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Mostrando 961 - 980 Resultados de 58,773 Para Buscar '"Her"', tiempo de consulta: 0.41s Limitar resultados
  1. 961
    “…Electrochemical perturbation, in the form of electrochemical potential scanning (linear sweep voltammetry), as induced when exploring the HER using monolayer graphene, creates defects upon the basal plane surface that increases the coverage of edge plane sites/defects resulting in an increase in the electrochemical reversibility of the HER process. …”
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    Investigating the Integrity of Graphene towards the Electrochemical Hydrogen Evolution Reaction (HER)
  2. 962
    “…Although the HER2-enriched is the most representative transcriptional subtype in the HER2-positive breast cancer, we can find it too in breast cancers with HER2-negative status. …”
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    Deciphering HER2 Breast Cancer Disease: Biological and Clinical Implications
  3. 963
    “…Human epidermal growth factor receptor 2 (HER2) is overexpressed/amplified in one third of breast cancers (BCs), and is associated with the poorer prognosis and the higher metastatic potential in BC. …”
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    Theranostic application of miR-429 in HER2+ breast cancer
  4. 964
    “…PMC is typically positive for estrogen receptors (ER) and progesterone receptors (PR) and negative for human epidermal growth factor receptor 2 (HER2). The clinicopathologic characteristics of HER2-positive PMC have not been investigated. …”
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    Clinicopathologic characteristics of HER2-positive pure mucinous carcinoma of the breast
  5. 965
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    The effect of synbiotic preparations on the intestinal microbiota and her metabolism in broiler chickens
  6. 966
    “…Here, we investigated whether HER2 colocalizes with focal adhesion complexes on breast cancer cells overexpressing HER2. …”
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    Anti-correlation of HER2 and focal adhesion complexes in the plasma membrane
  7. 967
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    ERBB2/HER2 mutations are transforming and therapeutically targetable in leukemia
  8. 968
    “…Neuregulin protein 1 (NRG1) is a large (> 60–amino-acid) natural peptide ligand for the ErbB protein family members HER3 and HER4. We developed an agonistic antibody modality, termed antibody ligand mimetics (ALM), by incorporating complex ligand agonists such as NRG1 into an antibody scaffold. …”
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    Long-acting antibody ligand mimetics for HER4-selective agonism
  9. 969
    “…Here, we investigate the feasibility of a novel HER2-targeted affibody-based conjugate (Z(HER2:2395)-IR700) selectively to induce cancer cell death in vitro and in vivo. …”
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    Immunomodulatory activity of IR700-labelled affibody targeting HER2
  10. 970
    “…HER3 (erbB3) signaling serves an important role in the development and chemoresistance of ovarian cancer, and is activated by chemotherapy. …”
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    Neoadjuvant chemotherapy promotes the expression of HER3 in patients with ovarian cancer
  11. 971
    por Kotani, Daisuke, Shitara, Kohei
    Publicado 2021
    “…Trastuzumab deruxtecan (T-DXd) is a novel anti-human epidermal growth factor receptor 2 (HER2) antibody–drug conjugate composed of a monoclonal anti-HER2 antibody and a topoisomerase I inhibitor, DX-8951 derivative (an exatecan derivative). …”
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    Trastuzumab deruxtecan for the treatment of patients with HER2-positive gastric cancer
  12. 972
    “…Functional activation of human epidermal growth factor receptor 2 (HER2) has been shown to strongly promote carcinogenesis, leading to the investigation of HER2-directed agents in cancers with HER2 genomic alterations. …”
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    Targeting HER2 expression in cancer: New drugs and new indications
  13. 973
    “…SIMPLE SUMMARY: Breast cancer can express, at varied levels, a protein named HER2, commonly responsible for making it grow and send distant metastases. …”
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    The Exciting New Field of HER2-Low Breast Cancer Treatment
  14. 974
    “…SIMPLE SUMMARY: The human epidermal growth factor receptor-2 (HER2) has been studied in many human carcinomas. …”
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    Immunohistochemical Screening of HER2 in Canine Carcinomas: A Preliminary Study
  15. 975
    “…HER2 targeted therapies have significantly improved prognosis of HER2-positive breast and gastric cancer. …”
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    Trastuzumab Deruxtecan: Changing the Destiny of HER2 Expressing Solid Tumors
  16. 976
    “…The objective of the study was to determine the effect of the size of the litter in which the sow was born on her lifetime reproductive performance. Data on 22,683 litters were used to analyse the lifetime reproductive performance of 5623 Polish Large White sows. …”
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    The Effect of the Size of the Litter in Which the Sow Was Born on Her Lifetime Productivity
  17. 977
    “…SIMPLE SUMMARY: About one third of all breast cancers are classified as HER2-positive due to high levels of the HER2 cell surface protein. …”
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    Targeting mTOR and Glycolysis in HER2-Positive Breast Cancer
  18. 978
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    Trastuzumab beyond progression in HER2‐positive metastatic breast cancer
  19. 979
    “…RESULTS: Among 731 patients who underwent sequencing, 55 patients (7.5%) had HER2 alteration, including 29 (4.0%) with HER2 somatic mutations, 24 (3.3%) with HER2 gene amplification, and 2 patients (0.2%) with both HER2 mutations and amplification. …”
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    Relationship of HER2 Alteration and Microsatellite Instability Status in Colorectal Adenocarcinoma
  20. 980
    “…The present study examined the association between HER2 expression and the histologic features of PCa subjected to radical prostatectomy (RP) and evaluated the role of testosterone suppression in HER2 expression. …”
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    The influence of testosterone suppression on HER2 immunoexpression in prostatic neoplastic tissue
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