anti-cancer activity against glioblastoma. …”
Publicado 2022
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57736por Yao, Kelin, Zhu, Lvcong, Wang, Liang, Xia, Ruiming, Yang, Jianfeng, Hu, Wenbin, Yu, Zhongqiang“…She was hospitalized again, because CT showed significant enlargement of the right thoracic mass, which caused her obvious symptoms of discomfort. The pathological results of CT-guided biopsy at our hospital confirmed SFTP. …”
Publicado 2022
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57737“…Patient samples (138) and breast cancer cell lines (BCC) reflecting different types of BCa were tested for ERα and ERβ mRNA expression using quantitative real-time PCR, as well as for protein expression of ERα, ERβ1, ERβ2, and ERβ5 isoforms, PR, HER2/neu, Ki-67, CK 5/6, and p53 using immunohistochemistry. …”
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57738por Wang, Jianzheng, He, Yunduan, Zhang, Baiwen, Lv, Huifang, Nie, Caiyun, Chen, Beibei, Xu, Weifeng, Zhao, Jing, Cheng, Xiaojiao, Li, Qingli, Tu, Shuiping, Chen, Xiaobing“…The results showed that gender, age, Human epidermal growth factor receptors 2 (HER2) status, PD-L1 expression, primary tumor site and chemotherapy cycles had no significant effect on PFS. …”
Publicado 2022
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57739“…RESULTS: Within the context of The Cancer Genome Atlas (TCGA) dataset, expression of CD274 mRNA, which encodes programmed death-ligand 1 (PD-L1), was found to be significantly overexpressed in TNBC patients compared to patients with HER2 + or luminal breast cancer (BC). Even within TNBC sub-types, CD274 expression was significantly higher in the immune modulatory subtype (TNBC-IM). …”
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57740por Plowey, Edward D., Bussiere, Thierry, Rajagovindan, Raj, Sebalusky, Jennifer, Hamann, Stefan, von Hehn, Christian, Castrillo-Viguera, Carmen, Sandrock, Alfred, Budd Haeberlein, Samantha, van Dyck, Christopher H., Huttner, Anita“…She passed away in hospice care 4 months after her last dose of aducanumab. The postmortem neuropathologic examination confirmed AD neuropathologic changes. …”
Publicado 2022
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