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Mostrando 921 - 940 Resultados de 58,773 Para Buscar '"Her"', tiempo de consulta: 0.41s Limitar resultados
  1. 921
    “…The human epidermal growth factor receptor 3 (HER3) has in recent years been recognized as a key node in the complex signaling network of many different cancers. …”
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    Targeting HER3 using mono- and bispecific antibodies or alternative scaffolds
  2. 922
    “…In gynecologic neoplasms, determination of HER2/neu status has not been well studied as a predictive biomarker in anti-HER2/neu treatment. …”
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    Systematic assessment of HER2/neu in gynecologic neoplasms, an institutional experience
  3. 923
    “…BACKGROUND: Trastuzumab, a humanized monoclonal antibody against the HER2 receptor is currently being used in breast and other tumor types. …”
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    HER2 expression in cervical cancer as a potential therapeutic target
  4. 924
    “…Few data are available on HER2 status in differentiated thyroid cancer (DTC). …”
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    HER2 Analysis in Sporadic Thyroid Cancer of Follicular Cell Origin
  5. 925
    “…Jayson GC et al. remarked in Lancet that nearly 100% of mucinous ovarian cancer cases have Kras mutation as well as a high frequency of Her2 amplification. Using the Abbott PathVysion Her2 DNA Probe Kit and Kras mutant-enriched PCR Kits (FemtoPath®), 21 samples of primary ovarian mucinous cystadenocarcinomas from Taiwanese patients were examined to determine the status of Her2 amplification and Kras mutations. …”
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    The status of Her2 amplification and Kras mutations in mucinous ovarian carcinoma
  6. 926
    “…Among these archaeal genes a homolog to the Sulfolobus spp. HerA protein appears in all of the Thermus spp. strains so far sequenced (HepA). …”
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    Role of Archaeal HerA Protein in the Biology of the Bacterium Thermus thermophilus
  7. 927
    “…BACKGROUND: Human epidermal growth factor receptor 2 (HER2) is related to the pathogenesis and poor outcome of numerous types of carcinomas, including gastric carcinoma. …”
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    HER2 Status and Its Heterogeneity in Gastric Carcinoma of Vietnamese Patient
  8. 928
    por Liu, Xianqiang, Zhang, Nan, Shi, Huan
    Publicado 2017
    “…However, HER2 CAR T cells pose a risk of lethal toxicity including cytokine release syndrome from “on-target, off-tumor” recognition of HER2. …”
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    Driving better and safer HER2-specific CARs for cancer therapy
  9. 929
    “…The advent of trastuzumab and other human epidermal growth factor receptor 2 (HER2)-directed therapies has revolutionized the treatment of metastatic HER2-positive breast cancer, leading to prolonged survival and appreciable clinical benefit for a substantial subset of patients. …”
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    Metastatic HER2+ Breast Cancer: A Potentially Curable Disease?
  10. 930
    “…However, it is unclear how AR functions in HER2 positive (+) BC. Knockdown of AR with shRNAs and a new generation anti-androgen drug, Enzalutamide, were used to explore the involvement of AR on the growth of HER2 + BC cells (HCC1954 and SKBR3). …”
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    Targeting Androgen Receptor in Treating HER2 Positive Breast Cancer
  11. 931
    por Royce, Melanie, Herold, Karen
    Publicado 2016
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    New Agents for the Management of Advanced HER2-Positive Breast Cancer
  12. 932
    por Connell, Claire M, Doherty, Gary J
    Publicado 2017
    “…HER2 functional activation promotes oncogenesis, leading to the investigation of HER2-directed agents in cancers with HER2 alterations. …”
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    Activating HER2 mutations as emerging targets in multiple solid cancers
  13. 933
    “…RESULTS: The median survival time with Her-2 overexpression in malignant pleural effusions was 2.2 months, whereas cases without overexpression survived, on average, for seven months (p = 0.02). …”
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    Impact of Her-2 Overexpression on Survival of Patients with Metastatic Breast Cancer
  14. 934
    “…HER2 is overexpressed in 20% of invasive breast cancers (BCs) and correlates with a more aggressive disease. …”
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    Predicting the Efficacy of HER2-Targeted Therapies: A Look at the Host
  15. 935
    “…DISCUSSION: There are few pure mucinous carcinomas positive for HER2. Mucinous carcinomas are positive for HER2 account for less than 5% of invasive ductal carcinoma. …”
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    Her-2 positive mucinous carcinoma breast cancer, case report
  16. 936
    “…HER-2 belongs to the human epidermal growth factor receptor (HER) family. …”
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    Structural investigations on mechanism of lapatinib resistance caused by HER-2 mutants
  17. 937
    “…BACKGROUND: HER2 mutation has been found to be an oncogenic driver gene in non-small cell lung cancers(NSCLC) and HER2-directed therapies have shown promising results in this unique population, while little is known about its association with outcomes of chemotherapy. …”
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    Outcomes of Pemetrexed-based chemotherapies in HER2-mutant lung cancers
  18. 938
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    Pityriasis Rosea in a Mother and her Daughter: A Case Report
  19. 939
    “…We further show that EGFR and HER2 are activated through phosphorylation by Src family kinases (SFK). …”
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    EGFR and HER2 Activate Rigidity Sensing Only on Rigid Matrices
  20. 940
    “…Jacqueline du Pré was a British cellist, famous for her masterful interpretations and her passionate style of playing. …”
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    The Sound of Jacqueline du Pré: Revisiting her Medical and Musical History
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