Materias dentro de su búsqueda.
Materias dentro de su búsqueda.
Historia
24
Películas cinematográficas
16
Música popular
13
Novela estadounidense
12
Jazz
10
Música para órgano
7
Crítica e interpretación
6
Música rock
6
Correspondencia
5
Comedy films
4
Condiciones sociales
4
Diarios íntimos
4
Estados Unidos
4
Música
4
Música vocal (Jazz)
4
Novelistas ingleses
4
Arte
3
Aspectos sociales
3
Bailarines
3
Blues (Música)
3
Christmas music
3
Foreign films
3
Historia y crítica
3
Libros falsos
3
Literatura estadounidense
3
Motetes
3
Música de jazz
3
Operas
3
Songs (High voice) with piano
3
Songs (Medium voice) with piano
3
-
941“…The development of human epidermal growth factor 2 (HER2)-directed therapy has resulted in significant improvement in outcomes for patients with early-stage HER2-overexpressing (HER2+) breast cancer. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
942por Swerdlow, Anthony J., Wright, Lauren B., Schoemaker, Minouk J., Jones, Michael E.“…METHODS: In a cohort of 83,451 parous women from the general population of the UK, which collected detailed information on each pregnancy and a wide range of potential confounders, we investigated the associations of length of gestation and birthweight of offspring in a woman’s pregnancies with her breast cancer risk, adjusting for a full range of non-reproductive as well as reproductive risk factors unlike in previous large studies. …”
Publicado 2018
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
943“…For this reason, we wanted to investigate the expression of intra- and extracellular domains of ErbB2/HER2 as well as the level of activated receptor in these tumors. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
944por Rye, Inga H., Trinh, Anne, Sætersdal, Anna B., Nebdal, Daniel, Lingjærde, Ole Christian, Almendro, Vanessa, Polyak, Kornelia, Børresen‐Dale, Anne‐Lise, Helland, Åslaug, Markowetz, Florian, Russnes, Hege G.“…Targeted therapy for patients with HER2‐positive (HER2+) breast cancer has improved overall survival, but many patients still suffer relapse and death from the disease. …”
Publicado 2018
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
945por Janser, Félice A., Adams, Olivia, Bütler, Vanessa, Schläfli, Anna M., Dislich, Bastian, Seiler, Christian A., Kröll, Dino, Langer, Rupert, Tschan, Mario P.“…Patients with Her2 overexpressing breast and gastroesophageal cancer may benefit from Her2 inhibitors. …”
Publicado 2018
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
946“…At the 2018 ASCO Annual Meeting, data from several interesting studies in HER2-positive metastatic breast cancer were presented. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
947“…OBJECTIVE: To isolate and characterize novel high-affinity llama single-domain antibodies against human HER2. RESULTS: We immunized a llama with human HER2, constructed a phage-displayed V(H)H library from the lymphocytes of the animal, and isolated six unique HER2-specific V(H)Hs by panning. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
948por Triulzi, Tiziana, Forte, Luca, Regondi, Viola, Di Modica, Martina, Ghirelli, Cristina, Carcangiu, Maria Luisa, Sfondrini, Lucia, Balsari, Andrea, Tagliabue, Elda“…Through whole-transcriptome profiling of HER2+ breast carcinomas (BCs), we previously showed that those sensitive to trastuzumab are addicted to this oncoprotein and are enriched in immune pathways, raising the hypothesis that HER2 itself regulates immune cell recruitment. …”
Publicado 2018
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
949por Sanguedolce, Francesca, Russo, Davide, Mancini, Vito, Selvaggio, Oscar, Calo, Beppe, Carrieri, Giuseppe, Cormio, Luigi“…The aim of the present review was to summarize the existing evidence on HER2 status in MPBC, and to discuss its present and future utility in risk assessment and treatment choice of this uncommon, yet aggressive, disease.…”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
950“…Neratinib following the completion of trastuzumab has been shown to reduce the risk of disease recurrence for patients with HER2-positive early breast cancer in whom extended adjuvant therapy seems advisable. …”
Enlace del recurso
Online Artículo Texto -
951por Lambertini, Matteo, Demeestere, Isabelle, Viglietti, Giulia, de Azambuja, Evandro“…We observed similar rates of treatment-induced amenorrhea in the four anti-HER2 treatment arms. The lack of an increased rate of treatment-induced amenorrhea in the dual anti-HER2 blockade arm suggests the possible gonadal safety of these agents. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
952“…Pertuzumab (Perjeta) is an anti-HER2 monoclonal antibody that is used for treatment of HER2-positive breast cancers in combination with trastuzumab (Herceptin) and docetaxel and showed promising clinical outcomes. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
953por Moro Pérez, Leina, Rodríguez Taño, Azalia de la Caridad, Martín Márquez, Lázaro Roberto, Gómez Pérez, Jose Alberto, Valle Garay, Aisel, Blanco Santana, RancésEnlace del recurso
Publicado 2019
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
954por Al-Juboori, Shaymaa IK., Vadakekolathu, Jayakumar, Idri, Sarra, Wagner, Sarah, Zafeiris, Dimitrios, Pearson, Joshua RD., Almshayakhchi, Rukaia, Caraglia, Michele, Desiderio, Vincenzo, Miles, Amanda K., Boocock, David J., Ball, Graham R., Regad, Tarik“…The activation of PYK2 by metformin in pure HER2 phenotype (HER2+/ER−/PR-) cell lines was investigated by microarrays, quantitative real time PCR and immunoblotting. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
955
-
956“…The treatment of breast cancer has been revolutionized by the development of HER2-targeted treatments for patients who are HER2 positive. …”
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
957por Kong, Xiangyi, Zhang, Kai, Wang, Xiangyu, Yang, Xue, Li, Yalun, Zhai, Jie, Xing, Zeyu, Qi, Yihang, Gao, Ran, Feng, Xiaoli, Wang, Jing, Fang, Yi“…The present work aims to explore the mechanism of trastuzumab resistance caused by HER-2 mutation in breast carcinomas. Methods: Firstly, the HER2 wild type (WT) and HER2 mutant (HER2 Q429R, HER2 Q429H and HER2 T798M are the commonest 3 types of mutations) MCF7 cell lines were established. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
958por Nieto, Celia, Centa, Ariana, Rodríguez-Rodríguez, Jesús A., Pandiella, Atanasio, Martín del Valle, Eva M.“…Conjugated nanoparticles (300 nm) were characterized and their internalization in HER2-overexpressing tumor cells was analyzed by immunofluorescence. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
959por Seigel, Gail M, Shah, Dhaval K, Mendoza, Pia, Szalai, Ezster, Grossniklaus, Hans, Song, Yinghui, Shan, Jidong“…We also examined 28 RB tumors for HER2 protein immunoreactivity. 21/22 RB tumors expressed Her2 DNA and 14/19 tumors expressed Her2 RNA. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
960