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58541por Panou, Evdoxia, Nikolaou, Vasiliki, Kaliampou, Stella, Sidiropoulou, Polytimi, Stratigos, Alexander“…A flare of LyP was confirmed from the pathology, which correlated to her clinical picture. DISCUSSION: These cases raise the question of whether and via which pathways the vaccine might induce disease exacerbation of both MF and LyP. …”
Publicado 2021
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58542por Cazzaniga, M. E., Vallini, I., Montagna, E., Amoroso, D., Berardi, R., Butera, A., Cagossi, K., Cavanna, L., Ciccarese, M., Cinieri, S., Cretella, E., De Conciliis, E., Febbraro, A., Ferraù, F., Ferzi, A., Baldelli, A., Fontana, A., Gambaro, A. R., Garrone, O., Gebbia, V., Generali, D., Gianni, L., Giovanardi, F., Grassadonia, A., Leonardi, V., Marchetti, P., Sarti, S., Musolino, A., Nicolini, M., Putzu, C., Riccardi, F., Santini, D., Saracchini, S., Sarobba, M. G., Schintu, M. G., Scognamiglio, G., Spadaro, P., Taverniti, C., Toniolo, D., Tralongo, P., Turletti, A., Valenza, R., Valerio, M. R., Vici, P., Di Mauro, P., Cogliati, V., Capici, S., Clivio, L., Torri, V.“…PURPOSE: Triple-negative breast cancer (TNBC) represents a subtype of breast cancer which lacks the expression of oestrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor-2 (HER2): TNBC accounts for approximately 20% of newly diagnosed breast cancers and is associated with younger age at diagnosis, greater recurrence risk and shorter survival time. …”
Publicado 2021
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58543por Kim, Hugh Andrew Jinwook, Shaikh, Mushfiq Hassan, Lee, Mark, Zeng, Peter Y. F., Sorgini, Alana, Akintola, Temitope, Deng, Xiaoxiao, Jarycki, Laura, Khan, Halema, MacNeil, Danielle, Khan, Mohammed Imran, Mendez, Adrian, Yoo, John, Fung, Kevin, Lang, Pencilla, Palma, David A., Patel, Krupal, Mymryk, Joe S., Barrett, John W., Boutros, Paul C., Morris, Luc G. T., Nichols, Anthony C.“…In the tumor microenvironment, 3p arm lost tumors had low immune cell infiltration (FDR < 0.1) and elevated hypoxia (FDR < 0.1). 3p arm lost tumors had lower abundance of proteins phospho-HER3 and ANXA1, and higher abundance of miRNAs hsa-miR-548k and hsa-miR-421, which were all associated with survival. …”
Publicado 2021
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58544por Dhariwal, Raman, Hiebert, Colin W., Sorrells, Mark E., Spaner, Dean, Graf, Robert J., Singh, Jaswinder, Randhawa, Harpinder S.Enlace del recurso
Publicado 2021
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58545por Rweyemamu, Linus P., Akan, Gokce, Adolf, Ismael C., Magorosa, Erick P., Mosha, Innocent J., Dharsee, Nazima, Namkinga, Lucy A., Lyantagaye, Sylvester L., Nateri, Abdolrahman S., Atalar, Fatmahan“…We observed that post-menopausal status was more prevalent in luminal-A subtype, while compared to luminal-A subtype, luminal-B and HER-2 enriched subtypes were less likely to be found in post-menopausal women (OR: 0.21, 95%CI 0.10–0.41, p = 0.001; OR: 0.39, 95%CI 0.17–0.89, p = 0.026, respectively). …”
Publicado 2021
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58546por Iseas, Soledad, Sendoya, Juan M., Robbio, Juan, Coraglio, Mariana, Kujaruk, Mirta, Mikolaitis, Vanesa, Rizzolo, Mariana, Cabanne, Ana, Ruiz, Gonzalo, Salanova, Rubén, Gualdrini, Ubaldo, Méndez, Guillermo, Antelo, Marina, Carballido, Marcela, Rotondaro, Cecilia, Viglino, Julieta, Eleta, Martín, Di Sibio, Alejandro, Podhajcer, Osvaldo L., Roca, Enrique, Llera, Andrea S., Golubicki, Mariano, Abba, Martín Carlos“…Here, we performed an integrated characterization of the predictive and prognostic role of clinical features, mismatch-repair deficiency markers, HER2, CDX2, PD-L1 expression, and CD3(−)CD8(+) tumor-infiltrating lymphocytes (TILs) coupled with targeted DNA sequencing of 76 non-metastatic RC patients assigned to total mesorectal excision upfront (TME; n = 15) or neoadjuvant chemo-radiotherapy treatment (nCRT; n = 61) followed by TME. …”
Publicado 2022
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58547por Gurol-Urganci, Ipek, Waite, Lara, Webster, Kirstin, Jardine, Jennifer, Carroll, Fran, Dunn, George, Frémeaux, Alissa, Harris, Tina, Hawdon, Jane, Muller, Patrick, van der Meulen, Jan, Khalil, Asma“…There was some evidence that differences in the rates of preterm birth, emergency cesarean section, and unassisted vaginal birth varied according to the mother’s ethnic background but not according to her socioeconomic background. A key limitation is that multiple comparisons were made, increasing the chance of false-positive results. …”
Publicado 2022
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58548“…She was previously riding a motorcycle, then stopped at the traffic light with left leg stepping on the road. Her left leg was hit from behind by a moving car. …”
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58549por Wang, Weiwei, Zhang, Xindong, Zhu, Laimin, Chen, Yueqin, Dou, Weiqiang, Zhao, Fan, Zhou, Zhe, Sun, Zhanguo“…Luminal B showed decreased D value compared with other subtypes (p < 0.05). The HER-2-positive subtype demonstrated increased ADC values compared with the Luminal B subtype (p < 0.05). …”
Publicado 2022
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58550“…This score was calculated based on the 24 h recall of the mother and her child's consumption of 7 food groups, during the 24 h prior to the survey. …”
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58551por West, Matthew, Sadler, Sean, Charles, James, Hawke, Fiona, Lanting, Sean, Munteanu, Shannon E., Chuter, Vivienne“…GRAPHICAL ABSTRACT: [Image: see text] Artist Jenni McEwen (Bundjalung) lives on Darkinjung Country. The story of her art shows people sitting in yarning circles sharing knowledges but looking outwards to connect with Country too, the Ochre of Wiradjuri Country around Wellington, and the Blue of Darkinjung Country around Central Coast. …”
Publicado 2022
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58552por Juncker, Hannah G., Mulleners, Sien J., Ruhé, Eliza J.M., Coenen, Esmée R.M., Bakker, Sjors, van Doesburg, Maritt, Harinck, Jolinda E., Rood, Romee D., Bouhuijs, Joey H., Oomen, Melissa, de Groot, Prof. Christianne J.M., Pajkrt, Prof. Dasja, Korosi, Aniko, van Goudoever, Prof. Johannes B., van Gils, Marit J., van Keulen, Britt J.“…Therefore, vaccination with mRNA-based vaccines, preferably with the mRNA-1273 vaccine, might not only provide better immunological protection for the mother but also for her breastfed infant. FUNDING: Stichting Steun Emma Kinderziekenhuis and the Amsterdam Infection and Immunity Institute (grant 24175).…”
Publicado 2022
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58553por de Almeida, Liz Maria, Cortés, Sandra, Vilensky, Marta, Valenzuela, Olivia, Cortes-Sanabria, Laura, de Souza, Mirian, Barbeito, Rafael Alonso, Abdelhay, Eliana, Artagaveytia, Nora, Daneri-Navarro, Adrian, Llera, Andrea S., Müller, Bettina, Podhajcer, Osvaldo L., Velazquez, Carlos, Alcoba, Elsa, Alonso, Isabel, Bravo, Alicia I., Camejo, Natalia, Carraro, Dirce Maria, Castro, Mónica, Cataldi, Sandra, Cayota, Alfonso, Cerda, Mauricio, Colombo, Alicia, Crocamo, Susanne, Del Toro-Arreola, Alicia, Delgadillo-Cristerna, Raul, Delgado, Lucia, Breitenbach, Marisa Dreyer, Fernández, Elmer, Fernández, Jorge, Fernández, Wanda, Franco-Topete, Ramon A., Gaete, Fancy, Gómez, Jorge, Gonzalez-Ramirez, Leivy P., Guerrero, Marisol, Gutierrez-Rubio, Susan A., Jalfin, Beatriz, Lopez-Vazquez, Alejandra, Loria, Dora, Míguez, Silvia, Moran-Mendoza, Andres de J., Morgan-Villela, Gilberto, Mussetti, Carina, Nagai, Maria Aparecida, Oceguera-Villanueva, Antonio, Reis, Rui M., Retamales, Javier, Rodriguez, Robinson, Rosales, Cristina, Salas-Gonzalez, Efrain, Segovia, Laura, Sendoya, Juan M., Silva-Garcia, Aida A., Viña, Stella, Zagame, Livia, Jones, Beth, Szklo, Moysés“…Multivariable-adjusted death hazard differences were found for women living in Argentina (2.27), Chile (1.95), and Uruguay (2.42) compared with Mexican women, for older (≥60 years) (1.84) compared with younger (≤40 years) women, for basal-like subtype (5.8), luminal B (2.43), and HER2-enriched (2.52) compared with luminal A subtype, and for tumor clinical stages IIB (1.91), IIIA (3.54), and IIIB (3.94) compared with stage IIA women. …”
Publicado 2022
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58554por Eser, Kadir, Önder, Arif Hakan, Sezer, Emel, Çil, Timuçin, İnal, Ali, Öztürk, Banu, Erçolak, Vehbi, Duman, Berna Bozkurt, Çelik, Halil, Köşeci, Tolga, Kesen, Oğuzhan“…PATIENTS AND METHODS: We enrolled hormone receptor-positive, HER2-negative mBC patients treated with endocrine treatment (letrozole or fulvestrant) combined palbociclib or ribociclib alone or with PPI accompanying our observational study. …”
Publicado 2022
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58555por Rigiracciolo, Damiano Cosimo, Nohata, Nijiro, Lappano, Rosamaria, Cirillo, Francesca, Talia, Marianna, Adame-Garcia, Sendi Rafael, Arang, Nadia, Lubrano, Simone, De Francesco, Ernestina Marianna, Belfiore, Antonino, Gutkind, J. Silvio, Maggiolini, Marcello“…RESULTS: We found a remarkable high expression of S100A8 and S100A9 in BC, particularly in HER2-positive and TNBC, with the latter associated to worst clinical outcomes. …”
Publicado 2022
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58556por Wolf, Jule, Kurz, Steffen, Rothe, Thomas, Serpa, Marco, Scholber, Jutta, Erbes, Thalia, Gkika, Eleni, Baltas, Dimos, Verma, Vivek, Krug, David, Juhasz-Böss, Ingolf, Grosu, Anca-Ligia, Nicolay, Nils H., Sprave, Tanja“…Neoadjuvant or adjuvant systemic therapy was administered depending on hormone receptor and HER2-status. CT scans in FB and DIBH position with individual coaching and determination of the breathing amplitude during the radiation planning CT were performed for all patients. …”
Publicado 2022
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58557por Fang, Yutong, Liu, Junpeng, Zhang, Qunchen, She, Chuanghong, Zheng, Rongji, Zhang, Rendong, Chen, Zexiao, Chen, Chunfa, Wu, Jundong“…RESULTS: VDAC1 expression was remarkably elevated in BC (p < 0.001), and high expression of VDAC1 was associated with the positive expression of ER (p = 0.004), PR (p = 0.033), and HER2 (p = 0.001). ROC analysis suggested that VDAC1 had diagnosed value in BC. …”
Publicado 2022
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58558por Chuan, Jiacheng, Belov, Anatoly, Cloutier, Michel, Li, Xiang, Khan, Izhar U. H., Chen, WenEnlace del recurso
Publicado 2022
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58559por van Herpen-Meeuwissen, Loes Johanna Maria, Bekker, Charlotte Linde, Cornelissen, Nicky, Maat, Barbara, van Onzenoort, Hendrikus Antonius Walterus, van den Bemt, Bartholemeus Johannes Fredericus“…The most important requirements for SAM by patients were, ‘I want to be informed before my hospitalisation that I have to bring my own medication’ (80% agreed) and ‘Healthcare professionals must assess per patient whether the patient is able to manage and use his or her own medication’ (74% agreed). Conclusion: Most patients mentioned many advantages and had positive views on SAM. …”
Publicado 2022
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58560por Yang, Huan, Ouyang, Qu-Chang, Yan, Min, Wang, Xiao-Jia, Hu, Xi-Chun, Jiang, Ze-Fei, Huang, Tao, Tong, Zhong-Sheng, Wang, Shu-Sen, Yin, Yong-Mei, Li, Hui, Yang, Run-Xiang, Yang, Hua-Wei, Teng, Yue-E, Sun, Tao, Cai, Li, Li, Hong-Yuan, Ouyang, Xue-Nong, He, Jian-Jun, Liu, Xin-Lan, Yang, Shun-E, Fan, Jin-Hu, Wang, Jia-Yu, Qiao, You-Lin, Xu, Bing-He“…Age at initial diagnosis was shown to be significantly related to hormone receptor status, human epidermal growth factor receptor 2 (HER2) status, molecular subtypes, and the number of lymph node metastasis (all P<0.05). …”
Publicado 2022
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