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58181“…It is common practice that lecturer treat his/her class with “one-size-fits-all” policy and strategy. …”
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58182por Cocorpus, Jenelle, Hager, Megan M, Benchimol, Corinne, Bijol, Vanesa, Salem, Fadi, Punj, Sumit, Castellanos, Laura, Singer, Pamela, Sethna, Christine B, Basalely, Abby“…One year later, the proband was provisionally diagnosed with Alport syndrome after a variant of uncertain significance in the COL4A4 gene was identified following targeted family variant testing of her daughter. Upon review of the medical histories of the proband’s children and niece, all but one had the same variant. …”
Publicado 2022
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58183por Melkam, Mamaru, Demilew, Demeke, Kassew, Tilahun, Fanta, Bruik, Yitayih, Sewbesew, Alemu, Kassahun, Muhammed, Yasin, Getnet, Berhanie, Abetu, Eden, Tarekegn, Gebrekidan Ewnetu, Oumer, Mohammed, Nenko, Goshu“…Suicide ideation and an attempt are thinking or trying to kill oneself that facilitates the act of a person intentionally causing his or her death. Suicide is one of the most serious mental health problems and has a great social impact in the world as it is currently the third leading cause of death for youth. …”
Publicado 2022
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58184por Roques, Marjorie, Spiers, Solène, El Husseini, Mayssa’, Drieu, Didier, Laimou, Dimitra, de Kernier, Nathalie, Mazoyer, Anne-Valérie, Guénolé, Fabian“…CONCLUSIONS: The results of this study may have practical implications for clinicians: (1) a situation of bullying should be sought when an adolescent is seen for unexplained externalized behavioural misconduct; (2) low levels of emotional expression in a bullied adolescent may warn about associated self-harm; (3) a bullied adolescent’s tendency to hide this situation from his or her parents may reflect underlying family-related vulnerability; and (4) the phenomenological analysis showed potential particularities in the assumptive world of these adolescents and suggested that relationality may play a crucial role in their experiences. …”
Publicado 2022
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58185por Chiu, Annie Ting Gee, Wong, Sheila Suet Na, Wong, Naomi Wing Tung, Wong, Wilfred Hing Sang, Tso, Winnie Wan Yee, Fung, Cheuk Wing“…The greater number of symptoms each subject experiences, the worse his/ her PedsQL scores. Subjects displaying hypersalivation and swallowing difficulties had average physical health summary scores of less than 30% compared with subjects without these symptoms. …”
Publicado 2022
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58186por Deben, Christophe, Le Compte, Maxim, Siozopoulou, Vasiliki, Lambrechts, Hilde, Hermans, Christophe, Lau, Ho Wa, Huizing, Manon, Lamote, Kevin, Hendriks, Jeroen M. H., Van Dam, Peter, Pauwels, Patrick, Smits, Evelien L. J., Peeters, Marc, Lardon, Filip“…Finally, the TCGA lung adenocarcinoma (LUAD) database was consulted to study the expression of ACE2 in EGFR- and KRAS-mutant samples and ACE2 expression was correlated with EGFR/HER, RAS, BRAF, ROS1, ALK, and MET mRNA expression. …”
Publicado 2022
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58187por McClellan, Bryan, Gries, Paul, Harlow, Brittany, Tiziani, Stefano, Jolly, Christopher, deGraffenried, Linda“…Upon SRPK2 knockdown and inhibition, we observed a decrease in FASN protein and mRNA stability, respectively, in response to IGF-1 exposure that was specific to triple negative and HER2+ breast cancer cell lines. As we explored further, IGF-1 exposure resulted in an altered localization of eGFP expressed SRSF-1, pEGFP-SRSF-1 that was rescued upon both SRPK2 knockdown and mTORC1 inhibition. …”
Publicado 2022
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58188por Church, Candice, Pulliam, Thomas, Longino, Natalie, Park, Song Y, Smythe, Kimberly S, Makarov, Vladimir, Riaz, Nadeem, Jing, Lichen, Amezquita, Robert, Campbell, Jean S, Gottardo, Raphael, Pierce, Robert H, Choi, Jaehyuk, Chan, Timothy A, Koelle, David M, Nghiem, Paul“…Prior studies have characterized tumor-specific T cell responses to MCPyV, which have typically been CD8, but little is known about the T cell response to UV-induced neoantigens. METHODS: A patient in her mid-50s with virus-negative (VN) MCC developed large liver metastases after a brief initial response to chemotherapy. …”
Publicado 2022
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58189por Buscail, Etienne, Muscari, Fabrice, Hostalrich, Aurélien, Bolzinger, Manon, Malavaud, Sandra, Minville, Vincent, Martin, Charlotte, Delhoste, Magali, Houze-Cerfon, Charles Henri, Buscail, Simon, Bastiani, Bruno, Roumiguié, Mathieu, Weyl, Ariane, Carrère, Nicolas, Abbo, Olivier“…The theoretical teaching was broken down according to the students' future tasks and each speaker was a specialist in his or her field of expertise. The results of the questionnaires showed a desire on the part of the students to increase the time spent on practical workshops and theoretical forensic teaching. …”
Publicado 2022
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58190por Perumalla, Sowjanya, Singh, Gagandeep, Xess, Immaculata, Gaurav, Sudesh, Sachdev, Janya, Kabra, S K“…Pleural tap fluid flagged positive in Bactec and C. neoformans grown on subculture. Her condition worsened with septic shock and succumbed to the disease before any treatment could be initiated. …”
Publicado 2022
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58191por Sigera, Liyanage Shamithra Madhumali, Rosa, O.K.D.S.T, Malkanthi, M.A, Jayasekera, P.I, Patabendige, C.G.U.A, Kirirhena, K.D.R.A.“…She was clinically improving however, refractory hypokalemia along with hypernatremia interrupted her antifungal therapy resulting return of severe symptoms. …”
Publicado 2022
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58192“…DESCRIPTION/METHOD: 51 year old woman with no significant past medical history was referred by her General Practicioner with 6-week history of pain and stiffness in hands, arms and legs. …”
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58193por Tapsoba, Jean de Dieu, Cover, Jane, Obong’o, Christopher, Brady, Martha, Cressey, Tim R., Mori, Kira, Okomo, Gordon, Kariithi, Edward, Obanda, Rael, Oluoch-Madiang, Daniel, Chen, Ying Qing, Drain, Paul, Duerr, Ann“…Perception of being at moderate-to-high risk for HIV if not taking PrEP was associated with persistence (adjusted odds ratio, 10.17 [95% CI 5.14 to 20.13], p < 0.001) in a model accounting for county of residence and variables that had p-value <0.1 in unadjusted analysis (age, being in school, initiated PrEP 2 to 3 months before the first interview, still active in DREAMS, having children, having multiple sex partners, partner aware of PrEP use, partner very supportive of PrEP use, partner has other partners, AGYW believes that a partner puts her at risk, male condom use, injectable contraceptive use, and implant contraceptive use). …”
Publicado 2022
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58194por Tahita, Marc Christian, Sondo, Paul, Kabore, Berenger, Ilboudo, Hamidou, Rouamba, Toussaint, Sanou, Hyacinthe, Ouédraogo, Kadija, Compaoré, Adélaïde, Lompo, Palpouguini, Ouedraogo, Florence, Sawadogo, Seydou, Derra, Karim, Sawadogo, Yabré Edmond, Somé, Athanase M., Nana, Macaire, Sorgho, Hermann, Traore-Coulibaly, Maminata, Bassat, Quique, Tinto, Halidou“…BACKGROUND: Malaria infection during pregnancy (MIP) is not only deleterious to the woman, but it also puts her fetus at increased risk of adverse outcomes, such as preterm delivery, low birth weight, and intrauterine growth retardation. …”
Publicado 2022
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58195por Sori, Demisew Amenu, Bretones, Stephan, Mellier, Georges, de Rochambeau, Bertrand“…Data were collected from the patient’s chart, and logbooks, which were filled up from entry till her discharge. A Simplified POPQ(S-POPQ) was used to stage the prolapse at admission, at discharge, and three months follow-ups. …”
Publicado 2022
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58196“…Subtype-specific analyses showed similar associations with ER+ expressing subtypes: luminal A-like BC, luminal B-like BC and luminal B/HER2-negative-like BC. CONCLUSIONS: TT, BT, DHEAS and estradiol increase the risk of ER+ type BCs similar to observational studies. …”
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58197por Di Benedetto, Carolina, Oh, Justin, Choudhery, Zainab, Shi, Weiquan, Valdes, Gilmer, Betancur, Paola“…Through in-vitro pharmacological super-enhancer disruption assays, we confirmed that super-enhancers upregulate NSMCE2 and MAL2 transcriptionally, and, through bioinformatics, we found that high levels of NSMCE2 strongly associate with patients’ poor response to chemotherapy, especially for patients diagnosed with aggressive triple negative and HER2 positive tumor types. Finally, we showed that decreasing NSMCE2 gene expression increases breast cancer cells’ sensitivity to chemotherapy treatment. …”
Publicado 2022
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58198por Giovannini, Silvia, Iacovelli, Chiara, Brau, Fabrizio, Loreti, Claudia, Fusco, Augusto, Caliandro, Pietro, Biscotti, Lorenzo, Padua, Luca, Bernabei, Roberto, Castelli, Letizia“…BACKGROUND: Stroke, the incidence of which increases with age, has a negative impact on motor and cognitive performance, quality of life, and the independence of the person and his or her family, leading to a number of direct and indirect costs. …”
Publicado 2022
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58199por Qian, Xiaoyan, Xiu, Meng, Li, Qing, Wang, Jiayu, Fan, Ying, Luo, Yang, Cai, Ruigang, Li, Qiao, Chen, Shanshan, Yuan, Peng, Ma, Fei, Xu, Binghe, Zhang, Pin“…The predominant tumor subtypes were human epidermal growth factor receptor type 2 (HER2)-positive breast cancer (49.0%) and triple-negative breast cancer (TNBC) (30.8%). …”
Publicado 2022
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58200por Cyrta, Joanna, Benoist, Camille, Masliah-Planchon, Julien, Vieira, Andre F., Pierron, Gaëlle, Fuhrmann, Laetitia, Richardot, Camille, Caly, Martial, Leclere, Renaud, Mariani, Odette, Da Maia, Elisabeth, Larousserie, Frédérique, Féron, Jean Guillaume, Carton, Matthieu, Renault, Victor, Bidard, François-Clément, Vincent-Salomon, Anne“…All OGC-IC NST and OGC-Mixed cases were ER+ HER2− tumors (most being luminal A based on transcriptomic subtyping, when available), while all OGC-MC were triple-negative. …”
Publicado 2022
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