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58601“…To oversee this risk, the cumulative effective dose (CED) received by a patient from imaging procedures over his or her life is important. In this paper, the authors, on behalf of EuroSafe Imaging, report on a survey carried out in Europe that aims to estimate the proportion of patients that undergo CT examinations and are exposed to a CED of more than 100 mSv. …”
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58602por Fu, Fangmeng, Yu, Liuwen, Zeng, Bangwei, Chen, Minyan, Guo, Wenhui, Chen, Lili, Lin, Yuxiang, Hou, Jialin, Li, Jing, Li, Yan, Li, Shengmei, Chen, Xiaobin, Zhang, Wenzhe, Jin, Xuan, Cai, Weifeng, Zhang, Kun, Chen, Hanxi, Qiu, Yibin, Nie, Qian, Wang, Chuan, Jacobs, Lisa“…All patients included were diagnosed with stage I to stage III hormone receptor–positive, human epidermal growth factor receptor-2 (ERBB2; formerly HER2)–negative invasive breast cancer and underwent AHT without chemotherapy. …”
Publicado 2022
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58603por Bowdridge, Elizabeth C., DeVallance, Evan, Garner, Krista L., Griffith, Julie A., Schafner, Kallie, Seaman, Madison, Engels, Kevin J., Wix, Kimberley, Batchelor, Thomas P., Goldsmith, William T., Hussain, Salik, Nurkiewicz, Timothy R.“…We hypothesized that maternal nano-TiO(2) inhalation exposure during gestation in the F0 dams would result in upregulated H(2)O(2) production in the F0 dams as well as her F1 offspring. Additionally, this toxicological insult would result in gestational vascular dysfunction in the F1 dams yielding smaller F2 generation pups. …”
Publicado 2022
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58604“…The language policy has enabled her to benefit from lower costs of education, science and technology. …”
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58605por Bergeson, Joette Gdovin, Worley, Karen, Louder, Anthony, Ward, Melea, Graham, John“…Failure of a member to take medication deemed necessary by his or her physician could translate to inadequate control of the diabetic condition and result in an excess of resource utilization and costs for treating the disease and associated comorbidities. …”
Publicado 2013
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58606“…However, after the subsequent identification of ADA2-deficiency vasculitis, the patient underwent genetic screening which identified a compound heterozygosity for two novel ADA2 mutations (c6634_636, delTTC (p.Phe212del) and c.1225C>T (p.Pro409Ser)). Her mother was as a carrier. She was started on adalimumab injections to which she had a good clinical response with improved cutaneous disease and no further neurological symptoms. …”
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58607por Freisleben, Moritz, Petzel, Anja, Jülicher, Anne, Jonas, Anna, Betzler, Janina, Choly, Natalia, Pashayeva, Esmira, Porthun, Jan, Welcker, Thomas, Schneider, Viola, Kaufmann, Andreas M., Schneider, Achim“…We started with a feasibility study : 303 patients diagnosed with HSIL/AIS of the uterine cervix and her colposcopist answered an electronic questionnaire with respect to loop excision under LA. …”
Publicado 2023
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58608“…D.’s wife called the clinic to report that her husband’s diarrhea continued despite the use of tincture of opium and that it was associated with hematochezia. …”
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58609por Ezebialu, Ifeanyichukwu U, Eke, Ahizechukwu C, Eleje, George U, Nwachukwu, Chukwuemeka E“…The need for induction of labour may arise due to a problem in the mother, her fetus or both, and the procedure may be carried out at or before term. …”
Publicado 2015
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58610Publicado 2006“…Der normale Replikationsmechanismus linearer DNA-Moleküle führt in jedem Replikationszyklus zu einer Verkürzung der DNADoppelhelix von den Enden her, da die RNA-Primer am Ende der DNA zwar entfernt, aber nicht durch DNASequenzen ersetzt werden können. …”
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58611por Selman-Geara, Antonio, Benitez-Camporro, Antonio, Defillo-Guerrero, Guillermo, Ibrahim, Ammar, Redondo, Cytopathologist, Yasmin, Rodriguez, L, Selman-Fermin, Antoine, Selman-Fermin, Anyel I“…Clinical findings: (03/13/2019) Height 62”, Weight 142 lbs, Temperature 36.2 Celsius, BP 90/60 mmHg, RR 16 rpm, HR 60 bpm, on her neck no adenopathies or thyroid changes. Occasional coughing. …”
Publicado 2020
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58612por Dong, Lingli, Huang, Anbin, Zhang, Shengtao, Yu, Yikai, li, Shouxin, Shen, Lingxun, Yang, Huiqin, Li, Huiling, Tu, Shenghao, Xiao, Fei“…The physician can then do an online consultation and renew prescriptions on the basis of real-time data from his or her patients. We aimed to establish the feasibility and effects of SSDM in maintaining effective interactions between patients and physicians in Hubei province during the COVID-19 epidemic period. …”
Publicado 2020
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58613por Li, Jinming, Huo, Xingfa, Zhao, Fuxing, Ren, Dengfeng, Ahmad, Raees, Yuan, Xinyue, Du, Feng, Zhao, Jiuda“…IMPORTANCE: One of the most recent treatment regimens used for hormone receptor (HR)–positive, ERBB2 (formerly HER2)–negative metastatic breast cancer is treatment with the cyclin-dependent kinases 4 and 6 (CDK4/6) inhibitors and endocrine therapy (ET). …”
Publicado 2020
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58614“…Statistical analysis indicated that histological grade, N stage, and HER2 overexpression subtype were associated with ENE. …”
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58615Publicado 2021“…Auch eine Zusatzweiterbildung oder eine Zusatzbezeichnung kann einen qualifikationsbezogenen Sonderbedarf begründen, wenn sie den in 37 Abs. 1 BedarfsplanungsRL genannten Qualifikationen vom zeitlichen und qualitativen Umfang her gleichsteht. 4. Bei der Bedarfsprüfung sind nur reale, nicht dagegen potenzielle Versorgungsangebote zu berücksichtigen, die tatsächlich nicht zur Verfügung stehen, weil Leistungserbringer nicht zur Erbringung weiterer Leistungen bereit oder tatsächlich nicht in der Lage sind. 5. …”
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58616por Lapinski, Jillian, Ngo, Sandra Hoang, Lee, Pui Y, Walkovich, Kelly J., Hannibal, Mark, DeMeyer, Lauren, Mohan, Smriti, Michniacki, Thomas F.“…She required escalation to high dose methylprednisolone (30mg/kg), rituximab 375 mg/m (2)/weekly x4 doses, and concurrent romiplostim (2 doses) for control of thrombocytopenia and bleeding manifestations. Her rheumatologic symptoms subsided with initiation of corticosteroids, and she has subsequently completed a prolonged corticosteroid taper. …”
Publicado 2021
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58617por Mavaddat, Nasim, Dorling, Leila, Carvalho, Sara, Allen, Jamie, González-Neira, Anna, Keeman, Renske, Bolla, Manjeet K., Dennis, Joe, Wang, Qin, Ahearn, Thomas U., Andrulis, Irene L., Beckmann, Matthias W., Behrens, Sabine, Benitez, Javier, Bermisheva, Marina, Blomqvist, Carl, Bogdanova, Natalia V., Bojesen, Stig E., Briceno, Ignacio, Brüning, Thomas, Camp, Nicola J., Campbell, Archie, Castelao, Jose E., Chang-Claude, Jenny, Chanock, Stephen J., Chenevix-Trench, Georgia, Christiansen, Hans, Czene, Kamila, Dörk, Thilo, Eriksson, Mikael, Evans, D. Gareth, Fasching, Peter A., Figueroa, Jonine D., Flyger, Henrik, Gabrielson, Marike, Gago-Dominguez, Manuela, Geisler, Jürgen, Giles, Graham G., Guénel, Pascal, Hadjisavvas, Andreas, Hahnen, Eric, Hall, Per, Hamann, Ute, Hartikainen, Jaana M., Hartman, Mikael, Hoppe, Reiner, Howell, Anthony, Jakubowska, Anna, Jung, Audrey, Khusnutdinova, Elza K., Kristensen, Vessela N., Li, Jingmei, Lim, Swee Ho, Lindblom, Annika, Loizidou, Maria A., Lophatananon, Artitaya, Lubiński, Jan, Madsen, Michael J., Mannermaa, Arto, Manoochehri, Mehdi, Margolin, Sara, Mavroudis, Dimitrios, Milne, Roger L., Mohd Taib, Nur Aishah, Morra, Anna, Muir, Kenneth, Obi, Nadia, Osorio, Ana, Park-Simon, Tjoung-Won, Peterlongo, Paolo, Radice, Paolo, Saloustros, Emmanouil, Sawyer, Elinor J., Schmutzler, Rita K., Shah, Mitul, Sim, Xueling, Southey, Melissa C., Thorne, Heather, Tomlinson, Ian, Torres, Diana, Truong, Thérèse, Yip, Cheng Har, Spurdle, Amanda B., Vreeswijk, Maaike P.G., Dunning, Alison M., García-Closas, Montserrat, Pharoah, Paul D.P., Kvist, Anders, Muranen, Taru A., Nevanlinna, Heli, Teo, Soo Hwang, Devilee, Peter, Schmidt, Marjanka K., Easton, Douglas F.“…MAIN OUTCOMES AND MEASURES: The intrinsic-like BC subtypes as defined by estrogen receptor, progesterone receptor, and ERBB2 (formerly known as HER2) status, and tumor grade; morphology; size; stage; lymph node involvement; subtype-specific odds ratios (ORs) for carrying protein-truncating variants and pathogenic missense variants in the 9 BC susceptibility genes. …”
Publicado 2022
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58618“…The film describes the story that when the earthquake occurred, the family was buried underground, and the mother struggled to make the decision that two children can only save one child in order to save her children. The positive emotion inducing material selects a 6-minute film clip of “people in the middle of nowhere”, which tells a series of funny things that happen when two men live in a small hotel together. …”
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58619por Rashid, Md Harunur“…Abbreviations: ADA Anti-drug antibody; ADCC Antibody-dependent cellular cytotoxicity; ADCP Antibody-dependent cellular phagocytosis; ADC Antibody-drug conjugate; aFc Aglycosylated Fc; AMD Age-related macular degeneration aTTP Acquired thrombotic thrombocytopenic purpura; BCMA B-cell maturation antigen; BLA Biologics license application; BsAb Bispecific antibody; C1q Complement protein C1q; CDC Complement-dependent cytotoxicity; CDCC Complement-dependent cellular cytotoxicity; CDCP Complement-dependent cellular phagocytosis; CEX Cation exchange chromatography; CFPS Cell-free protein expression; CHO Chinese Hamster Ovary; CH1-3 Constant heavy chain 1-3; CL Constant light chain; DLBCL Diffuse large B-cell lymphoma; DAR Drug antibody ratio; DC Dendritic cell; dsFv Disulfide-stabilized Fv; EU European Union; EGFR Epidermal growth factor receptor; E. coli Escherichia coli; EpCAM Epithelial cell adhesion molecule; Fab Fragment antigen binding; FACS Fluorescence activated cell sorting; Fc Fragment crystallizable; FcRn Neonatal Fc receptor; FcɣRs Fc gamma receptors; FDA Food and Drug Administration; FL-IgG Full-length immunoglobulin; Fv Fragment variable; FolRαa Folate receptor alpha; gFc Glycosylated Fc; GM-CSF Granulocyte macrophage-colony stimulating factor; GPx7 Human peroxidase 7; HCL Hairy cell leukemia; HIV Human immunodeficiency virusl; HER2 Human epidermal growth factor receptor 2; HGF Hepatocyte growth factor; HIC Hydrophobic interaction chromatography; HLA Human leukocyte antigen; IBs Inclusion bodies; IgG1-4 Immunoglobulin 1-4; IP Intraperitoneal; ITC Isothermal titration calorimetry; ITP Immune thrombocytopenia; IV Intravenous; kDa Kilodalton; KiH Knob-into-Hole; mAb Monoclonal antibody; MAC Membrane-attack complex; mCRC Metastatic colorectal cancer; MM Multipl myeloma; MOA Mechanism of action; MS Mass spectrometry; MUC1 Mucin 1; MG Myasthenia gravis; NB Nanobody; NK Natural killer; nsAA Nonstandard amino acid; NSCLC Non-small cell lung cancer; P. aeruginosa Pseudomonas aeruginosa; PD-1 Programmed cell death 1; PD-L1 Programmed cell death-ligand 1; PDI Protein disulfide isomerase; PECS Periplasmic expression cytometric screening; PK Pharmacokinetics; P. pastoris Pichia pastoris; PTM Post-translational modification; Rg Radius of gyration; RA Rheumatoid arthritis; RT-PCR Reverse transcription polymerase chain reaction; SAXS Small angle X-ray scattering; scF Single chain Fv; SCLC Small cell lung cancer; SDS-PAGE Sodium dodecyl sulfate–polyacrylamide gel electrophoresis; SEC Size exclusion chromatography; SEED Strand-exchange engineered domain; sRNA Small regulatory RNA; SRP Signal recognition particle; T1/2 Half-life; Tagg Aggregation temperature; TCR T cell receptor; TDB T cell-dependent bispecific; TF Tissue factor; TIR Translation initiation region; Tm Melting temperature; TNBC Triple-negative breast cancer; TNF Tumor necrosis factor; TPO Thrombopoietin; VEGF Vascular endothelial growth factor; vH Variable heavy chain; vL Variable light chain; vWF von Willebrand factor; WT Wild type…”
Publicado 2022
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58620“…Focus not on “fixing” pain Use of breathing/distraction techniques; encouraged weight-bearing, movement, desensitisation and mobility DISCUSSION/RESULTS: CASE STUDY INTERVENTION OUTCOMES [after one x 2 hour therapy session]: Touching own leg Noticed colour change in L leg/foot Actively started to move toes Took partial weight through L heel using crutches Negotiated stairs Reported to feel “confident” enough to be able to work on strategies at home Trialled wearing a soft shoe on her L foot Learnt breathing techniques and was able to use distraction Able to set some functional goals, e.g. school attendance, playing football, seeing friends From our extensive experience, we understand that: Intervention begins with the individual) - “Being healthy is more than just not being ill - it's about our physical, mental and emotional wellbeing” MDT approach is the most successful treatment for CRPS. …”
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